Exhibit 23.1
Consent of Independent Registered Public Accounting Firm
We consent to the reference to our firm under the caption “Experts” and to the use of our report dated , 2017 in the Registration Statement on Form F-1 and related Prospectus of Nightstar Therapeutics Limited dated August 31, 2017.
Ernst & Young LLP
Cambridge, England
, 2017
The foregoing consent is in the form that will be signed upon the completion of the corporate reorganization described in Note 1 to the consolidated financial statements.
/s/ Ernst & Young LLP
Cambridge, England
August 31, 2017
