Arvinas (ARVN) 10-K 16 Mar 20 2019 FY Annual report Financial data

Document and Entity Information

Document and Entity Information - USD ($)	12 Months Ended
	Dec. 31, 2019	Mar. 10, 2020	Jun. 28, 2019
Cover [Abstract]
Document Type	10-K
Amendment Flag	false
Document Period End Date	Dec. 31, 2019
Document Fiscal Year Focus	2019
Document Fiscal Period Focus	FY
Trading Symbol	ARVN
Entity Registrant Name	ARVINAS, INC.
Entity Central Index Key	0001655759
Current Fiscal Year End Date	--12-31
Entity Filer Category	Accelerated Filer
Entity Small Business	true
Entity Emerging Growth Company	true
Entity Ex Transition Period	true
Entity Well-known Seasoned Issuer	No
Entity Voluntary Filers	No
Entity Current Reporting Status	Yes
Entity Interactive Data Current	Yes
Entity Shell Company	false
Title of 12(b) Security	Common stock, par value $0.001 per share
Security Exchange Name	NASDAQ
Entity File Number	001-38672
Entity Incorporation, State or Country Code	DE
Entity Tax Identification Number	47-2566120
Entity Address, Address Line One	5 Science Park
Entity Address, Address Line Two	395 Winchester Ave
Entity Address, City or Town	New Haven
Entity Address, State or Province	CT
Entity Address, Postal Zip Code	06511
City Area Code	203
Local Phone Number	535-1456
Document Annual Report	true
Document Transition Report	false
Entity Public Float			$ 464,600,000
Entity Common Stock Shares Outstanding		39,076,828
Documents Incorporated by Reference	Part III of this Annual Report incorporates by reference information from the definitive Proxy Statement for the registrant’s 2020 Annual Meeting of Stockholders, which is expected to be filed with the Securities and Exchange Commission not later than 120 days after the registrant’s fiscal year ended December 31, 2019.

Consolidated Balance Sheets

Consolidated Balance Sheets - USD ($)	Dec. 31, 2019	Dec. 31, 2018
Current assets:
Cash and cash equivalents	$ 9,211,057	$ 3,190,056
Marketable securities	271,661,456	184,637,640
Account receivable		2,775,831
Other receivables	6,280,828	2,255,966
Prepaid expenses and other current assets	3,727,294	2,818,286
Total current assets	290,880,635	195,677,779
Property, equipment and leasehold improvements, net	8,455,411	3,583,036
Operating lease right of use assets	2,278,623
Other assets	26,757	20,760
Total assets	301,641,426	199,281,575
Current liabilities:
Accounts payable	4,556,827	2,758,184
Accrued expenses	7,602,904	4,001,276
Deferred revenue	19,979,525	16,065,957
Current portion of long-term debt		154,461
Current portion of operating lease liabilities	673,896
Total current liabilities	32,813,152	22,979,878
Deferred revenue	38,427,882	37,484,714
Long term debt, net of current portion	2,000,000	2,000,000
Operating lease liabilities	1,714,111
Other non-current liability		150,000
Total liabilities	74,955,145	62,614,592
Commitments and contingencies
Stockholders' equity:
Common stock, $0.001 par value, 38,461,353 and 31,235,458 shares issued and outstanding as of December 31, 2019 and 2018, respectively	38,461	31,236
Accumulated deficit	(372,556,846)	(302,264,619)
Additional paid-in capital	599,097,090	439,118,089
Accumulated other comprehensive income (loss)	107,576	(217,723)
Total stockholders' equity	226,686,281	136,666,983
Total liabilities and stockholders' equity	$ 301,641,426	$ 199,281,575

Consolidated Balance Sheets (Pa

Consolidated Balance Sheets (Parenthetical) - $ / shares	Dec. 31, 2019	Dec. 31, 2018
Statement Of Financial Position [Abstract]
Common Stock Par Or Stated Value Per Share	$ 0.001	$ 0.001
Common Stock Shares Issued	38,461,353	31,235,458
Common Stock Shares Outstanding	38,461,353	31,235,458

Consolidated Statements of Oper

Consolidated Statements of Operations - USD ($)	12 Months Ended
	Dec. 31, 2019	Dec. 31, 2018
Income Statement [Abstract]
Revenue	$ 42,976,478	$ 14,323,920
Operating expenses:
Research and development	67,193,830	45,193,830
General and administrative	27,307,162	12,932,168
Total operating expenses	94,500,992	58,125,998
Loss from operations	(51,524,514)	(43,802,078)
Other income (expenses)
Other income	1,435,596	102,730
Change in fair value of preferred unit warrant	0	(193,779)
Interest income	4,557,260	2,470,101
Interest expense	(85,569)	(57,440)
Total other income	5,907,287	2,321,612
Loss from equity method investment	(24,675,000)	0
Net loss	(70,292,227)	(41,480,466)
Change in redemption value of redeemable preferred units	0	(198,366,756)
Net loss attributable to common shares	$ (70,292,227)	$ (239,847,222)
Net loss per common share, basic and diluted	$ (2.13)	$ (25.45)
Weighted average common shares outstanding, basic and diluted	32,927,697	9,422,799

Consolidated Statements of Comp

Consolidated Statements of Comprehensive Loss - USD ($)	12 Months Ended
	Dec. 31, 2019	Dec. 31, 2018
Statement Of Income And Comprehensive Income [Abstract]
Net loss	$ (70,292,227)	$ (41,480,466)
Other comprehensive gain (loss):
Unrealized gain (loss) on available-for-sale securities	325,299	(207,972)
Comprehensive loss	$ (69,966,928)	$ (41,688,438)

Consolidated Statements of Rede

Consolidated Statements of Redeemable Convertible Preferred Shares/Units and Changes in Stockholders'/Members' Equity - USD ($)	Total	Accumulated Deficit	Additional Paid-in Capital	Accumulated Other Comprehensive Loss	Series A Redeemable Convertible Preferred Units	Series B Redeemable Convertible Preferred Units	Series C Redeemable Convertible Preferred Units	Series A,B and C Convertible Preferred Shares	Common UnitsMember Units	Common Shares	Incentive UnitsMember Units
Balance at Dec. 31, 2017					$ 19,768,025	$ 41,712,407
Balance, Units/Shares at Dec. 31, 2017					22,463,665	24,977,489
Balance at Dec. 31, 2017	$ (61,234,562)	$ (62,417,397)		$ (9,751)					$ 6,167		$ 1,186,419
Balance, Units/Shares at Dec. 31, 2017									1,897,544		3,669,963
Incentive unit/share-based compensation	11,630,300		$ 9,141,239								$ 2,489,061
Incentive unit/share-based compensation Units/Shares											1,680,386
Exercise of Series A redeemable convertible preferred warrant					$ 319,667
Exercise of Series A redeemable convertible preferred warrant, Units					110,116
Issuance of Series C redeemable convertible preferred units							$ 55,000,001
Issuance of Series C redeemable convertible preferred units, Units							16,467,066
Change in redemption value of redeemable convertible preferred units	(198,366,756)	(198,366,756)			$ 91,044,716	$ 81,253,577	$ 26,068,463
Net loss	(41,480,466)	(41,480,466)
Conversion of redeemable convertible preferred units to redeemable convertible preferred shares					$ (111,132,408)	$ (122,965,984)	$ (81,068,464)	$ 315,166,856
Conversion of redeemable convertible preferred units to redeemable convertible preferred shares, Units/Shares					(22,573,781)	(24,977,489)	(16,467,066)	64,018,336
Conversion of common and incentive units to common and restricted stock			3,677,954						$ (6,167)	$ 3,693	$ (3,675,480)
Conversion of common and incentive units to common and restricted stock, Units/Shares									(1,897,544)	3,692,765	(5,350,349)
Issuance of common stock, net of underwriters' discounts and issuance costs	111,159,583		111,151,883							$ 7,700
Issuance of common stock, net of underwriters' discounts and issuance costs, Shares										7,700,482
Conversion of redeemable convertible preferred stock to common stock	315,166,856		315,147,158					$ (315,166,856)		$ 19,698
Conversion of redeemable convertible preferred stock to common stock, Shares								(64,018,336)		19,697,928
Restricted stock vesting			(145)							$ 145
Restricted stock vesting, Shares										144,283
Unrealized gain (loss) on available-for-sale securities	(207,972)			(207,972)
Balance at Dec. 31, 2018	136,666,983	(302,264,619)	439,118,089	(217,723)						$ 31,236
Balance, Units/Shares at Dec. 31, 2018										31,235,458
Stock-based compensation	20,072,710		20,072,710
Net loss	(70,292,227)	(70,292,227)
Issuance of common stock, net of underwriters' discounts and issuance costs	137,088,875		137,082,302							$ 6,573
Issuance of common stock, net of underwriters' discounts and issuance costs, Shares										6,573,586
Restricted stock vesting			(475)							$ 475
Restricted stock vesting, Shares										475,412
Proceeds from exercise of stock options	2,824,641		2,824,464							$ 177
Proceeds from exercise of stock options, Shares										176,897
Unrealized gain (loss) on available-for-sale securities	325,299			325,299
Balance at Dec. 31, 2019	$ 226,686,281	$ (372,556,846)	$ 599,097,090	$ 107,576						$ 38,461
Balance, Units/Shares at Dec. 31, 2019										38,461,353

Consolidated Statements of Re_2

Consolidated Statements of Redeemable Convertible Preferred Shares/Units and Changes in Stockholders'/Members' Equity (Parenthetical) - USD ($)	12 Months Ended
	Dec. 31, 2019	Dec. 31, 2018
Statement Of Stockholders Equity [Abstract]
Issuance of common stock, underwriters' discounts and issuance costs	$ 7,497,131	$ 12,048,129

Consolidated Statements of Cash

Consolidated Statements of Cash Flows - USD ($)	12 Months Ended
	Dec. 31, 2019	Dec. 31, 2018
Cash flows from operating activities:
Net loss	$ (70,292,227)	$ (41,480,466)
Adjustments to reconcile net loss to net cash used in operating activities:
Amortization of debt discount	15,149	17,963
Change in fair value of preferred unit warrant liability	0	193,779
Depreciation and amortization	1,561,557	706,000
Net accretion of bond discounts/premiums	154,022	248,069
Amortization of right to use assets	691,345	0
Non-cash share/unit-based compensation	20,072,710	11,630,300
Changes in operating assets and liabilities:
Other receivables	(4,024,862)	(1,215,514)
Account receivable	2,775,831	22,224,169
Prepaid expenses and other current assets	(1,065,005)	(2,501,383)
Accounts payable	1,608,735	2,002,163
Accrued expenses	3,601,628	455,340
Deferred liability	0	150,000
Operating lease liabilities	(581,961)	0
Deferred revenue	4,856,736	(8,548,090)
Net cash used in operating activities	(40,626,342)	(16,117,670)
Cash flows from investing activities:
Purchase of marketable securities	(256,548,355)	(234,894,225)
Maturities of marketable securities	169,695,816	58,059,526
Purchase of property, equipment and leasehold improvements	(6,244,024)	(2,830,661)
Net cash used in investing activities	(93,096,563)	(179,665,360)
Cash flows from financing activities:
Repayments of long-term debt	(169,610)	(173,889)
Proceeds from long-term debt	0	2,000,000
Proceeds from issuance of common stock	137,686,006	114,583,172
Payment of common stock offering costs	(597,131)	(3,423,589)
Proceeds from issuance of Series C redeemable convertible preferred units	0	55,000,001
Proceeds from exercise of warrant	0	75,000
Proceeds from exercise of stock options	2,824,641	0
Net cash provided by financing activities	139,743,906	168,060,695
Net increase (decrease) in cash and cash equivalents	6,021,001	(27,722,335)
Cash and cash equivalents, beginning of the period	3,190,056	30,912,391
Cash and cash equivalents, end of the period	9,211,057	3,190,056
Supplemental disclosure of cash flow information:
Purchases of property, equipment and leasehold improvements unpaid at period end	189,908	159,494
Cash paid for interest	70,420	39,476
Increase in redemption value of preferred units	$ 0	$ 198,366,756

Nature of Business

Nature of Business	12 Months Ended
	Dec. 31, 2019
Organization Consolidation And Presentation Of Financial Statements [Abstract]
Nature of Business	1. Nature of Business Arvinas, Inc. has four wholly owned subsidiaries, Arvinas Operations, Inc., Arvinas Androgen Receptor, Inc., Arvinas Estrogen Receptor, Inc., and Arvinas Winchester, Inc. (collectively, the Company). Arvinas Operations, Inc. was formed in 2013, Arvinas Androgen Receptor, Inc. was formed in 2015, Arvinas Estrogen Receptor, Inc. was formed in 2016, and Arvinas Winchester, Inc. was formed in 2018. In September 2018, the Company converted from a Delaware limited liability company to a Delaware corporation. All periods prior to the date of conversion represent the results of the limited liability corporation. The Company is a clinical-stage biopharmaceutical company dedicated to improving the lives of patients suffering from debilitating and life-threatening diseases throughout the discovery, development and commercialization of therapies to degrade disease-causing proteins. Arvinas, Inc. was incorporated in Delaware on July 3, 2013. Effective January 1, 2015, Arvinas Holding Company, LLC (Arvinas LLC) was formed by the shareholders of Arvinas, Inc. and Arvinas, Inc. became a wholly owned subsidiary of Arvinas LLC. In connection with this reorganization, the rights and preferences of the preferred stock of Arvinas, Inc. were exchanged for preferred stock units with similar rights and preferences of Arvinas LLC. As part of the reorganization, the employees, consultants and board members of Arvinas, Inc. exchanged their stock options in Arvinas, Inc. stock in exchange for incentive units in Arvinas LLC. Additionally, common stockholders of Arvinas, Inc. exchanged their common stock for common units in Arvinas LLC. All exchanges were made on a 1-for-1 basis. This reorganization was accounted for as a common control transaction as the common stockholders of Arvinas, Inc. formed Arvinas, LLC and transferred all the assets from Arvinas, Inc. to Arvinas LLC. The Company’s Board of Managers approved a one-for-3.25 reverse stock split of its issued and outstanding shares of common units and a proportional adjustment to the existing conversion ratios for the Company’s Series A, Series B, and Series C preferred units effective as of September 14, 2018. Accordingly, all share/unit and per share/unit amounts for all periods presented in the accompanying financial statements and notes thereto have been retroactively adjusted, where applicable, to reflect this reverse unit split and adjustment of the preferred unit conversion ratios. Immediately prior to the effectiveness of the registration statement pertaining to the Company’s initial public offering on September 26, 2018, the Company converted from a Delaware limited liability company to a Delaware corporation. Pursuant to the plan of conversion, each outstanding Series A, Series B, and Series C preferred units converted into an equal number of shares of Series A, Series B, and Series C preferred stock, each outstanding common unit converted into a share of common stock and each outstanding incentive unit converted into a number of shares of common stock and restricted common stock based on a conversion price determined by the board of directors. The Company issued 1,795,221 shares of common stock and 1,268,923 shares of restricted common stock. On October 1, 2018, the Company completed an initial public offering (IPO) in which the Company issued and sold 7,500,000 shares On October 1, 2018, all of the outstanding shares of convertible preferred stock automatically converted into 19,697,928 shares of common stock at the applicable conversion ratio then in effect. Subsequent to the closing of the IPO, there were no shares of preferred stock outstanding.

