Motif Bio plc
125 Park Avenue
25 Floor, Suite 2622
New York, NY 10011
United States
August 4, 2016
VIA EDGAR
Securities and Exchange Commission
Division of Corporation Finance
100 F Street, N.E.
Washington, D.C. 20549
Attn: Suzanne Hayes
Re: Motif Bio plc
Registration Statement on Form F-1
File No. 333-212491
Dear Ms. Hayes:
Motif Bio plc (the “Company”) hereby respectfully withdraws its request for acceleration of the effectiveness of the above-referenced Registration Statement on Form F-1 set forth in a letter, dated August 3, 2016 from the Company.
Should you have any questions this request, please do not hesitate to contact Aron Izower of Reed Smith LLP by telephone at (212) 549-0393.
| Very truly yours, |
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| MOTIF BIO PLC |
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| /s/ Graham Lumsden |
| Graham Lumsden |
| Chief Executive Office and Executive Director |
cc: | Aron Izower, Esq. (Reed Smith LLP) |
| Wendy Grasso, Esq. (Reed Smith LLP) |
| Anna Pinedo, Esq. (Morrison & Foerster LLP) |
| Brian Hirshberg, Esq. (Morrison & Foerster LLP) |
