Bellevue (BLVGF) 13F-HR Quarterly holdings report by institutional manager

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL

OMB Number:		3235-0006
Expires:	Oct 31, 2018
Estimated average burden
hours per response:		23.8

COLUMN 1	COLUMN 2	COLUMN 3	COLUMN 4	COLUMN 5			COLUMN 6	COLUMN 7	COLUMN 8
			VALUE	SHRS OR	SH/	PUT/	INVESTMENT	OTHER	VOTING AUTHORITY
NAME OF ISSUER	TITLE OF CLASS	CUSIP	(x$1000)	PRN AMT	PRN	CALL	DISCRETION	MANAGER	SOLE	SHARED	NONE
1LIFE HEALTHCARE INC	COM	68269G107	27,829	637,553	SH		DFND	2	637,553	0	0
10X GENOMICS INC	CL A COM	88025U109	23,381	165,123	SH		DFND	2	165,123	0	0
ABBOTT LABS	COM	002824100	152,944	1,396,873	SH		DFND	2	1,396,873	0	0
ABBVIE INC	COM	00287Y109	40,235	375,500	SH		DFND	2	375,500	0	0
ABIOMED INC	COM	003654100	34,870	107,557	SH		DFND	2	107,557	0	0
ACADIA PHARMACEUTICALS INC	COM	004225108	2,400	44,900	SH		DFND	2	44,900	0	0
ACCOLADE INC	COM	00437E102	16,761	385,308	SH		DFND	2	385,308	0	0
AGILENT TECHNOLOGIES INC	COM	00846U101	2,773	23,400	SH		DFND	2	23,400	0	0
AGIOS PHARMACEUTICALS INC	COM	00847X104	1,824	42,100	SH		DFND	2	42,100	0	0
AGIOS PHARMACEUTICALS INC	COM	00847X104	180,205	4,158,902	SH		DFND	1,2	4,158,902	0	0
ALEXION PHARMACEUTICALS INC	COM	015351109	15,405	98,600	SH		DFND	2	98,600	0	0
ALEXION PHARMACEUTICALS INC	COM	015351109	202,241	1,294,428	SH		DFND	1,2	1,294,428	0	0
ALIGN TECHNOLOGY INC	COM	016255101	60,261	112,768	SH		DFND	2	112,768	0	0
ALLAKOS INC	COM	01671P100	2,590	18,500	SH		DFND	2	18,500	0	0
ALNYLAM PHARMACEUTICALS INC	COM	02043Q107	8,188	63,000	SH		DFND	2	63,000	0	0
ALNYLAM PHARMACEUTICALS INC	COM	02043Q107	150,115	1,155,000	SH		DFND	1,2	1,155,000	0	0
ALNYLAM PHARMACEUTICALS INC	COM	02043Q107	50,103	385,500	SH		DFND	3	385,500	0	0
AMEDISYS INC	COM	023436108	20,882	71,190	SH		DFND	2	71,190	0	0
AMERICAN EXPRESS CO	COM	025816109	435	3,600	SH		DFND	2	3,600	0	0
AMERICAN WELL CORP	CL A	03044L105	23,865	942,154	SH		DFND	2	942,154	0	0
AMGEN INC	COM	031162100	11,232	48,850	SH		DFND	2	48,850	0	0
AMGEN INC	COM	031162100	38,889	169,140	SH		DFND	3	169,140	0	0
ANALOG DEVICES INC	COM	032654105	606	4,100	SH		DFND	2	4,100	0	0
ANSYS INC	COM	03662Q105	451	1,240	SH		DFND	2	1,240	0	0
ANTHEM INC	COM	036752103	45,716	142,378	SH		DFND	2	142,378	0	0
ANTHEM INC	COM	036752103	62,104	193,415	SH		DFND	3	193,415	0	0
APELLIS PHARMACEUTICALS INC	COM	03753U106	2,746	48,000	SH		DFND	2	48,000	0	0
