Exhibit 23.1
Consent of Independent Registered Public Accounting Firm
We consent to the incorporation by reference in the Registration Statement (No.333-229140) on FormS-3 and Registration Statements (Nos.333-224018 and333-230282) on FormS-8 of Cue Biopharma, Inc. of our report dated March 11, 2020, relating to the consolidated financial statements of Cue Biopharma, Inc. and Subsidiary, appearing in this Annual Report on Form10-K of Cue Biopharma, Inc. for the year ended December 31, 2019.
/s/ RSM US LLP
Boston, Massachusetts
March 12, 2020
