Affinity Asset Advisors 13F-HR Quarterly holdings report by institutional manager

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL

OMB Number:		3235-0006
Expires:	Oct 31, 2018
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COLUMN 1	COLUMN 2	COLUMN 3	COLUMN 4	COLUMN 5			COLUMN 6	COLUMN 7	COLUMN 8
			VALUE	SHRS OR	SH/	PUT/	INVESTMENT	OTHER	VOTING AUTHORITY
NAME OF ISSUER	TITLE OF CLASS	CUSIP	(x$1000)	PRN AMT	PRN	CALL	DISCRETION	MANAGER	SOLE	SHARED	NONE
ADC THERAPEUTICS SA	SHS	H0036K147	1,500,191	474,744	SH		SOLE		474,744	0	0
AEROVATE THERAPEUTICS INC	COM	008064107	332,000	200,000	SH		SOLE		200,000	0	0
ALKERMES PLC	SHS	G01767105	15,665,000	650,000	SH		SOLE		650,000	0	0
ALNYLAM PHARMACEUTICALS INC	NOTE 1.000% 9/1	02043QAB3	16,200,000	15,000,000	PRN		SOLE		15,000,000	0	0
ALX ONCOLOGY HLDGS INC	COM	00166B105	603,000	100,000	SH	Call	SOLE		100,000	0	0
APOGEE THERAPEUTICS INC	COM	03770N101	32,907,736	836,283	SH		SOLE		836,283	0	0
ARCA BIOPHARMA INC	COM	00211Y506	277,614	72,484	SH		SOLE		72,484	0	0
ARCELLX INC	COMMON STOCK	03940C100	25,387,400	460,000	SH		SOLE		460,000	0	0
ARROWHEAD PHARMACEUTICALS IN	COM	04280A100	1,299,500	50,000	SH		SOLE		50,000	0	0
ARYA SCIENCES ACQU CORP IV	CL A	G31659108	1,529,910	133,500	SH		SOLE		133,500	0	0
ASTRIA THERAPEUTICS INC	COM	04635X102	8,878,015	975,606	SH		SOLE		975,606	0	0
AUTOLUS THERAPEUTICS PLC	SPON ADS	05280R100	14,964,000	4,300,000	SH		SOLE		4,300,000	0	0
AVALO THERAPEUTICS INC	COM NEW	05338F306	561,150	45,000	SH		SOLE		45,000	0	0
AXSOME THERAPEUTICS INC	COM	05464T104	6,440,000	80,000	SH		SOLE		80,000	0	0
BEIGENE LTD	SPONSORED ADR	07725L102	15,693,700	110,000	SH		SOLE		110,000	0	0
BLACK DIAMOND THERAPEUTICS I	COM	09203E105	3,029,000	650,000	SH		SOLE		650,000	0	0
BRIDGEBIO PHARMA INC	NOTE 2.500% 3/1	10806XAB8	17,256,850	17,000,000	PRN		SOLE		17,000,000	0	0
BRIDGEBIO PHARMA INC	COM	10806X102	2,533,000	100,000	SH		SOLE		100,000	0	0
CELLDEX THERAPEUTICS INC NEW	COM NEW	15117B202	17,594,554	475,400	SH		SOLE		475,400	0	0
CENTESSA PHARMACEUTICALS PLC	SPONSORED ADS	152309100	10,255,389	1,135,702	SH		SOLE		1,135,702	0	0
CEREVEL THERAPEUTICS HLDNG I	COM	15678U128	20,445,000	500,000	SH		SOLE		500,000	0	0
CEREVEL THERAPEUTICS HLDNG I	COM	15678U128	10,222,500	250,000	SH	Call	SOLE		250,000	0	0
COHERUS BIOSCIENCES INC	NOTE 1.500% 4/1	19249HAB9	8,636,281	11,750,000	PRN		SOLE		11,750,000	0	0
COMPASS PATHWAYS PLC	SPONSORED ADS	20451W101	3,023,092	500,512	SH		SOLE		500,512	0	0
CONTEXT THERAPEUTICS INC	COM	21077P108	3,246,376	1,619,140	SH		SOLE		1,619,140	0	0
CRINETICS PHARMACEUTICALS IN	COM	22663K107	23,066,850	515,000	SH		SOLE		515,000	0	0
CULLINAN THERAPEUTICS INC	COM	230031106	4,600,968	263,817	SH		SOLE		263,817	0	0
DYNE THERAPEUTICS INC	COM	26818M108	3,529,000	100,000	SH		SOLE		100,000	0	0
