Exhibit 99.16
FOURTH AMENDMENT TO PLEDGE AGREEMENT
THIS FOURTH AMENDMENT TO PLEDGE AGREEMENTis dated as of December 27, 2018 (this “Amendment”) and is made by and between SNBL U.S.A. Ltd., a Washington corporation (“SNBL USA”) and The Kagoshima Bank, Ltd. (“Lender”).
WHEREAS, on December 28, 2016, the Lender made one or more loans to Borrower (as defined in the Pledge Agreement referenced below) in an aggregate amount not to exceed Six Hundred Million Japanese Yen (¥600,000,000) (the “Prior Loan”), evidenced by that certain Loan Agreement dated as of December 28, 2016 made by Borrower and payable to the order of Lender (the “Original Loan Agreement”);
WHEREAS, on June 30, 2017, the Lender made one or more loans to Borrower (as defined in the Pledge Agreement referenced below) in an aggregate amount not to exceed Six Hundred Million Japanese Yen (¥600,000,000) (the “Second Prior Loan”), evidenced by that certain Loan Agreement dated as of June 30, 2017 made by Borrower and payable to the order of Lender (the “Second Prior Loan Agreement”); and
WHEREAS on December 27, 2017, the Lender made one or more loans to Borrower (as defined in the Pledge Agreement referenced below) in an aggregate amount not to exceed Six Hundred Million Japanese Yen (¥600,000,000) (the “Third Prior Loan”), evidenced by that certain Loan Agreement dated as of December 27, 2017 made by Borrower and payable to the order of Lender (the “Third Prior Loan Agreement”and collectively and severally with the Original Loan Agreement and the Second Prior Loan Agreement, the “Prior Loan Agreements”);
WHEREAS, on June 27, 2018, the Lender made one or more loans to Borrower (as defined in the Pledge Agreement referenced below) in an aggregate amount not to exceed Six Hundred Million Japanese Yen (¥600,000,000) (the “Existing Loan”), evidenced by that certain Loan Agreement dated as of June 27, 2018 made by Borrower and payable to the order of Lender (the “Existing Loan Agreement”);
WHEREAS, Lender and SNBL USA are party to a Stock Pledge Agreement dated December 28, 2016, pursuant to which SNBL USA pledged all of its shares of stock issued by WaVe Life Sciences Pte. Ltd., a Singapore company, and certain other collateral to Lender to secure the Prior Loan, as amended by that certain Amendment to Pledge Agreement dated as of June 30, 2017, and Second Amendment to Pledge Agreement dated as of December 27, 2017, and Third Amendment to Pledge Agreement, dated as of June 27, 2018, by and between SNBL USA and Lender (as so amended, the “Pledge Agreement”);
WHEREAS, it is contemplated that on or about the date hereof, the Existing Loan will be repaid in full and Lender intends to make a new loan to Borrower in the principal amount of Six Hundred Million Japanese Yen (¥600,000,000) (the “New Loan” and collectively with the Prior Loan, the Second Prior Loan, the Third Prior Loan and the Existing Loan, the “Loans”) and the parties hereto intend that the Collateral (as defined in the Pledge Agreement) secure the payment and performance of the New Loan; and
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