Summary of Significant Accounti

Summary of Significant Accounting Policies	12 Months Ended
	Dec. 31, 2019
Accounting Policies [Abstract]
Summary of Significant Accounting Policies	2. Summary of Significant Accounting Policies Principles of Consolidation The consolidated financial statements of the Company include the accounts of Arvinas, Inc. and its wholly owned subsidiaries. All intercompany transactions have been eliminated in consolidation. Use of Estimates The preparation of the Company’s consolidated financial statements in conformity with accounting principles generally accepted in the United States requires management to make certain estimates and assumptions that affect the reported amounts and disclosures in the financial statements. While management believes that estimates and assumptions used in the preparation of the consolidated financial statements are appropriate, actual results could differ from those estimates. The most significant estimates are those used in determination of the Company’s revenue recognition, fair value of its common and preferred units, preferred unit warrant liability, incentive equity compensation, and fair value of its investment in a joint venture (Oerth). Financial Instruments The Company’s principal financial instruments comprise cash, marketable securities, account receivable, accounts payable, accrued liabilities and long-term debt. The carrying value of all financial instruments approximates fair value. Cash and Cash Equivalents The Company classifies as cash and cash equivalents amounts on deposit in banks and cash invested temporarily in various instruments, primarily money market accounts, with original maturities of three months or less at time of purchase. The carrying amounts reported in the consolidated balance sheets represent the fair values of cash and cash equivalents. Concentration of Credit Risk The Company maintains its cash in financial institution accounts that, at times during the year, may exceed federally insured limits. The cash balances in the financial institutions are insured by the Federal Deposit Insurance Corporation (FDIC) up to $250,000. Cash may also be maintained at commercial institutions that are not insured by the FDIC. For the year ended December 31, 2019, 57% of the Company’s revenue was attributable to a license contributed to a joint venture, Oerth Bio LLC (Oerth), and two collaborators represented 19% and 16% of total revenue. For the year ended December 31, 2018, two collaborators each represented over 45% of total revenue. One collaborator accounted for the entire account receivable balance at December 31, 2018. Marketable Securities The Company classifies its marketable securities as available-for-sale securities, which are carried at their fair value based on the quoted market prices of the securities with unrealized gains and losses reported as accumulated other comprehensive loss, a separate component of members’ equity. Realized gains and losses on available-for-sale securities are included in net earnings in the period earned or incurred. Property, Equipment, and Leasehold Improvements Property and equipment are recorded at cost. Depreciation is calculated using the straight-line method over the estimated useful lives, which range from three years for office equipment to five years for laboratory equipment. Maintenance and repairs which do not extend the lives of the assets are charged directly to expense as incurred. Upon retirement or disposal, cost and related accumulated depreciation are removed from the related accounts, and any resulting gain or loss is recognized as a component of income or loss for the period. Leasehold improvements are recorded at cost and amortized using the straight-line method over the shorter of the lease term or the useful life of the asset. Impairment of Long-Lived Assets When indications of potential impairments are present, the Company evaluates the carrying value of long-lived assets. The Company adjusts the carrying value of the long-lived assets if the sum of undiscounted expected future cash flows is less than carrying value. No such impairments were recorded during 2019 or 2018. Deferred Financing Costs Deferred financing costs are being amortized over the term of the related debt. Segment Information The Company manages its operations as a single segment for the purposes of assessing performance and making operating decisions. All of the Company’s tangible assets are held in the United States. To date, all of the Company’s revenue has been generated in the United States. Revenue Recognition and Deferred Revenue Revenues from Contracts The Company recognizes revenue under Accounting Standards Codification (ASC) 606, Revenue from Contracts with Customers. The research collaboration and license agreements typically include contingent milestone payments related to specified preclinical and clinical development milestones and regulatory milestones. These milestone payments represent variable consideration to be included within the transaction price using the most likely amount method. The Company determined that the most likely amount to be recognized was zero, against which no constraint was applied. The Company will continue to assess the probability of significant reversals for any amounts that become likely to be realized prior to recognizing the variable consideration associated with these payments within the transaction price. Revenue is recognized ratably over the Company’s expected performance period under each respective arrangement. The Company makes its best estimate of the period over which the Company expects to fulfill the Company’s performance obligations, which includes access to technology through the license agreement and research activities. Given the uncertainties of these collaboration arrangements, significant judgment is required to determine the duration of the performance period. For the years ended December 31, 2019 and 2018, the transaction price allocated to the combined performance obligation identified under the agreements is recognized as revenue on a straight-line basis over the estimated performance period under each respective arrangement. Straight-line basis was considered the best measure of progress in which control of the combined obligation transfers to the customers, due to the contract containing license rights to technology, research and development services, and joint committee participation, which in totality are expected to occur ratably over the performance period. The Company’s contracts may also call for certain sales-based milestone and royalty payments upon successful commercialization of a target. The Company recognizes revenues from sales-based milestone and royalty payments at the later of a) the occurrence of the subsequent sale; or b) the performance obligation to which some or all of the sales-based milestone or royalty payments has been allocated has been satisfied (or partially satisfied). The Company anticipates recognizing these milestones and royalty payments if and when subsequent sales are generated by the customer from the use of the technology. To date, no revenue from these sales-based milestone and royalty payments has been recognized for any periods. Amounts received prior to satisfying the above revenue recognition criteria are recorded as a contract liability in the Company’s accompanying consolidated balance sheets. The Company also recognized revenue under ASC 606 from its contribution of a license to Oerth. See Note 12. Equity Method Investments The Company accounts for investments for which it does not have a controlling interest in accordance with ASC 323, Investments – Equity Method and Joint Ventures Preferred Unit Warrants Preferred unit warrants issued in conjunction with debt financings were initially recorded at fair value, using a Black-Scholes option pricing model, with a corresponding discount recorded against the face value of the note and a liability. The discount was then accreted against the face value of the note over its remaining term as additional interest expense. The Company classified warrants to purchase shares of its Series A Redeemable Convertible Preferred Units (Series A Preferred Units) as a liability on its balance sheets as these warrants were free-standing financial instruments that were exercisable for contingently redeemable shares. The preferred unit warrants were recorded in long-term liabilities at fair value, estimated using the Black-Scholes option pricing model, and marked to market at each balance sheet date. The change in carrying value was reported as the change in fair value of warrant liability in the accompanying consolidated statements of operations. The outstanding warrants were exercised in July 2018 and no warrants were outstanding as of December 31, 2019 and 2018. Income Taxes Prior to the conversion to a C-corporation, Arvinas LLC was taxed under the provisions of Subchapter K—Partners and Partnerships of the Internal Revenue Code. Under those provisions, Arvinas LLC did not pay federal or state corporate income taxes on its taxable income. Instead, each member would include net operating income or loss for Arvinas LLC on its individual return. Arvinas LLC was converted to a C-corporation in 2018. Arvinas, Inc. and its wholly owned subsidiaries use the asset and liability method of accounting for income taxes, as set forth in ASC 740, Accounting for Income Taxes Management has evaluated the effect of ASC 740 guidance related to uncertain income tax positions and concluded that the Company has no significant uncertain income tax positions at December 31, 2019 and 2018. Equity-based Compensation Prior to its IPO, the Company periodically granted incentive units to employees and non-employees, which generally vested over a four-year period. The incentive units represented a separate substantive class of equity with defined rights within the LLC Operating Agreement. The incentive units represented profits interests in the Company, which was an interest in the increase in the value of the entity over the Participation Threshold, as defined in the LLC Operating Agreement and as determined at the time of grant. The holder, therefore, had the right to participate in distributions of profits only in excess of the Participation Threshold. The Participation Threshold was based on the valuation of the common unit on or around the grant date. The Company accounted for incentive units granted in accordance with ASC 718, Compensation-Stock Compensation The Company measures employee and board of director equity-based compensation for stock option and restricted stock grants based on the grant date fair value of the equity awards. Equity-based compensation expense is recognized over the requisite service period of the awards, net of estimated forfeitures. Estimated forfeitures are updated on a periodic basis based on actual experience. For equity awards that have a performance condition, the Company recognizes compensation expense based on its assessment of the probability that the performance condition will be achieved. The Company measures equity awards granted to consultants based on the fair value of the award on the date the award is granted. Compensation expense is recognized over the period during which services are rendered by such consultants until completed. The Company classifies equity-based compensation expense in its consolidated statement of operations in the same manner in which the award recipient’s salary and related costs are classified or in which the award recipient’s service payments are classified. Research and Development Research and development costs are expensed as incurred. The Company records grants from governmental and non-profit agencies as a reduction in research and development expense. Grants are recognized when there is reasonable assurance that the Company will comply with the conditions attached to the grant arrangement and the grant will be received. Grant payments received related to research and development costs incurred prior to the approval of the qualifying program are recognized immediately upon approval of the program by the grantor. Fair Value Measurements ASC Topic 820, Fair Value Measurements and Disclosures Financial Instruments Level 1—Inputs are based upon observable or quoted prices for identical instruments traded in active markets. Level 2—Inputs are based upon quoted prices for similar instruments in active markets, quoted prices for identical or similar instruments in markets that are not active, and model-based valuation techniques for which all significant assumptions are observable in the market or can be corroborated by observable market data for substantially the full term of the assets or liabilities. The Company’s Level 2 investments consist primarily of corporate notes and bonds and U.S. government and agency securities. Level 3—Inputs are generally unobservable and typically reflect management’s estimates of assumptions that market participants would use in pricing the asset or liability. The fair values are therefore determined using model-based techniques that include option pricing models, discounted cash flow models, and similar techniques. In determining fair value, the Company utilizes valuation techniques that maximize the use of observable inputs and minimize the use of unobservable inputs to the extent possible as well as considers counterparty credit risk in its assessment of fair value. The Company’s marketable securities consist of corporate bonds and government securities which are adjusted to fair value each balance sheet date, based on quoted prices, which are considered Level 2 inputs (see Note 5). During the year ended December 31, 2019, a non-recurring fair value measurement was applied to determine the fair value of the non-cash consideration of 50% equity ownership received related to Oerth. The fair value measurement was determined using an income approach based primarily on utilizing management’s estimates of future cash flows as inputs, which are considered Level 3 measurements within the above fair value hierarchy. The following tables summarize the fair values and levels within the fair value hierarchy in which the fair value measurements fall for assets and liabilities measured on a recurring basis as of: December 31, 2019 Description Level 1 Level 2 Level 3 Total Assets: Corporate bonds $ — $ 271,661,456 $ — $ 271,661,456 December 31, 2018 Description Level 1 Level 2 Level 3 Total Assets: Corporate bonds $ — $ 181,668,600 $ — $ 181,668,600 Government securities — 2,969,040 — 2,969,040 The following table presents the changes in Level 3 instruments, preferred unit warrant, measured on a recurring basis for the year ended December 31, 2018: Preferred Unit Warrant Balance at December 31, 2017 $ 50,888 Change in fair value 193,779 Exercise of warrant (244,667 ) Balance at December 31, 2018 $ — Fluctuation in the fair value of the Company’s Series A Preferred Units was the primary driver for the change in the Preferred Unit Warrant liability valuation during each year prior to its exercise. As the fair value of the Series A Preferred Units increase, the value to the holder of the instrument generally increases. Additionally, unit price volatility is one of the significant unobservable inputs used in the fair value measurement of the Company’s Preferred Unit Warrant liability. A decrease in expected volatility would generally result in a lower fair value measurement. The carrying value of accounts payable and accrued expenses approximate their fair value due to the short‑term nature of these assets and liabilities. Net Loss per Common Share Basic net loss per common share is computed by dividing net loss, after adjusting for redeemable preferred unit dividends, by the weighted-average number of common shares outstanding during the period. The change in current redemption value of the redeemable preferred units was treated as a deemed dividend for the period during 2018 prior to conversion to common units. Diluted net loss per share was computed using the weighted-average number of common shares outstanding during the period and, if dilutive, the weighted average number of potential shares of common shares. The effect of the conversion of redeemable preferred units into common units was excluded from the computation of diluted net loss per common share for all periods as their effect was antidilutive. Additionally, common share equivalents are excluded from the computation of diluted net loss per common share for all periods as their effect is antidilutive. New Accounting Pronouncements Recently Adopted Accounting Pronouncements In February 2016, the Financial Accounting Standards Board (FASB) issued ASU No. 2016-02, Leases In June 2018, the FASB issued ASU No. 2018-07 , Improvements in Nonemployee Share-Based Payment Accounting Other accounting standards that have been issued by the FASB or other standards-setting bodies that do not require adoption until a future date are not expected to have a material impact on the Company’s financial statements upon adoption.

License Agreements

License Agreements	12 Months Ended
	Dec. 31, 2019
License Agreements [Abstract]
License Agreements	3. License Agreements In July 2013, the Company entered into an exclusive license agreement, including the right to grant sublicenses, with Yale University to develop protein degradation technologies. In connection with the execution of this license agreement, the Company made a non-refundable upfront payment of $149,511. In addition to the upfront payment, the Company paid Yale University a License Maintenance Royalty of varying amounts through the fourth anniversary of the license agreement. After 2017 and until the first sale to a third party of any licensed product, the minimum annual payment will be $75,000. The Company is also required to pay Yale University success-based milestones for the development of the protein degradation technologies as well as low single-digit running royalties on aggregate worldwide net sales of certain licensed products, which may be subject to reductions, and subject to a minimum royalty payment that ranges from $200,000 to $500,000. The agreement requires that, if the Company sublicenses the protein degradation technologies to a third party, the Company must pay Yale University a mid-single digit to mid-double digit percentage of Sublicense Income (as defined in the agreement) received on the first licensed product therewith. During 2015, the Company paid $750,000 to Yale University for sublicense consideration, representing the maximum amount required to be paid for sublicense consideration for a licensed product and satisfying this obligation. During 2019 and 2018, the Company paid $150,000 and $75,000, respectively, under the license agreement. The Company is also required to reimburse Yale University for patent costs incurred. During 2019 and 2018, the Company reimbursed Yale University $352,663 and $216,093, respectively, for patent costs.

