| Cover | Apr. 17, 2023 |
| Cover [Abstract] | |
| Document Type | 8-K |
| Amendment Flag | false |
| Document Period End Date | Apr. 17, 2023 |
| Entity File Number | 001-38114 |
| Entity Registrant Name | Avenue Therapeutics, Inc. |
| Entity Central Index Key | 0001644963 |
| Entity Tax Identification Number | 47-4113275 |
| Entity Incorporation, State or Country Code | DE |
| Entity Address, Address Line One | 1111 Kane Concourse |
| Entity Address, Address Line Two | Suite 301 |
| Entity Address, City or Town | Bay Harbor Islands |
| Entity Address, State or Province | FL |
| Entity Address, Postal Zip Code | 33154 |
| City Area Code | 781 |
| Local Phone Number | 652-4500 |
| Written Communications | false |
| Soliciting Material | false |
| Pre-commencement Tender Offer | false |
| Pre-commencement Issuer Tender Offer | false |
| Title of 12(b) Security | Common Stock |
| Trading Symbol | ATXI |
| Security Exchange Name | NASDAQ |
| Entity Emerging Growth Company | false |
