PART I
EXPLANATORY NOTE
The Registrant is filing this Registration Statement on Form S-8 for the purpose of registering an additional 10,644,770 ordinary shares represented by American Depositary Shares (“ADSs”) under the Autolus Therapeutics plc 2018 Equity Incentive Plan (the “Plan”), pursuant to the provisions of the Plan, which provides for an annual automatic increase in the number of ordinary shares represented by ADSs reserved for issuance under the Plan. Such ADSs represent the increase that occurred on October 1, 2024, and are being registered in addition to the ADSs for which registration statements on Form S-8 (File No. 333-226457), Form S-8 (File No. 333-273776) and Form S-8 (File No. 333-275301) were filed with the Commission on July 31, 2018, August 7, 2023, and November 3, 2023, respectively (the “Prior Registration Statements”). Accordingly, the contents of the Prior Registration Statements are incorporated by reference into this Registration Statement pursuant to General Instruction E of Form S-8.
In accordance with the instructional note to Part I of Form S-8, the information specified by Part I of the Form S-8 has been omitted from this Registration Statement.
PART II
INFORMATION REQUIRED IN THE REGISTRATION STATEMENT
Item 3. Incorporation of Documents By Reference.
The following documents filed with the U.S. Securities and Exchange Commission (the “Commission”) by Autolus Therapeutics plc (the “Registrant”) are hereby incorporated by reference into this Registration Statement:
(a) the Registrant’s Annual Report on Form 10-K for the fiscal year ended December 31, 2023, filed with the Commission on March 21, 2024;
(b) the Registrant’s Quarterly Reports on Form 10-Q for the quarters ended March 31, 2024, June 30, 2024 and September 30, 2024, filed with the Commission on May 17, 2024, August 8, 2024 and November 12, 2024, respectively;
(c) the Registrant’s Reports on Form 8-K furnished to the SEC on January 10, 2024 (except for the information furnished under Item 7.01 and exhibit 99.1 thereto), February 8, 2024 (except for the information furnished under Item 7.01 and exhibit 99.1 thereto), February 8, 2024 (except for the information furnished under Item 7.01 and exhibit 99.1 thereto), March 14, 2024 (except for the information furnished under Items 2.02 and 7.01 and exhibits 99.1 and 99.2 thereto), March 21, 2024, April 1, 2024 (except for the information furnished under Item 7.01 and exhibit 99.1 thereto), June 5, 2024 (except for the information furnished under exhibits 99.1, 99.2 and 99.3 thereto), June 28, 2024, September 13, 2024, September 19, 2024 (except for the information furnished under exhibit 99.1 thereto) including the exhibits thereto, and November 12, 2024 (except for the information furnished under Item 7.01 and exhibits 99.1 and 99.2 thereto); and
(d) the descriptions of the Registrant’s American Depositary Shares and Ordinary Shares contained in the Registrant’s Registration Statement on Form 8-A filed on June 19, 2018 (File No. 001-38547) under the Securities Exchange Act of 1934, as amended (the “Exchange Act”), as updated by the description of the Registrant’s securities registered pursuant to Section 12 of the Exchange Act contained in the Registrant’s Annual Report on Form 10-K for the fiscal year ended December 31, 2023, including any amendment or report filed for the purpose of updating such description.
All documents subsequently filed by the Registrant pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Exchange Act subsequent to the date of this Registration Statement and prior to the filing of a post-effective amendment to this Registration Statement which indicates that all securities offered hereby have been sold or which deregisters all such securities then remaining unsold, shall be deemed to be incorporated by reference herein and to be a part hereof from the date of filing of such documents.