Bellevue (BLVGF) 13F-HR Quarterly holdings report by institutional manager

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL

OMB Number:		3235-0006
Expires:	Oct 31, 2018
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COLUMN 1	COLUMN 2	COLUMN 3	COLUMN 4	COLUMN 5			COLUMN 6	COLUMN 7	COLUMN 8
			VALUE	SHRS OR	SH/	PUT/	INVESTMENT	OTHER	VOTING AUTHORITY
NAME OF ISSUER	TITLE OF CLASS	CUSIP	(x$1000)	PRN AMT	PRN	CALL	DISCRETION	MANAGER	SOLE	SHARED	NONE
1LIFE HEALTHCARE INC	COM	68269G107	6,556	836,190	SH		DFND	2	836,190	0	0
10X GENOMICS INC	CL A COM	88025U109	11,737	259,371	SH		DFND	2	259,371	0	0
ABBOTT LABS	COM	002824100	170,994	1,573,807	SH		DFND	2	1,573,807	0	0
ABBVIE INC	COM	00287Y109	124	808	SH		DFND	2	808	0	0
ABIOMED INC	COM	003654100	41,955	169,509	SH		DFND	2	169,509	0	0
ACCOLADE INC	COM	00437E102	5,095	688,479	SH		DFND	2	688,479	0	0
ACCOLADE INC	COM	00437E102	21,803	2,946,407	SH		DFND	3	2,946,407	0	0
ADAPTIVE BIOTECHNOLOGIES COR	COM	00650F109	28,631	3,539,055	SH		DFND	3	3,539,055	0	0
AGIOS PHARMACEUTICALS INC	COM	00847X104	709	32,000	SH		DFND	2	32,000	0	0
AGIOS PHARMACEUTICALS INC	COM	00847X104	89,363	4,030,792	SH		DFND	1,2	4,030,792	0	0
ALIGN TECHNOLOGY INC	COM	016255101	32,007	135,240	SH		DFND	2	135,240	0	0
ALKERMES PLC	SHS	G01767105	3,193	107,200	SH		DFND	2	107,200	0	0
ALNYLAM PHARMACEUTICALS INC	COM	02043Q107	4,267	29,257	SH		DFND	2	29,257	0	0
ALNYLAM PHARMACEUTICALS INC	COM	02043Q107	150,069	1,028,929	SH		DFND	1,2	1,028,929	0	0
ALPHABET INC	CAP STK CL C	02079K107	656	300	SH		DFND	2	300	0	0
AMEDISYS INC	COM	023436108	8,023	76,322	SH		DFND	2	76,322	0	0
AMEDISYS INC	COM	023436108	53,488	508,832	SH		DFND	3	508,832	0	0
AMERICAN WELL CORP	CL A	03044L105	7,645	1,769,703	SH		DFND	2	1,769,703	0	0
AMERISOURCEBERGEN CORP	COM	03073E105	1,839	13,000	SH		DFND	2	13,000	0	0
AMGEN INC	COM	031162100	12,398	50,959	SH		DFND	2	50,959	0	0
APELLIS PHARMACEUTICALS INC	COM	03753U106	1,379	30,500	SH		DFND	2	30,500	0	0
APELLIS PHARMACEUTICALS INC	COM	03753U106	53,175	1,175,922	SH		DFND	3	1,175,922	0	0
ARCTURUS THERAPEUTICS HLDGS	COM	03969T109	623	39,550	SH		DFND	2	39,550	0	0
ARCUS BIOSCIENCES INC	COM	03969F109	2,283	90,100	SH		DFND	2	90,100	0	0
ARGENX SE	SPONSORED ADR	04016X101	11,859	31,300	SH		DFND	2	31,300	0	0
ARGENX SE	SPONSORED ADR	04016X101	337,782	902,503	SH		DFND	1,2	902,503	0	0
ARVINAS INC	COM	04335A105	2,494	59,250	SH		DFND	2	59,250	0	0
ARVINAS INC	COM	04335A105	86,917	2,065,026	SH		DFND	1,2	2,065,026	0	0
ASTRAZENECA PLC	SPONSORED ADR	046353108	5,748	87,000	SH		DFND	2	87,000	0	0
ATRICURE INC	COM	04963C209	26,228	641,896	SH		DFND	3	641,896	0	0
AURINIA PHARMACEUTICALS INC	COM	05156V102	26,848	2,671,413	SH		DFND	3	2,671,413	0	0
