Exhibit 99.3

Parkway Acquisition Corp. IMPORTANT ANNUAL MEETING INFORMATION 000004
ENDORSEMENT_LINE SACKPACK Using a black ink pen, mark your votes with an X as shown in this example. Please do not write outside the designated areas. MR A SAMPLE DESIGNATION (IF ANY) ADD 1 ADD 2 ADD 3 ADD 4 ADD 5 ADD 6 C123456789 000000000.000000 ext 000000000.000000 ext 000000000.000000 ext 000000000.000000 ext 000000000.000000 ext 000000000.000000 ext Electronic Voting Instructions Available 24 hours a day, 7 days a week! Instead of mailing your proxy, you may choose one of the voting methods outlined below to vote your proxy. VALIDATION DETAILS ARE LOCATED BELOW IN THE TITLE BAR. Proxies submitted by the Internet or telephone must be received by 12:00 a.m., EDT, on June 14, 2018. Vote by Internet • Go to www.investorvote.com/PKKW • Or scan the QR code with your smartphone • Follow the steps outlined on the secure website Vote by telephone • Call toll free 1-800-652-VOTE (8683) within the USA, US territories & Canada on a touch tone telephone • Follow the instructions provided by the recorded message Annual Meeting Proxy Card 1234 5678 9012 345 qIF YOU HAVE NOT VOTED VIA THE INTERNET OR TELEPHONE, FOLD ALONG THE PERFORATION, DETACH AND RETURN THE BOTTOM PORTION IN THE ENCLOSED ENVELOPE. A Proposals — The Board of Directors recommends a vote FOR each of the directors and 1, 3 and 4. For Against Abstain 1. To approve the agreement and plan of merger, dated as of March 1, 2018, by and among Parkway Acquisition Corp. (“Parkway”), Skyline National Bank (“Skyline”) and Great State Bank, pursuant to which Great State Bank will merge with and into Skyline, as more fully described in the accompanying joint proxy statement/prospectus. 2. To elect thirteen directors to serve for terms of one year each expiring at the 2019 annual meeting of shareholders: For Withhold 01 - Thomas M. Jackson, Jr 04 - Dr. J. Howard Conduff, Jr. 07 - T. Mauyer Gallimore 10 - Carl J. Richardson 13 - J. David Vaughan 02 - James W. Shortt 05 - Bryan L. Edwards 08 - R. Devereux Jarratt 11 - Melissa G. Rotenberry 03 - Jacky K. Anderson 06 - J. Allan Funk 09 - Theresa S. Lazo 12 - John Michael Turman For Against Abstain 3. To ratify the appointment of Elliott Davis, PLLC as Parkway’s independent registered public accounting firm for fiscal year ending December 31, 2018. 4. To adjourn the annual meeting to a later date or dates, if necessary to solicit additional proxies to approve Proposal 1. B Authorized Signatures — This section must be completed for your vote to be counted. — Date and Sign Below When shares are held by joint tenants, both should sign. Executors, administrators, trustees, etc. should give full title as such. If the signer is a corporation, please sign full corporate name by duly authorized officer. Date (mm/dd/yyyy) — Please print date below. Signature 1 — Please keep signature within the box. Signature 2 — Please keep signature within the box. IF VOTING BY MAIL, YOU MUST COMPLETE SECTIONS A - C ON BOTH SIDES OF THIS CARD. C 1234567890 J N T 1UPX 3784451 MR A SAMPLE (THIS AREA IS SET UP TO ACCOMMODATE 140 CHARACTERS) MR A SAMPLE AND MR A SAMPLE AND MR A SAMPLE AND MR A SAMPLE AND MR A SAMPLE AND MR A SAMPLE AND MR A SAMPLE AND MR A SAMPLE AND 02UI3C