September 25, 2020
U.S. Securities and Exchange Commission
Office of Life Sciences
Division of Corporation Finance
100 F Street, N.E.
Mail Stop 4546
Washington, D.C. 20549
Attn: | Mr. Alan Campbell |
Ms. Christine Westbrook
Mr. David Burton
Ms. Mary Mast
Re: | Orphazyme A/S |
Registration Statement on Form F-1, as amended
File No. 333-248607
Ladies and Gentlemen:
In connection with the above-referenced Registration Statement, and pursuant to Rule 461 under the Securities Act of 1933, as amended (the “Act”), we hereby join in the request of Orphazyme A/S that the effective date of the Registration Statement be accelerated so that it will be declared effective at 4:00 p.m., Eastern Daylight Time, on September 28, 2020, or as soon thereafter as practicable. We hereby formally withdraw our original request for acceleration, dated September 22, 2020, pursuant to which acceleration had previously been requested at 4:00 p.m., Eastern Daylight Time, on September 24, 2020, or as soon thereafter as practicable.
Pursuant to Rule 460 under the Act, please be advised that we expect to deliver approximately 974 copies of the Preliminary Prospectus dated September 25, 2020 (the “Preliminary Prospectus”) through the date hereof, to underwriters, dealers, institutions and others.
In connection with the Preliminary Prospectus distribution for the above-referenced issue, the prospective underwriters have confirmed that they are complying with the 48-hour requirement in Rule 15c2-8(b) under the Securities Exchange Act of 1934, as amended.
Very truly yours,
BOFA SECURITIES, INC.
COWEN AND COMPANY, LLC
GUGGENHEIM SECURITIES, LLC
As Representatives of the several underwriters
[Signature Pages Follow]
BOFA SECURITIES, INC.
By: /s/ Michele A.H. Allong
Name: Michele A.H. Allong
Title: Authorized Signatory
COWEN AND COMPANY, LLC
By: /s/ Tanya Joseph
Name: Tanya Joseph
Title: Managing Director
GUGGENHEIM SECURITIES, LLC
By: /s/ Stuart Duty
Name: Stuart Duty
Title: Senior Managing Director
As representatives of the several underwriters.
cc: Ilir Mujalovic, Partner, Shearman & Sterling LLP
[Signature Page to Acceleration Request Letter]