AVALARA INC	COM	05338G106	92	1,300	SH		DFND	2	1,300	0	0
AVANTOR INC	COM	05352A100	15,644	503,007	SH		DFND	2	503,007	0	0
AXONICS INC	COM	05465P101	64,720	1,142,056	SH		DFND	2	1,142,056	0	0
AXONICS INC	COM	05465P101	66,406	1,171,796	SH		DFND	3	1,171,796	0	0
AXSOME THERAPEUTICS INC	COM	05464T104	31,297	817,141	SH		DFND	3	817,141	0	0
BAXTER INTL INC	COM	071813109	29,406	457,819	SH		DFND	2	457,819	0	0
BEAM THERAPEUTICS INC	COM	07373V105	174	4,500	SH		DFND	2	4,500	0	0
BEAM THERAPEUTICS INC	COM	07373V105	21,992	568,121	SH		DFND	1,2	568,121	0	0
BECTON DICKINSON & CO	COM	075887109	84,555	342,982	SH		DFND	2	342,982	0	0
BERKELEY LTS INC	COM	084310101	1,914	385,014	SH		DFND	2	385,014	0	0
BICYCLE THERAPEUTICS PLC	SPONSORED ADS	088786108	1,416	84,400	SH		DFND	2	84,400	0	0
BIOGEN INC	COM	09062X103	4,456	21,850	SH		DFND	2	21,850	0	0
BIONTECH SE	SPONSORED ADS	09075V102	22,544	151,200	SH		DFND	2	151,200	0	0
BIOMARIN PHARMACEUTICAL INC	COM	09061G101	6,112	73,753	SH		DFND	2	73,753	0	0
BIO RAD LABS INC	CL A	090572207	45,125	91,161	SH		DFND	3	91,161	0	0
BLACK DIAMOND THERAPEUTICS I	COM	09203E105	57	23,000	SH		DFND	2	23,000	0	0
BLACK DIAMOND THERAPEUTICS I	COM	09203E105	11,548	4,694,113	SH		DFND	1,2	4,694,113	0	0
BOSTON SCIENTIFIC CORP	COM	101137107	143,496	3,850,171	SH		DFND	2	3,850,171	0	0
BRISTOL-MYERS SQUIBB CO	COM	110122108	1,918	24,907	SH		DFND	2	24,907	0	0
CAREDX INC	COM	14167L103	54,506	2,537,524	SH		DFND	3	2,537,524	0	0
CARIBOU BIOSCIENCES INC	COM	142038108	382	70,300	SH		DFND	2	70,300	0	0
CASTLE BIOSCIENCES INC	COM	14843C105	20,656	941,059	SH		DFND	3	941,059	0	0
CELLDEX THERAPEUTICS	COM NEW	15117B202	24,938	925,000	SH		DFND	1,2	925,000	0	0
CENTENE CORP DEL	COM	15135B101	46,189	545,903	SH		DFND	2	545,903	0	0
CHARLES RIV LABS INTL INC	COM	159864107	49,442	231,069	SH		DFND	3	231,069	0	0
CIGNA CORP NEW	COM	125523100	51,032	193,657	SH		DFND	2	193,657	0	0
COOPER COS INC	COM NEW	216648402	25,513	81,479	SH		DFND	2	81,479	0	0
CRISPR THERAPEUTICS AG	NAMEN AKT	H17182108	2,030	33,400	SH		DFND	2	33,400	0	0
CRISPR THERAPEUTICS AG	NAMEN AKT	H17182108	54,001	888,605	SH		DFND	1,2	888,605	0	0
CVS HEALTH CORP	COM	126650100	21,233	229,153	SH		DFND	2	229,153	0	0
CYTOKINETICS INC	COM NEW	23282W605	2,609	66,400	SH		DFND	2	66,400	0	0
DANAHER CORPORATION	COM	235851102	92,290	364,036	SH		DFND	2	364,036	0	0
DEXCOM INC	COM	252131107	69,202	928,508	SH		DFND	2	928,508	0	0
DOLBY LABORATORIES INC	COM CL A	25659T107	114	1,600	SH		DFND	2	1,600	0	0
DOXIMITY INC	CL A	26622P107	4,747	136,322	SH		DFND	2	136,322	0	0
DR REDDYS LABS LTD	ADR	256135203	687	12,400	SH		DFND	2	12,400	0	0