ELEVATION ONCOLOGY INC	COM	28623U101	3,965,828	1,468,825	SH		SOLE		1,468,825	0	0
ELIEM THERAPEUTICS INC	COM	28658R106	11,878,400	1,670,661	SH		SOLE		1,670,661	0	0
ERASCA INC	COM	29479A108	5,898,657	2,499,431	SH		SOLE		2,499,431	0	0
ESTABLISHMENT LABS HLDGS INC	COM	G31249108	10,151,614	223,407	SH		SOLE		223,407	0	0
FULCRUM THERAPEUTICS INC	COM	359616109	1,550,000	250,000	SH	Call	SOLE		250,000	0	0
GENELUX CORPORATION	COM	36870H103	195,000	100,000	SH		SOLE		100,000	0	0
GERON CORP	COM	374163103	6,360,000	1,500,000	SH		SOLE		1,500,000	0	0
HELIX ACQUISITION CORP II	CL A ORD SHS	G4444H101	2,555,000	250,000	SH		SOLE		250,000	0	0
HILLEVAX INC	COM	43157M102	3,844,321	265,859	SH		SOLE		265,859	0	0
IMMATICS N.V	SHS	N44445109	3,486,000	300,000	SH		SOLE		300,000	0	0
IMMATICS N.V	*W EXP 07/01/202	N44445117	484,858	187,204	SH		SOLE		187,204	0	0
IMMUNOVANT INC	COM	45258J102	9,136,723	346,088	SH		SOLE		346,088	0	0
IMMUNOVANT INC	COM	45258J102	1,433,520	54,300	SH	Call	SOLE		54,300	0	0
INARI MED INC	COM	45332Y109	9,630,000	200,000	SH		SOLE		200,000	0	0
INOZYME PHARMA INC	COM	45790W108	12,738,884	2,856,252	SH		SOLE		2,856,252	0	0
INSMED INC	COM PAR $.01	457669307	8,375,000	125,000	SH		SOLE		125,000	0	0
INSMED INC	COM PAR $.01	457669307	582,900	8,700	SH	Put	SOLE		8,700	0	0
IOVANCE BIOTHERAPEUTICS INC	COM	462260100	1,203,000	150,000	SH	Put	SOLE		150,000	0	0
IOVANCE BIOTHERAPEUTICS INC	COM	462260100	802	100	SH		SOLE		100	0	0
KARYOPHARM THERAPEUTICS INC	NOTE 3.000%10/1	48576UAA4	6,296,453	9,750,000	PRN		SOLE		9,750,000	0	0
KEZAR LIFE SCIENCES INC	COM	49372L100	1,057,067	1,761,778	SH		SOLE		1,761,778	0	0
KURA ONCOLOGY INC	COM	50127T109	13,383,500	650,000	SH		SOLE		650,000	0	0
KYVERNA THERAPEUTICS INC	COM	501976104	1,500,000	200,000	SH		SOLE		200,000	0	0
MADRIGAL PHARMACEUTICALS INC	COM	558868105	30,817,600	110,000	SH		SOLE		110,000	0	0
MERSANA THERAPEUTICS INC	COM	59045L106	1,541,670	767,000	SH		SOLE		767,000	0	0
MERUS N V	COM	N5749R100	7,396,250	125,000	SH		SOLE		125,000	0	0
MINERALYS THERAPEUTICS INC	COM	603170101	3,837,120	327,959	SH		SOLE		327,959	0	0
MIRUM PHARMACEUTICALS INC	COM	604749101	5,299,450	155,000	SH		SOLE		155,000	0	0
MORPHIC HLDG INC	COM	61775R105	8,537,022	250,573	SH		SOLE		250,573	0	0
NEUROBO PHARMACEUTICALS IN	COM	64132R404	431,834	89,222	SH		SOLE		89,222	0	0
NEWAMSTERDAM PHARMA COMPANY	ORDINARY SHARES	N62509109	8,128,808	423,155	SH		SOLE		423,155	0	0
NEWAMSTERDAM PHARMA COMPANY	*W EXP 99/99/999	N62509117	1,916,587	202,599	SH		SOLE		202,599	0	0
NEXTCURE INC	COM	65343E108	2,683,848	1,687,955	SH		SOLE		1,687,955	0	0
NKARTA INC	COM	65487U108	1,182,000	200,000	SH		SOLE		200,000	0	0
NURIX THERAPEUTICS INC	COM	67080M103	19,033,440	912,000	SH		SOLE		912,000	0	0
