Exhibit 99.2

Aug 3, 2021
Dear Colleagues,
Today, we announced plans to acquire Translate Bio, and we are delighted to formally reach out and welcome you all to the Sanofi family.
As the Heads of Research and Development (John) and Vaccines (Thomas) at Sanofi, we are tremendously excited about the prospect of uniting our teams to further accelerate advances in mRNA technologies. Since our collaboration established in 2018, we have discovered a similarity of purpose, focus, and commitment — both in the areas of infectious disease and in developing novel therapeutics. Like you, we are dedicated to pushing the boundaries of science, and to making a meaningful difference in the lives of millions around the world.
In building the Sanofi pipeline, we have invested broadly in expanding our “toolbox” of modalities, and consequently our portfolio has become increasingly diverse. These include the nanobody platform that the company accessed when we brought Ablynx into the Sanofi family, as well as the synthetic biology platform we received last year when Synthorx joined us. We anticipate that adding Translate Bio’s novel and powerful mRNA platform will have significant synergies with our ongoing vaccines, immunology, oncology, and rare disease research efforts, and that in working together, we will design and deliver the next generation of transformative vaccines and therapeutics. In particular, we are excited by the opportunity to unlock key areas of mRNA vaccine innovation such as thermostability and tolerability improvements, which will be critical to delivering post-pandemic mRNA-based vaccines for use in routine immunization against a broad set of infectious diseases and across all ages.
In this regard, Sanofi is a global, diversified healthcare company with operations around the world. Our global commercial presence and established manufacturing footprint can help deliver Translate Bio’s pipeline to millions around the world, expanding the magnitude of your impact on human health.
Today marks the first step in this process. Until the deal is completed, which we expect to occur in the third quarter of 2021, subject to conditions, such as antitrust clearance and other customary requirements, Translate Bio will continue to operate as a separate company. During this time, it will be critical that you continue to advance your pipeline with the urgency that patients would expect.
In closing, we look forward to welcoming you properly to the Sanofi family and to ensuring a smooth transition for the Translate Bio teams. We are extremely excited to work with you in advancing our ambitions to transform the practice of medicine and reinvent health protection.
With our best wishes,
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John Reed, MD., Ph.D. | | Thomas Triomphe |
Global Head, Sanofi Research and Development | | Global Head, Sanofi Vaccines Global Business Unit |