Exhibit 23.1
![](https://capedge.com/proxy/F-3A/0001178913-19-001102/image00006.jpg)
CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
We hereby consent to the incorporation by reference in this Registration Statement on Form F-3 of Sol-Gel Technologies Ltd. of our report dated March 21, 2019 relating to the financial statements, which appears in Sol-Gel Technologies Ltd.'s Annual Report on Form 20-F for the year ended December 31, 2018. We also consent to the reference to us under the heading "Experts" in such Registration Statement.
Tel-Aviv, Israel | /s/ Kesselman & Kesselman | |
April 10, 2019 | Certified Public Accountants (Isr.) | |
A member firm of PricewaterhouseCoopers International Limited |