Exhibit 5.1
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Office: +852 2801 6066
Mobile: +852 9718 8740
Email: rthorp@tta.lawyer
Zai Lab Limited
Harbour Place 2nd Floor
103 South Church Street
P.O. Box 472, George Town
Grand Cayman KYI-1106
Cayman Islands
15 November 2024
Dear Sirs
Zai Lab Limited
We have acted as Cayman Islands legal advisers to Zai Lab Limited (the “Company”) in connection with the Company’s registration statement on Form S-3ASR (File No. 333-278843) (the “Base Prospectus”), filed with the United States Securities and Exchange Commission (the “Commission”) under the United States Securities Act of 1933 (the “Act”) on April 19, 2024, and the final prospectus supplement dated November 14, 2024, (including all amendments or supplements thereto (together with the Base Prospectus, the “Registration Statement”) related to the offering by the Company of American Depositary Shares representing ten of its ordinary shares, par value of US$0.000006 per share (the “Shares”). This opinion is given in accordance with the terms of the Legal Matters section of the Registration Statement.
For the purposes of this opinion, we have reviewed originals, copies, drafts or conformed copies of the documents listed in Schedule 1 to this opinion, being all of the documents necessary to form our opinion. Defined terms shall have the meanings set out in Schedule 1 or in the Registration Statement.
The following opinions are given only as to and based on circumstances and matters of fact existing at the date hereof and as to the laws of the Cayman Islands as the same are in force at the date hereof. In giving this opinion, we have relied upon the completeness and accuracy (and assumed the continuing completeness and accuracy as at the date hereof) of the Certificate of Good Standing and the Director’s Certificate, as to matters of fact, without further verification and have assumed that copy documents or drafts of documents provided to us are true and complete copies of, or in the final forms of, the originals.
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