Bellevue (BLVGF) 13F-HR Quarterly holdings report by institutional manager

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL

OMB Number:		3235-0006
Expires:	Oct 31, 2018
Estimated average burden
hours per response:		23.8

COLUMN 1	COLUMN 2	COLUMN 3	COLUMN 4	COLUMN 5			COLUMN 6	COLUMN 7	COLUMN 8
			VALUE	SHRS OR	SH/	PUT/	INVESTMENT	OTHER	VOTING AUTHORITY
NAME OF ISSUER	TITLE OF CLASS	CUSIP	(x$1000)	PRN AMT	PRN	CALL	DISCRETION	MANAGER	SOLE	SHARED	NONE
1LIFE HEALTHCARE INC	COM	68269G107	27,644	836,190	SH		DFND	2	836,190	0	0
10X GENOMICS INC	CL A COM	88025U109	45,562	232,672	SH		DFND	2	232,672	0	0
ABBOTT LABS	COM	002824100	159,693	1,377,499	SH		DFND	2	1,377,499	0	0
ABBVIE INC	COM	00287Y109	36,518	324,200	SH		DFND	2	324,200	0	0
ABIOMED INC	COM	003654100	47,184	151,178	SH		DFND	2	151,178	0	0
ACADIA PHARMACEUTICALS INC	COM	004225108	1,607	65,900	SH		DFND	2	65,900	0	0
ACCOLADE INC	COM	00437E102	37,391	688,479	SH		DFND	2	688,479	0	0
ACCOLADE INC	COM	00437E102	56,277	1,036,220	SH		DFND	3	1,036,220	0	0
ADAPTIVE BIOTECHNOLOGIES COR	COM	00650F109	39,322	962,352	SH		DFND	3	962,352	0	0
AGILENT TECHNOLOGIES INC	COM	00846U101	399	2,700	SH		DFND	2	2,700	0	0
AGIOS PHARMACEUTICALS INC	COM	00847X104	2,645	48,000	SH		DFND	2	48,000	0	0
AGIOS PHARMACEUTICALS INC	COM	00847X104	237,248	4,304,992	SH		DFND	1,2	4,304,992	0	0
ALEXION PHARMACEUTICALS INC	COM	015351109	2,627	14,300	SH		DFND	2	14,300	0	0
ALIGN TECHNOLOGY INC	COM	016255101	95,786	156,770	SH		DFND	2	156,770	0	0
ALLAKOS INC	COM	01671P100	1,579	18,500	SH		DFND	2	18,500	0	0
ALNYLAM PHARMACEUTICALS INC	COM	02043Q107	8,985	53,000	SH		DFND	2	53,000	0	0
ALNYLAM PHARMACEUTICALS INC	COM	02043Q107	188,167	1,110,000	SH		DFND	1,2	1,110,000	0	0
ALNYLAM PHARMACEUTICALS INC	COM	02043Q107	65,450	386,092	SH		DFND	3	386,092	0	0
AMEDISYS INC	COM	023436108	14,815	60,487	SH		DFND	2	60,487	0	0
AMERICAN EXPRESS CO	COM	025816109	430	2,600	SH		DFND	2	2,600	0	0
AMERICAN WELL CORP	CL A	03044L105	26,943	2,141,758	SH		DFND	2	2,141,758	0	0
AMGEN INC	COM	031162100	10,201	41,850	SH		DFND	2	41,850	0	0
AMGEN INC	COM	031162100	21,384	87,730	SH		DFND	3	87,730	0	0
ANSYS INC	COM	03662Q105	312	900	SH		DFND	2	900	0	0
ANTHEM INC	COM	036752103	105,063	275,179	SH		DFND	2	275,179	0	0
ANTHEM INC	COM	036752103	72,846	190,797	SH		DFND	3	190,797	0	0
APELLIS PHARMACEUTICALS INC	COM	03753U106	3,034	48,000	SH		DFND	2	48,000	0	0
