Ikarian Capital 13F-HR Quarterly holdings report by institutional manager

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL

OMB Number:		3235-0006
Expires:	Oct 31, 2018
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COLUMN 1	COLUMN 2	COLUMN 3	COLUMN 4	COLUMN 5			COLUMN 6	COLUMN 7	COLUMN 8
			VALUE	SHRS OR	SH/	PUT/	INVESTMENT	OTHER	VOTING AUTHORITY
NAME OF ISSUER	TITLE OF CLASS	CUSIP	(x$1000)	PRN AMT	PRN	CALL	DISCRETION	MANAGER	SOLE	SHARED	NONE
ACADIA PHARMACEUTICALS INC	COM	004225108	2,230	46,008	SH		SOLE		46,008	0	0
ACADIA PHARMACEUTICALS INC	COM	004225108	9,694	200,000	SH	Put	SOLE		200,000	0	0
ACCELERON PHARMA INC	COM	00434H108	17,882	187,700	SH	Call	SOLE		187,700	0	0
ACCELERON PHARMA INC	COM	00434H108	3,287	34,500	SH	Put	SOLE		34,500	0	0
ACHIEVE LIFE SCIENCE INC	COM NEW	004468203	1,452	3,658,537	SH		SOLE		3,658,537	0	0
ADMA BIOLOGICS INC	COM	000899104	1,109	378,574	SH		SOLE		378,574	0	0
ADURO BIOTECH INC	COM	00739L101	7,785	3,369,976	SH		SOLE		3,369,976	0	0
ADVERUM BIOTECHNOLOGIES INC	COM	00773U108	7,490	358,700	SH	Call	SOLE		358,700	0	0
ADVERUM BIOTECHNOLOGIES INC	COM	00773U108	1,979	94,800	SH	Put	SOLE		94,800	0	0
ADVERUM BIOTECHNOLOGIES INC	COM	00773U108	477	22,840	SH		SOLE		22,840	0	0
AETERNA ZENTARIS INC	COM	007975402	94	117,443	SH		SOLE		117,443	0	0
ALBIREO PHARMA INC	COM	01345P106	2,662	100,500	SH	Call	SOLE		100,500	0	0
ALLAKOS INC	COM	01671P100	3,057	42,536	SH		SOLE		42,536	0	0
ALPINE IMMUNE SCIENCES INC	COM	02083G100	46	4,739	SH		SOLE		4,739	0	0
ALTIMMUNE INC	COM NEW	02155H200	1,767	165,000	SH		SOLE		165,000	0	0
AMERICAN CAMPUS CMNTYS INC	COM	024835100	19,228	550,000	SH	Put	SOLE		550,000	0	0
ANAPTYSBIO INC	COM	032724106	102	4,581	SH		SOLE		4,581	0	0
APELLIS PHARMACEUTICALS INC	COM	03753U106	69	2,126	SH		SOLE		2,126	0	0
APPLIED GENETIC TECHNOLOGIES	COM	03820J100	3,024	545,884	SH		SOLE		545,884	0	0
APTINYX INC	COM	03836N103	2,464	591,000	SH		SOLE		591,000	0	0
ARDELYX INC	COM	039697107	9,637	1,392,565	SH		SOLE		1,392,565	0	0
ARENA PHARMACEUTICALS INC	COM NEW	040047607	315	5,000	SH		SOLE		5,000	0	0
ARGENX SE	SPONSORED ADR	04016X101	394	1,750	SH		SOLE		1,750	0	0
ARGENX SE	SPONSORED ADR	04016X101	28,334	125,800	SH	Put	SOLE		125,800	0	0
ARVINAS INC	COM	04335A105	5,165	154,000	SH	Put	SOLE		154,000	0	0
ARVINAS INC	COM	04335A105	3,559	106,100	SH	Call	SOLE		106,100	0	0