Research Collaboration and Lice

Research Collaboration and License Agreements	12 Months Ended
	Dec. 31, 2019
Research Collaboration And License Agreements [Abstract]
Research Collaboration and License Agreements	4. Research Collaboration and License Agreements In June 2019, the Company and Bayer AG entered into a Collaboration and License Agreement (Bayer Collaboration Agreement) setting forth the Company’s collaboration with Bayer AG to identify or optimize proteolysis targeting chimeras, or PROTAC® targeted protein degraders, that mediate for degradation of target proteins (Targets), using the Company’s proprietary platform technology, which Targets will be selected by Bayer AG, subject to certain exclusions and limitations. The Bayer Collaboration Agreement became effective in July 2019. Under the terms of the Bayer Collaboration Agreement, the Company received an upfront non-refundable payment of $17.5 million in exchange for the use of the Company’s technology license. The Company also received a $1.5 million payment to fund research activities and Bayer is committed to funding an additional $10.5 million through 2022. These payments are being recognized over the total estimated period of performance. The Company is also eligible to receive up to $197.5 million in development milestone payments and up to $490.0 million in sales-based milestone payments for all designated Targets. In addition, the Company is eligible to receive, on net sales of PROTAC targeted protein degrader-related products, mid-single digit to low-double digit tiered royalties, which may be subject to reductions. The Company determined that the Bayer Collaboration Agreement and a Stock Purchase Agreement entered into with Bayer AG at the same time should be evaluated as a combined contract in accordance with ASC 606, Revenue from Contracts with Customers Contracts in Entity’s Own Equity In December 2017, the Company entered into a Research Collaboration and License Agreement with Pfizer, Inc. Under the terms of the agreement, the Company received an upfront non-refundable payment and certain additional payments totaling $28.0 million in 2018 in exchange for use of the Company’s technology license and to fund Pfizer-related research as defined within the agreement. These payments are being recognized as revenue over the total estimated period of performance. The Company is also eligible to receive up to an additional $37.5 million in non-refundable option payments if Pfizer exercises its options for all targets under the agreement. The Company is also entitled to receive up to $225 million in development milestone payments and up to $550 million in sales-based milestone payments for all designated targets under the agreement, as well as tiered royalties based on sales. Pfizer exercised an option for $2.5 million in December 2018 and the amount was included in account receivable at December 31, 2018. Pfizer also paid the Company $1.2 million relating to adding an additional target into the collaboration in December 2019. These payments are being recognized over the estimated period of performance. In September 2015, the Company entered into an Option and License Agreement with Genentech, Inc. and F. Hoffman-La Roche Ltd (the Genentech Agreement). During 2015, the Company received an upfront non-refundable payment of $11.0 million in exchange for use of the Company’s technology license and to fund Genentech-related research as defined within the Genentech Agreement. In November 2017, the Company entered into an Amended and Restated Option, License, and Collaboration Agreement with Genentech, Inc. and F. Hoffman-La Roche Ltd (the Genentech Modification), amending the Genentech Agreement. Under the Genentech Modification, the Company received additional upfront non-refundable payments of $34.5 million to fund Genentech-related research and Genentech has the right to designate up to ten targets. Upfront non-refundable payments are recognized as revenue over the total estimated period of performance. The Company is eligible to receive up to $44.0 million per target in development milestone payments, $52.5 million in regulatory milestone payments and $60.0 million in commercial milestone payments based on sales as well as tiered royalties based on sales. In connection with the Genentech Modification, the Company recognized an increase in revenue previously recognized of $0.4 million due to the offsetting impacts effect of an increase in total transaction price and an increase in expected period of performance. Information about contract liabilities, included as deferred revenue in the accompanying Consolidated Balance Sheets, is as follows: 2019 2018 Contract liabilities $ 58,407,408 $ 53,550,671 Revenues recognized in the period from: Amounts included in deferred revenue in previous periods 14,335,188 13,553,136 Changes in deferred revenue from 2018 to 2019 were due to billings of $23.1 million under new and modified contracts and $18.3 million of revenue recognized on the research collaboration and license agreements. The aggregate amount of the transaction price allocated to performance obligations that are unsatisfied as of December 31, 2019 was $58.4 million, which is expected to be recognized as follows (in millions): 2020 $ 20.0 2021 19.7 2022 13.9 2023 4.8 $ 58.4

Marketable Securities

Marketable Securities	12 Months Ended
	Dec. 31, 2019
Investments Debt And Equity Securities [Abstract]
Marketable Securities	5. Marketable Securities The following is a summary of the Company’s available-for-sale securities as of December 31, 2019 and 2018. December 31, 2019 Description Effective Maturity Amortized Cost Gross Unrealized Gains Gross Unrealized Losses Fair Value Corporate bonds 2020 145,359,876 49,722 - 145,409,598 Corporate bonds 2021 126,194,004 57,854 - 126,251,858 Total $ 271,553,880 $ 107,576 $ - $ 271,661,456 December 31, 2018 Description Effective Maturity Amortized Cost Gross Unrealized Gains Gross Unrealized Losses Fair Value Corporate bonds 2019 $ 154,859,427 $ — $ (165,630 ) $ 154,693,797 Government bonds 2019 2,966,262 2,778 — 2,969,040 Corporate bonds 2020 27,029,673 (54,870 ) 26,974,803 Total $ 184,855,362 $ 2,778 $ (220,500 ) $ 184,637,640

Property, Equipment and Leaseho

Property, Equipment and Leasehold Improvements	12 Months Ended
	Dec. 31, 2019
Property Plant And Equipment [Abstract]
Property, Equipment and Leasehold Improvements	6. Property, Equipment and Leasehold Improvements Property, equipment and leasehold improvements consist of the following at December 31: 2019 2018 Laboratory equipment $ 8,045,179 $ 3,757,265 Office equipment 865,888 577,418 Leasehold improvements 2,809,205 981,884 11,720,272 5,316,567 Less: accumulated depreciation (3,264,861 ) (1,733,531 ) Property, equipment and leasehold improvements, net $ 8,455,411 $ 3,583,036 Depreciation expense totaled $1,561,557 and $706,000 for the years ended December 31, 2019 and 2018, respectively.

Right to Use Assets and Liabili

Right to Use Assets and Liabilities	12 Months Ended
	Dec. 31, 2019
Leases [Abstract]
Right to Use Assets and Liabilities	7. Right to Use Assets and Liabilities During 2019, the Company obtained right of use assets (ROU) in exchange for lease liabilities of $571,885. The Company determines if an arrangement is a lease at inception. Operating leases are included in operating lease ROU assets and operating lease liabilities in the condensed consolidated balance sheets. ROU assets represent the right to use an underlying asset for the lease term and lease liabilities represent the obligation to make lease payments arising from the lease. Operating lease ROU assets and liabilities are recognized at the commencement date based on the present value of lease payments over the lease term. As the Company’s leases do not provide an implicit rate, the Company uses its incremental borrowing rate based on the information available at the commencement date in determining the present value of lease payments. The incremental borrowing rate was 5.1 – 6.6%. Lease expense for lease payments is recognized on a straight-line basis over the lease term. Some of the Company’s leases include options to extend or terminate the lease. The Company includes these options in the recognition of the Company’s ROU assets and lease liabilities when it is reasonably certain that the Company will exercise the option. The Company has operating leases for its corporate office and certain equipment, which expire no later than December 31, 2022. The leases have a weighted average remaining term of 2.9 years. Maturities of lease liabilities for the years ending December 31 are: 2020 775,734 2021 912,465 2022 895,847 Total lease payments 2,584,046 Less: imputed interest (196,039 ) Total $ 2,388,007 The operating lease cost for the year ended December 31, 2019 was $817,057. The operating cash flows used for operating leases for the year ended December 31, 2019 was $581,961. Prior to January 1, 2019, the Company accounted for its leases in accordance with ASC Topic 840, Leases

Accrued Expenses

Accrued Expenses	12 Months Ended
	Dec. 31, 2019
Payables And Accruals [Abstract]
Accrued Expenses	8. Accrued Expenses Accrued expenses consisted of the following at December 31: 2019 2018 Employee expenses $ 5,810,723 $ 2,795,205 Research and development expenses 1,186,935 357,148 Professional fees and other 605,246 848,923 $ 7,602,904 $ 4,001,276

Long-Term Debt

Long-Term Debt	12 Months Ended
	Dec. 31, 2019
Debt Disclosure [Abstract]
Long-Term Debt	9. Long-Term Debt In August 2013, the Company entered into a Loan Agreement (Loan) and a Stock Subscription Warrant, with Connecticut Innovations, Incorporated (CII). Under the Loan, the Company could draw up to $750,000 for the purpose of purchasing laboratory equipment, information technology equipment and leasehold improvements. Leasehold improvements are limited to $100,000. Interest on the Loan was compounded on a monthly basis at a rate of 7.50% per annum and was required to be paid on a monthly basis beginning on the date of the first draw of funds for 10 months, then with principal payments beginning on June 1, 2015 and payable monthly until the maturity date of July 31, 2019. The Company had the ability to prepay the amount due at any time prior to the maturity date without premium or penalty. The Loan was secured by substantially all of the Company’s assets. As of December 31, 2018, the amount outstanding under the Loan was $169,610 and the total unamortized debt discount on the Loan totaled $7,210. The Company paid the loan in full in July 2019. Interest expense recorded related to the amortization of the debt discount in the years ended December 31, 2019 and 2018 was $7,210 and $12,359, respectively. In connection with the issuance of the Loan, and as additional consideration, the Company granted CII a warrant to purchase 110,116 shares of the Company’s Series A Preferred Stock at a purchase price of $0.6811 per share, with a term of 7 years from the date of issuance. Effective January 1, 2015, this warrant was exchanged for a warrant to purchase 110,116 units of the Company’s Series A redeemable convertible preferred units. The warrant was exercised in July 2018. In connection with an Assistance Agreement with the State of Connecticut (Assistance Agreement) entered into in 2014, under which all the borrowings by the Company were forgiven in accordance with the Assistance Agreement, the Company is required to be located in the State of Connecticut through January 2024, with a default penalty of repayment of the full original funding amount of $2.5 million plus liquidated damages of 7.5%. In June 2018, the Company entered into an Assistance Agreement with the State of Connecticut (2018 Assistance Agreement) to provide funding for the expansion and renovation of laboratory and office space (Project). Under the terms of the 2018 Assistance Agreement, the Company could borrow from the State of Connecticut a maximum of $2.0 million, provided that the funding does not exceed more than 50% of the total Project costs. In September 2018, the Company borrowed $2.0 million under the 2018 Assistance Agreement, bearing interest at 3.25% per annum and interest payments will be required for the first 60 months from the funding date. Thereafter, the loan begins to fully amortize through month 120, maturing in June 2028. According to the terms of the 2018 Assistance Agreement, up to $1.0 million of the funding can be forgiven if the Company meets certain employment conditions, as defined in the agreement. The Company may also be required to prepay a portion of the loan if the employment conditions are not met. The 2018 Assistance Agreement requires that the Company be located in the State of Connecticut through June 2028 with a default penalty of repayment of the full original funding amount of $2.0 million plus liquidated damages of 7.5% of the total amount of funding received. Anticipated future minimum payments on long-term debt for the years ending December 31 are: 2023 $ 92,480 2024 377,516 Beyond 5 years 1,530,004 Total $ 2,000,000 During the years ended December 31, 2019 and 2018, interest expense was $85,569 and $57,440, respectively.

Members_ Equity

Members’ Equity	12 Months Ended
	Dec. 31, 2019
Debt Disclosure [Abstract]
Members' Equity	10. Members’ Equity Common Units Each common unit entitled the holder to one vote on all matters submitted to a vote of the Company’s members. As noted in Note 1, in September 2018, all issued and outstanding common units were converted into common stock. Preferred Units During 2013 and 2014, Arvinas, Inc. sold 22,463,665 shares of Series A Redeemable Convertible Preferred Stock (Series A Preferred Stock) for $15.3 million at a price of $0.6811 per share. The Series A Preferred Stock was subsequently exchanged for Series A Preferred Units in Arvinas LLC upon the reorganization. During 2015, the Company sold 24,977,489 Series B Redeemable Convertible Preferred Units (Series B Preferred Units) in exchange for $41.6 million at a price of $1.6659 per share. In March 2018, the Company entered into a Series C Preferred Unit Purchase Agreement (the Series C Agreement) to raise additional equity. Under the terms of the Series C Agreement, the Company sold 16,467,066 units of Series C Redeemable Convertible Preferred Units (Series C Preferred Units) for $55.0 million at a price of $3.34 per unit.

Equity

Equity	12 Months Ended
	Dec. 31, 2019
Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]
Equity	11. Equity In June 2019, the Company entered into a Stock Purchase Agreement with Bayer AG pursuant to which, in connection with the closing in July 2019, the Company issued and sold to Bayer AG 1,346,313 shares of the Company’s common stock (the Shares) for a contractually stated purchase price of approximately $32.5 million. The value of the shares of the Company’s common stock was based on the average of the Company’s In November 2019, the Company completed a public offering in which the Company issued and sold 5,227,273 shares of common stock at a public offering price of $22.00 per share. The Company’s aggregate gross proceeds from the sale of shares in the public offering was $115.0 million before fees and expenses of $7.4 million. In the Fourth Amendment to the Company’s Incentive Share Plan (the Incentive Plan) adopted in March 2018, the Company was authorized to issue up to an aggregate of 6,199,477 incentive units pursuant to the Incentive Plan. Generally, incentive units were granted at no less than fair value as determined by the board of managers and had vesting periods ranging from one to four years. The Incentive Plan was terminated in September 2018. In September 2018, the Company’s board of directors adopted and the Company’s stockholders approved the 2018 Stock Incentive Plan (the 2018 Plan), which became effective upon the effectiveness of the registration statement on Form S-1 for the Company’s IPO. The number of common shares initially available for issuance under the 2018 Plan equaled the sum of (1) 4,067,007 shares of common stock; plus (2) the number of shares of common stock (up to 1,277,181) issued in respect of incentive units granted under the Incentive Plan that are subject to vesting immediately prior to the effectiveness of the registration statement that expire, terminate or are otherwise surrendered, cancelled, forfeited or repurchased by the Company at their original issuance price pursuant to a contractual repurchase right; plus (3) an annual increase on the first day of each fiscal year beginning with the fiscal year ending December 31, 2019 and continuing to, and including, the fiscal year ending December 31, 2028, equal to the lowest of 4,989,593 shares of the Company’s common stock, 4% of the number of shares of the Company’s common stock outstanding on the first day of the fiscal year and an amount determined by the Company’s board of directors. The increase in the number of authorized shares for the fiscal year ending December 31, 2019 was 1,293,510. Common shares subject to outstanding equity awards that expire or are terminated, surrendered, or cancelled without having been fully exercised or are forfeited in whole or in part shall be available for future grants of awards. During 2018, the Company granted 1,715,368 incentive units to employees and directors under the Incentive Plan. In September 2018, each outstanding incentive unit was converted into a number of shares of common stock based upon the IPO price. Certain of the shares of common stock issued in respect of incentive units continue to be subject to vesting in accordance with the vesting schedule that was applicable to such incentive units, The Company granted 1,253,263 restricted shares to employees and directors as part of the conversion. The Company also granted 1,744,650 stock options to purchase shares of common stock to employees and directors who were holders of incentive units at the time of the incentive unit conversion and 286,307 in new employee grants. During 2019, the Company granted 1,468,983 stock options to purchase shares of common stock to employees and directors and restricted stock units with respect to 192,882 shares of common stock. The weighted average fair value of stock options granted to employees and directors in 2019 was $13.28 per share. The options granted generally vest over a requisite service period of four years with a maximum contractual life of ten years from date of grant. During 2019 and 2018, the Company recognized compensation expense of $18,660,743 and $10,026,666, respectively, relating to the issuance of employee incentive awards, and at December 31, 2019, there was $15,484,188 of compensation expense that is expected to be recognized over a weighted average period of approximately 1.6 years. In September 2018, in connection with the conversion of the incentive units, the Company granted 11,097 restricted shares of common stock and 251,010 stock options to purchase shares of common stock to consultants and, subsequently, granted 10,000 stock options to purchase shares of common stock to a new consultant. During 2019, the Company granted 51,695 stock options to purchase shares of common stock to consultants. During 2019, the Company recognized compensation expense of $1,411,967 relating to incentive share awards for consultants and, at December 31, 2019, there was $895,816 of compensation expense remaining to be amortized over a weighted average period of less than 1.3 years. The fair value of the incentive units granted during the year ended December 31, 2018 was determined using the Black-Scholes option pricing model with the following assumptions: 2018 Expected volatility 66 - 71% Expected term (years) 5.6 - 6.1 Risk free interest rate 2.5 - 2.9% Expected dividend yield 0% Fair value of underlying common units $1.08 - 8.48 The fair value of the underlying common units indicated above was utilized as the exercise price within the Black-Scholes option pricing model. The fair value of the stock options granted during the year ended December 31, 2019 was determined using the Black-Scholes option pricing model with the following assumptions: 2019 Expected volatility 69 - 71% Expected term (years) 5.5 - 7.0 Risk free interest rate 1.4 - 2.7% Expected dividend yield 0% Exercise price $17.29 - 37.66 Given the Company’s common stock has not been trading for a sufficient period of time, the Company utilizes a collection of volatilities of peer companies to estimate the expected volatility of its common stock. The expected term is calculated utilizing the simplified method. The following table provides a summary of the incentive unit activity under the Incentive Plan. These amounts include incentive units granted to employees, directors and consultants. Units Weighted Average Fair Value Outstanding at December 31, 2017 3,669,963 $ 0.46 Granted 1,715,368 $ 4.54 Forfeited (34,982 ) $ 4.85 Cancelled (5,350,349 ) $ 1.86 Outstanding at December 31, 2018 — $ — The following table provides a summary of the restricted stock grant activity under the Incentive Plan in 2019. These amounts include restricted stock granted to employees, directors and consultants. Shares Weighted Average Grant Date Fair Value Per Share Unvested restricted stock at December 31, 2018 1,102,289 $ 16.00 Vested (475,730 ) $ 16.00 Forfeited (50,485 ) $ 16.00 Unvested restricted stock at December 31, 2019 576,074 $ 16.00 The following table provides a summary of the stock option activity under the 2018 Plan in 2019. These amounts include stock options granted to employees, directors and consultants. Options Weighted Average Fair Value Outstanding at December 31, 2018 2,273,024 $ 9.88 Granted 1,520,678 $ 13.28 Exercised (176,897 ) $ 9.59 Forfeited (184,607 ) $ 11.23 Outstanding at December 31, 2019 3,432,198 $ 11.32 Exercisable at December 31, 2019 989,465 $ 9.93 Included in the stock options granted in the table above are options to purchase 1,995,660 shares of common stock that were granted to employees, directors, and consultants granted at the time of the incentive unit conversion that have the same vesting terms as the profit units that were outstanding in September 2018 before the profit interests were converted into common stock. At the time of issuance of the stock options, 357,658 stock options to purchase shares of common stock became immediately vested, resulting in stock compensation expense of $3,627,507. The following table provides a summary of the restricted stock unit activity under the 2018 Plan in 2019. These amounts include restricted stock units granted to employees. Shares Weighted Average Grant Date Fair Value Per Share Unvested restricted stock units at December 31, 2018 — $ — Granted 192,882 $ 19.96 Forfeited (11,510 ) $ 19.36 Unvested restricted stock units at December 31, 2019 181,372 $ 20.00 At December 31, 2019, there were 448,906 restricted shares under the Incentive Plan, 3,103,251 stock options under the 2018 Plan, and 146,277 restricted stock units under the 2018 Plan that vested and are expected to vest.