ARCUS BIOSCIENCES INC	COM	03969F109	2,060	75,000	SH		DFND	2	75,000	0	0
ARGENX SE	SPONSORED ADR	04016X101	5,570	18,500	SH		DFND	2	18,500	0	0
ARGENX SE	SPONSORED ADR	04016X101	287,684	955,538	SH		DFND	1,2	955,538	0	0
ARVINAS INC	COM	04335A105	4,659	60,500	SH		DFND	2	60,500	0	0
ARVINAS INC	COM	04335A105	167,622	2,176,903	SH		DFND	1,2	2,176,903	0	0
ASPEN TECHNOLOGY INC	COM	045327103	330	2,400	SH		DFND	2	2,400	0	0
ATRICURE INC	COM	04963C209	29,703	374,418	SH		DFND	3	374,418	0	0
AVALARA INC	COM	05338G106	372	2,300	SH		DFND	2	2,300	0	0
AVANTOR INC	COM	05352A100	18,189	512,216	SH		DFND	2	512,216	0	0
AXONICS INC	COM	05465P101	63,402	999,881	SH		DFND	2	999,881	0	0
AXONICS INC	COM	05465P101	46,327	730,590	SH		DFND	3	730,590	0	0
AXSOME THERAPEUTICS INC	COM	05464T104	23,747	352,021	SH		DFND	3	352,021	0	0
BAXTER INTL INC	COM	071813109	72,500	900,623	SH		DFND	2	900,623	0	0
BEAM THERAPEUTICS INC	COM	07373V105	772	6,000	SH		DFND	2	6,000	0	0
BEAM THERAPEUTICS INC	COM	07373V105	78,104	606,821	SH		DFND	1,2	606,821	0	0
BECTON DICKINSON & CO	COM	075887109	112,102	460,965	SH		DFND	2	460,965	0	0
BEIGENE LTD	SPONSORED ADR	07725L102	28,931	84,300	SH		DFND	2	84,300	0	0
BERKELEY LTS INC	COM	084310101	17,252	385,014	SH		DFND	2	385,014	0	0
BIOGEN INC	COM	09062X103	9,730	28,100	SH		DFND	2	28,100	0	0
BIOGEN INC	COM	09062X103	173,135	500,000	SH		DFND	1,2	500,000	0	0
BIOHAVEN PHARMACTL HLDG CO L	COM	G11196105	3,495	36,000	SH		DFND	2	36,000	0	0
BIONTECH SE	SPONSORED ADS	09075V102	5,060	22,600	SH		DFND	2	22,600	0	0
BIOMARIN PHARMACEUTICAL INC	COM	09061G101	3,379	40,500	SH		DFND	2	40,500	0	0
BIO RAD LABS INC	CL A	090572207	56,247	87,301	SH		DFND	3	87,301	0	0
BLACK DIAMOND THERAPEUTICS I	COM	09203E105	280	23,000	SH		DFND	2	23,000	0	0
BLACK DIAMOND THERAPEUTICS I	COM	09203E105	41,934	3,440,000	SH		DFND	1,2	3,440,000	0	0
BOOKING HOLDINGS INC	COM	09857L108	350	160	SH		DFND	2	160	0	0
BOSTON SCIENTIFIC CORP	COM	101137107	99,493	2,326,787	SH		DFND	2	2,326,787	0	0
BRIGHT HEALTH GROUP INC	COM	10920V107	25,740	1,500,000	SH		DFND	2	1,500,000	0	0
BRISTOL-MYERS SQUIBB CO	COM	110122108	4,510	67,500	SH		DFND	2	67,500	0	0
BRISTOL-MYERS SQUIBB CO	COM	110122108	93,276	1,395,932	SH		DFND	3	1,395,932	0	0
BROWN FORMAN CORP	CL B	115637209	345	4,600	SH		DFND	2	4,600	0	0
BURNING ROCK BIOTECH LTD	SPONSORED ADR	12233L107	14,432	489,890	SH		DFND	2	489,890	0	0