ARCUS BIOSCIENCES INC	COM	03969F109	1,324	51,000	SH		DFND	2	51,000	0	0
ARGENX SE	SPONSORED ADR	04016X101	7,063	24,016	SH		DFND	2	24,016	0	0
ARGENX SE	SPONSORED ADR	04016X101	270,955	921,332	SH		DFND	1,2	921,332	0	0
ARVINAS INC	COM	04335A105	1,240	14,600	SH		DFND	2	14,600	0	0
ARVINAS INC	COM	04335A105	184,884	2,176,903	SH		DFND	1,2	2,176,903	0	0
ASCENDIS PHARMA A S	SPONSORED ADR	04351P101	2,585	15,500	SH		DFND	2	15,500	0	0
ASPEN TECHNOLOGY INC	COM	045327103	391	3,000	SH		DFND	2	3,000	0	0
ATRICURE INC	COM	04963C209	30,973	556,374	SH		DFND	3	556,374	0	0
AUTOLIV INC	COM	052800109	626	6,800	SH		DFND	2	6,800	0	0
AVANTOR INC	COM	05352A100	14,419	512,216	SH		DFND	2	512,216	0	0
AVIENT CORPORATION	COM	05368V106	548	13,600	SH		DFND	2	13,600	0	0
AXONICS MODULATION TECHNOLOG	COM	05465P101	35,261	706,357	SH		DFND	2	706,357	0	0
AXONICS MODULATION TECHNOLOG	COM	05465P101	23,094	462,621	SH		DFND	3	462,621	0	0
BAXTER INTL INC	COM	071813109	38,084	474,623	SH		DFND	2	474,623	0	0
BEAM THERAPEUTICS INC	COM	07373V105	32,396	396,821	SH		DFND	1,2	396,821	0	0
BECTON DICKINSON & CO	COM	075887109	82,011	327,756	SH		DFND	2	327,756	0	0
BEIGENE LTD	SPONSORED ADR	07725L102	27,674	107,100	SH		DFND	2	107,100	0	0
BERKELEY LTS INC	COM	084310101	14,351	160,505	SH		DFND	2	160,505	0	0
BIOGEN INC	COM	09062X103	6,611	27,000	SH		DFND	2	27,000	0	0
BIOGEN INC	COM	09062X103	131,490	537,000	SH		DFND	1,2	537,000	0	0
BIOHAVEN PHARMACTL HLDG CO L	COM	G11196105	1,071	12,500	SH		DFND	2	12,500	0	0
BIONTECH SE	SPONSORED ADS	09075V102	1,467	18,000	SH		DFND	2	18,000	0	0
BIO RAD LABS INC	CL A	090572207	37,544	64,405	SH		DFND	3	64,405	0	0
BLACKBAUD INC	COM	09227Q100	236	4,107	SH		DFND	2	4,107	0	0
BLACK DIAMOND THERAPEUTICS I	COM	09203E105	417	13,000	SH		DFND	2	13,000	0	0
BLACK DIAMOND THERAPEUTICS I	COM	09203E105	44,550	1,390,000	SH		DFND	1,2	1,390,000	0	0
BOOKING HOLDINGS INC	COM	09857L108	445	200	SH		DFND	2	200	0	0
BOSTON SCIENTIFIC CORP	COM	101137107	79,444	2,209,859	SH		DFND	2	2,209,859	0	0
BRISTOL-MYERS SQUIBB CO	COM	110122108	36,163	583,000	SH		DFND	2	583,000	0	0
BRISTOL-MYERS SQUIBB CO	COM	110122108	75,768	1,221,472	SH		DFND	3	1,221,472	0	0
BRISTOL-MYERS SQUIBB CO	RIGHT 99/99/9999	110122157	552	800,000	SH		DFND	1,2	800,000	0	0
BRISTOL-MYERS SQUIBB CO	RIGHT 99/99/9999	110122157	1,944	2,817,446	SH		DFND	3	2,817,446	0	0
BROADRIDGE FINL SOLUTIONS IN	COM	11133T103	521	3,400	SH		DFND	2	3,400	0	0
BROWN FORMAN CORP	CL B	115637209	445	5,600	SH		DFND	2	5,600	0	0
