MOTIF BIO PLC
125 Park Avenue
25th Floor
New York, New York 10011
(646) 880-3050
January 29, 2018
VIA EDGAR
United States Securities and Exchange Commission
Division of Corporation Finance
100 F. Street, N.E.
Washington, D.C. 20549-4561
Attn: | Irene Paik |
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| Re: | Motif Bio plc |
| | Registration Statement on Form F-3 |
| | Filed January 18, 2018 |
| | File No. 333-222614 |
Dear Ms. Paik:
Motif Bio plc, a company formed under the laws of England and Wales (the “Company”), hereby requests that the effective date for the Registration Statement referred to above be accelerated so that it will be declared effective at 4 p.m. Eastern Time, on January 31, 2018, or as soon as practicable thereafter, unless we or our outside counsel, DLA Piper LLP (US), request by telephone that such Registration Statement be declared effective at some other time, pursuant to Rule 461 under the Securities Act of 1933, as amended.
The Company acknowledges that: (i) should the Securities and Exchange Commission (the “Commission”) or the staff of the Commission, acting pursuant to delegated authority, declare the filing effective, such declaration does not foreclose the Commission from taking any action with respect to the filing; (ii) the action of the Commission or the staff of the Commission, acting pursuant to delegated authority, in declaring the filing effective, does not relieve the Company from its full responsibility for the adequacy and accuracy of the disclosure in the filing; and (iii) the Company may not assert staff comments and the declaration of effectiveness as a defense in any proceeding initiated by the Commission or any person under the federal securities laws of the United States.
It would be appreciated if, as soon as the Registration Statement is declared effective, you would so inform Fahd M.T. Riaz, Esq. of DLA Piper LLP (US) at (215) 656-3316.
| MOTIF BIO PLC |
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| By: | /s/ Graham Lumsden |
| | Name: Graham Lumsden |
| | Title: Chief Executive Officer |
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cc: | Fahd M.T. Riaz, Esq., DLA Piper LLP (US) | |
| Andrew P. Gilbert, Esq., DLA Piper LLP (US) | |