C4 THERAPEUTICS INC	COM STK	12529R107	1,173	31,000	SH		DFND	2	31,000	0	0
CAREDX INC	COM	14167L103	13,625	148,871	SH		DFND	3	148,871	0	0
CARMAX INC	COM	143130102	368	2,850	SH		DFND	2	2,850	0	0
CATALENT INC	COM	148806102	292	2,700	SH		DFND	2	2,700	0	0
CELLECTIS S A	SPON ADS	15117K103	1,292	83,500	SH		DFND	2	83,500	0	0
CENTENE CORP DEL	COM	15135B101	101,103	1,386,297	SH		DFND	2	1,386,297	0	0
CHARLES RIV LABS INTL INC	COM	159864107	65,946	178,270	SH		DFND	3	178,270	0	0
CIGNA CORP NEW	COM	125523100	60,866	256,742	SH		DFND	2	256,742	0	0
CLOROX CO DEL	COM	189054109	360	2,000	SH		DFND	2	2,000	0	0
CONSTELLATION BRANDS INC	CL A	21036P108	341	1,459	SH		DFND	2	1,459	0	0
COOPER COS INC	COM NEW	216648402	29,429	74,266	SH		DFND	2	74,266	0	0
COSTAR GROUP INC	COM	22160N109	290	3,500	SH		DFND	2	3,500	0	0
CRISPR THERAPEUTICS AG	NAMEN AKT	H17182108	2,801	17,300	SH		DFND	2	17,300	0	0
CRISPR THERAPEUTICS AG	NAMEN AKT	H17182108	153,728	949,584	SH		DFND	1,2	949,584	0	0
CUREVAC N V	COM	N2451R105	39	70	SH	Call	DFND	2	70	0	0
CVS HEALTH CORP	COM	126650100	13,363	160,148	SH		DFND	2	160,148	0	0
CYBERARK SOFTWARE LTD	SHS	M2682V108	274	2,100	SH		DFND	2	2,100	0	0
DANAHER CORPORATION	COM	235851102	129,602	482,940	SH		DFND	2	482,940	0	0
DENTSPLY SIRONA INC	COM	24906P109	10,067	159,129	SH		DFND	2	159,129	0	0
DEXCOM INC	COM	252131107	104,519	244,776	SH		DFND	2	244,776	0	0
DICERNA PHARMACEUTICALS INC	COM	253031108	2,277	61,000	SH		DFND	2	61,000	0	0
DOLBY LABORATORIES INC	COM CL A	25659T107	354	3,600	SH		DFND	2	3,600	0	0
DOMINOS PIZZA INC	COM	25754A201	466	1,000	SH		DFND	2	1,000	0	0
DR REDDYS LABS LTD	ADR	256135203	625	8,500	SH		DFND	2	8,500	0	0
EARGO INC	COM	270087109	17,323	434,054	SH		DFND	2	434,054	0	0
EDWARDS LIFESCIENCES CORP	COM	28176E108	92,204	890,256	SH		DFND	2	890,256	0	0
ELECTRONIC ARTS INC	COM	285512109	326	2,270	SH		DFND	2	2,270	0	0
ENTEGRIS INC	COM	29362U104	369	3,000	SH		DFND	2	3,000	0	0
ESPERION THERAPEUTICS INC NE	COM	29664W105	871	41,200	SH		DFND	2	41,200	0	0
ESPERION THERAPEUTICS INC NE	COM	29664W105	94,709	4,477,964	SH		DFND	1,2	4,477,964	0	0
ESSA PHARMA INC	COM NEW	29668H708	543	19,000	SH		DFND	2	19,000	0	0
ESSA PHARMA INC	COM NEW	29668H708	69,734	2,440,814	SH		DFND	1,2	2,440,814	0	0
EVOLENT HEALTH INC	CL A	30050B101	34,927	1,653,761	SH		DFND	2	1,653,761	0	0
EVOLENT HEALTH INC	CL A	30050B101	41,916	1,984,650	SH		DFND	3	1,984,650	0	0