BURNING ROCK BIOTECH LTD	SPONSORED ADR	12233L107	4,280	185,286	SH		DFND	2	185,286	0	0
CAREDX INC	COM	14167L103	24,922	343,983	SH		DFND	3	343,983	0	0
CATALENT INC	COM	148806102	489	4,700	SH		DFND	2	4,700	0	0
CELLECTIS S A	SPON ADS	15117K103	2,260	83,500	SH		DFND	2	83,500	0	0
CENTENE CORP DEL	COM	15135B101	71,138	1,185,047	SH		DFND	2	1,185,047	0	0
CHANGE HEALTHCARE INC	COM	15912K100	33,308	1,785,974	SH		DFND	2	1,785,974	0	0
CHARLES RIV LABS INTL INC	COM	159864107	35,734	143,018	SH		DFND	3	143,018	0	0
CIDARA THERAPEUTICS INC	COM	171757107	5,645	2,822,495	SH		DFND	1,2	2,822,495	0	0
CIGNA CORP NEW	COM	125523100	86,022	413,208	SH		DFND	2	413,208	0	0
CLOROX CO DEL	COM	189054109	404	2,000	SH		DFND	2	2,000	0	0
COHERUS BIOSCIENCES INC	COM	19249H103	2,590	149,000	SH		DFND	2	149,000	0	0
CONSTELLATION BRANDS INC	CL A	21036P108	451	2,059	SH		DFND	2	2,059	0	0
COOPER COS INC	COM NEW	216648402	15,808	43,510	SH		DFND	2	43,510	0	0
COSTAR GROUP INC	COM	22160N109	462	500	SH		DFND	2	500	0	0
COVETRUS INC	COM	22304C100	44	1,520	SH		DFND	2	1,520	0	0
CRISPR THERAPEUTICS AG	NAMEN AKT	H17182108	1,347	8,800	SH		DFND	2	8,800	0	0
CRISPR THERAPEUTICS AG	NAMEN AKT	H17182108	137,934	900,884	SH		DFND	1,2	900,884	0	0
CUREVAC NV	COM	N2451R105	1,378	17,000	SH		DFND	2	17,000	0	0
CVS HEALTH CORP	COM	126650100	8,237	120,595	SH		DFND	2	120,595	0	0
CYBERARK SOFTWARE LTD	SHS	M2682V108	695	4,300	SH		DFND	2	4,300	0	0
DANAHER CORPORATION	COM	235851102	118,577	533,794	SH		DFND	2	533,794	0	0
DAVITA INC	COM	23918K108	41,466	353,200	SH		DFND	2	353,200	0	0
DENTSPLY SIRONA INC	COM	24906P109	8,332	159,129	SH		DFND	2	159,129	0	0
DEXCOM INC	COM	252131107	78,864	213,307	SH		DFND	2	213,307	0	0
DICERNA PHARMACEUTICALS INC	COM	253031108	1,498	68,000	SH		DFND	2	68,000	0	0
DOMINOS PIZZA INC	COM	25754A201	383	1,000	SH		DFND	2	1,000	0	0
DR REDDYS LABS LTD	ADR	256135203	606	8,500	SH		DFND	2	8,500	0	0
EARGO INC	COM	270087109	8,808	196,522	SH		DFND	2	196,522	0	0
EDWARDS LIFESCIENCES CORP	COM	28176E108	75,440	826,918	SH		DFND	2	826,918	0	0
ELECTRONIC ARTS INC	COM	285512109	470	3,270	SH		DFND	2	3,270	0	0
ENTEGRIS INC	COM	29362U104	509	5,300	SH		DFND	2	5,300	0	0
ESPERION THERAPEUTICS INC NE	COM	29664W105	1,071	41,200	SH		DFND	2	41,200	0	0
ESPERION THERAPEUTICS INC NE	COM	29664W105	102,647	3,947,964	SH		DFND	1,2	3,947,964	0	0
ESPERION THERAPEUTICS INC NE	COM	29664W105	29,881	1,149,287	SH		DFND	3	1,149,287	0	0
