Exhibit (e)
Rule 466 Certification
The depositary, Citibank, N.A., represents and certifies the following:
| (i) | That it had previously filed a registration statement on Form F-6 (Registration No. 333-220256) with respect to Zai Lab Limited, which the U.S. Securities and Exchange Commission declared effective, with terms of deposit identical to the terms of deposit of this Form F-6 Registration Statement; and |
| (ii) | That its ability to designate the date and time of effectiveness under Rule 466 has not been suspended. |
| CITIBANK, N.A., as Depositary | |||
| By: | /s/ Joseph Connor | ||
| Name: | Joseph Connor | ||
| Title: | Attorney-in-Fact | ||