EXACT SCIENCES CORP	COM	30063P105	34,269	275,673	SH		DFND	3	275,673	0	0
EXELIXIS INC	COM	30161Q104	1,767	97,000	SH		DFND	2	97,000	0	0
EXELIXIS INC	COM	30161Q104	51,654	2,835,000	SH		DFND	1,2	2,835,000	0	0
FACTSET RESH SYS INC	COM	303075105	352	1,050	SH		DFND	2	1,050	0	0
FASTENAL CO	COM	311900104	364	7,000	SH		DFND	2	7,000	0	0
FATE THERAPEUTICS INC	COM	31189P102	5,832	67,200	SH		DFND	2	67,200	0	0
FATE THERAPEUTICS INC	COM	31189P102	220,997	2,546,336	SH		DFND	1,2	2,546,336	0	0
FORTINET INC	COM	34959E109	524	2,200	SH		DFND	2	2,200	0	0
GARTNER INC	COM	366651107	509	2,100	SH		DFND	2	2,100	0	0
GENERATION BIO CO	COM	37148K100	673	25,000	SH		DFND	2	25,000	0	0
GENERATION BIO CO	COM	37148K100	65,991	2,453,180	SH		DFND	1,2	2,453,180	0	0
GENETRON HLDGS LTD	ADS	37186H100	14,564	723,137	SH		DFND	2	723,137	0	0
GILEAD SCIENCES INC	COM	375558103	7,643	111,000	SH		DFND	2	111,000	0	0
GLAUKOS CORP	COM	377322102	42,027	495,432	SH		DFND	2	495,432	0	0
GLOBUS MED INC	CL A	379577208	56,552	729,420	SH		DFND	2	729,420	0	0
GRACO INC	COM	384109104	341	4,500	SH		DFND	2	4,500	0	0
GUARDANT HEALTH INC	COM	40131M109	47,144	379,609	SH		DFND	2	379,609	0	0
HALOZYME THERAPEUTICS INC	COM	40637H109	40,528	892,500	SH		DFND	2	892,500	0	0
HALOZYME THERAPEUTICS INC	COM	40637H109	60,485	1,331,966	SH		DFND	1,2	1,331,966	0	0
HCA HEALTHCARE INC	COM	40412C101	69,108	334,273	SH		DFND	2	334,273	0	0
HEALTH CATALYST INC	COM	42225T107	41,834	753,621	SH		DFND	2	753,621	0	0
HILL-ROM HLDGS INC	COM	431475102	76,546	673,878	SH		DFND	3	673,878	0	0
HOLOGIC INC	COM	436440101	26,006	389,779	SH		DFND	2	389,779	0	0
HOLOGIC INC	COM	436440101	34,959	523,973	SH		DFND	3	523,973	0	0
HOMOLOGY MEDICINES INC	COM	438083107	12,629	1,737,122	SH		DFND	1,2	1,737,122	0	0
HORIZON THERAPEUTICS PUB L	SHS	G46188101	39,113	417,700	SH		DFND	2	417,700	0	0
HUMANA INC	COM	444859102	63,415	143,239	SH		DFND	2	143,239	0	0
HUMANA INC	COM	444859102	61,767	139,516	SH		DFND	3	139,516	0	0
HUTCHMED CHINA LTD	SPONSORED ADS	44842L103	33,959	864,760	SH		DFND	3	864,760	0	0
IDEXX LABS INC	COM	45168D104	74,599	118,120	SH		DFND	2	118,120	0	0
ILLUMINA INC	COM	452327109	35,647	75,330	SH		DFND	2	75,330	0	0
I MAB	SPONSORED ADS	44975P103	15,401	183,457	SH		DFND	2	183,457	0	0
INCYTE CORP	COM	45337C102	6,259	74,400	SH		DFND	2	74,400	0	0
INCYTE CORP	COM	45337C102	243,725	2,897,000	SH		DFND	1,2	2,897,000	0	0