ASCENDIS PHARMA A S	SPONSORED ADR	04351P101	21,446	145,000	SH	Call	SOLE		145,000	0	0
ASSEMBLY BIOSCIENCES INC	COM	045396108	3,672	157,468	SH		SOLE		157,468	0	0
AURINIA PHARMACEUTICALS INC	COM	05156V102	5,326	327,771	SH		SOLE		327,771	0	0
AVADEL PHARMACEUTICALS PLC	SPONSORED ADR	05337M104	3,936	487,143	SH		SOLE		487,143	0	0
AXOVANT GENE THERAPIES	COM	G0750W203	533	188,884	SH		SOLE		188,884	0	0
AXSOME THERAPEUTICS INC	COM	05464T104	1,506	18,300	SH	Call	SOLE		18,300	0	0
BAUDAX BIO INC	COM	07160F107	415	100,000	SH		SOLE		100,000	0	0
BIOGEN INC	COM	09062X103	213	795	SH		SOLE		795	0	0
BIOHAVEN PHARMACTL HLDG CO L	COM	G11196105	3,656	50,000	SH	Call	SOLE		50,000	0	0
BIOMARIN PHARMACEUTICAL INC	COM	09061G101	4,650	37,700	SH	Call	SOLE		37,700	0	0
BIOXCEL THERAPEUTICS INC	COM	09075P105	14,250	268,818	SH		SOLE		268,818	0	0
BIOXCEL THERAPEUTICS INC	COM	09075P105	7,888	148,800	SH	Call	SOLE		148,800	0	0
BLACK DIAMOND THERAPEUTICS I	COM	09203E105	7,485	177,544	SH		SOLE		177,544	0	0
BLUEBIRD BIO INC	COM	09609G100	2,136	35,000	SH	Call	SOLE		35,000	0	0
BLUEBIRD BIO INC	COM	09609G100	6,402	104,874	SH		SOLE		104,874	0	0
BLUEPRINT MEDICINES CORP	COM	09627Y109	15,730	201,662	SH		SOLE		201,662	0	0
BLUEPRINT MEDICINES CORP	COM	09627Y109	10,015	128,400	SH	Call	SOLE		128,400	0	0
BLUEPRINT MEDICINES CORP	COM	09627Y109	31,200	400,000	SH	Put	SOLE		400,000	0	0
BRIDGEBIO PHARMA INC	COM	10806X102	1,027	31,500	SH	Call	SOLE		31,500	0	0
BRISTOL-MYERS SQUIBB CO	RIGHT 99/99/9999	110122157	3,938	1,100,000	SH		SOLE		1,100,000	0	0
CARA THERAPEUTICS INC	COM	140755109	335	19,600	SH	Call	SOLE		19,600	0	0
CARA THERAPEUTICS INC	COM	140755109	4,677	273,524	SH		SOLE		273,524	0	0
CASI PHARMACEUTICALS INC	COM	14757U109	2,600	1,039,910	SH		SOLE		1,039,910	0	0
CEL SCI CORP	COM PAR NEW	150837607	9,514	637,700	SH	Put	SOLE		637,700	0	0
CELLDEX THERAPEUTICS INC NEW	COM NEW	15117B202	3,569	274,500	SH	Call	SOLE		274,500	0	0
CELLDEX THERAPEUTICS INC NEW	COM NEW	15117B202	21,417	1,647,439	SH		SOLE		1,647,439	0	0
CELLECTIS S A	SPON ADS	15117K103	1,301	73,067	SH		SOLE		73,067	0	0
CERECOR INC	COM	15671L109	1,047	402,865	SH		SOLE		402,865	0	0
CHARDAN HEALTHCR ACQSTN 2 CO	UNIT 99/99/9999	15957T206	4,200	400,000	SH		SOLE		400,000	0	0
CHEMOCENTRYX INC	COM	16383L106	28,770	500,000	SH	Put	SOLE		500,000	0	0
CHIASMA INC	COM	16706W102	7,691	1,429,633	SH		SOLE		1,429,633	0	0
