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Exhibit 23.1
CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
We consent to the incorporation by reference in the following Registration Statements of Harpoon Therapeutics, Inc.:
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Registration Statement on Form S-3 (No. 333-237175) of Harpoon Therapeutics, Inc.;
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Registration Statement on Form S-8 (No. 333-229592) pertaining to the Harpoon Therapeutics, Inc. 2015 Equity Incentive Plan, 2019 Equity Incentive Plan and 2019 Employee Stock Purchase Plan;
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Registration Statement on Form S-8 (No. 333-237173) pertaining to the Harpoon Therapeutics, Inc. 2019 Equity Incentive Plan and 2019 Employee Stock Purchase Plan; and
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Registration Statement on Form S-8 (No. 333-254098) pertaining to the Harpoon Therapeutics, Inc. 2019 Equity Incentive Plan and 2019 Employee Stock Purchase Plan;
of our report dated March 10, 2022 with respect to the financial statements of Harpoon Therapeutics, Inc., included in this Annual Report (Form 10-K) for the year ended December 31, 2021.
/s/ Ernst & Young LLP
Redwood City, California
March 10, 2022