Investment in Equity Method Inv

Investment in Equity Method Investee	12 Months Ended
	Dec. 31, 2019
Equity Method Investments And Joint Ventures [Abstract]
Investment in Equity Method Investee	12. Investment in Equity Method Investee In June 2019, the Company entered into an agreement to establish a joint venture (Commitment Agreement) with Bayer CropScience LP (Bayer LP) to research, develop and commercialize PROTAC targeted protein degraders for applications in the field of agriculture Pursuant to the terms of the Commitment Agreement, the Company made an in-kind intellectual property contribution to Oerth in the form of a license to certain of the Company’s proprietary technology. Bayer LP has made a $56.0 million total cash commitment to Oerth, $16.0 million of which Bayer LP has contributed to Oerth during the quarter ended September 30, 2019, and an in-kind intellectual property contribution. The Company and Bayer LP each hold an ownership interest in Oerth initially representing 50% of the ownership interests. A 15% ownership interest of Oerth is reserved for the future grant of incentive units to employees and service providers of Oerth. Under the Commitment Agreement, the Company has no obligation to provide any additional funding and the Company’s ownership interest will not be diluted from future contributions from Bayer LP. The Company has no exposure to future losses of Oerth. The activities of Oerth are controlled by a management board under the joint control of the Company and Bayer LP. As Oerth is jointly controlled by the Company and Bayer LP, the Company accounts for its 50% interest using the equity method of accounting. The Company determined that Oerth is a variable interest entity and, accordingly, the Company has evaluated the significant activities of Oerth under the variable interest entity model and concluded that the significant activities consist primarily of research and development activities and, as the Company does not have the sole power to direct such activities, the Company is not the primary beneficiary. The Company will also provide to Oerth compensated research and development services and administrative services through a separate agreement. The services rendered by the Company during 2019 were insignificant. The Company determined that the fair value of the equity interest it received in Oerth in exchange for the license contributed was $49.4 million. The fair value of Oerth was determined utilizing discounted cash flows based on reasonable estimates and assumptions of cash flows expected from Oerth. The Company recognized revenue of $24.7 million attributable to the license contributed to Oerth and eliminated the remaining $24.7 million which corresponds to the Company’s 50% ownership in Oerth. The Company determined that the amount that was eliminated represents intra-entity profit which should be deferred until realized by Oerth. The deferral will be recognized if and when Oerth recognizes revenue associated with the license. Until such time, the remaining $24.7 million of revenue is indefinitely deferred and excluded from the results of operations of the Company. The amount recognized as revenue was treated as such because the licensing of its technology in connection with the formation of a joint venture is part of the Company’s major ongoing or central operations, as evidenced by previous licensing agreements. Total operating expenses and net loss of Oerth in 2019 was $49.8 million, which included research and development expenses equal to $49.4 million for the fair value of the license acquired from Arvinas. The Company’s initial investment in Oerth was $49.4 million which represented the fair value of shares received in exchange for the contribution of the license. The elimination of the intra-entity profit component of the revenue resulted in a reduction in the balance of the investment in Oerth, bringing its initial carrying value of the investment to $24.7 million. During 2019, the Company recorded equity method losses of $24.7 million based on its proportionate share of ownership. After recognition of its proportionate share of Oerth’s losses for the period the carrying value of the investment as of December 31, 2019 is now $0.

Income Taxes

Income Taxes	12 Months Ended
	Dec. 31, 2019
Income Tax Disclosure [Abstract]
Income Taxes	13. Income Taxes The Company has had no income tax expense due to operating losses incurred for the years ended December 31, 2019 and 2018. The Company has also not recorded any income tax benefits for the net operating losses incurred in each period due to its uncertainty of realizing a benefit from those items. All of the Company’s losses before income taxes were generated in the United States. A reconciliation of the U.S. federal statutory income tax rate to the Company’s effective income tax rate for the years ended December 31, 2019 and 2018 is as follows: 2019 2018 Federal statutory rate 21.0 % 21.0 % Federal research tax credit 3.5 % 2.5 % Stock compensation (2.2 )% (3.3 )% Change in valuation allowance (22.0 )% (20.3 )% Other (0.3 )% 0.1 % 0.0 % 0.0 % Deferred income taxes represent the tax effect of transactions that are reported in different periods for financial and tax reporting purposes. Temporary differences and carryforwards that give rise to a significant portion of the deferred income tax benefits and liabilities are as follows at December 31, 2019 and 2018: 2019 2018 Deferred income tax assets: Loss carryforwards $ 21,733,983 $ 12,236,973 Deferred revenue 7,871,790 6,179,875 Tax credits 5,121,644 2,681,628 Stock compensation 3,580,768 1,084,096 Other 183,118 181,734 Total deferred income tax assets 38,491,303 22,364,306 Deferred income tax liabilities Other (35,011 ) (35,345 ) Property, equipment and leasehold improvements (1,293,932 ) (540,609 ) Total deferred income tax liabilities (1,328,943 ) (575,954 ) Less valuation allowance (37,162,360 ) (21,788,352 ) Net deferred income tax assets $ — $ — The Company has provided a valuation allowance against the full amount of the deferred tax assets since, in the opinion of management, based upon the history of losses of the Company, it is more likely than not that the benefits will not be realized. All or a portion of the remaining valuation allowance may be reduced in future years based on an assessment of earnings sufficient to utilize these potential tax benefits. The valuation allowance increased by $15.4 million in 2019 and $8.5 million in 2018 due to the increase in the net operating loss carryforwards, stock compensation expense and research and development tax credits. The Company had approximately $103.5 million and $58.3 million of federal net operating loss carryforwards as of December 31, 2019 and 2018, respectively. Federal net operating loss carryforwards as of December 31, 2017 expire at various dates through fiscal year 2037 and federal net operating losses incurred in 2018 and in future years may be carried forward indefinitely, but the deductibility of such carryforwards is limited to 80% of the Company’s taxable income in the year in which carryforwards are used. The Company believes the federal net operating losses are subject to an annual limitation as a result of changes in the Company’s ownership, as defined by Federal Internal Revenue Code Section 382, in November 2019. Notwithstanding the limitations, the Company expects the federal net operating losses to be fully available under Section 382 within the next two years. The Company had approximately $5.1 million and $2.7 million of federal tax credit carryforwards as of December 31, 2019 and 2018, respectively, which expire at various dates through fiscal year 2038. The Company estimates that its federal credits will not be subject to the Section 382 limitation by 2021 and the federal tax credits will be available to offset future federal income tax. The Company complies with the provisions of ASC 740 in accounting for its uncertain tax positions. ASC 740 addresses the determination of whether tax benefits claimed or expected to be claimed on a tax return should be recorded in the financial statements. Under ASC 740, the Company may recognize the tax benefit from an uncertain tax position only if it is more likely that not that the tax position will be sustained on examination by the taxing authorities, based on the technical merits of the position. The Company recognizes interest accrued related to unrecognized tax benefits and penalties in tax expense. The Company had no accruals for interest and penalties at December 31, 2019 and 2018. The Company is required to file income tax returns in the U.S. Federal jurisdiction, and in the States of Connecticut and Massachusetts. The Company is a state franchise taxpayer in Connecticut and Massachusetts due to the Company’s loss position. As a result, there is no state income tax provision included in the financial statements. The 2016 tax year forward remain subject to future examinations by the applicable taxing authorities. For the years ended December 31, 2019 and 2018, the Company recorded a benefit from expected cash refunds to be provided by the State of Connecticut, equal to 65% of research and development credits, of $1.4 million and $0.1 million, respectively, which is included in Other Income in the accompanying consolidated statement of operations and comprehensive loss, due to the Company being a state franchise taxpayer. The benefit results from the exchange of the state research and development tax credit carryforwards for cash refunds. At December 31, 2019 and 2018, the Company has recorded receivables of $1.4 million and $1.1 million, respectively, relating to research and development credits due to the Company.

Commitments and Contingencies

Commitments and Contingencies	12 Months Ended
	Dec. 31, 2019
Commitments And Contingencies Disclosure [Abstract]
Commitments and Contingencies	14. Commitments and Contingencies Consulting and Sponsored Research Agreement Commitments In July 2016, the Company entered into a Corporate Sponsored Research Agreement (SRA) with Yale University, which was amended in April 2018. The amended SRA extended the agreement until April 2021 and amended the scope of work. The amended SRA requires quarterly payments of $250,000 through the end of the agreement. The total payments made under the SRA for 2019 and 2018 were $1,000,000 and $851,161, respectively. The Company entered into a consulting agreement with its Chief Scientific Advisor in 2018, which extends into 2021, and requires monthly payments of $20,833. During the years ended December 31, 2019 and 2018, the Company paid $250,000 and $176,110, respectively, pursuant to this consulting agreement.

Net Loss Per Common Share

Net Loss Per Common Share	12 Months Ended
	Dec. 31, 2019
Earnings Per Share [Abstract]
Net Loss Per Common Share	15. Net Loss Per Common Share Basic and diluted loss per common share were calculated as follows: 2019 2018 Net loss $ (70,292,227 ) $ (41,480,466 ) Change in redemption value of preferred units - (198,366,756 ) Net loss attributable to common shares – basic and diluted $ (70,292,227 ) $ (239,847,222 ) Weighted average number of common shares outstanding, basic and diluted 32,927,697 9,422,799 Net loss per common share $ (2.13 ) $ (25.45 ) The Company’s potential dilutive securities have been excluded from the computation of diluted net loss per common share as the effect would be to reduce the net loss per common share. The following common share equivalents have been excluded from the calculations of diluted loss per common share because their inclusion would have been antidilutive. 2019 2018 Stock options 3,432,198 2,273,024 Restricted stock awards 576,074 1,102,289 Restricted stock units 181,372 - 4,189,644 3,375,313

Selected Quarterly Financial Da

Selected Quarterly Financial Data (Unaudited)	12 Months Ended
	Dec. 31, 2019
Quarterly Financial Data [Abstract]
Selected Quarterly Financial Data (Unaudited)	16. Selected Quarterly Financial Data (Unaudited) Selected quarterly financial data is as follows: Three months ended March 31, 2019 June 30, 2019 September 30, 2019 December 31, 2019 Revenue $ 4,016,489 $ 4,016,489 $ 30,050,227 $ 4,893,273 Operating expenses: Research and development 14,190,359 16,000,638 16,588,050 20,414,783 General and administrative 5,640,629 6,440,779 7,957,364 7,268,390 Total operating expenses 19,830,988 22,441,417 24,545,414 27,683,173 Loss from operations (15,814,499 ) (18,424,928 ) 5,504,813 (22,789,900 ) Other income (expenses) Other income, net 243,122 191,729 405,302 595,443 Interest income 1,190,523 1,091,331 1,112,415 1,162,991 Interest expense (23,638 ) (22,778 ) (22,903 ) (16,250 ) Total other income 1,410,007 1,260,282 1,494,814 1,742,184 Loss from equity method investment - - (24,675,000 ) - Net loss (14,404,492 ) (17,164,646 ) (17,675,373 ) (21,047,716 ) Change in redemption value of redeemable preferred units - - - - Net loss attributable to common shares $ (14,404,492 ) $ (17,164,646 ) $ (17,675,373 ) $ (21,047,716 ) Net loss per common share, basic and diluted $ (0.46 ) $ (0.55 ) $ (0.54 ) $ (0.56 ) Weighted average common shares outstanding, basic and diluted 31,325,516 31,440,051 32,740,486 37,338,484 Three months ended March 31, 2018 June 30, 2018 September 30, 2018 December 31, 2018 Revenue $ 4,108,596 $ 3,399,895 $ 3,375,264 $ 3,440,165 Operating expenses: Research and development 7,143,817 10,337,835 13,149,879 14,562,299 General and administrative 1,246,887 1,579,605 4,284,231 5,821,445 Total operating expenses 8,390,704 11,917,440 17,434,110 20,383,744 Loss from operations (4,282,108 ) (8,517,545 ) (14,058,846 ) (16,943,579 ) Other income (expenses) Other income, net 127,449 130,945 160,100 (315,764 ) Change in fair value of preferred unit warrant (196,295 ) 2,516 — — Interest income 211,237 539,413 523,338 1,196,113 Interest expense (10,669 ) (9,871 ) (12,264 ) (24,636 ) Total other income 131,722 663,003 671,174 855,713 Net loss (4,150,386 ) (7,854,542 ) (13,387,672 ) (16,087,866 ) Change in redemption value of redeemable preferred units (71,482,098 ) (14,834,049 ) (112,050,609 ) — Net loss attributable to common shares $ (75,632,484 ) $ (22,688,591 ) $ (125,438,281 ) $ (16,087,866 ) Net loss per common share, basic and diluted $ (39.86 ) $ (11.96 ) $ (62.38 ) $ (0.52 ) Weighted average common shares outstanding, basic and diluted 1,897,544 1,897,544 2,010,807 31,098,634

