Exhibit 16.1
January 16, 2018
U.S. Securities and Exchange Commission
100 F Street, N.E.
Washington DC 20549
Re: CEN Biotech, Inc.
Ladies and Gentlemen:
We have read CEN Biotech, Inc.’s Form 8-K dated January 16, 2018, and are in agreement with the statements in Item 4.01 contained therein, as they relate to our firm.
Very truly yours,
/S/ Thayer O’Neal Company, LLC
Thayer O’Neal Company, LLC
Houston, Texas