INOGEN INC	COM	45780L104	18,304	280,863	SH		DFND	2	280,863	0	0
INSMED INC	COM PAR $.01	457669307	88,821	3,120,901	SH		DFND	3	3,120,901	0	0
INSPIRE MED SYS INC	COM	457730109	72,130	373,226	SH		DFND	2	373,226	0	0
INSULET CORP	COM	45784P101	88,425	322,119	SH		DFND	2	322,119	0	0
INTERCONTINENTAL EXCHANGE IN	COM	45866F104	356	3,000	SH		DFND	2	3,000	0	0
INTERSECT ENT INC	COM	46071F103	10,561	617,968	SH		DFND	2	617,968	0	0
INTRA-CELLULAR THERAPIES INC	COM	46116X101	4,960	121,500	SH		DFND	2	121,500	0	0
INTRA-CELLULAR THERAPIES INC	COM	46116X101	142,397	3,488,419	SH		DFND	1,2	3,488,419	0	0
INTUIT	COM	461202103	441	900	SH		DFND	2	900	0	0
INTUITIVE SURGICAL INC	COM NEW	46120E602	185,855	202,095	SH		DFND	2	202,095	0	0
IONIS PHARMACEUTICALS INC	COM	462222100	7,461	187,050	SH		DFND	2	187,050	0	0
IONIS PHARMACEUTICALS INC	COM	462222100	363,516	9,112,973	SH		DFND	1,2	9,112,973	0	0
IONIS PHARMACEUTICALS INC	COM	462222100	25,140	630,222	SH		DFND	3	630,222	0	0
IPG PHOTONICS CORP	COM	44980X109	285	1,350	SH		DFND	2	1,350	0	0
IQVIA HLDGS INC	COM	46266C105	42,988	177,400	SH		DFND	2	177,400	0	0
JAZZ PHARMACEUTICALS PLC	SHS USD	G50871105	7,354	41,400	SH		DFND	2	41,400	0	0
JAZZ PHARMACEUTICALS PLC	SHS USD	G50871105	89,415	503,350	SH		DFND	3	503,350	0	0
JD.COM INC	SPON ADR CL A	47215P106	287	3,600	SH		DFND	2	3,600	0	0
JOHNSON & JOHNSON	COM	478160104	5,107	31,000	SH		DFND	2	31,000	0	0
JUMIA TECHNOLOGIES AG	SPONSORED ADS	48138M105	546	18,000	SH		DFND	2	18,000	0	0
KEZAR LIFE SCIENCES INC	COM	49372L100	24,615	4,533,148	SH		DFND	1,2	4,533,148	0	0
KOSMOS ENERGY LTD	COM	500688106	1,010	292,000	SH		DFND	2	292,000	0	0
KURA ONCOLOGY INC	COM	50127T109	1,209	58,000	SH		DFND	2	58,000	0	0
LABORATORY CORP AMER HLDGS	COM NEW	50540R409	9,986	36,200	SH		DFND	2	36,200	0	0
LAUDER ESTEE COS INC	CL A	518439104	429	1,348	SH		DFND	2	1,348	0	0
LEGEND BIOTECH CORP	SPONSORED ADS	52490G102	16,016	390,163	SH		DFND	2	390,163	0	0
LIVE NATION ENTERTAINMENT IN	COM	538034109	412	4,700	SH		DFND	2	4,700	0	0
MACROGENICS INC	COM	556099109	1,342	49,950	SH		DFND	2	49,950	0	0
MACROGENICS INC	COM	556099109	168,562	6,275,564	SH		DFND	1,2	6,275,564	0	0
MACROGENICS INC	COM	556099109	28,217	1,050,512	SH		DFND	3	1,050,512	0	0
MARKEL CORP	COM	570535104	356	300	SH		DFND	2	300	0	0
MARKETAXESS HLDGS INC	COM	57060D108	307	662	SH		DFND	2	662	0	0
MASIMO CORP	COM	574795100	30,964	127,713	SH		DFND	2	127,713	0	0
