Ikarian Capital 13F-HR Quarterly holdings report by institutional manager

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL

OMB Number:		3235-0006
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COLUMN 1	COLUMN 2	COLUMN 3	COLUMN 4	COLUMN 5			COLUMN 6	COLUMN 7	COLUMN 8
			VALUE	SHRS OR	SH/	PUT/	INVESTMENT	OTHER	VOTING AUTHORITY
NAME OF ISSUER	TITLE OF CLASS	CUSIP	(x$1000)	PRN AMT	PRN	CALL	DISCRETION	MANAGER	SOLE	SHARED	NONE
ACADIA PHARMACEUTICALS INC	COM	004225108	5,989	140,000	SH	Put	SOLE		140,000	0	0
ADURO BIOTECH INC	COM	00739L101	2,169	1,838,528	SH		SOLE		1,838,528	0	0
ADVERUM BIOTECHNOLOGIES INC	COM	00773U108	4,503	390,900	SH	Call	SOLE		390,900	0	0
AETERNA ZENTARIS INC	COM	007975402	107	117,443	SH		SOLE		117,443	0	0
AGIOS PHARMACEUTICALS INC	COM	00847X104	2,388	50,000	SH	Call	SOLE		50,000	0	0
AIMMUNE THERAPEUTICS INC	COM	00900T107	1,339	40,000	SH		SOLE		40,000	0	0
ALLAKOS INC	COM	01671P100	15,143	158,800	SH	Call	SOLE		158,800	0	0
ALPINE IMMUNE SCIENCES INC	COM	02083G100	18	4,739	SH		SOLE		4,739	0	0
AMARIN CORP PLC	SPONS ADR NEW	023111206	4,663	217,500	SH	Call	SOLE		217,500	0	0
ANAPTYSBIO INC	COM	032724106	2,324	143,000	SH		SOLE		143,000	0	0
ANAPTYSBIO INC	COM	032724106	3,141	193,300	SH	Put	SOLE		193,300	0	0
APELLIS PHARMACEUTICALS INC	COM	03753U106	8,785	286,900	SH	Put	SOLE		286,900	0	0
APELLIS PHARMACEUTICALS INC	COM	03753U106	7,358	240,300	SH	Call	SOLE		240,300	0	0
APELLIS PHARMACEUTICALS INC	COM	03753U106	2	53	SH		SOLE		53	0	0
APPLIED GENETIC TECHNOL CORP	COM	03820J100	908	200,884	SH		SOLE		200,884	0	0
APTOSE BIOSCIENCES INC	COM NEW	03835T200	5,725	1,009,735	SH		SOLE		1,009,735	0	0
ARDELYX INC	COM	039697107	4,844	645,436	SH		SOLE		645,436	0	0
ARQULE INC	COM	04269E107	9,934	497,700	SH	Call	SOLE		497,700	0	0
ARQULE INC	COM	04269E107	2,973	148,930	SH		SOLE		148,930	0	0
ARQULE INC	COM	04269E107	6,715	336,400	SH	Put	SOLE		336,400	0	0
ARROWHEAD PHARMACEUTICALS IN	COM	04280A100	6,343	100,000	SH	Put	SOLE		100,000	0	0
ARROWHEAD PHARMACEUTICALS IN	COM	04280A100	6,343	100,000	SH	Call	SOLE		100,000	0	0
ARVINAS INC	COM	04335A105	127	3,100	SH	Call	SOLE		3,100	0	0
ARVINAS INC	COM	04335A105	127	3,100	SH	Put	SOLE		3,100	0	0
ASCENDIS PHARMA A S	SPONSORED ADR	04351P101	9,655	69,400	SH	Call	SOLE		69,400	0	0
ASSEMBLY BIOSCIENCES INC	COM	045396108	3,222	157,468	SH		SOLE		157,468	0	0
ASSEMBLY BIOSCIENCES INC	COM	045396108	3,069	150,000	SH	Put	SOLE		150,000	0	0
AURINIA PHARMACEUTICALS INC	COM	05156V102	9,747	481,104	SH		SOLE		481,104	0	0
AXOVANT GENE THERAPIES LTD	COM	G0750W203	967	188,884	SH		SOLE		188,884	0	0
AXSOME THERAPEUTICS INC	COM	05464T104	2,884	27,900	SH	Put	SOLE		27,900	0	0
BEIGENE LTD	SPONSORED ADR	07725L102	12,764	77,000	SH	Put	SOLE		77,000	0	0
BELLUS HEALTH INC NEW	COM NEW	07987C204	625	63,721	SH		SOLE		63,721	0	0
BIOHAVEN PHARMACTL HLDG CO L	COM	G11196105	35	642	SH		SOLE		642	0	0
BIOHAVEN PHARMACTL HLDG CO L	COM	G11196105	10,888	200,000	SH	Call	SOLE		200,000	0	0