Summary of Significant Accoun_2

Summary of Significant Accounting Policies (Policies)	12 Months Ended
	Dec. 31, 2019
Accounting Policies [Abstract]
Principles of Consolidation	Principles of Consolidation The consolidated financial statements of the Company include the accounts of Arvinas, Inc. and its wholly owned subsidiaries. All intercompany transactions have been eliminated in consolidation.
Use of Estimates	Use of Estimates The preparation of the Company’s consolidated financial statements in conformity with accounting principles generally accepted in the United States requires management to make certain estimates and assumptions that affect the reported amounts and disclosures in the financial statements. While management believes that estimates and assumptions used in the preparation of the consolidated financial statements are appropriate, actual results could differ from those estimates. The most significant estimates are those used in determination of the Company’s revenue recognition, fair value of its common and preferred units, preferred unit warrant liability, incentive equity compensation, and fair value of its investment in a joint venture (Oerth).
Financial Instruments	Financial Instruments The Company’s principal financial instruments comprise cash, marketable securities, account receivable, accounts payable, accrued liabilities and long-term debt. The carrying value of all financial instruments approximates fair value.
Cash and Cash Equivalents	Cash and Cash Equivalents The Company classifies as cash and cash equivalents amounts on deposit in banks and cash invested temporarily in various instruments, primarily money market accounts, with original maturities of three months or less at time of purchase. The carrying amounts reported in the consolidated balance sheets represent the fair values of cash and cash equivalents.
Concentration of Credit Risk	Concentration of Credit Risk The Company maintains its cash in financial institution accounts that, at times during the year, may exceed federally insured limits. The cash balances in the financial institutions are insured by the Federal Deposit Insurance Corporation (FDIC) up to $250,000. Cash may also be maintained at commercial institutions that are not insured by the FDIC. For the year ended December 31, 2019, 57% of the Company’s revenue was attributable to a license contributed to a joint venture, Oerth Bio LLC (Oerth), and two collaborators represented 19% and 16% of total revenue. For the year ended December 31, 2018, two collaborators each represented over 45% of total revenue. One collaborator accounted for the entire account receivable balance at December 31, 2018.
Marketable Securities	Marketable Securities The Company classifies its marketable securities as available-for-sale securities, which are carried at their fair value based on the quoted market prices of the securities with unrealized gains and losses reported as accumulated other comprehensive loss, a separate component of members’ equity. Realized gains and losses on available-for-sale securities are included in net earnings in the period earned or incurred.
Property, Equipment, and Leasehold Improvements	Property, Equipment, and Leasehold Improvements Property and equipment are recorded at cost. Depreciation is calculated using the straight-line method over the estimated useful lives, which range from three years for office equipment to five years for laboratory equipment. Maintenance and repairs which do not extend the lives of the assets are charged directly to expense as incurred. Upon retirement or disposal, cost and related accumulated depreciation are removed from the related accounts, and any resulting gain or loss is recognized as a component of income or loss for the period. Leasehold improvements are recorded at cost and amortized using the straight-line method over the shorter of the lease term or the useful life of the asset.
Impairment of Long-Lived Assets	Impairment of Long-Lived Assets When indications of potential impairments are present, the Company evaluates the carrying value of long-lived assets. The Company adjusts the carrying value of the long-lived assets if the sum of undiscounted expected future cash flows is less than carrying value. No such impairments were recorded during 2019 or 2018.
Deferred Financing Costs	Deferred Financing Costs Deferred financing costs are being amortized over the term of the related debt.
Segment Information	Segment Information The Company manages its operations as a single segment for the purposes of assessing performance and making operating decisions. All of the Company’s tangible assets are held in the United States. To date, all of the Company’s revenue has been generated in the United States.
Revenue Recognition and Deferred Revenue	Revenue Recognition and Deferred Revenue Revenues from Contracts The Company recognizes revenue under Accounting Standards Codification (ASC) 606, Revenue from Contracts with Customers. The research collaboration and license agreements typically include contingent milestone payments related to specified preclinical and clinical development milestones and regulatory milestones. These milestone payments represent variable consideration to be included within the transaction price using the most likely amount method. The Company determined that the most likely amount to be recognized was zero, against which no constraint was applied. The Company will continue to assess the probability of significant reversals for any amounts that become likely to be realized prior to recognizing the variable consideration associated with these payments within the transaction price. Revenue is recognized ratably over the Company’s expected performance period under each respective arrangement. The Company makes its best estimate of the period over which the Company expects to fulfill the Company’s performance obligations, which includes access to technology through the license agreement and research activities. Given the uncertainties of these collaboration arrangements, significant judgment is required to determine the duration of the performance period. For the years ended December 31, 2019 and 2018, the transaction price allocated to the combined performance obligation identified under the agreements is recognized as revenue on a straight-line basis over the estimated performance period under each respective arrangement. Straight-line basis was considered the best measure of progress in which control of the combined obligation transfers to the customers, due to the contract containing license rights to technology, research and development services, and joint committee participation, which in totality are expected to occur ratably over the performance period. The Company’s contracts may also call for certain sales-based milestone and royalty payments upon successful commercialization of a target. The Company recognizes revenues from sales-based milestone and royalty payments at the later of a) the occurrence of the subsequent sale; or b) the performance obligation to which some or all of the sales-based milestone or royalty payments has been allocated has been satisfied (or partially satisfied). The Company anticipates recognizing these milestones and royalty payments if and when subsequent sales are generated by the customer from the use of the technology. To date, no revenue from these sales-based milestone and royalty payments has been recognized for any periods. Amounts received prior to satisfying the above revenue recognition criteria are recorded as a contract liability in the Company’s accompanying consolidated balance sheets. The Company also recognized revenue under ASC 606 from its contribution of a license to Oerth. See Note 12.
Equity Method Investments	Equity Method Investments The Company accounts for investments for which it does not have a controlling interest in accordance with ASC 323, Investments – Equity Method and Joint Ventures
Preferred Unit Warrants	Preferred Unit Warrants Preferred unit warrants issued in conjunction with debt financings were initially recorded at fair value, using a Black-Scholes option pricing model, with a corresponding discount recorded against the face value of the note and a liability. The discount was then accreted against the face value of the note over its remaining term as additional interest expense. The Company classified warrants to purchase shares of its Series A Redeemable Convertible Preferred Units (Series A Preferred Units) as a liability on its balance sheets as these warrants were free-standing financial instruments that were exercisable for contingently redeemable shares. The preferred unit warrants were recorded in long-term liabilities at fair value, estimated using the Black-Scholes option pricing model, and marked to market at each balance sheet date. The change in carrying value was reported as the change in fair value of warrant liability in the accompanying consolidated statements of operations. The outstanding warrants were exercised in July 2018 and no warrants were outstanding as of December 31, 2019 and 2018.
Income Taxes	Income Taxes Prior to the conversion to a C-corporation, Arvinas LLC was taxed under the provisions of Subchapter K—Partners and Partnerships of the Internal Revenue Code. Under those provisions, Arvinas LLC did not pay federal or state corporate income taxes on its taxable income. Instead, each member would include net operating income or loss for Arvinas LLC on its individual return. Arvinas LLC was converted to a C-corporation in 2018. Arvinas, Inc. and its wholly owned subsidiaries use the asset and liability method of accounting for income taxes, as set forth in ASC 740, Accounting for Income Taxes Management has evaluated the effect of ASC 740 guidance related to uncertain income tax positions and concluded that the Company has no significant uncertain income tax positions at December 31, 2019 and 2018.
Equity-based Compensation	Equity-based Compensation Prior to its IPO, the Company periodically granted incentive units to employees and non-employees, which generally vested over a four-year period. The incentive units represented a separate substantive class of equity with defined rights within the LLC Operating Agreement. The incentive units represented profits interests in the Company, which was an interest in the increase in the value of the entity over the Participation Threshold, as defined in the LLC Operating Agreement and as determined at the time of grant. The holder, therefore, had the right to participate in distributions of profits only in excess of the Participation Threshold. The Participation Threshold was based on the valuation of the common unit on or around the grant date. The Company accounted for incentive units granted in accordance with ASC 718, Compensation-Stock Compensation The Company measures employee and board of director equity-based compensation for stock option and restricted stock grants based on the grant date fair value of the equity awards. Equity-based compensation expense is recognized over the requisite service period of the awards, net of estimated forfeitures. Estimated forfeitures are updated on a periodic basis based on actual experience. For equity awards that have a performance condition, the Company recognizes compensation expense based on its assessment of the probability that the performance condition will be achieved. The Company measures equity awards granted to consultants based on the fair value of the award on the date the award is granted. Compensation expense is recognized over the period during which services are rendered by such consultants until completed. The Company classifies equity-based compensation expense in its consolidated statement of operations in the same manner in which the award recipient’s salary and related costs are classified or in which the award recipient’s service payments are classified.
Research and Development	Research and Development Research and development costs are expensed as incurred. The Company records grants from governmental and non-profit agencies as a reduction in research and development expense. Grants are recognized when there is reasonable assurance that the Company will comply with the conditions attached to the grant arrangement and the grant will be received. Grant payments received related to research and development costs incurred prior to the approval of the qualifying program are recognized immediately upon approval of the program by the grantor.
Fair Value Measurements	Fair Value Measurements ASC Topic 820, Fair Value Measurements and Disclosures Financial Instruments Level 1—Inputs are based upon observable or quoted prices for identical instruments traded in active markets. Level 2—Inputs are based upon quoted prices for similar instruments in active markets, quoted prices for identical or similar instruments in markets that are not active, and model-based valuation techniques for which all significant assumptions are observable in the market or can be corroborated by observable market data for substantially the full term of the assets or liabilities. The Company’s Level 2 investments consist primarily of corporate notes and bonds and U.S. government and agency securities. Level 3—Inputs are generally unobservable and typically reflect management’s estimates of assumptions that market participants would use in pricing the asset or liability. The fair values are therefore determined using model-based techniques that include option pricing models, discounted cash flow models, and similar techniques. In determining fair value, the Company utilizes valuation techniques that maximize the use of observable inputs and minimize the use of unobservable inputs to the extent possible as well as considers counterparty credit risk in its assessment of fair value. The Company’s marketable securities consist of corporate bonds and government securities which are adjusted to fair value each balance sheet date, based on quoted prices, which are considered Level 2 inputs (see Note 5). During the year ended December 31, 2019, a non-recurring fair value measurement was applied to determine the fair value of the non-cash consideration of 50% equity ownership received related to Oerth. The fair value measurement was determined using an income approach based primarily on utilizing management’s estimates of future cash flows as inputs, which are considered Level 3 measurements within the above fair value hierarchy. The following tables summarize the fair values and levels within the fair value hierarchy in which the fair value measurements fall for assets and liabilities measured on a recurring basis as of: December 31, 2019 Description Level 1 Level 2 Level 3 Total Assets: Corporate bonds $ — $ 271,661,456 $ — $ 271,661,456 December 31, 2018 Description Level 1 Level 2 Level 3 Total Assets: Corporate bonds $ — $ 181,668,600 $ — $ 181,668,600 Government securities — 2,969,040 — 2,969,040 The following table presents the changes in Level 3 instruments, preferred unit warrant, measured on a recurring basis for the year ended December 31, 2018: Preferred Unit Warrant Balance at December 31, 2017 $ 50,888 Change in fair value 193,779 Exercise of warrant (244,667 ) Balance at December 31, 2018 $ — Fluctuation in the fair value of the Company’s Series A Preferred Units was the primary driver for the change in the Preferred Unit Warrant liability valuation during each year prior to its exercise. As the fair value of the Series A Preferred Units increase, the value to the holder of the instrument generally increases. Additionally, unit price volatility is one of the significant unobservable inputs used in the fair value measurement of the Company’s Preferred Unit Warrant liability. A decrease in expected volatility would generally result in a lower fair value measurement. The carrying value of accounts payable and accrued expenses approximate their fair value due to the short‑term nature of these assets and liabilities.
Net Loss per Common Share	Net Loss per Common Share Basic net loss per common share is computed by dividing net loss, after adjusting for redeemable preferred unit dividends, by the weighted-average number of common shares outstanding during the period. The change in current redemption value of the redeemable preferred units was treated as a deemed dividend for the period during 2018 prior to conversion to common units. Diluted net loss per share was computed using the weighted-average number of common shares outstanding during the period and, if dilutive, the weighted average number of potential shares of common shares. The effect of the conversion of redeemable preferred units into common units was excluded from the computation of diluted net loss per common share for all periods as their effect was antidilutive. Additionally, common share equivalents are excluded from the computation of diluted net loss per common share for all periods as their effect is antidilutive.
New Accounting Pronouncements	New Accounting Pronouncements Recently Adopted Accounting Pronouncements In February 2016, the Financial Accounting Standards Board (FASB) issued ASU No. 2016-02, Leases In June 2018, the FASB issued ASU No. 2018-07 , Improvements in Nonemployee Share-Based Payment Accounting Other accounting standards that have been issued by the FASB or other standards-setting bodies that do not require adoption until a future date are not expected to have a material impact on the Company’s financial statements upon adoption.

Summary of Significant Accoun_3

Summary of Significant Accounting Policies (Tables)	12 Months Ended
	Dec. 31, 2019
Accounting Policies [Abstract]
Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis	The following tables summarize the fair values and levels within the fair value hierarchy in which the fair value measurements fall for assets and liabilities measured on a recurring basis as of: December 31, 2019 Description Level 1 Level 2 Level 3 Total Assets: Corporate bonds $ — $ 271,661,456 $ — $ 271,661,456 December 31, 2018 Description Level 1 Level 2 Level 3 Total Assets: Corporate bonds $ — $ 181,668,600 $ — $ 181,668,600 Government securities — 2,969,040 — 2,969,040
Summary of Changes In Level 3 Instruments, Preferred Unit Warrant, Measured On Recurring Basis	The following table presents the changes in Level 3 instruments, preferred unit warrant, measured on a recurring basis for the year ended December 31, 2018: Preferred Unit Warrant Balance at December 31, 2017 $ 50,888 Change in fair value 193,779 Exercise of warrant (244,667 ) Balance at December 31, 2018 $ —

Research Collaboration and Li_2

Research Collaboration and License Agreements (Tables)	12 Months Ended
	Dec. 31, 2019
Research Collaboration And License Agreements [Abstract]
Summary of Contract Liabilities	Information about contract liabilities, included as deferred revenue in the accompanying Consolidated Balance Sheets, is as follows: 2019 2018 Contract liabilities $ 58,407,408 $ 53,550,671 Revenues recognized in the period from: Amounts included in deferred revenue in previous periods 14,335,188 13,553,136
Transaction Price Allocated to Performance Obligations	The aggregate amount of the transaction price allocated to performance obligations that are unsatisfied as of December 31, 2019 was $58.4 million, which is expected to be recognized as follows (in millions): 2020 $ 20.0 2021 19.7 2022 13.9 2023 4.8 $ 58.4

Marketable Securities (Tables)

Marketable Securities (Tables)	12 Months Ended
	Dec. 31, 2019
Investments Debt And Equity Securities [Abstract]
Summary of Company's Available for Sale Securities	The following is a summary of the Company’s available-for-sale securities as of December 31, 2019 and 2018. December 31, 2019 Description Effective Maturity Amortized Cost Gross Unrealized Gains Gross Unrealized Losses Fair Value Corporate bonds 2020 145,359,876 49,722 - 145,409,598 Corporate bonds 2021 126,194,004 57,854 - 126,251,858 Total $ 271,553,880 $ 107,576 $ - $ 271,661,456 December 31, 2018 Description Effective Maturity Amortized Cost Gross Unrealized Gains Gross Unrealized Losses Fair Value Corporate bonds 2019 $ 154,859,427 $ — $ (165,630 ) $ 154,693,797 Government bonds 2019 2,966,262 2,778 — 2,969,040 Corporate bonds 2020 27,029,673 (54,870 ) 26,974,803 Total $ 184,855,362 $ 2,778 $ (220,500 ) $ 184,637,640

Property, Equipment and Lease_2

Property, Equipment and Leasehold Improvements (Tables)	12 Months Ended
	Dec. 31, 2019
Property Plant And Equipment [Abstract]
Schedule of Property, Equipment and Leasehold Improvements	Property, equipment and leasehold improvements consist of the following at December 31: 2019 2018 Laboratory equipment $ 8,045,179 $ 3,757,265 Office equipment 865,888 577,418 Leasehold improvements 2,809,205 981,884 11,720,272 5,316,567 Less: accumulated depreciation (3,264,861 ) (1,733,531 ) Property, equipment and leasehold improvements, net $ 8,455,411 $ 3,583,036

Right to Use Assets and Liabi_2

Right to Use Assets and Liabilities (Tables)	12 Months Ended
	Dec. 31, 2019
Leases [Abstract]
Schedule of Maturities of Lease Liabilities	Maturities of lease liabilities for the years ending December 31 are: 2020 775,734 2021 912,465 2022 895,847 Total lease payments 2,584,046 Less: imputed interest (196,039 ) Total $ 2,388,007

Accrued Expenses (Tables)