MATCH GROUP INC NEW	COM	57667L107	383	2,378	SH		DFND	2	2,378	0	0
MCCORMICK & CO INC	COM NON VTG	579780206	353	4,000	SH		DFND	2	4,000	0	0
MCKESSON CORP	COM	58155Q103	465	2,430	SH		DFND	2	2,430	0	0
MEDTRONIC PLC	SHS	G5960L103	44,640	359,625	SH		DFND	2	359,625	0	0
MERCADOLIBRE INC	COM	58733R102	265	170	SH		DFND	2	170	0	0
MERSANA THERAPEUTICS INC	COM	59045L106	1,100	81,000	SH		DFND	2	81,000	0	0
MERSANA THERAPEUTICS INC	COM	59045L106	38,839	2,860,000	SH		DFND	1,2	2,860,000	0	0
METTLER TOLEDO INTERNATIONAL	COM	592688105	374	270	SH		DFND	2	270	0	0
MIRATI THERAPEUTICS INC	COM	60468T105	1,179	7,300	SH		DFND	2	7,300	0	0
MODERNA INC	COM	60770K107	21,689	92,300	SH		DFND	2	92,300	0	0
MODERNA INC	COM	60770K107	575,701	2,450,000	SH		DFND	1,2	2,450,000	0	0
MOLECULAR TEMPLATES INC	COM	608550109	673	86,000	SH		DFND	2	86,000	0	0
MOLECULAR TEMPLATES INC	COM	608550109	74,623	9,542,621	SH		DFND	1,2	9,542,621	0	0
MOLINA HEALTHCARE INC	COM	60855R100	50,292	198,734	SH		DFND	2	198,734	0	0
MOODYS CORP	COM	615369105	453	1,250	SH		DFND	2	1,250	0	0
MSCI INC	COM	55354G100	435	816	SH		DFND	2	816	0	0
MYOVANT SCIENCES LTD	COM	G637AM102	1,070	47,000	SH		DFND	2	47,000	0	0
MYOVANT SCIENCES LTD	COM	G637AM102	118,906	5,222,039	SH		DFND	1,2	5,222,039	0	0
NEKTAR THERAPEUTICS	COM	640268108	494	28,800	SH		DFND	2	28,800	0	0
NEKTAR THERAPEUTICS	COM	640268108	44,971	2,620,676	SH		DFND	1,2	2,620,676	0	0
NEKTAR THERAPEUTICS	COM	640268108	24,915	1,451,928	SH		DFND	3	1,451,928	0	0
NEOGENOMICS INC	COM NEW	64049M209	36,963	818,313	SH		DFND	3	818,313	0	0
NEUROCRINE BIOSCIENCES INC	COM	64125C109	9,961	102,351	SH		DFND	2	102,351	0	0
NEUROCRINE BIOSCIENCES INC	COM	64125C109	283,727	2,915,400	SH		DFND	1,2	2,915,400	0	0
NEUROPACE INC	COM	641288105	12,084	507,930	SH		DFND	2	507,930	0	0
NEVRO CORP	COM	64157F103	30,373	183,201	SH		DFND	2	183,201	0	0
NEW YORK TIMES CO	CL A	650111107	327	7,500	SH		DFND	2	7,500	0	0
OLINK HLDG AB	SPONSORED ADS	680710100	6,799	197,527	SH		DFND	2	197,527	0	0
OMNICELL INC	COM	68213N109	59,608	393,583	SH		DFND	2	393,583	0	0
OPTHEA LTD	SPONSORED ADS	68386J208	397	50,000	SH		DFND	2	50,000	0	0
OPTION CARE HEALTH INC	COM NEW	68404L201	39,151	1,790,192	SH		DFND	3	1,790,192	0	0
OSCAR HEALTH INC	CL A	687793109	14,924	694,136	SH		DFND	2	694,136	0	0
OUTSET MED INC	COM	690145107	22,844	457,060	SH		DFND	2	457,060	0	0
