Exhibit 23.1
Consent of Independent Registered Public Accounting Firm
We consent to the reference to our firm under the caption “Experts” and to the use of our report dated December 11, 2020, in Amendment No. 1 to the Registration Statement (Form S-1 No. 333-252347) and related Prospectus of Decibel Therapeutics, Inc. dated January 28, 2021 for the registration of shares of its common stock.
| /s/ Ernst & Young LLP |
| Boston, Massachusetts |
| January 28, 2021 |