EVOLENT HEALTH INC	CL A	30050B101	25,304	1,578,529	SH		DFND	2	1,578,529	0	0
EVOLENT HEALTH INC	CL A	30050B101	25,176	1,570,582	SH		DFND	3	1,570,582	0	0
EXACT SCIENCES CORP	COM	30063P105	25,836	195,000	SH		DFND	3	195,000	0	0
EXELIXIS INC	COM	30161Q104	2,198	109,500	SH		DFND	2	109,500	0	0
EXELIXIS INC	COM	30161Q104	56,898	2,835,000	SH		DFND	1,2	2,835,000	0	0
FACTSET RESH SYS INC	COM	303075105	432	1,300	SH		DFND	2	1,300	0	0
FASTENAL CO	COM	311900104	488	10,000	SH		DFND	2	10,000	0	0
FATE THERAPEUTICS INC	COM	31189P102	7,047	77,500	SH		DFND	2	77,500	0	0
FATE THERAPEUTICS INC	COM	31189P102	184,588	2,030,000	SH		DFND	1,2	2,030,000	0	0
FIBROGEN INC	COM	31572Q808	1,966	53,000	SH		DFND	2	53,000	0	0
FORTINET INC	COM	34959E109	431	2,900	SH		DFND	2	2,900	0	0
GALAPAGOS NV	SPON ADR	36315X101	940	9,500	SH		DFND	2	9,500	0	0
GARTNER INC	COM	366651107	545	3,400	SH		DFND	2	3,400	0	0
GENERATION BIO CO	COM	37148K100	66,146	2,333,180	SH		DFND	1,2	2,333,180	0	0
GENETRON HLDGS LTD	ADS	37186H100	2,448	174,849	SH		DFND	2	174,849	0	0
GENMARK DIAGNOSTICS INC	COM	372309104	38,057	2,606,636	SH		DFND	3	2,606,636	0	0
GILEAD SCIENCES INC	COM	375558103	4,929	84,600	SH		DFND	2	84,600	0	0
GLAUKOS CORP	COM	377322102	33,817	449,332	SH		DFND	2	449,332	0	0
GLOBUS MED INC	CL A	379577208	38,128	584,612	SH		DFND	2	584,612	0	0
GOHEALTH INC	COM CL A	38046W105	4,609	337,423	SH		DFND	2	337,423	0	0
GRACO INC	COM	384109104	478	6,600	SH		DFND	2	6,600	0	0
GUARDANT HEALTH INC	COM	40131M109	23,101	179,241	SH		DFND	2	179,241	0	0
GW PHARMACEUTICALS PLC	ADS	36197T103	1,154	10,000	SH		DFND	2	10,000	0	0
GW PHARMACEUTICALS PLC	ADS	36197T103	53,364	462,389	SH		DFND	3	462,389	0	0
HALOZYME THERAPEUTICS INC	COM	40637H109	3,203	75,000	SH		DFND	2	75,000	0	0
HALOZYME THERAPEUTICS INC	COM	40637H109	169,559	3,970,000	SH		DFND	1,2	3,970,000	0	0
HCA HEALTHCARE INC	COM	40412C101	60,364	367,044	SH		DFND	2	367,044	0	0
HEALTH CATALYST INC	COM	42225T107	26,998	620,210	SH		DFND	2	620,210	0	0
HILL ROM HLDGS INC	COM	431475102	63,928	652,525	SH		DFND	3	652,525	0	0
HOLOGIC INC	COM	436440101	37,686	517,448	SH		DFND	2	517,448	0	0
HOLOGIC INC	COM	436440101	28,487	391,140	SH		DFND	3	391,140	0	0
HOMOLOGY MEDICINES INC	COM	438083107	19,612	1,737,122	SH		DFND	1,2	1,737,122	0	0
HORIZON THERAPEUTICS PUB L	SHS	G46188101	27,812	380,200	SH		DFND	2	380,200	0	0
HUMANA INC	COM	444859102	54,131	131,941	SH		DFND	2	131,941	0	0