Accrued Expenses (Tables)	12 Months Ended
	Dec. 31, 2019
Payables And Accruals [Abstract]
Components of Accrued Expenses	Accrued expenses consisted of the following at December 31: 2019 2018 Employee expenses $ 5,810,723 $ 2,795,205 Research and development expenses 1,186,935 357,148 Professional fees and other 605,246 848,923 $ 7,602,904 $ 4,001,276

Long-Term Debt (Tables)

Long-Term Debt (Tables)	12 Months Ended
	Dec. 31, 2019
Debt Disclosure [Abstract]
Schedule of Anticipated Future Minimum Payments on Long-Term Debt Excluding Discount on Debt	Anticipated future minimum payments on long-term debt for the years ending December 31 are: 2023 $ 92,480 2024 377,516 Beyond 5 years 1,530,004 Total $ 2,000,000

Equity (Tables)

Equity (Tables)	12 Months Ended
	Dec. 31, 2019
Schedule of Assumptions Used to Determine Fair Value of Incentive Common Units Granted	The fair value of the incentive units granted during the year ended December 31, 2018 was determined using the Black-Scholes option pricing model with the following assumptions: 2018 Expected volatility 66 - 71% Expected term (years) 5.6 - 6.1 Risk free interest rate 2.5 - 2.9% Expected dividend yield 0% Fair value of underlying common units $1.08 - 8.48
Schedule of Assumptions Used to Determine Fair Value of Stock Options Granted	The fair value of the stock options granted during the year ended December 31, 2019 was determined using the Black-Scholes option pricing model with the following assumptions: 2019 Expected volatility 69 - 71% Expected term (years) 5.5 - 7.0 Risk free interest rate 1.4 - 2.7% Expected dividend yield 0% Exercise price $17.29 - 37.66
Summary of Incentive Unit Activity	The following table provides a summary of the incentive unit activity under the Incentive Plan. These amounts include incentive units granted to employees, directors and consultants. Units Weighted Average Fair Value Outstanding at December 31, 2017 3,669,963 $ 0.46 Granted 1,715,368 $ 4.54 Forfeited (34,982 ) $ 4.85 Cancelled (5,350,349 ) $ 1.86 Outstanding at December 31, 2018 — $ —
Summary of Restricted Stock Grant Activity	The following table provides a summary of the restricted stock grant activity under the Incentive Plan in 2019. These amounts include restricted stock granted to employees, directors and consultants. Shares Weighted Average Grant Date Fair Value Per Share Unvested restricted stock at December 31, 2018 1,102,289 $ 16.00 Vested (475,730 ) $ 16.00 Forfeited (50,485 ) $ 16.00 Unvested restricted stock at December 31, 2019 576,074 $ 16.00
Summary of Stock Option Activity	The following table provides a summary of the stock option activity under the 2018 Plan in 2019. These amounts include stock options granted to employees, directors and consultants. Options Weighted Average Fair Value Outstanding at December 31, 2018 2,273,024 $ 9.88 Granted 1,520,678 $ 13.28 Exercised (176,897 ) $ 9.59 Forfeited (184,607 ) $ 11.23 Outstanding at December 31, 2019 3,432,198 $ 11.32 Exercisable at December 31, 2019 989,465 $ 9.93
Restricted Stock Units
Summary of Restricted Stock Grant Activity	The following table provides a summary of the restricted stock unit activity under the 2018 Plan in 2019. These amounts include restricted stock units granted to employees. Shares Weighted Average Grant Date Fair Value Per Share Unvested restricted stock units at December 31, 2018 — $ — Granted 192,882 $ 19.96 Forfeited (11,510 ) $ 19.36 Unvested restricted stock units at December 31, 2019 181,372 $ 20.00

Income Taxes (Tables)

Income Taxes (Tables)	12 Months Ended
	Dec. 31, 2019
Income Tax Disclosure [Abstract]
Reconciliation of the U.S. Federal Statutory Income Tax Rate to Effective Income Tax Rate	A reconciliation of the U.S. federal statutory income tax rate to the Company’s effective income tax rate for the years ended December 31, 2019 and 2018 is as follows: 2019 2018 Federal statutory rate 21.0 % 21.0 % Federal research tax credit 3.5 % 2.5 % Stock compensation (2.2 )% (3.3 )% Change in valuation allowance (22.0 )% (20.3 )% Other (0.3 )% 0.1 % 0.0 % 0.0 %
Summary of Deferred Income Taxes	Temporary differences and carryforwards that give rise to a significant portion of the deferred income tax benefits and liabilities are as follows at December 31, 2019 and 2018: 2019 2018 Deferred income tax assets: Loss carryforwards $ 21,733,983 $ 12,236,973 Deferred revenue 7,871,790 6,179,875 Tax credits 5,121,644 2,681,628 Stock compensation 3,580,768 1,084,096 Other 183,118 181,734 Total deferred income tax assets 38,491,303 22,364,306 Deferred income tax liabilities Other (35,011 ) (35,345 ) Property, equipment and leasehold improvements (1,293,932 ) (540,609 ) Total deferred income tax liabilities (1,328,943 ) (575,954 ) Less valuation allowance (37,162,360 ) (21,788,352 ) Net deferred income tax assets $ — $ —

Net Loss Per Common Share (Tabl

Net Loss Per Common Share (Tables)	12 Months Ended
	Dec. 31, 2019
Earnings Per Share [Abstract]
Basic and Diluted Loss per Common Share	Basic and diluted loss per common share were calculated as follows: 2019 2018 Net loss $ (70,292,227 ) $ (41,480,466 ) Change in redemption value of preferred units - (198,366,756 ) Net loss attributable to common shares – basic and diluted $ (70,292,227 ) $ (239,847,222 ) Weighted average number of common shares outstanding, basic and diluted 32,927,697 9,422,799 Net loss per common share $ (2.13 ) $ (25.45 )
Common Share Equivalents Excluded from the Calculations of Diluted Loss Per Common Share	The following common share equivalents have been excluded from the calculations of diluted loss per common share because their inclusion would have been antidilutive. 2019 2018 Stock options 3,432,198 2,273,024 Restricted stock awards 576,074 1,102,289 Restricted stock units 181,372 - 4,189,644 3,375,313

Selected Quarterly Financial _2

Selected Quarterly Financial Data (Unaudited) (Tables)	12 Months Ended
	Dec. 31, 2019
Quarterly Financial Data [Abstract]
Schedule of Selected Quarterly Financial Data (Unaudited)	Selected quarterly financial data is as follows: Three months ended March 31, 2019 June 30, 2019 September 30, 2019 December 31, 2019 Revenue $ 4,016,489 $ 4,016,489 $ 30,050,227 $ 4,893,273 Operating expenses: Research and development 14,190,359 16,000,638 16,588,050 20,414,783 General and administrative 5,640,629 6,440,779 7,957,364 7,268,390 Total operating expenses 19,830,988 22,441,417 24,545,414 27,683,173 Loss from operations (15,814,499 ) (18,424,928 ) 5,504,813 (22,789,900 ) Other income (expenses) Other income, net 243,122 191,729 405,302 595,443 Interest income 1,190,523 1,091,331 1,112,415 1,162,991 Interest expense (23,638 ) (22,778 ) (22,903 ) (16,250 ) Total other income 1,410,007 1,260,282 1,494,814 1,742,184 Loss from equity method investment - - (24,675,000 ) - Net loss (14,404,492 ) (17,164,646 ) (17,675,373 ) (21,047,716 ) Change in redemption value of redeemable preferred units - - - - Net loss attributable to common shares $ (14,404,492 ) $ (17,164,646 ) $ (17,675,373 ) $ (21,047,716 ) Net loss per common share, basic and diluted $ (0.46 ) $ (0.55 ) $ (0.54 ) $ (0.56 ) Weighted average common shares outstanding, basic and diluted 31,325,516 31,440,051 32,740,486 37,338,484 Three months ended March 31, 2018 June 30, 2018 September 30, 2018 December 31, 2018 Revenue $ 4,108,596 $ 3,399,895 $ 3,375,264 $ 3,440,165 Operating expenses: Research and development 7,143,817 10,337,835 13,149,879 14,562,299 General and administrative 1,246,887 1,579,605 4,284,231 5,821,445 Total operating expenses 8,390,704 11,917,440 17,434,110 20,383,744 Loss from operations (4,282,108 ) (8,517,545 ) (14,058,846 ) (16,943,579 ) Other income (expenses) Other income, net 127,449 130,945 160,100 (315,764 ) Change in fair value of preferred unit warrant (196,295 ) 2,516 — — Interest income 211,237 539,413 523,338 1,196,113 Interest expense (10,669 ) (9,871 ) (12,264 ) (24,636 ) Total other income 131,722 663,003 671,174 855,713 Net loss (4,150,386 ) (7,854,542 ) (13,387,672 ) (16,087,866 ) Change in redemption value of redeemable preferred units (71,482,098 ) (14,834,049 ) (112,050,609 ) — Net loss attributable to common shares $ (75,632,484 ) $ (22,688,591 ) $ (125,438,281 ) $ (16,087,866 ) Net loss per common share, basic and diluted $ (39.86 ) $ (11.96 ) $ (62.38 ) $ (0.52 ) Weighted average common shares outstanding, basic and diluted 1,897,544 1,897,544 2,010,807 31,098,634

Nature of Business - Additional

Nature of Business - Additional Information (Details)	Oct. 01, 2018USD ($)$ / sharesshares	Nov. 30, 2019USD ($)$ / sharesshares	Oct. 31, 2018$ / sharesshares	Sep. 30, 2018	Dec. 31, 2019USD ($)Subsidiary	Dec. 31, 2018USD ($)
Nature Of Business [Line Items]
Number of wholly owned subsidiaries | Subsidiary					4
Reverse stock split, conversion ratio				3.25
Fees and expenses | $	$ 12,000,000				$ 597,131	$ 3,423,589
Preferred stock outstanding	0
Restricted Stock
Nature Of Business [Line Items]
Restricted shares issued	1,268,923
Common Stock
Nature Of Business [Line Items]
Reverse stock split, description					The Company’s Board of Managers approved a one-for-3.25 reverse stock split of its issued and outstanding shares of common units
Reverse stock split, conversion ratio	0.3077
Common shares issued	1,795,221
Gross proceeds from sale of shares in Initial public offering before fees and expenses | $	$ 123,200,000	$ 115,000,000
Common stock issued for conversion of convertible preferred stock	19,697,928
Common Stock | Initial Public Offering
Nature Of Business [Line Items]
Issuance of common stock, net of underwriters' discounts and issuance costs, Shares	7,500,000	5,227,273
Share price, issued and sold | $ / shares	$ 16	$ 22
Common Stock | Over-Allotment Option
Nature Of Business [Line Items]
Issuance of common stock, net of underwriters' discounts and issuance costs, Shares			200,482
Share price, issued and sold | $ / shares			$ 16

Summary of Significant Accoun_4

Summary of Significant Accounting Policies - Additional Information (Details) - USD ($)	12 Months Ended
	Dec. 31, 2019	Dec. 31, 2018	Jan. 01, 2019
Summary Of Significant Accounting Policies [Line Items]
Impairment of long lived assets	$ 0	$ 0
Non-cash interest expense	7,940	$ 5,605
Equity method investments	$ 0
Warrants outstanding	0	0
Incentive units vesting period	4 years
Right-of-use assets	$ 2,278,623
Lease liabilities	$ 2,388,007
ASU 2016-02
Summary Of Significant Accounting Policies [Line Items]
Right-of-use assets			$ 2,400,000
Lease liabilities			$ 2,400,000
Office Equipment
Summary Of Significant Accounting Policies [Line Items]
Property and equipment, estimated useful life	3 years
Laboratory Equipment
Summary Of Significant Accounting Policies [Line Items]
Property and equipment, estimated useful life	5 years
Oerth
Summary Of Significant Accounting Policies [Line Items]
Equity method investments	$ 0
Equity method investment ownership percentage	50.00%
Sales Revenue, Net | Customer Concentration Risk | Oerth
Summary Of Significant Accounting Policies [Line Items]
Concentration risk, percentage	57.00%
Minimum | Accounts Receivable | Customer Concentration Risk
Summary Of Significant Accounting Policies [Line Items]
Concentration risk, percentage	19.00%
Minimum | Sales Revenue, Net | Customer Concentration Risk
Summary Of Significant Accounting Policies [Line Items]
Concentration risk, percentage	16.00%
Maximum
Summary Of Significant Accounting Policies [Line Items]
Federal deposit insurance corporation premium expense		$ 250,000
Maximum | Accounts Receivable | Customer Concentration Risk
Summary Of Significant Accounting Policies [Line Items]
Concentration risk, percentage		45.00%
Maximum | Sales Revenue, Net | Customer Concentration Risk
Summary Of Significant Accounting Policies [Line Items]
Concentration risk, percentage		45.00%

Summary of Significant Accoun_5

Summary of Significant Accounting Policies - Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis (Details) - USD ($)	Dec. 31, 2019	Dec. 31, 2018
Assets:
Fair value measurements of assets	$ 271,661,456	$ 184,637,640
Fair Value, Measurements, Recurring | Corporate Bonds
Assets:
Fair value measurements of assets	271,661,456	181,668,600
Fair Value, Measurements, Recurring | Corporate Bonds | Level 2
Assets:
Fair value measurements of assets	$ 271,661,456	181,668,600
Fair Value, Measurements, Recurring | Government Securities
Assets:
Fair value measurements of assets		2,969,040
Fair Value, Measurements, Recurring | Government Securities | Level 2
Assets:
Fair value measurements of assets		$ 2,969,040

Summary of Significant Accoun_6

Summary of Significant Accounting Policies - Summary of Changes In Level 3 Instruments, Preferred Unit Warrant, Measured On Recurring Basis (Details) - Fair Value, Measurements, Recurring - Level 3 - Preferred Unit Warrant	12 Months Ended
	Dec. 31, 2018USD ($)
Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation [Line Items]
Balance at beginning of period	$ 50,888
Change in fair value	193,779
Exercise of warrant	$ (244,667)

License Agreements - Additional

License Agreements - Additional Information (Details) - USD ($)	1 Months Ended	12 Months Ended
	Jul. 31, 2013	Dec. 31, 2019	Dec. 31, 2018	Dec. 31, 2015
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Payment for license agreement		$ 150,000	$ 75,000
Minimum
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Annual payment for license		75,000
Yale University
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Non-refundable upfront payment	$ 149,511
Reimbursed patent costs		352,663	$ 216,093
Yale University | Minimum
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Royalty payment		200,000
Yale University | Maximum
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Royalty payment		$ 500,000
Payment for sublicense agreement				$ 750,000