PACIFIC BIOSIENCES CALIF IN	COM	69404D108	57,461	1,643,159	SH		DFND	2	1,643,159	0	0
PENUMBRA INC	COM	70975L107	49,913	182,125	SH		DFND	2	182,125	0	0
PERKINELMER INC	COM	714046109	340	2,200	SH		DFND	2	2,200	0	0
PHREESIA INC	COM	71944F106	38,162	622,542	SH		DFND	2	622,542	0	0
POOL CORP	COM	73278L105	413	900	SH		DFND	2	900	0	0
PRIVIA HEALTH GROUP INC	COM	74276R102	23,294	525,000	SH		DFND	2	525,000	0	0
PULMONX CORP	COM	745848101	7,788	176,510	SH		DFND	2	176,510	0	0
QUANTERIX CORP	COM	74766Q101	37,414	637,815	SH		DFND	2	637,815	0	0
RADIUS HEALTH INC	COM NEW	750469207	1,381	75,700	SH		DFND	2	75,700	0	0
RADIUS HEALTH INC	COM NEW	750469207	135,992	7,455,714	SH		DFND	1,2	7,455,714	0	0
RECURSION PHARMACEUTICALS IN	CL A	75629V104	730	20,000	SH		DFND	2	20,000	0	0
REGENERON PHARMACEUTICALS	COM	75886F107	59,015	105,660	SH		DFND	2	105,660	0	0
RELAY THERAPEUTICS INC	COM	75943R102	732	20,000	SH		DFND	2	20,000	0	0
RELAY THERAPEUTICS INC	COM	75943R102	95,901	2,620,962	SH		DFND	1,2	2,620,962	0	0
RESMED INC	COM	761152107	21,730	88,145	SH		DFND	2	88,145	0	0
REVOLUTION MEDICINES INC	COM	76155X100	1,577	49,700	SH		DFND	2	49,700	0	0
REVOLUTION MEDICINES INC	COM	76155X100	57,294	1,805,105	SH		DFND	1,2	1,805,105	0	0
S&P GLOBAL INC	COM	78409V104	493	1,200	SH		DFND	2	1,200	0	0
SAGE THERAPEUTICS INC	COM	78667J108	2,221	39,100	SH		DFND	2	39,100	0	0
SAGE THERAPEUTICS INC	COM	78667J108	132,089	2,325,104	SH		DFND	1,2	2,325,104	0	0
SANOFI	SPONSORED ADR	80105N105	3,581	68,000	SH		DFND	2	68,000	0	0
SCHOLAR ROCK HLDG CORP	COM	80706P103	650	22,500	SH		DFND	2	22,500	0	0
SCHOLAR ROCK HLDG CORP	COM	80706P103	65,751	2,275,125	SH		DFND	1,2	2,275,125	0	0
SEAGEN INC	COM	81181C104	4,342	27,500	SH		DFND	2	27,500	0	0
SEER INC	COM CL A	81578P106	4,462	136,133	SH		DFND	2	136,133	0	0
SENSATA TECHNOLOGIES HLDNG PL	SHS	G8060N102	342	5,900	SH		DFND	2	5,900	0	0
SERVICE CORP INTL	COM	817565104	348	6,500	SH		DFND	2	6,500	0	0
SHOCKWAVE MED INC	COM	82489T104	98,074	516,915	SH		DFND	2	516,915	0	0
SIGNIFY HEALTH INC	CL A COM	82671G100	6,086	200,000	SH		DFND	2	200,000	0	0
SILK RD MED INC	COM	82710M100	19,895	415,683	SH		DFND	2	415,683	0	0
SILK RD MED INC	COM	82710M100	42,025	878,076	SH		DFND	3	878,076	0	0
SKYWORKS SOLUTIONS INC	COM	83088M102	403	2,100	SH		DFND	2	2,100	0	0
SPOTIFY TECHNOLOGY SA	SHS	L8681T102	303	1,100	SH		DFND	2	1,100	0	0
STARBUCKS CORP	COM	855244109	362	3,234	SH		DFND	2	3,234	0	0