NUVALENT INC	COM	670703107	15,172,000	200,000	SH		SOLE		200,000	0	0
OLEMA PHARMACEUTICALS INC	COM	68062P106	2,975,500	275,000	SH		SOLE		275,000	0	0
OMEROS CORP	NOTE 5.250% 2/1	682143AG7	8,083,023	11,450,000	PRN		SOLE		11,450,000	0	0
PASSAGE BIO INC	COM	702712100	209,880	264,266	SH		SOLE		264,266	0	0
PERCEPTIVE CAP SOLUTIONS COR	CL A ORD SHS	G70077105	3,521,000	350,000	SH		SOLE		350,000	0	0
PERSPECTIVE THERAPEUTICS INC	COM NEW	46489V302	5,483,500	550,000	SH		SOLE		550,000	0	0
PROMIS NEUROSCIENCES INC	COM NEW	74346M406	398,937	265,958	SH		SOLE		265,958	0	0
PUMA BIOTECHNOLOGY INC	COM	74587V107	815,000	250,000	SH		SOLE		250,000	0	0
Q32 BIO INC	COM	746964105	498,597	27,777	SH		SOLE		27,777	0	0
RAPT THERAPEUTICS INC	COM	75382E109	1,662,250	545,000	SH	Put	SOLE		545,000	0	0
RAPT THERAPEUTICS INC	COM	75382E109	228,750	75,000	SH		SOLE		75,000	0	0
REZOLUTE INC	COM NEW	76200L309	7,955,000	1,850,000	SH		SOLE		1,850,000	0	0
ROCKET PHARMACEUTICALS INC	*W EXP 09/02/202	77313F114	4,523	75,000	SH		SOLE		75,000	0	0
ROIVANT SCIENCES LTD	SHS	G76279101	3,716,275	351,587	SH		SOLE		351,587	0	0
SANA BIOTECHNOLOGY INC	COM	799566104	2,844,660	521,000	SH	Put	SOLE		521,000	0	0
SAVARA INC	COM	805111101	6,233,806	1,546,850	SH		SOLE		1,546,850	0	0
SPDR S&P 500 ETF TR	TR UNIT	78462F103	190,477,000	350,000	SH	Put	SOLE		350,000	0	0
SPDR SER TR	S&P BIOTECH	78464A870	3,481,261	37,550	SH		SOLE		37,550	0	0
SPRINGWORKS THERAPEUTICS INC	COM	85205L107	2,636,862	69,999	SH		SOLE		69,999	0	0
SPYRE THERAPEUTICS INC	COM NEW	00773J202	12,070,504	513,420	SH		SOLE		513,420	0	0
TANGO THERAPEUTICS INC	COM	87583X109	1,289,351	150,274	SH		SOLE		150,274	0	0
TECTONIC THERAPEUTIC INC	COM	878972108	960,712	58,331	SH		SOLE		58,331	0	0
TEVA PHARMACEUTICAL INDS LTD	SPONSORED ADS	881624209	23,562,500	1,450,000	SH		SOLE		1,450,000	0	0
TEVA PHARMACEUTICAL INDS LTD	SPONSORED ADS	881624209	18,687,500	1,150,000	SH	Call	SOLE		1,150,000	0	0
TWIST BIOSCIENCE CORP	COM	90184D100	2,217,600	45,000	SH	Call	SOLE		45,000	0	0
VAXCYTE INC	COM	92243G108	4,530,600	60,000	SH		SOLE		60,000	0	0
VAXCYTE INC	COM	92243G108	1,132,650	15,000	SH	Call	SOLE		15,000	0	0
VERA THERAPEUTICS INC	CL A	92337R101	13,567,500	375,000	SH		SOLE		375,000	0	0
VERONA PHARMA PLC	SPONSORED ADS	925050106	10,122,000	700,000	SH		SOLE		700,000	0	0
VIR BIOTECHNOLOGY INC	COM	92764N102	1,780,000	200,000	SH		SOLE		200,000	0	0
VIRIDIAN THERAPEUTICS INC	COM	92790C104	1,951,500	150,000	SH		SOLE		150,000	0	0
WAVE LIFE SCIENCES LTD	SHS	Y95308105	1,871,250	375,000	SH		SOLE		375,000	0	0
XENON PHARMACEUTICALS INC	COM	98420N105	38,764,911	994,227	SH		SOLE		994,227	0	0
ZURA BIO LTD	CLASS A ORD SHS	G9TY5A101	781,673	223,335	SH		SOLE		223,335	0	0
ZYMEWORKS INC	COM	98985Y108	1,626,491	191,127	SH		SOLE		191,127	0	0