BIOXCEL THERAPEUTICS INC	COM	09075P105	2,314	158,373	SH		SOLE		158,373	0	0
CARA THERAPEUTICS INC	COM	140755109	285	17,700	SH	Call	SOLE		17,700	0	0
CARA THERAPEUTICS INC	COM	140755109	68	4,200	SH	Put	SOLE		4,200	0	0
CEL SCI CORP	COM PAR NEW	150837607	2,747	300,200	SH	Put	SOLE		300,200	0	0
CERECOR INC	COM	15671L109	2,802	519,800	SH		SOLE		519,800	0	0
CHEMOCENTRYX INC	COM	16383L106	1,836	46,423	SH		SOLE		46,423	0	0
CHIASMA INC	COM	16706W102	5,472	1,103,297	SH		SOLE		1,103,297	0	0
CHIMERIX INC	COM	16934W106	351	172,920	SH		SOLE		172,920	0	0
CLOVIS ONCOLOGY INC	COM	189464100	5,355	513,700	SH	Call	SOLE		513,700	0	0
COHERUS BIOSCIENCES INC	COM	19249H103	1,514	84,100	SH	Call	SOLE		84,100	0	0
CRISPR THERAPEUTICS AG	NAMEN AKT	H17182108	7,534	123,700	SH	Put	SOLE		123,700	0	0
DBV TECHNOLOGIES S A	SPONSORED ADR	23306J101	798	74,538	SH		SOLE		74,538	0	0
DECIPHERA PHARMACEUTICALS IN	COM	24344T101	6,224	100,000	SH	Call	SOLE		100,000	0	0
DICERNA PHARMACEUTICALS INC	COM	253031108	341	15,500	SH	Call	SOLE		15,500	0	0
EIDOS THERAPEUTICS INC	COM	28249H104	5,739	100,000	SH	Call	SOLE		100,000	0	0
GILEAD SCIENCES INC	COM	375558103	32,490	500,000	SH	Call	SOLE		500,000	0	0
GLOBAL BLOOD THERAPEUTICS IN	COM	37890U108	7,949	100,000	SH	Call	SOLE		100,000	0	0
GOSSAMER BIO INC	COM	38341P102	12,052	771,100	SH	Put	SOLE		771,100	0	0
GW PHARMACEUTICALS PLC	ADS	36197T103	10,456	100,000	SH	Call	SOLE		100,000	0	0
IMMUNOMEDICS INC	COM	452907108	9,484	448,200	SH	Call	SOLE		448,200	0	0
IMMUNOVANT INC	COM	45258J102	8,000	504,117	SH		SOLE		504,117	0	0
INCYTE CORP	COM	45337C102	6,986	80,000	SH	Call	SOLE		80,000	0	0
INFLARX NV	COM	N44821101	1,422	359,128	SH		SOLE		359,128	0	0
INSMED INC	COM PAR $.01	457669307	1,461	61,200	SH	Call	SOLE		61,200	0	0
INTERCEPT PHARMACEUTICALS IN	COM	45845P108	8,042	64,900	SH	Call	SOLE		64,900	0	0
INTERCEPT PHARMACEUTICALS IN	COM	45845P108	93,547	754,900	SH	Put	SOLE		754,900	0	0
INTRA CELLULAR THERAPIES INC	COM	46116X101	9,164	267,100	SH	Call	SOLE		267,100	0	0
INTRA CELLULAR THERAPIES INC	COM	46116X101	31,706	924,100	SH	Put	SOLE		924,100	0	0
ISHARES TR	NASDAQ BIOTECH	464287556	30,128	250,000	SH	Put	SOLE		250,000	0	0
KALA PHARMACEUTICALS INC	COM	483119103	3,776	1,023,431	SH		SOLE		1,023,431	0	0
KALA PHARMACEUTICALS INC	COM	483119103	1,459	395,500	SH	Call	SOLE		395,500	0	0
KALVISTA PHARMACEUTICALS INC	COM	483497103	3,783	212,420	SH		SOLE		212,420	0	0
KARYOPHARM THERAPEUTICS INC	COM	48576U106	3,836	200,100	SH	Put	SOLE		200,100	0	0
MACROGENICS INC	COM	556099109	109	10,030	SH		SOLE		10,030	0	0
MACROGENICS INC	COM	556099109	1,632	150,000	SH	Call	SOLE		150,000	0	0
MADRIGAL PHARMACEUTICALS INC	COM	558868105	9,111	100,000	SH	Put	SOLE		100,000	0	0
MADRIGAL PHARMACEUTICALS INC	COM	558868105	4,079	44,770	SH		SOLE		44,770	0	0
MAGENTA THERAPEUTICS INC	COM	55910K108	131	8,674	SH		SOLE		8,674	0	0
MALLINCKRODT PUB LTD CO	SHS	G5785G107	1,787	512,000	SH		SOLE		512,000	0	0
MINERVA NEUROSCIENCES INC	COM	603380106	530	74,500	SH	Call	SOLE		74,500	0	0