Research Collaboration and Li_3

Research Collaboration and License Agreements - Additional Information (Details)	1 Months Ended	4 Months Ended	12 Months Ended
	Nov. 30, 2017USD ($)Target	Dec. 31, 2015USD ($)	Dec. 31, 2019USD ($)Contract	Dec. 31, 2018USD ($)	Dec. 31, 2022USD ($)	Jul. 31, 2019USD ($)
Research Collaboration And License Agreements [Line Items]
Changes in deferred revenue due to billings			$ 4,856,736	$ (8,548,090)
Revenue recognized on research collaboration and license agreements			18,300,000
Unsatisfied performance obligations expected to be recognized as revenue			58,400,000
Bayer Collaboration Agreement
Research Collaboration And License Agreements [Line Items]
Contract revenue receivable if milestones achieved or options for all targets exercised						$ 17,500,000
Bayer Collaboration Agreement | Research Funding Payments
Research Collaboration And License Agreements [Line Items]
Contract revenue receivable if milestones achieved or options for all targets exercised						1,500,000
Bayer Collaboration Agreement | Research Funding Payments | Scenario Forecast
Research Collaboration And License Agreements [Line Items]
Contract revenue receivable if milestones achieved or options for all targets exercised					$ 10,500,000
Bayer Collaboration Agreement | Development Milestone Payments | Maximum
Research Collaboration And License Agreements [Line Items]
Contract revenue receivable if milestones achieved or options for all targets exercised						197,500,000
Bayer Collaboration Agreement | Sales-based Milestone Payments | Maximum
Research Collaboration And License Agreements [Line Items]
Contract revenue receivable if milestones achieved or options for all targets exercised						$ 490,000,000
Bayer Collaboration Agreement | Stock Purchase Agreement
Research Collaboration And License Agreements [Line Items]
Fair value of the shares sold			2,900,000
Additional consideration received			$ 2,900,000
Number of contracts to be combined | Contract			2
Pfizer, Inc.
Research Collaboration And License Agreements [Line Items]
Upfront non-refundable payment and certain additional payments received			$ 28,000,000
Changes in deferred revenue due to billings			23,100,000
Pfizer, Inc. | Development Milestone Payments | Maximum
Research Collaboration And License Agreements [Line Items]
Contract revenue receivable if milestones achieved or options for all targets exercised			225,000,000
Pfizer, Inc. | Sales-based Milestone Payments | Maximum
Research Collaboration And License Agreements [Line Items]
Contract revenue receivable if milestones achieved or options for all targets exercised			550,000,000
Pfizer, Inc. | Option Payments | Maximum
Research Collaboration And License Agreements [Line Items]
Contract revenue receivable if milestones achieved or options for all targets exercised			37,500,000
Pfizer, Inc. | Option Exercised
Research Collaboration And License Agreements [Line Items]
Contract revenue receivable if milestones achieved or options for all targets exercised			2,500,000
Pfizer, Inc. | Substitution Target Payments
Research Collaboration And License Agreements [Line Items]
Contract revenue receivable if milestones achieved or options for all targets exercised			$ 1,200,000
Genentech, Inc. and F. Hoffman-La Roche Ltd.
Research Collaboration And License Agreements [Line Items]
Upfront non-refundable payment and certain additional payments received	$ 34,500,000	$ 11,000,000
Number of designated targets | Target	10
Increase in revenue previously recognized due to offsetting impacts in total transaction price and expected period of performance	$ 400,000
Genentech, Inc. and F. Hoffman-La Roche Ltd. | Development Milestone Payments | Maximum
Research Collaboration And License Agreements [Line Items]
Contract revenue receivable if milestones achieved or options for all targets exercised	44,000,000
Genentech, Inc. and F. Hoffman-La Roche Ltd. | Regulatory Milestone Payments
Research Collaboration And License Agreements [Line Items]
Contract revenue receivable if milestones achieved or options for all targets exercised	52,500,000
Genentech, Inc. and F. Hoffman-La Roche Ltd. | Commercial Milestones
Research Collaboration And License Agreements [Line Items]
Contract revenue receivable if milestones achieved or options for all targets exercised	$ 60,000,000

Research Collaboration and Li_4

Research Collaboration and License Agreements - Summary of Contract Liabilities (Details) - USD ($)	12 Months Ended
	Dec. 31, 2019	Dec. 31, 2018
Revenue From Contract With Customer [Abstract]
Contract liabilities	$ 58,407,408	$ 53,550,671
Amounts included in deferred revenue in previous periods	$ 14,335,188	$ 13,553,136

Research Collaboration and Li_5

Research Collaboration and License Agreements - Transaction Price Allocated to Performance Obligations (Details) $ in Millions	Dec. 31, 2019USD ($)
Revenue Remaining Performance Obligation Expected Timing Of Satisfaction [Line Items]
Revenue, remaining performance obligation	$ 58.4
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date: 2020-01-01
Revenue Remaining Performance Obligation Expected Timing Of Satisfaction [Line Items]
Revenue, remaining performance obligation	$ 20
Revenue, remaining performance obligation, expected timing of satisfaction, period	1 year
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date: 2021-01-01
Revenue Remaining Performance Obligation Expected Timing Of Satisfaction [Line Items]
Revenue, remaining performance obligation	$ 19.7
Revenue, remaining performance obligation, expected timing of satisfaction, period	1 year
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date: 2022-01-01
Revenue Remaining Performance Obligation Expected Timing Of Satisfaction [Line Items]
Revenue, remaining performance obligation	$ 13.9
Revenue, remaining performance obligation, expected timing of satisfaction, period	1 year
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date: 2023-01-01
Revenue Remaining Performance Obligation Expected Timing Of Satisfaction [Line Items]
Revenue, remaining performance obligation	$ 4.8
Revenue, remaining performance obligation, expected timing of satisfaction, period	1 year

Research Collaboration and Li_6

Research Collaboration and License Agreements - Transaction Price Allocated to Performance Obligations (Details1) $ in Millions	Dec. 31, 2019USD ($)
Revenue From Contract With Customer [Abstract]
Revenue, remaining performance obligation	$ 58.4

Marketable Securities - Summary

Marketable Securities - Summary of Company's Available for Sale Securities (Details) - USD ($)	12 Months Ended
	Dec. 31, 2019	Dec. 31, 2018
Schedule Of Available For Sale Securities [Line Items]
Amortized Cost	$ 271,553,880	$ 184,855,362
Gross Unrealized Gains	107,576	2,778
Gross Unrealized Losses		(220,500)
Fair Value	$ 271,661,456	$ 184,637,640
Corporate Bonds | 2019
Schedule Of Available For Sale Securities [Line Items]
Effective Maturity		2019
Amortized Cost		$ 154,859,427
Gross Unrealized Losses		(165,630)
Fair Value		$ 154,693,797
Corporate Bonds | 2020
Schedule Of Available For Sale Securities [Line Items]
Effective Maturity	2020	2020
Amortized Cost	$ 145,359,876	$ 27,029,673
Gross Unrealized Gains	49,722
Gross Unrealized Losses		(54,870)
Fair Value	$ 145,409,598	$ 26,974,803
Corporate Bonds | 2021
Schedule Of Available For Sale Securities [Line Items]
Effective Maturity	2021
Amortized Cost	$ 126,194,004
Gross Unrealized Gains	57,854
Fair Value	$ 126,251,858
Government Bonds | 2019
Schedule Of Available For Sale Securities [Line Items]
Effective Maturity		2019
Amortized Cost		$ 2,966,262
Gross Unrealized Gains		2,778
Fair Value		$ 2,969,040

Property, Equipment and Lease_3

Property, Equipment and Leasehold Improvements - Schedule of Property, Equipment and Leasehold Improvements (Details) - USD ($)	Dec. 31, 2019	Dec. 31, 2018
Property Plant And Equipment [Line Items]
Property, equipment and leasehold improvements, gross	$ 11,720,272	$ 5,316,567
Less: accumulated depreciation	(3,264,861)	(1,733,531)
Property, equipment and leasehold improvements, net	8,455,411	3,583,036
Laboratory Equipment
Property Plant And Equipment [Line Items]
Property, equipment and leasehold improvements, gross	8,045,179	3,757,265
Office Equipment
Property Plant And Equipment [Line Items]
Property, equipment and leasehold improvements, gross	865,888	577,418
Leasehold Improvements
Property Plant And Equipment [Line Items]
Property, equipment and leasehold improvements, gross	$ 2,809,205	$ 981,884

Property, Equipment and Lease_4

Property, Equipment and Leasehold Improvements - Additional Information (Details) - USD ($)	12 Months Ended
	Dec. 31, 2019	Dec. 31, 2018
Property Plant And Equipment [Abstract]
Depreciation expense	$ 1,561,557	$ 706,000

Right to Use Assets and Liabi_3

Right to Use Assets and Liabilities - Additional Information (Details) - USD ($)	12 Months Ended
	Dec. 31, 2019	Dec. 31, 2018
Lessee Lease Description [Line Items]
Right of use assets obtained in exchange for lease liabilities	$ 571,885
Operating lease, existence of option to extend	true
Operating lease, existence of option to terminate	true
Operating lease, weighted average remaining lease term	2 years 10 months 24 days
Operating lease expiration date	Dec. 31, 2022
Operating lease cost	$ 817,057
Operating cash flows used for operating leases	$ 581,961
Future minimum annual lease payments, 2019		$ 705,606
Future minimum annual lease payments, 2020		731,541
Future minimum annual lease payments, 2021		731,541
Future minimum annual lease payments, 2022		716,906
Future minimum lease payments , Total		$ 2,885,594
Minimum
Lessee Lease Description [Line Items]
Percentage of incremental borrowing for lease Payments	5.10%
Maximum
Lessee Lease Description [Line Items]
Percentage of incremental borrowing for lease Payments	6.60%

Right to Use Assets and Liabi_4

Right to Use Assets and Liabilities - Schedule of Maturities of Lease Liabilities (Details)	Dec. 31, 2019USD ($)
Leases [Abstract]
2020	$ 775,734
2021	912,465
2022	895,847
Total lease payments	2,584,046
Less: imputed interest	(196,039)
Lease liabilities	$ 2,388,007

Accrued Expenses - Components o

Accrued Expenses - Components of Accrued Expenses (Details) - USD ($)	Dec. 31, 2019	Dec. 31, 2018
Payables And Accruals [Abstract]
Employee expenses	$ 5,810,723	$ 2,795,205
Research and development expenses	1,186,935	357,148
Professional fees and other	605,246	848,923
Accrued expenses	$ 7,602,904	$ 4,001,276

Long-Term Debt - Additional Inf

Long-Term Debt - Additional Information (Details) - USD ($)	1 Months Ended			12 Months Ended
	Sep. 30, 2018	Jun. 30, 2018	Aug. 31, 2013	Dec. 31, 2019	Dec. 31, 2018	Dec. 31, 2014	Jan. 01, 2015
Debt Instrument [Line Items]
Debt instrument, outstanding amount				$ 2,000,000
Total unamortized debt discount on Loan					$ 7,210
Amortization of debt discount				7,210	12,359
Interest expense, Debt				$ 85,569	57,440
2014 Assistance Agreement | State of Connecticut
Debt Instrument [Line Items]
Debt instrument maturity month and year						2024-01
Debt instrument face amount						$ 2,500,000
Percentage of liquidated damages						7.50%
2018 Assistance Agreement | State of Connecticut
Debt Instrument [Line Items]
Debt instrument, interest rate per annum	3.25%
Debt instrument maturity month and year	2028-06
Debt instrument face amount	$ 2,000,000
Percentage of liquidated damages	7.50%
Percentage of maximum funding on total project costs		50.00%
Debt instrument interest payments term	60 months
Debt instrument amortization period after interest payments period	120 months
2018 Assistance Agreement | State of Connecticut | Maximum
Debt Instrument [Line Items]
Debt instrument face amount		$ 2,000,000
Forgiveness of funding on achieving certain employment conditions	$ 1,000,000
Series A Preferred Unit Warrant
Debt Instrument [Line Items]
Warrant to purchase of stock			110,116
Warrant purchase price per share			$ 0.6811
Term of warrant from the date of issuance			7 years
Series A Redeemable Convertible Preferred Units
Debt Instrument [Line Items]
Warrant to purchase of stock							110,116
Loan Agreement | Connecticut Innovations, Inc. | Secured Debt
Debt Instrument [Line Items]
Debt instrument, maximum borrowing capacity			$ 750,000
Debt instrument, frequency of periodic payment				monthly
Debt instrument, interest rate per annum			7.50%
Debt instrument, interest only payment period upon first draw of funds			10 months
Debt instrument, date of first required payment			Jun. 1, 2015
Debt instrument, maturity date			Jul. 31, 2019
Debt instrument, outstanding amount					$ 169,610
Loan Agreement | Connecticut Innovations, Inc. | Secured Debt | Leasehold Improvements
Debt Instrument [Line Items]
Debt instrument, maximum borrowing capacity			$ 100,000

Long-Term Debt - Schedule of An

Long-Term Debt - Schedule of Anticipated Future Minimum Payments on Long-Term Debt Excluding Discount on Debt (Details)	Dec. 31, 2019USD ($)
Long Term Debt By Maturity [Abstract]
2023	$ 92,480
2024	377,516
Beyond 5 years	1,530,004
Total	$ 2,000,000

Members' Equity - Additional In

Members' Equity - Additional Information (Details)	1 Months Ended		12 Months Ended			24 Months Ended
	Sep. 30, 2018	Mar. 31, 2018USD ($)$ / sharesshares	Dec. 31, 2019USD ($)	Dec. 31, 2018USD ($)	Dec. 31, 2015USD ($)$ / sharesshares	Dec. 31, 2014USD ($)$ / sharesshares
Preferred stock issued, value			$ 137,088,875	$ 111,159,583
Reverse stock split, conversion ratio	3.25
Series A Redeemable Convertible Preferred Stock
Preferred stock issued, shares | shares						22,463,665
Preferred stock issued, value						$ 15,300,000
Stock issued, price per share/unit | $ / shares						$ 0.6811
Series B Redeemable Convertible Preferred Units
Preferred stock issued, shares | shares					24,977,489
Preferred stock issued, value					$ 41,600,000
Stock issued, price per share/unit | $ / shares					$ 1.6659
Series C Redeemable Convertible Preferred Units
Preferred stock issued, shares | shares		16,467,066
Preferred stock issued, value		$ 55,000,000
Stock issued, price per share/unit | $ / shares		$ 3.34
Common Units
Common stock, voting rights			one

Equity - Additional Information

Equity - Additional Information (Details) - USD ($)	Oct. 01, 2018	Nov. 30, 2019	Jul. 31, 2019	Sep. 30, 2018	Mar. 31, 2018	Dec. 31, 2018	Dec. 31, 2019	Dec. 31, 2018
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share-based award, vesting period							4 years
Share-based award, stock options granted				1,995,660
Stock options vested				357,658
Stock Options
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Compensation expense				$ 3,627,507
Common Shares
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Gross proceeds from sale of shares in Initial public offering before fees and expenses	$ 123,200,000	$ 115,000,000
Fees and expenses		$ 7,400,000
Common Shares | Initial Public Offering
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Stock Issued During Period, Shares, New Issues	7,500,000	5,227,273
Share price, issued and sold	$ 16	$ 22
Bayer A G
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Stock Issued During Period, Shares, New Issues			1,346,313
Common stock issued in period			$ 32,500,000
Average common stock preceding days			60 days
Prior to stock purchase agreement premium			15.00%
Expiration period			6 months
Incentive Plan
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Incentive units authorized for issuance					6,199,477
Share-based award, expiration date					Sep. 30, 2018
Incentive units authorized for issuance							1,293,510
Share-based award, non-option equity instruments granted								1,715,368
Share-based award, stock options granted				1,744,650			1,468,983
Weighted average fair value of stock options granted							$ 13.28
Incentive Plan | Employee
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Compensation expense							$ 18,660,743	$ 10,026,666
Compensation expense not yet recognized							$ 15,484,188
Compensation expense not yet recognized, period of recognition							1 year 7 months 6 days
Incentive Plan | Consultants
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share-based award, stock options granted				251,010
Compensation expense							$ 1,411,967
Compensation expense not yet recognized							$ 895,816
Incentive Plan | Restricted Stock
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share-based award, non-option equity instruments granted				1,253,263
Restricted shares vested and expected to vest							448,906
Incentive Plan | Restricted Stock | Consultants
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share-based award, non-option equity instruments granted				11,097
Incentive Plan | Restricted Stock Units
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share-based award, non-option equity instruments granted							192,882
Incentive Plan | Restricted Stock Units | Employee
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share-based award, non-option equity instruments granted							192,882
Incentive Plan | Stock Options
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share-based award, requisite service period							4 years
Share-based award, maximum contractual term							10 years
Incentive Plan | Incentive Units | Consultants
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share-based award, stock options granted							51,695
Incentive Plan | Minimum
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share-based award, vesting period					1 year
Incentive Plan | Maximum
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share-based award, vesting period					4 years
Available for issuance of common stock				1,277,181
Incentive Plan | Maximum | Consultants
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Compensation expense not yet recognized, period of recognition							1 year 3 months 18 days
2018 Plan
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Available for issuance of common stock				4,067,007
Annual increase in reserved shares as percentage of outstanding common stock				4.00%
Share-based award, stock options granted						286,307	1,520,678
Weighted average fair value of stock options granted							$ 13.28
Stock options vested							989,465
Stock options vested and expected to vest							3,103,251
Restricted stock units vested and expected to vest							146,277
2018 Plan | Consultants
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share-based award, stock options granted							10,000
2018 Plan | Minimum
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Annual increase in reserved shares of common stock				4,989,593