EDWARDS LIFESCIENCES CORP	COM	28176E108	96,101	1,010,627	SH		DFND	2	1,010,627	0	0
ELEVANCE HEALTH INC	COM	036752103	52,174	108,114	SH		DFND	2	108,114	0	0
ELEVANCE HEALTH INC	COM	036752103	48,444	100,386	SH		DFND	3	100,386	0	0
ENVISTA HOLDINGS CORPORATION	COM	29415F104	19	484	SH		DFND	2	484	0	0
EQUINIX INC	COM	29444U700	26	40	SH		DFND	2	40	0	0
ESPERION THERAPEUTICS INC NE	COM	29664W105	262	41,200	SH		DFND	2	41,200	0	0
ESPERION THERAPEUTICS INC NE	COM	29664W105	26,674	4,194,064	SH		DFND	1,2	4,194,064	0	0
ESSA PHARMA INC	COM NEW	29668H708	60	19,000	SH		DFND	2	19,000	0	0
ESSA PHARMA INC	COM NEW	29668H708	15,721	4,990,714	SH		DFND	1,2	4,990,714	0	0
EVERTEC INC	COM	30040P103	27	739	SH		DFND	2	739	0	0
EVOLENT HEALTH INC	CL A	30050B101	25,404	827,214	SH		DFND	2	827,214	0	0
EVOLENT HEALTH INC	CL A	30050B101	36,585	1,191,307	SH		DFND	3	1,191,307	0	0
EXACT SCIENCES CORP	COM	30063P105	29,859	758,023	SH		DFND	3	758,023	0	0
EXELIXIS INC	COM	30161Q104	500	24,000	SH		DFND	2	24,000	0	0
EXELIXIS INC	COM	30161Q104	55,267	2,654,500	SH		DFND	1,2	2,654,500	0	0
FATE THERAPEUTICS INC	COM	31189P102	2,269	91,550	SH		DFND	2	91,550	0	0
FATE THERAPEUTICS INC	COM	31189P102	85,703	3,458,536	SH		DFND	1,2	3,458,536	0	0
GENERATION BIO CO	COM	37148K100	125	19,000	SH		DFND	2	19,000	0	0
GENERATION BIO CO	COM	37148K100	23,670	3,608,280	SH		DFND	1,2	3,608,280	0	0
GILEAD SCIENCES INC	COM	375558103	4,662	75,426	SH		DFND	2	75,426	0	0
GLOBUS MED INC	CL A	379577208	36,866	656,681	SH		DFND	2	656,681	0	0
GRUPO AEROPORTUARIO DEL SURE	SPON ADR SER B	40051E202	27	135	SH		DFND	2	135	0	0
GUARDANT HEALTH INC	COM	40131M109	2,847	70,580	SH		DFND	2	70,580	0	0
HALOZYME THERAPEUTICS INC	COM	40637H109	42,737	971,300	SH		DFND	2	971,300	0	0
HARMONY BIOSCIENCES HLDGS IN	COM	413197104	34,240	702,068	SH		DFND	2	702,068	0	0
HCA HEALTHCARE INC	COM	40412C101	49,203	292,771	SH		DFND	2	292,771	0	0
HEALTH CATALYST INC	COM	42225T107	6,153	424,611	SH		DFND	2	424,611	0	0
HOLOGIC INC	COM	436440101	18,768	270,825	SH		DFND	2	270,825	0	0
HOMOLOGY MEDICINES INC	COM	438083107	3,196	1,622,522	SH		DFND	1,2	1,622,522	0	0
HORIZON THERAPEUTICS PUB L	SHS	G46188101	26,914	337,434	SH		DFND	2	337,434	0	0
HUMANA INC	COM	444859102	68,015	145,309	SH		DFND	2	145,309	0	0
HUTCHMED CHINA LTD	SPONSORED ADS	44842L103	21,359	1,756,307	SH		DFND	3	1,756,307	0	0
IDEXX LABS INC	COM	45168D104	40,605	115,773	SH		DFND	2	115,773	0	0
ILLUMINA INC	COM	452327109	16,015	86,867	SH		DFND	2	86,867	0	0
INCYTE CORP	COM	45337C102	6,252	82,300	SH		DFND	2	82,300	0	0
INCYTE CORP	COM	45337C102	204,441	2,691,077	SH		DFND	1,2	2,691,077	0	0
INFOSYS LTD	SPONSORED ADR	456788108	21	1,130	SH		DFND	2	1,130	0	0
INHIBRX INC	COM	45720L107	869	76,600	SH		DFND	2	76,600	0	0
