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Exhibit 23.1
CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
We hereby consent to the incorporation by reference in the Registration Statements on FormS-8 (No.333-226047 andNo. 333-231746) and FormS-3 (No.333-232543) of Translate Bio, Inc. of our report dated March 12, 2020 relating to the financial statements, which appears in this Annual Report on Form10-K.
/s/ PricewaterhouseCoopers LLP
Boston, Massachusetts
March 12, 2020