Equity - Schedule of Assumption

Equity - Schedule of Assumptions Used to Determine Fair Value of Incentive Common Units Granted (Details) - Incentive Common Units	12 Months Ended
	Dec. 31, 2018$ / shares
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Expected volatility, minimum	66.00%
Expected volatility, maximum	71.00%
Risk free interest rate, minimum	2.50%
Risk free interest rate, maximum	2.90%
Expected dividend yield	0.00%
Minimum
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Expected term (years)	5 years 7 months 6 days
Fair value of underlying common units	$ 1.08
Maximum
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Expected term (years)	6 years 1 month 6 days
Fair value of underlying common units	$ 8.48

Equity - Schedule of Assumpti_2

Equity - Schedule of Assumptions Used to Determine Fair Value of and Stock Options Granted (Details) - Stock Options	12 Months Ended
	Dec. 31, 2019$ / shares
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Expected volatility, minimum	69.00%
Expected volatility, maximum	71.00%
Risk free interest rate, minimum	1.40%
Risk free interest rate, maximum	2.70%
Expected dividend yield	0.00%
Minimum
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Expected term (years)	5 years 6 months
Fair value of underlying common units	$ 17.29
Maximum
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Expected term (years)	7 years
Fair value of underlying common units	$ 37.66

Equity - Summary of Incentive U

Equity - Summary of Incentive Unit Activity (Details) - Incentive Plan	12 Months Ended
	Dec. 31, 2018$ / sharesshares
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Incentive Units, Granted	1,715,368
Incentive Units | Employees, Directors and Consultants
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Incentive Units, Outstanding, Beginning Balance	3,669,963
Incentive Units, Granted	1,715,368
Incentive Units, Forfeited	(34,982)
Incentive Units, Cancelled	(5,350,349)
Incentive Units, Outstanding, Ending Balance	0
Weighted Average Fair Value, Outstanding, Beginning Balance | $ / shares	$ 0.46
Weighted Average Fair Value, Granted | $ / shares	4.54
Weighted Average Fair Value, Forfeited | $ / shares	4.85
Weighted Average Fair Value, Cancelled | $ / shares	1.86
Weighted Average Fair Value, Outstanding, Ending Balance | $ / shares	$ 0

Equity - Summary of Restricted

Equity - Summary of Restricted Stock Grant Activity (Details) - Incentive Plan - $ / shares	1 Months Ended	12 Months Ended
	Sep. 30, 2018	Dec. 31, 2019	Dec. 31, 2018
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Restricted Shares, Granted			1,715,368
Restricted Stock
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Restricted Shares, Granted	1,253,263
Restricted Stock | Employees, Directors and Consultants
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Unvested Restricted Stock, Shares, Beginning Balance		1,102,289
Restricted Shares, Vested		(475,730)
Restricted Shares, Forfeited		(50,485)
Unvested Restricted Stock, Shares, Ending Balance		576,074	1,102,289
Weighted Average Fair Value, Outstanding, Beginning Balance		$ 16
Weighted Average Grant Date Fair Value Per Share, Vested		16
Weighted Average Grant Date Fair Value Per Share, Forfeited		16
Weighted Average Fair Value, Outstanding, Ending Balance		$ 16	$ 16
Restricted Stock Units
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Restricted Shares, Granted		192,882
Restricted Stock Units | Employees
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Unvested Restricted Stock, Shares, Beginning Balance		0
Restricted Shares, Granted		192,882
Restricted Shares, Forfeited		(11,510)
Unvested Restricted Stock, Shares, Ending Balance		181,372	0
Weighted Average Fair Value, Outstanding, Beginning Balance		$ 0
Weighted Average Grant Date Fair Value Per Share, Granted		19.96
Weighted Average Grant Date Fair Value Per Share, Forfeited		19.36
Weighted Average Fair Value, Outstanding, Ending Balance		$ 20	$ 0

Equity - Summary of Stock Optio

Equity - Summary of Stock Option Activity (Details) - $ / shares	1 Months Ended	3 Months Ended	12 Months Ended
	Sep. 30, 2018	Dec. 31, 2018	Dec. 31, 2019
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Options, Granted	1,995,660
Options, Exercisable, Ending Balance	357,658
2018 Plan
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Options, Outstanding, Beginning Balance			2,273,024
Options, Granted		286,307	1,520,678
Options, Exercised			(176,897)
Options, Forfeited			(184,607)
Options, Outstanding, Ending Balance		2,273,024	3,432,198
Options, Exercisable, Ending Balance			989,465
Weighted Average Fair Value, Outstanding, Beginning Balance			$ 9.88
Weighted Average Fair Value, Granted			13.28
Weighted Average Fair Value, Exercised			9.59
Weighted Average Fair Value, Forfeited			11.23
Weighted Average Fair Value, Outstanding, Ending Balance		$ 9.88	11.32
Weighted Average Fair Value, Exercisable, Ending Balance			$ 9.93

Investment in Equity Method I_2

Investment in Equity Method Investee - Additional Information (Details) - USD ($)	3 Months Ended	12 Months Ended
	Sep. 30, 2019	Dec. 31, 2019	Dec. 31, 2018
Schedule Of Equity Method Investments [Line Items]
Revenue recognized		$ 14,335,188	$ 13,553,136
Deferred revenue		58,407,408	53,550,671
Loss from equity method investment	$ (24,675,000)	(24,675,000)	$ 0
Equity method investments		0
Oerth
Schedule Of Equity Method Investments [Line Items]
Cash commitment		$ 49,400,000
Ownership interest in joint venture		50.00%
Future grant of incentive units to service providers, percentage		15.00%
Revenue recognized		$ 24,700,000
Deferred revenue		24,700,000
Operating expenses		49,800,000
Net loss		49,800,000
Research and development expenses		49,400,000
Loss from equity method investment		24,700,000
Equity method investments		0
Bayer LP | Oerth
Schedule Of Equity Method Investments [Line Items]
Cash commitment		56,000,000
Contributed to joint venture entity		$ 16,000,000
Ownership interest in joint venture		50.00%

Income Taxes - Additional Infor

Income Taxes - Additional Information (Detail) - USD ($)	12 Months Ended
	Dec. 31, 2019	Dec. 31, 2018	Dec. 31, 2016
Income Tax Disclosure [Line Items]
Income tax expense (benefit)	$ 0	$ 0
Unrecognized tax benefits, income tax penalties and interest accrued	$ 0	$ 0
Effective income tax rate reconciliation, tax credit, research and development, percent	3.50%	2.50%
Effective income tax rate reconciliation, tax credit, research and development, amount	$ 1,400,000	$ 100,000
Federal
Income Tax Disclosure [Line Items]
Net operating loss carryforwards	$ 103,500,000	$ 58,300,000
Net operating loss carryforwards, expiration year	2037	2037
Operating losses carry forward, maximum deductibility percentage	80.00%
Net operating loss carryforwards, limitations on use	The Company believes the federal net operating losses are subject to an annual limitation as a result of changes in the Company’s ownership, as defined by Federal Internal Revenue Code Section 382, in November 2019. Notwithstanding the limitations, the Company expects the federal net operating losses to be fully available under Section 382 within the next two years.
Tax credit carryforwards	$ 5,100,000	$ 2,700,000
Tax credit carryforwards, expiration year	2038	2038
Income tax examination year			2016
State
Income Tax Disclosure [Line Items]
Income tax expense (benefit)	$ 0
Research and Development Tax Credits
Income Tax Disclosure [Line Items]
Increase in valuation allowance	$ 15,400,000	$ 8,500,000
Effective income tax rate reconciliation, tax credit, research and development, percent	65.00%	65.00%
Income taxes receivable	$ 1,400,000	$ 1,100,000

Income Taxes - Reconciliation o

Income Taxes - Reconciliation of the U.S. Federal Statutory Income Tax Rate to Effective Income Tax Rate (Details)	12 Months Ended
	Dec. 31, 2019	Dec. 31, 2018
Income Tax Disclosure [Abstract]
Federal statutory rate	21.00%	21.00%
Federal research tax credit	3.50%	2.50%
Stock compensation	(2.20%)	(3.30%)
Change in valuation allowance	(22.00%)	(20.30%)
Other	(0.30%)	0.10%
Reconciliation of effective income tax rate	0.00%	0.00%

Income Taxes - Summary of Defer

Income Taxes - Summary of Deferred Income Taxes (Details) - USD ($)	Dec. 31, 2019	Dec. 31, 2018
Deferred income tax assets:
Loss carryforwards	$ 21,733,983	$ 12,236,973
Deferred revenue	7,871,790	6,179,875
Tax credits	5,121,644	2,681,628
Stock compensation	3,580,768	1,084,096
Other	183,118	181,734
Total deferred income tax assets	38,491,303	22,364,306
Deferred income tax liabilities
Other	(35,011)	(35,345)
Property, equipment and leasehold improvements	(1,293,932)	(540,609)
Total deferred income tax liabilities	(1,328,943)	(575,954)
Less valuation allowance	$ (37,162,360)	(21,788,352)
Net deferred income tax assets		$ 0

Commitments and Contingencies -

Commitments and Contingencies - Additional Information (Details) - USD ($)	12 Months Ended
	Dec. 31, 2019	Dec. 31, 2018
Consulting Agreement
Commitments And Contingencies [Line Items]
Payment for consulting service	$ 250,000	$ 176,110
Monthly research payments	20,833
Yale University | Amended Corporate Sponsored Research Agreement
Commitments And Contingencies [Line Items]
Quarterly research payments	250,000
Yale University | Corporate Sponsored Research Agreement (SRA)
Commitments And Contingencies [Line Items]
Total research payments	$ 1,000,000	$ 851,161
Related party agreement, description	In July 2016, the Company entered into a Corporate Sponsored Research Agreement (SRA) with Yale University, which was amended in April 2018. The amended SRA extended the agreement until April 2021 and amended the scope of work. The amended SRA requires quarterly payments of $250,000 through the end of the agreement. The total payments made under the SRA for 2019 and 2018 were $1,000,000 and $851,161, respectively.

Net Loss Per Common Share - Bas

Net Loss Per Common Share - Basic and Diluted Loss per Common Share (Details) - USD ($)	3 Months Ended								12 Months Ended
	Dec. 31, 2019	Sep. 30, 2019	Jun. 30, 2019	Mar. 31, 2019	Dec. 31, 2018	Sep. 30, 2018	Jun. 30, 2018	Mar. 31, 2018	Dec. 31, 2019	Dec. 31, 2018
Earnings Per Share [Abstract]
Net loss	$ (21,047,716)	$ (17,675,373)	$ (17,164,646)	$ (14,404,492)	$ (16,087,866)	$ (13,387,672)	$ (7,854,542)	$ (4,150,386)	$ (70,292,227)	$ (41,480,466)
Change in redemption value of preferred units						$ (112,050,609)	$ (14,834,049)	$ (71,482,098)	0	(198,366,756)
Net loss attributable to common shares – basic and diluted									$ (70,292,227)	$ (239,847,222)
Weighted average number of common shares outstanding, basic and diluted	37,338,484	32,740,486	31,440,051	31,325,516	31,098,634	2,010,807	1,897,544	1,897,544	32,927,697	9,422,799
Net loss per common share	$ (0.56)	$ (0.54)	$ (0.55)	$ (0.46)	$ (0.52)	$ (62.38)	$ (11.96)	$ (39.86)	$ (2.13)	$ (25.45)

Net Loss Per Common Share - Com

Net Loss Per Common Share - Common Share Equivalents Excluded from the Calculations of Diluted Loss Per Common Share (Details) - shares	12 Months Ended
	Dec. 31, 2019	Dec. 31, 2018
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Common share/unit equivalents excluded from the calculations of diluted loss per common share	4,189,644	3,375,313
Stock Options
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Common share/unit equivalents excluded from the calculations of diluted loss per common share	3,432,198	2,273,024
Restricted Stock
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Common share/unit equivalents excluded from the calculations of diluted loss per common share	576,074	1,102,289
Restricted Stock Units
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Common share/unit equivalents excluded from the calculations of diluted loss per common share	181,372

Selected Quarterly Financial _3

Selected Quarterly Financial Data (Unaudited) (Details) - USD ($)	3 Months Ended								12 Months Ended
	Dec. 31, 2019	Sep. 30, 2019	Jun. 30, 2019	Mar. 31, 2019	Dec. 31, 2018	Sep. 30, 2018	Jun. 30, 2018	Mar. 31, 2018	Dec. 31, 2019	Dec. 31, 2018
Selected Quarterly Financial Information [Abstract]
Revenue	$ 4,893,273	$ 30,050,227	$ 4,016,489	$ 4,016,489	$ 3,440,165	$ 3,375,264	$ 3,399,895	$ 4,108,596	$ 42,976,478	$ 14,323,920
Operating expenses:
Research and development	20,414,783	16,588,050	16,000,638	14,190,359	14,562,299	13,149,879	10,337,835	7,143,817	67,193,830	45,193,830
General and administrative	7,268,390	7,957,364	6,440,779	5,640,629	5,821,445	4,284,231	1,579,605	1,246,887	27,307,162	12,932,168
Total operating expenses	27,683,173	24,545,414	22,441,417	19,830,988	20,383,744	17,434,110	11,917,440	8,390,704	94,500,992	58,125,998
Loss from operations	(22,789,900)	5,504,813	(18,424,928)	(15,814,499)	(16,943,579)	(14,058,846)	(8,517,545)	(4,282,108)	(51,524,514)	(43,802,078)
Other income (expenses)
Other income, net	595,443	405,302	191,729	243,122	(315,764)	160,100	130,945	127,449
Change in fair value of preferred unit warrant							2,516	(196,295)	0	(193,779)
Interest income	1,162,991	1,112,415	1,091,331	1,190,523	1,196,113	523,338	539,413	211,237	4,557,260	2,470,101
Interest expense	(16,250)	(22,903)	(22,778)	(23,638)	(24,636)	(12,264)	(9,871)	(10,669)	(85,569)	(57,440)
Total other income	1,742,184	1,494,814	1,260,282	1,410,007	855,713	671,174	663,003	131,722	5,907,287	2,321,612
Loss from equity method investment		(24,675,000)							(24,675,000)	0
Net loss	(21,047,716)	(17,675,373)	(17,164,646)	(14,404,492)	(16,087,866)	(13,387,672)	(7,854,542)	(4,150,386)	(70,292,227)	(41,480,466)
Change in redemption value of redeemable preferred units						(112,050,609)	(14,834,049)	(71,482,098)	0	(198,366,756)
Net loss attributable to common shares	$ (21,047,716)	$ (17,675,373)	$ (17,164,646)	$ (14,404,492)	$ (16,087,866)	$ (125,438,281)	$ (22,688,591)	$ (75,632,484)	$ (70,292,227)	$ (239,847,222)
Net loss per common share, basic and diluted	$ (0.56)	$ (0.54)	$ (0.55)	$ (0.46)	$ (0.52)	$ (62.38)	$ (11.96)	$ (39.86)	$ (2.13)	$ (25.45)
Weighted average common shares outstanding, basic and diluted	37,338,484	32,740,486	31,440,051	31,325,516	31,098,634	2,010,807	1,897,544	1,897,544	32,927,697	9,422,799