EXHIBIT A
Agreement of Joint Filing
The undersigned hereby agree that a single Form 3 (or any amendment thereto) relating to the common stock of the Issuer shall be filed on behalf of each of the undersigned and that this Agreement shall be filed as an exhibit to such Form 3.
Date: April 22, 2019
| Global Life Bioventure V, S.à r.l. |
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| By: | | /s/ Richard Lim |
| Name: | | Richard Lim |
| Title: | | Class A Manager |
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| By: | | /s/ Matthijs Bogers |
| Name: | | Matthijs Bogers |
| Title: | | Class B Manager |
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| Omega Fund V, L.P. |
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| By: | | Omega Fund V GP, L.P. |
| Its: | | General Partner |
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| By: | | Omega Fund V GP Manager, Ltd. |
| Its: | | General Partner |
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| By: | | /s/ Richard Lim |
| Name: | | Richard Lim |
| Title: | | Director |
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| Omega Fund V GP, L.P. |
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| By: | | Omega Fund V GP Manager, Ltd. |
| Its: | | General Partner |
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| By: | | /s/ Richard Lim |
| Name: | | Richard Lim |
| Title: | | Director |
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| Omega Fund V GP Manager, Ltd. |
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| By: | | /s/ Richard Lim |
| Name: | | Richard Lim |
| Title: | | Director |
| Richard Lim |
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| By: | | /s/ Richard Lim |
| Name: | | Richard Lim |
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| Otello Stampacchia |
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| By: | | /s/ Otello Stampacchia |
| Name: | | Otello Stampacchia |
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| Claudio Nessi |
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| By: | | /s/ Claudio Nessi |
| Name: | | Claudio Nessi |
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| Anne-Mari Paster |
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| By: | | /s/ Anne-Mari Paster |
| Name: | | Anne-Mari Paster |