Exhibit 23.1
Consent of Independent Registered Public Accounting Firm
We consent to the incorporation by reference in the following Registration Statements:
| (1) | Registration Statement (Form S-8 No. 333-213108) pertaining to Converted Equity Awards Incentive Plan and 2016 Stock Incentive Plan of Aptevo Therapeutics Inc., |
| (2) | Registration Statement (Form S-8 No. 333-219875) pertaining to the 2016 Stock Incentive Plan of Aptevo Therapeutics Inc., |
| (3) | Registration Statement (Form S-8 No. 333-226717) pertaining to the 2018 Stock Incentive Plan of Aptevo Therapeutics Inc., |
| (4) | Registration Statement (Form S-3 No. 333-221499) of Aptevo Therapeutics Inc., and |
| (5) | Registration Statement (Form S-3 No. 333-229115) of Aptevo Therapeutics Inc.; |
of our report dated March 18, 2019, with respect to the consolidated financial statements of Aptevo Therapeutics Inc. included in this Annual Report (Form 10-K) of Aptevo Therapeutics Inc. for the year ended December 31, 2018.
/s/ Ernst & Young LLP
Seattle, Washington
March 18, 2019