November 18, 2019
United States Securities and Exchange Commission
Division of Corporation Finance
Mail Stop 4561
100 F Street, N.E.
Washington, D.C. 20549
Attention: Ms. Christine Westbrook
| Re: | Karuna Therapeutics, Inc. |
Registration Statement on FormS-1 (FileNo. 333-234756)
Request for Acceleration
Ladies and Gentlemen:
Pursuant to Rule 460 of the General Rules and Regulations under the Securities Act of 1933, as amended, please be advised that we will take reasonable steps to secure adequate distribution of the preliminary prospectus to underwriters, dealers, institutions and others, prior to the requested effective time of the Registration Statement.
We wish to advise you that the participating underwriters have informed us that they have complied and will continue to comply with the requirements of Rule15c2-8 under the Securities Exchange Act of 1934, as amended.
We hereby join in the request of the registrant that the effectiveness of the above-captioned Registration Statement, as amended, be accelerated to 4:00 p.m. Eastern Time, on Wednesday, November 20, 2019or as soon thereafter as practicable.
[Signature page follows]
| Very truly yours, | ||
| GOLDMAN SACHS & CO. LLC | ||
| CITIGROUP GLOBAL MARKETS INC. | ||
| As representatives of the Underwriters | ||
| GOLDMAN SACHS & CO. LLC | ||
| By: | /s/ Kristen Grippi | |
| Name: | Kristen Grippi | |
| Title: | Managing Director | |
| CITIGROUP GLOBAL MARKETS INC. | ||
| By: | /s/ Jennifer Sheng | |
| Name: | Jennifer Sheng | |
| Title: | Managing Director | |
[Signature Page to Karuna Therapeutics, Inc. Acceleration Request]