HUMANA INC	COM	444859102	43,130	105,126	SH		DFND	3	105,126	0	0
HUTCHISON CHINA MEDITECH LTD	SPONSORED ADR	44842L103	30,345	947,674	SH		DFND	3	947,674	0	0
IDEXX LABS INC	COM	45168D104	39,032	78,085	SH		DFND	2	78,085	0	0
ILLUMINA INC	COM	452327109	19,375	52,366	SH		DFND	2	52,366	0	0
I MAB	SPONSORED ADS	44975P103	9,581	203,212	SH		DFND	2	203,212	0	0
INCYTE CORP	COM	45337C102	9,455	108,700	SH		DFND	2	108,700	0	0
INCYTE CORP	COM	45337C102	252,242	2,900,000	SH		DFND	1,2	2,900,000	0	0
INOGEN INC	COM	45780L104	8,004	179,143	SH		DFND	2	179,143	0	0
INSMED INC	COM PAR $.01	457669307	53,830	1,617,000	SH		DFND	3	1,617,000	0	0
INSPIRE MED SYS INC	COM	457730109	56,280	299,217	SH		DFND	2	299,217	0	0
INSULET CORP	COM	45784P101	86,267	337,468	SH		DFND	2	337,468	0	0
INTERACTIVE BROKERS GROUP IN	COM CL A	45841N107	573	9,400	SH		DFND	2	9,400	0	0
INTERCEPT PHARMACEUTICALS IN	COM	45845P108	198	8,000	SH		DFND	2	8,000	0	0
INTERCONTINENTAL EXCHANGE IN	COM	45866F104	553	4,800	SH		DFND	2	4,800	0	0
INTERSECT ENT INC	COM	46071F103	14,186	619,481	SH		DFND	2	619,481	0	0
INTRA CELLULAR THERAPIES INC	COM	46116X101	3,864	121,500	SH		DFND	2	121,500	0	0
INTRA CELLULAR THERAPIES INC	COM	46116X101	112,522	3,538,419	SH		DFND	1,2	3,538,419	0	0
INTUITIVE SURGICAL INC	COM NEW	46120E602	160,364	196,020	SH		DFND	2	196,020	0	0
IONIS PHARMACEUTICALS INC	COM	462222100	10,576	187,050	SH		DFND	2	187,050	0	0
IONIS PHARMACEUTICALS INC	COM	462222100	464,759	8,220,000	SH		DFND	1,2	8,220,000	0	0
IONIS PHARMACEUTICALS INC	COM	462222100	36,358	643,042	SH		DFND	3	643,042	0	0
IPG PHOTONICS CORP	COM	44980X109	526	2,350	SH		DFND	2	2,350	0	0
IQVIA HLDGS INC	COM	46266C105	520	2,900	SH		DFND	2	2,900	0	0
IRHYTHM TECHNOLOGIES INC	COM	450056106	23,389	98,602	SH		DFND	2	98,602	0	0
JAZZ PHARMACEUTICALS PLC	SHS USD	G50871105	6,569	39,800	SH		DFND	2	39,800	0	0
JAZZ PHARMACEUTICALS PLC	SHS USD	G50871105	57,613	349,065	SH		DFND	3	349,065	0	0
JD.COM INC	SPON ADR CL A	47215P106	466	5,300	SH		DFND	2	5,300	0	0
JOHNSON & JOHNSON	COM	478160104	4,407	28,000	SH		DFND	2	28,000	0	0
KEZAR LIFE SCIENCES INC	COM	49372L100	23,663	4,533,148	SH		DFND	1,2	4,533,148	0	0
KOSMOS ENERGY LTD	COM	500688106	999	425,000	SH		DFND	2	425,000	0	0
KURA ONCOLOGY INC	COM	50127T109	1,894	58,000	SH		DFND	2	58,000	0	0
LABORATORY CORP AMER HLDGS	COM NEW	50540R409	3,874	19,033	SH		DFND	2	19,033	0	0
LAUDER ESTEE COS INC	CL A	518439104	598	2,248	SH		DFND	2	2,248	0	0
