
PLEASE BE SURE TO SIGN AND DATE THIS PROXY CARD AND MARK ON THE REVERSE SIDEFrequency Therapeutics, Inc. Annual Meeting of Stockholders Please make your marks like this: THE BOARD OF DIRECTORS RECOMMENDS A VOTE: FOR THE DIRECTOR IN PROPOSAL 4 AND FOR PROPOSALS 1, 2, 3, 5, 6, 7 and 8 PROPOSAL YOUR VOTE BOARD OF DIRECTORS RECOMMENDS 1. To approve the issuance of shares of common stock of Frequency Therapeutics, Inc. (“Frequency”) to the stockholders of Korro Bio, Inc. (“Korro Bio”), pursuant to the Agreement and Plan of Merger, dated as of July 14, 2023, by and among Frequency, Korro Bio and Frequency Merger Sub, Inc. (“Merger Sub”), pursuant to which Merger Sub, will merge with and into Korro Bio, with Korro Bio surviving as a wholly owned subsidiary of Frequency, and the surviving corporation of the merger (the “Merger”), and the change of control resulting from the Merger. FOR AGAINST ABSTAIN FOR 2. To approve an amendment to the Restated Certificate of Incorporation of Frequency to effect a reverse stock split of Frequency’s issued and outstanding common stock at a ratio ranging from any whole number between 1-for-25 and 1-for-50 as determined by Frequency’s board of directors in its discretion, subject to the Frequency board of directors’ authority to abandon such amendment. FOR AGAINST ABSTAIN FOR 3. To elect David L. Lucchino as a Class I director, to hold office until the annual meeting of stockholders to be held in 2026 and until his successor has been duly elected and qualified. FOR WITHHOLD FOR 4. To ratify, in a non-binding vote, the appointment of RSM US LLP as Frequency’s independent registered public accounting firm for the fiscal year ending December 31, 2023. FOR AGAINST ABSTAIN FOR 5. To approve the 2023 Stock Option and Incentive Plan. FOR AGAINST ABSTAIN FOR 6. To approve the 2023 Employee Stock Purchase Plan FOR AGAINST ABSTAIN FOR 7. To approve an adjournment of the Annual Meeting of Stockholders, if necessary, to solicit additional proxies if there are not sufficient votes in favor of Proposal Nos. 1 and 2. FOR AGAINST ABSTAIN FOR NOTE: To transact such other business as may properly come before the Annual Meeting of Stockholders or any continuation, postponement or adjournment thereof.