MINERVA NEUROSCIENCES INC	COM	603380106	711	100,000	SH		SOLE		100,000	0	0
MIRATI THERAPEUTICS INC	COM	60468T105	6,301	48,900	SH	Put	SOLE		48,900	0	0
MIRATI THERAPEUTICS INC	COM	60468T105	12,886	100,000	SH	Call	SOLE		100,000	0	0
MOLECULAR TEMPLATES INC	COM	608550109	572	40,907	SH		SOLE		40,907	0	0
MUSTANG BIO INC	COM	62818Q104	1,319	323,235	SH		SOLE		323,235	0	0
MYOKARDIA INC	COM	62857M105	4,300	59,000	SH	Put	SOLE		59,000	0	0
NEUROCRINE BIOSCIENCES INC	COM	64125C109	774	7,200	SH	Call	SOLE		7,200	0	0
NOVAVAX INC	COM NEW	670002401	100	25,049	SH		SOLE		25,049	0	0
OBSEVA SA	COM	H5861P103	315	82,573	SH		SOLE		82,573	0	0
OCULAR THERAPEUTIX INC	COM	67576A100	593	150,000	SH	Call	SOLE		150,000	0	0
OCULAR THERAPEUTIX INC	COM	67576A100	2,203	557,659	SH		SOLE		557,659	0	0
OTONOMY INC	COM	68906L105	4,088	1,067,271	SH		SOLE		1,067,271	0	0
OVID THERAPEUTICS INC	COM	690469101	1,453	350,000	SH		SOLE		350,000	0	0
PIERIS PHARMACEUTICALS INC	COM	720795103	80	22,000	SH	Call	SOLE		22,000	0	0
PRECISION BIOSCIENCES INC	COM	74019P108	1,111	80,000	SH		SOLE		80,000	0	0
PROGENICS PHARMACEUTICALS IN	COM	743187106	666	130,845	SH		SOLE		130,845	0	0
PROTAGONIST THERAPEUTICS INC	COM	74366E102	552	78,326	SH		SOLE		78,326	0	0
PROTEON THERAPEUTICS INC	COM	74371L109	138	336,373	SH		SOLE		336,373	0	0
PROTHENA CORP PLC	SHS	G72800108	472	29,832	SH		SOLE		29,832	0	0
PUMA BIOTECHNOLOGY INC	COM	74587V107	1,161	132,700	SH	Call	SOLE		132,700	0	0
PUMA BIOTECHNOLOGY INC	COM	74587V107	2,723	311,253	SH		SOLE		311,253	0	0
RIGEL PHARMACEUTICALS INC	COM NEW	766559603	749	350,000	SH		SOLE		350,000	0	0
SAGE THERAPEUTICS INC	COM	78667J108	9,601	133,000	SH		SOLE		133,000	0	0
SAREPTA THERAPEUTICS INC	COM	803607100	13,240	102,600	SH	Call	SOLE		102,600	0	0
SIERRA ONCOLOGY INC	COM	82640U107	132	386,399	SH		SOLE		386,399	0	0
SOLID BIOSCIENCES INC	COM	83422E105	1,360	305,600	SH	Call	SOLE		305,600	0	0
SPDR SERIES TRUST	S&P BIOTECH	78464A870	33,289	350,000	SH	Put	SOLE		350,000	0	0
STEALTH BIOTHERAPEUTICS CORP	SPONSORED ADS	85789A105	123	37,597	SH		SOLE		37,597	0	0
SUNESIS PHARMACEUTICALS INC	COM	867328700	38	111,445	SH		SOLE		111,445	0	0
TG THERAPEUTICS INC	COM	88322Q108	3,510	316,200	SH		SOLE		316,200	0	0
ULTRAGENYX PHARMACEUTICAL IN	COM	90400D108	2,136	50,000	SH		SOLE		50,000	0	0
VIKING THERAPEUTICS INC	COM	92686J106	1,203	150,000	SH	Call	SOLE		150,000	0	0
VIKING THERAPEUTICS INC	COM	92686J106	1,012	126,159	SH		SOLE		126,159	0	0
VIKING THERAPEUTICS INC	COM	92686J106	1,203	150,000	SH	Put	SOLE		150,000	0	0
WAVE LIFE SCIENCES LTD	SHS	Y95308105	1,077	134,400	SH	Call	SOLE		134,400	0	0
WAVE LIFE SCIENCES LTD	SHS	Y95308105	2,405	300,000	SH	Put	SOLE		300,000	0	0
X4 PHARMACEUTICALS INC	COM	98420X103	107	10,000	SH		SOLE		10,000	0	0
XENON PHARMACEUTICALS INC	COM	98420N105	3,192	243,470	SH		SOLE		243,470	0	0
ZOGENIX INC	COM NEW	98978L204	240	4,600	SH	Call	SOLE		4,600	0	0
ZOGENIX INC	COM NEW	98978L204	7,726	148,200	SH	Put	SOLE		148,200	0	0