LEGEND BIOTECH CORP	SPONSORED ADS	52490G102	11,724	416,341	SH		DFND	2	416,341	0	0
LIVE NATION ENTERTAINMENT IN	COM	538034109	456	6,200	SH		DFND	2	6,200	0	0
MACROGENICS INC	COM	556099109	1,142	49,950	SH		DFND	2	49,950	0	0
MACROGENICS INC	COM	556099109	110,084	4,815,564	SH		DFND	1,2	4,815,564	0	0
MACROGENICS INC	COM	556099109	23,752	1,039,003	SH		DFND	3	1,039,003	0	0
MARKEL CORP	COM	570535104	413	400	SH		DFND	2	400	0	0
MARKETAXESS HLDGS INC	COM	57060D108	469	822	SH		DFND	2	822	0	0
MASIMO CORP	COM	574795100	28,938	107,824	SH		DFND	2	107,824	0	0
MATCH GROUP INC NEW	COM	57667L107	586	3,878	SH		DFND	2	3,878	0	0
MCCORMICK & CO INC	COM NON VTG	579780206	421	4,400	SH		DFND	2	4,400	0	0
MCKESSON CORP	COM	58155Q103	423	2,430	SH		DFND	2	2,430	0	0
MEDTRONIC PLC	SHS	G5960L103	54,032	461,258	SH		DFND	2	461,258	0	0
MERCADOLIBRE INC	COM	58733R102	570	340	SH		DFND	2	340	0	0
MERSANA THERAPEUTICS INC	COM	59045L106	1,091	41,010	SH		DFND	2	41,010	0	0
MERSANA THERAPEUTICS INC	COM	59045L106	50,160	1,885,000	SH		DFND	1,2	1,885,000	0	0
METTLER TOLEDO INTERNATIONAL	COM	592688105	479	420	SH		DFND	2	420	0	0
MIRATI THERAPEUTICS INC	COM	60468T105	2,702	12,300	SH		DFND	2	12,300	0	0
MODERNA INC	COM	60770K107	9,606	91,950	SH		DFND	2	91,950	0	0
MODERNA INC	COM	60770K107	298,258	2,854,963	SH		DFND	1,2	2,854,963	0	0
MOLECULAR TEMPLATES INC	COM	608550109	300	32,000	SH		DFND	2	32,000	0	0
MOLECULAR TEMPLATES INC	COM	608550109	59,911	6,380,331	SH		DFND	1,2	6,380,331	0	0
MOLINA HEALTHCARE INC	COM	60855R100	42,470	199,688	SH		DFND	2	199,688	0	0
MOODYS CORP	COM	615369105	435	1,500	SH		DFND	2	1,500	0	0
MSCI INC	COM	55354G100	530	1,186	SH		DFND	2	1,186	0	0
MYOVANT SCIENCES LTD	COM	G637AM102	1,298	47,000	SH		DFND	2	47,000	0	0
MYOVANT SCIENCES LTD	COM	G637AM102	131,389	4,757,039	SH		DFND	1,2	4,757,039	0	0
NEKTAR THERAPEUTICS	COM	640268108	490	28,800	SH		DFND	2	28,800	0	0
NEKTAR THERAPEUTICS	COM	640268108	44,551	2,620,676	SH		DFND	1,2	2,620,676	0	0
NEKTAR THERAPEUTICS	COM	640268108	20,685	1,216,782	SH		DFND	3	1,216,782	0	0
NEOGENOMICS INC	COM NEW	64049M209	29,528	548,446	SH		DFND	3	548,446	0	0
NEUROCRINE BIOSCIENCES INC	COM	64125C109	34,664	361,651	SH		DFND	2	361,651	0	0
NEUROCRINE BIOSCIENCES INC	COM	64125C109	290,905	3,035,000	SH		DFND	1,2	3,035,000	0	0
NEVRO CORP	COM	64157F103	22,573	130,402	SH		DFND	2	130,402	0	0
OMNICELL INC	COM	68213N109	35,562	296,303	SH		DFND	2	296,303	0	0
OPTHEA LTD	SPONSORED ADS	68386J208	568	50,000	SH		DFND	2	50,000	0	0
