Exhibit 5.1
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Sienna Biopharmaceuticals, Inc.
30699 Russell Ranch Road, Suite 140
Westlake Village, CA 91362
| Re: | Registration Statement on FormS-8; 1,058,855 shares of Common Stock of Sienna Biopharmaceuticals, Inc., par value $0.0001 per share |
Ladies and Gentlemen:
We have acted as special counsel to Sienna Biopharmaceuticals, Inc., a Delaware corporation (the “Company”), in connection with the registration by the Company of up to an aggregate of 1,058,855 shares of common stock of the Company, par value $0.0001 per share (the “Shares”), issuable under the Company’s 2017 Incentive Award Plan (the “2017 Plan”) and 2017 Employee Stock Purchase Plan (the “ESPP” and, together with the 2017 Plan, the “Plans”). The Shares are included in a registration statement on FormS-8 under the Securities Act of 1933, as amended (the “Act”), filed with the Securities and Exchange Commission (the “Commission”) on March 14, 2019 (the “Registration Statement”). This opinion is being furnished in connection with the requirements of Item 601(b)(5) of RegulationS-K under the Act, and no opinion is expressed herein as to any matter pertaining to the contents of the Registration Statement or the related prospectus, other than as expressly stated herein with respect to the issuance of the Shares.
As such counsel, we have examined such matters of fact and questions of law as we have considered appropriate for purposes of this letter. With your consent, we have relied upon certificates and other assurances of officers of the Company and others as to factual matters without having independently verified such factual matters. We are opining herein as to the General Corporation Law of the State of Delaware (the “DGCL”), and we express no opinion with respect to any other laws.
Subject to the foregoing and the other matters set forth herein, it is our opinion that, as of the date hereof, when the Shares shall have been duly registered on the books of the transfer agent and registrar therefor in the name or on behalf of the purchasers and have been issued by the Company against payment therefor in the circumstances contemplated by the Plans, assuming in