INSMED INC	COM PAR $.01	457669307	71,417	3,621,562	SH		DFND	3	3,621,562	0	0
INSPIRE MED SYS INC	COM	457730109	74,357	407,057	SH		DFND	2	407,057	0	0
INSULET CORP	COM	45784P101	84,198	386,335	SH		DFND	2	386,335	0	0
INTELLIA THERAPEUTICS INC	COM	45826J105	817	15,794	SH		DFND	2	15,794	0	0
INTRA-CELLULAR THERAPIES INC	COM	46116X101	3,305	57,900	SH		DFND	2	57,900	0	0
INTRA-CELLULAR THERAPIES INC	COM	46116X101	187,878	3,291,479	SH		DFND	1,2	3,291,479	0	0
INTUITIVE SURGICAL INC	COM NEW	46120E602	151,575	755,192	SH		DFND	2	755,192	0	0
INTUITIVE SURGICAL INC	COM NEW	46120E602	30,941	154,156	SH		DFND	3	154,156	0	0
IONIS PHARMACEUTICALS INC	COM	462222100	8,718	235,500	SH		DFND	2	235,500	0	0
IONIS PHARMACEUTICALS INC	COM	462222100	353,209	9,541,028	SH		DFND	1,2	9,541,028	0	0
IPG PHOTONICS CORP	COM	44980X109	99	1,050	SH		DFND	2	1,050	0	0
IQVIA HLDGS INC	COM	46266C105	36,584	168,598	SH		DFND	2	168,598	0	0
ISHARES TR	MSCI CHINA ETF	46429B671	229	4,100	SH		DFND	2	4,100	0	0
JAZZ PHARMACEUTICALS PLC	SHS USD	G50871105	41,882	268,456	SH		DFND	2	268,456	0	0
JAZZ PHARMACEUTICALS PLC	SHS USD	G50871105	101,321	649,451	SH		DFND	3	649,451	0	0
JOHNSON & JOHNSON	COM	478160104	5,133	28,914	SH		DFND	2	28,914	0	0
JUMIA TECHNOLOGIES AG	SPONSORED ADS	48138M105	109	18,000	SH		DFND	2	18,000	0	0
KEZAR LIFE SCIENCES INC	COM	49372L100	289	35,000	SH		DFND	2	35,000	0	0
KEZAR LIFE SCIENCES INC	COM	49372L100	24,810	3,000,000	SH		DFND	1,2	3,000,000	0	0
KOSMOS ENERGY LTD	COM	500688106	1,970	318,300	SH		DFND	2	318,300	0	0
KRYSTAL BIOTECH INC	COM	501147102	880	13,400	SH		DFND	2	13,400	0	0
KURA ONCOLOGY INC	COM	50127T109	1,168	63,700	SH		DFND	2	63,700	0	0
LABORATORY CORP AMER HLDGS	COM NEW	50540R409	996	4,250	SH		DFND	2	4,250	0	0
LAUDER ESTEE COS INC	CL A	518439104	343	1,348	SH		DFND	2	1,348	0	0
LEGEND BIOTECH CORP	SPONSORED ADS	52490G102	34,674	630,439	SH		DFND	2	630,439	0	0
LILLY ELI & CO	COM	532457108	314	969	SH		DFND	2	969	0	0
MACROGENICS INC	COM	556099109	147	49,950	SH		DFND	2	49,950	0	0
MACROGENICS INC	COM	556099109	21,463	7,275,564	SH		DFND	1,2	7,275,564	0	0
MARKETAXESS HLDGS INC	COM	57060D108	169	662	SH		DFND	2	662	0	0
MCKESSON CORP	COM	58155Q103	828	2,537	SH		DFND	2	2,537	0	0
MEDTRONIC PLC	SHS	G5960L103	57,934	645,506	SH		DFND	2	645,506	0	0
MERCADOLIBRE INC	COM	58733R102	108	170	SH		DFND	2	170	0	0
MERCK & CO. INC	COM	58933Y105	88	964	SH		DFND	2	964	0	0
MERSANA THERAPEUTICS INC	COM	59045L106	134	29,000	SH		DFND	2	29,000	0	0
MERSANA THERAPEUTICS INC	COM	59045L106	17,862	3,866,200	SH		DFND	1,2	3,866,200	0	0
MODERNA INC	COM	60770K107	6,485	45,400	SH		DFND	2	45,400	0	0
MODERNA INC	COM	60770K107	218,839	1,531,951	SH		DFND	1,2	1,531,951	0	0