OUTSET MED INC	COM	690145107	10,783	189,711	SH		DFND	2	189,711	0	0
OXFORD IMMUNOTEC GLOBAL PLC	ORD SHS	G6855A103	13,975	800,157	SH		DFND	2	800,157	0	0
PACIFIC BIOSIENCES CALIF IN	COM	69404D108	44,051	1,698,179	SH		DFND	2	1,698,179	0	0
PAYCHEX INC	COM	704326107	503	5,400	SH		DFND	2	5,400	0	0
PENUMBRA INC	COM	70975L107	25,812	147,495	SH		DFND	2	147,495	0	0
PERKINELMER INC	COM	714046109	502	3,500	SH		DFND	2	3,500	0	0
PFIZER INC	COM	717081103	2,720	73,900	SH		DFND	2	73,900	0	0
PHREESIA INC	COM	71944F106	25,650	472,720	SH		DFND	2	472,720	0	0
POOL CORP	COM	73278L105	447	1,200	SH		DFND	2	1,200	0	0
PULMONX CORP	COM	745848101	12,183	176,510	SH		DFND	2	176,510	0	0
QUANTERIX CORP	COM	74766Q101	33,154	712,999	SH		DFND	2	712,999	0	0
QUEST DIAGNOSTICS INC	COM	74834L100	804	6,749	SH		DFND	2	6,749	0	0
QUOTIENT LTD	SHS	G73268107	3,425	657,354	SH		DFND	2	657,354	0	0
RADIUS HEALTH INC	COM NEW	750469207	1,352	75,700	SH		DFND	2	75,700	0	0
RADIUS HEALTH INC	COM NEW	750469207	133,159	7,455,714	SH		DFND	1,2	7,455,714	0	0
REGENERON PHARMACEUTICALS	COM	75886F107	13,382	27,700	SH		DFND	2	27,700	0	0
RELAY THERAPEUTICS INC	COM	75943R102	58,573	1,409,357	SH		DFND	1,2	1,409,357	0	0
RESMED INC	COM	761152107	21,038	98,975	SH		DFND	2	98,975	0	0
REVOLUTION MEDICINES INC	COM	76155X100	1,584	40,000	SH		DFND	2	40,000	0	0
S&P GLOBAL INC	COM	78409V104	394	1,200	SH		DFND	2	1,200	0	0
SAGE THERAPEUTICS INC	COM	78667J108	2,370	27,400	SH		DFND	2	27,400	0	0
SAGE THERAPEUTICS INC	COM	78667J108	133,234	1,540,104	SH		DFND	1,2	1,540,104	0	0
SAREPTA THERAPEUTICS INC	COM	803607100	3,461	20,300	SH		DFND	2	20,300	0	0
SCHOLAR ROCK HLDG CORP	COM	80706P103	1,504	31,000	SH		DFND	2	31,000	0	0
SCHOLAR ROCK HLDG CORP	COM	80706P103	109,467	2,255,651	SH		DFND	1,2	2,255,651	0	0
SEAGEN INC	COM	81181C104	8,162	46,600	SH		DFND	2	46,600	0	0
SEER INC	COM CL A	81578P106	4,229	75,336	SH		DFND	2	75,336	0	0
SENSATA TECHNOLOGIES HLDNG PL	SHS	G8060N102	522	9,900	SH		DFND	2	9,900	0	0
SERVICE CORP INTL	COM	817565104	417	8,500	SH		DFND	2	8,500	0	0
SHOCKWAVE MED INC	COM	82489T104	44,116	425,335	SH		DFND	2	425,335	0	0
SILK RD MED INC	COM	82710M100	23,485	372,890	SH		DFND	2	372,890	0	0
SKYWORKS SOLUTIONS INC	COM	83088M102	428	2,800	SH		DFND	2	2,800	0	0
SOCIEDAD QUIMICA Y MINERA DE	SPON ADR SER B	833635105	893	18,200	SH		DFND	2	18,200	0	0
STARBUCKS CORP	COM	855244109	464	4,334	SH		DFND	2	4,334	0	0