STONECO LTD	COM CL A	G85158106	288	4,300	SH		DFND	2	4,300	0	0
STRYKER CORPORATION	COM	863667101	89,481	344,514	SH		DFND	2	344,514	0	0
SYNEOS HEALTH INC	CL A	87166B102	6,309	70,500	SH		DFND	2	70,500	0	0
TANDEM DIABETES CARE INC	COM NEW	875372203	53,392	548,173	SH		DFND	2	548,173	0	0
TANDEM DIABETES CARE INC	COM NEW	875372203	45,992	472,195	SH		DFND	3	472,195	0	0
TELADOC HEALTH INC	COM	87918A105	42,894	257,948	SH		DFND	2	257,948	0	0
TELEFLEX INCORPORATED	COM	879369106	40,244	100,161	SH		DFND	2	100,161	0	0
THERMO FISHER SCIENTIFIC INC	COM	883556102	21,175	41,974	SH		DFND	2	41,974	0	0
TRADEWEB MKTS INC	CL A	892672106	440	5,200	SH		DFND	2	5,200	0	0
TRANSMEDICS GROUP INC	COM	89377M109	24,221	729,989	SH		DFND	2	729,989	0	0
TRANSUNION	COM	89400J107	406	3,696	SH		DFND	2	3,696	0	0
TRIMBLE INC	COM	896239100	393	4,800	SH		DFND	2	4,800	0	0
TRIP COM GROUP LTD	ADS	89677Q107	355	10,000	SH		DFND	2	10,000	0	0
TYLER TECHNOLOGIES INC	COM	902252105	362	800	SH		DFND	2	800	0	0
ULTA BEAUTY INC	COM	90384S303	380	1,100	SH		DFND	2	1,100	0	0
ULTRAGENYX PHARMACEUTICAL IN	COM	90400D108	2,040	21,400	SH		DFND	2	21,400	0	0
UNITEDHEALTH GROUP INC	COM	91324P102	88,192	220,238	SH		DFND	2	220,238	0	0
UNITEDHEALTH GROUP INC	COM	91324P102	49,179	122,813	SH		DFND	3	122,813	0	0
UNIVERSAL DISPLAY CORP	COM	91347P105	303	1,365	SH		DFND	2	1,365	0	0
VEEVA SYS INC	CL A COM	922475108	53,685	172,647	SH		DFND	2	172,647	0	0
VERISIGN INC	COM	92343E102	387	1,700	SH		DFND	2	1,700	0	0
VERISK ANALYTICS INC	COM	92345Y106	304	1,739	SH		DFND	2	1,739	0	0
VERTEX PHARMACEUTICALS INC	COM	92532F100	48,230	239,200	SH		DFND	2	239,200	0	0
VERTEX PHARMACEUTICALS INC	COM	92532F100	89,623	444,494	SH		DFND	3	444,494	0	0
VERTEX PHARMACEUTICALS INC	COM	92532F100	211,712	1,050,000	SH		DFND	1,2	1,050,000	0	0
VOCERA COMMUNICATONS INC	COM	92857F107	19,921	499,912	SH		DFND	2	499,912	0	0
VOCERA COMMUNICATONS INC	COM	92857F107	6,094	152,920	SH		DFND	3	152,920	0	0
WABTEC	COM	929740108	346	4,200	SH		DFND	2	4,200	0	0
WATSCO INC	COM	942622200	373	1,300	SH		DFND	2	1,300	0	0
WAVE LIFE SCIENCES LTD	SHS	Y95308105	17,335	2,602,858	SH		DFND	1,2	2,602,858	0	0
XENCOR INC	COM	98401F105	1,831	53,100	SH		DFND	2	53,100	0	0
ZAI LAB LTD	ADR	98887Q104	21,593	122,000	SH		DFND	2	122,000	0	0
ZIMMER BIOMET HOLDINGS INC	COM	98956P102	45,043	280,082	SH		DFND	2	280,082	0	0
ZOETIS INC	CL A	98978V103	1,323	7,100	SH		DFND	2	7,100	0	0