MOLECULAR TEMPLATES INC	COM	608550109	78	86,000	SH		DFND	2	86,000	0	0
MOLECULAR TEMPLATES INC	COM	608550109	10,203	11,192,003	SH		DFND	1,2	11,192,003	0	0
MOLINA HEALTHCARE INC	COM	60855R100	69,431	248,313	SH		DFND	2	248,313	0	0
MYOVANT SCIENCES LTD	COM	G637AM102	584	47,000	SH		DFND	2	47,000	0	0
MYOVANT SCIENCES LTD	COM	G637AM102	72,997	5,872,639	SH		DFND	1,2	5,872,639	0	0
NEKTAR THERAPEUTICS	COM	640268108	109	28,800	SH		DFND	2	28,800	0	0
NEUROCRINE BIOSCIENCES INC	COM	64125C109	4,471	45,868	SH		DFND	2	45,868	0	0
NEUROCRINE BIOSCIENCES INC	COM	64125C109	272,792	2,798,437	SH		DFND	1,2	2,798,437	0	0
NEUROPACE INC	COM	641288105	2,514	507,930	SH		DFND	2	507,930	0	0
NEVRO CORP	COM	64157F103	11,630	265,339	SH		DFND	2	265,339	0	0
NOVOCURE LTD	ORD SHS	G6674U108	1,758	25,300	SH		DFND	2	25,300	0	0
OLINK HLDG AB	SPONSORED ADS	680710100	3,576	235,273	SH		DFND	2	235,273	0	0
OMNICELL COM	COM	68213N109	48,437	425,823	SH		DFND	2	425,823	0	0
OPTHEA LTD	SPONSORED ADS	68386J208	296	47,000	SH		DFND	2	47,000	0	0
OPTION CARE HEALTH INC	COM NEW	68404L201	80,237	2,887,259	SH		DFND	3	2,887,259	0	0
OUTSET MED INC	COM	690145107	10,558	710,480	SH		DFND	2	710,480	0	0
OUTSET MED INC	COM	690145107	24,017	1,616,238	SH		DFND	3	1,616,238	0	0
PACIFIC BIOSCIENCES CALIF IN	COM	69404D108	7,049	1,594,774	SH		DFND	2	1,594,774	0	0
PACIFIC BIOSCIENCES CALIF IN	COM	69404D108	19,300	4,366,455	SH		DFND	3	4,366,455	0	0
PACIRA BIOSCIENCES INC	COM	695127100	3,028	51,936	SH		DFND	2	51,936	0	0
PENUMBRA INC	COM	70975L107	23,981	192,588	SH		DFND	2	192,588	0	0
PFIZER INC	COM	717081103	43,815	835,684	SH		DFND	2	835,684	0	0
PHREESIA INC	COM	71944F106	17,011	680,153	SH		DFND	2	680,153	0	0
PRIVIA HEALTH GROUP INC	COM	74276R102	15,139	519,876	SH		DFND	2	519,876	0	0
PROCEPT BIOROBOTICS CORP	COM	74276L105	19,463	595,380	SH		DFND	2	595,380	0	0
PULMONX CORP	COM	745848101	2,552	173,336	SH		DFND	2	173,336	0	0
RADIUS HEALTH INC	COM NEW	750469207	653	63,000	SH		DFND	2	63,000	0	0
RADIUS HEALTH INC	COM NEW	750469207	90,567	8,733,538	SH		DFND	1,2	8,733,538	0	0
REGENERON PHARMACEUTICALS	COM	75886F107	10,479	17,727	SH		DFND	2	17,727	0	0
RELAY THERAPEUTICS INC	COM	75943R102	913	54,500	SH		DFND	2	54,500	0	0
RELAY THERAPEUTICS INC	COM	75943R102	66,628	3,977,762	SH		DFND	1,2	3,977,762	0	0
RELMADA THERAPEUTICS INC	COM	75955J402	665	35,000	SH		DFND	2	35,000	0	0
RESMED INC	COM	761152107	17,790	84,865	SH		DFND	2	84,865	0	0
REVOLUTION MEDICINES INC	COM	76155X100	1,573	80,700	SH		DFND	2	80,700	0	0
REVOLUTION MEDICINES INC	COM	76155X100	64,367	3,302,562	SH		DFND	1,2	3,302,562	0	0
SAGE THERAPEUTICS INC	COM	78667J108	740	22,900	SH		DFND	2	22,900	0	0