STONECO LTD	COM CL A	G85158106	629	7,500	SH		DFND	2	7,500	0	0
STRYKER CORPORATION	COM	863667101	82,827	338,015	SH		DFND	2	338,015	0	0
TABULA RASA HEALTHCARE INC	COM	873379101	9,338	217,975	SH		DFND	2	217,975	0	0
TANDEM DIABETES CARE INC	COM NEW	875372203	36,854	385,184	SH		DFND	2	385,184	0	0
TELADOC HEALTH INC	COM	87918A105	42,062	210,352	SH		DFND	2	210,352	0	0
TELEFLEX INCORPORATED	COM	879369106	48,474	117,778	SH		DFND	2	117,778	0	0
THERMO FISHER SCIENTIFIC INC	COM	883556102	20,706	44,455	SH		DFND	2	44,455	0	0
TRADEWEB MKTS INC	CL A	892672106	425	6,800	SH		DFND	2	6,800	0	0
TRANSMEDICS GROUP INC	COM	89377M109	12,768	641,612	SH		DFND	2	641,612	0	0
TRANSUNION	COM	89400J107	506	5,096	SH		DFND	2	5,096	0	0
TRIMBLE INC	COM	896239100	554	8,300	SH		DFND	2	8,300	0	0
TRIP COM GROUP LTD	ADS	89677Q107	442	13,100	SH		DFND	2	13,100	0	0
TYLER TECHNOLOGIES INC	COM	902252105	480	1,100	SH		DFND	2	1,100	0	0
ULTA BEAUTY INC	COM	90384S303	574	2,000	SH		DFND	2	2,000	0	0
ULTRAGENYX PHARMACEUTICAL IN	COM	90400D108	5,676	41,000	SH		DFND	2	41,000	0	0
UNIQURE NV	SHS	N90064101	1,246	34,500	SH		DFND	2	34,500	0	0
UNITEDHEALTH GROUP INC	COM	91324P102	75,122	214,218	SH		DFND	2	214,218	0	0
UNITEDHEALTH GROUP INC	COM	91324P102	32,202	91,827	SH		DFND	3	91,827	0	0
VEEVA SYS INC	CL A COM	922475108	30,476	111,941	SH		DFND	2	111,941	0	0
VERISIGN INC	COM	92343E102	454	2,100	SH		DFND	2	2,100	0	0
VERISK ANALYTICS INC	COM	92345Y106	517	2,489	SH		DFND	2	2,489	0	0
VERTEX PHARMACEUTICALS INC	COM	92532F100	16,213	68,600	SH		DFND	2	68,600	0	0
VERTEX PHARMACEUTICALS INC	COM	92532F100	63,903	270,385	SH		DFND	3	270,385	0	0
VERTEX PHARMACEUTICALS INC	COM	92532F100	212,706	900,000	SH		DFND	1,2	900,000	0	0
VIATRIS INC	COM	92556V106	172	9,169	SH		DFND	2	9,169	0	0
VOCERA COMMUNICATONS INC	COM	92857F107	11,137	268,171	SH		DFND	2	268,171	0	0
VOYAGER THERAPEUTICS INC	COM	92915B106	227	31,800	SH		DFND	2	31,800	0	0
VOYAGER THERAPEUTICS INC	COM	92915B106	19,164	2,680,283	SH		DFND	1,2	2,680,283	0	0
WABTEC	COM	929740108	468	6,400	SH		DFND	2	6,400	0	0
WATSCO INC	COM	942622200	408	1,800	SH		DFND	2	1,800	0	0
WAVE LIFE SCIENCES LTD	SHS	Y95308105	20,484	2,602,858	SH		DFND	1,2	2,602,858	0	0
XENCOR INC	COM	98401F105	1,531	35,100	SH		DFND	2	35,100	0	0
XILINX INC	COM	983919101	595	4,200	SH		DFND	2	4,200	0	0
ZAI LAB LTD	ADR	98887Q104	4,426	32,700	SH		DFND	2	32,700	0	0
ZIMMER BIOMET HOLDINGS INC	COM	98956P102	37,715	244,761	SH		DFND	2	244,761	0	0