| Document and Entity Information | Feb. 28, 2022 |
| Cover [Abstract] | |
| Amendment Flag | false |
| Entity Central Index Key | 0001652130 |
| Document Type | 8-K |
| Document Period End Date | Feb. 28, 2022 |
| Entity Registrant Name | INTELLIA THERAPEUTICS, INC. |
| Entity Incorporation State Country Code | DE |
| Entity File Number | 001-37766 |
| Entity Tax Identification Number | 36-4785571 |
| Entity Address, Address Line One | 40 Erie Street |
| Entity Address, Address Line Two | Suite 130 |
| Entity Address, City or Town | Cambridge |
| Entity Address, State or Province | MA |
| Entity Address, Postal Zip Code | 02139 |
| City Area Code | (857) |
| Local Phone Number | 285-6200 |
| Written Communications | false |
| Soliciting Material | false |
| Pre Commencement Tender Offer | false |
| Pre Commencement Issuer Tender Offer | false |
| Security 12b Title | Common Stock (Par Value $0.0001) |
| Trading Symbol | NTLA |
| Security Exchange Name | NASDAQ |
| Entity Emerging Growth Company | false |