SAGE THERAPEUTICS INC	COM	78667J108	95,294	2,950,278	SH		DFND	1,2	2,950,278	0	0
SANOFI	SPONSORED ADR	80105N105	2,116	42,300	SH		DFND	2	42,300	0	0
SAREPTA THERAPEUTICS INC	COM	803607100	31	409	SH		DFND	2	409	0	0
SAREPTA THERAPEUTICS INC	COM	803607100	85,383	1,139,046	SH		DFND	3	1,139,046	0	0
SCHOLAR ROCK HLDG CORP	COM	80706P103	106	19,300	SH		DFND	2	19,300	0	0
SCHOLAR ROCK HLDG CORP	COM	80706P103	11,709	2,132,725	SH		DFND	1,2	2,132,725	0	0
SEAGEN INC	COM	81181C104	8,737	49,376	SH		DFND	2	49,376	0	0
SEER INC	COM CL A	81578P106	1,218	136,133	SH		DFND	2	136,133	0	0
SHOCKWAVE MED INC	COM	82489T104	70,867	370,699	SH		DFND	2	370,699	0	0
SIGHT SCIENCES INC	COM	82657M105	2,649	294,606	SH		DFND	2	294,606	0	0
SILENCE THERAPEUTICS PLC	ADS	82686Q101	361	30,483	SH		DFND	2	30,483	0	0
SILK RD MED INC	COM	82710M100	38,111	1,047,286	SH		DFND	3	1,047,286	0	0
SKYWORKS SOLUTIONS INC	COM	83088M102	195	2,100	SH		DFND	2	2,100	0	0
STRYKER CORPORATION	COM	863667101	95,016	477,634	SH		DFND	2	477,634	0	0
SUPERNUS PHARMACEUTICALS INC	COM	868459108	2,383	82,400	SH		DFND	2	82,400	0	0
TANDEM DIABETES CARE INC	COM NEW	875372203	33,267	562,030	SH		DFND	2	562,030	0	0
TANDEM DIABETES CARE INC	COM NEW	875372203	44,620	753,843	SH		DFND	3	753,843	0	0
TELADOC HEALTH INC	COM	87918A105	13,819	416,112	SH		DFND	2	416,112	0	0
TELEFLEX INCORPORATED	COM	879369106	23,598	95,984	SH		DFND	2	95,984	0	0
THERMO FISHER SCIENTIFIC INC	COM	883556102	39,017	71,818	SH		DFND	2	71,818	0	0
TRANSMEDICS GROUP INC	COM	89377M109	18,237	579,887	SH		DFND	2	579,887	0	0
ULTRAGENYX PHARMACEUTICAL IN	COM	90400D108	1,849	31,000	SH		DFND	2	31,000	0	0
UNITEDHEALTH GROUP INC	COM	91324P102	85,820	167,086	SH		DFND	2	167,086	0	0
UNITEDHEALTH GROUP INC	COM	91324P102	69,318	134,958	SH		DFND	3	134,958	0	0
UNITED THERAPEUTICS CORP DEL	COM	91307C102	45	193	SH		DFND	2	193	0	0
VANECK ETF TRUST	GOLD MINERS ETF	92189F106	367	13,400	SH		DFND	2	13,400	0	0
VANECK ETF TRUST	JUNIOR GOLD MINE	92189F791	160	5,000	SH		DFND	2	5,000	0	0
VEEVA SYS INC	CL A COM	922475108	33,424	168,776	SH		DFND	2	168,776	0	0
VERTEX PHARMACEUTICALS INC	COM	92532F100	24,327	86,332	SH		DFND	2	86,332	0	0
VERTEX PHARMACEUTICALS INC	COM	92532F100	39,248	139,281	SH		DFND	3	139,281	0	0
VERTEX PHARMACEUTICALS INC	COM	92532F100	267,848	950,523	SH		DFND	1,2	950,523	0	0
VIRIDIAN THERAPEUTICS INC	COM	92790C104	567	49,000	SH		DFND	2	49,000	0	0
WAVE LIFE SCIENCES LTD	SHS	Y95308105	14,607	4,494,458	SH		DFND	1,2	4,494,458	0	0
XENCOR INC	COM	98401F105	725	26,500	SH		DFND	2	26,500	0	0
ZIMMER BIOMET HOLDINGS INC	COM	98956P102	27,955	266,087	SH		DFND	2	266,087	0	0
ZOETIS INC	CL A	98978V103	86	503	SH		DFND	2	503	0	0