CLOVIS ONCOLOGY INC	COM	189464100	3,219	476,900	SH	Call	SOLE		476,900	0	0
CLOVIS ONCOLOGY INC	COM	189464100	101	14,918	SH		SOLE		14,918	0	0
CORBUS PHARMACEUTICALS HLDGS	COM	21833P103	11,327	1,350,000	SH	Put	SOLE		1,350,000	0	0
CORBUS PHARMACEUTICALS HLDGS	COM	21833P103	8,390	1,000,000	SH	Call	SOLE		1,000,000	0	0
CRISPR THERAPEUTICS AG	NAMEN AKT	H17182108	13,162	179,100	SH	Put	SOLE		179,100	0	0
CYMABAY THERAPEUTICS INC	COM	23257D103	5,339	1,529,830	SH		SOLE		1,529,830	0	0
DBV TECHNOLOGIES S A	SPONSORED ADR	23306J101	723	164,730	SH		SOLE		164,730	0	0
DECIPHERA PHARMACEUTICALS IN	COM	24344T101	5,972	100,000	SH	Put	SOLE		100,000	0	0
DELCATH SYS INC	COM NEW	24661P807	964	94,000	SH		SOLE		94,000	0	0
DICERNA PHARMACEUTICALS INC	COM	253031108	254	10,000	SH	Put	SOLE		10,000	0	0
DICERNA PHARMACEUTICALS INC	COM	253031108	648	25,500	SH	Call	SOLE		25,500	0	0
EIDOS THERAPEUTICS INC	COM	28249H104	4,767	100,000	SH		SOLE		100,000	0	0
FATE THERAPEUTICS INC	COM	31189P102	1,719	50,100	SH	Put	SOLE		50,100	0	0
FATE THERAPEUTICS INC	COM	31189P102	1,719	50,100	SH	Call	SOLE		50,100	0	0
FIBROGEN INC	COM	31572Q808	8,106	200,000	SH	Call	SOLE		200,000	0	0
FIBROGEN INC	COM	31572Q808	3,242	80,000	SH	Put	SOLE		80,000	0	0
GENFIT S A	ADS	372279109	353	64,027	SH		SOLE		99,750	0	0
GILEAD SCIENCES INC	COM	375558103	478	6,218	SH		SOLE		6,218	0	0
GLOBAL BLOOD THERAPEUTICS IN	COM	37890U108	14,520	230,000	SH	Call	SOLE		230,000	0	0
GLOBAL BLOOD THERAPEUTICS IN	COM	37890U108	6,446	102,100	SH	Put	SOLE		102,100	0	0
GOSSAMER BIO INC	COM	38341P102	9,152	703,999	SH		SOLE		703,999	0	0
HORIZON THERAPEUTICS PUB LTD	SHS USD	G16411810	2,092	37,641	SH		SOLE		37,641	0	0
HORIZON THERAPEUTICS PUB LTD	SHS USD	G16411810	13,700	246,500	SH	Call	SOLE		246,500	0	0
ICAD INC	COM NEW	44934S206	3,120	312,268	SH		SOLE		312,268	0	0
IMMUNOMEDICS INC	COM	452907108	571	16,100	SH	Call	SOLE		16,100	0	0
IMMUNOVANT INC	COM	45258J102	6,871	282,163	SH		SOLE		282,163	0	0
INCYTE CORP	COM	45337C102	15,596	150,000	SH	Call	SOLE		150,000	0	0
INCYTE CORP	COM	45337C102	385	3,700	SH		SOLE		3,700	0	0
INFLARX NV	COM	N44821101	700	152,600	SH		SOLE		152,600	0	0
INSMED INC	COM PAR $.01	457669307	80	2,919	SH		SOLE		2,919	0	0
INTERCEPT PHARMACEUTICALS IN	COM	45845P108	1,701	35,500	SH	Put	SOLE		35,500	0	0
INTERCEPT PHARMACEUTICALS IN	COM	45845P108	7,187	150,000	SH	Call	SOLE		150,000	0	0
INTRA CELLULAR THERAPIES INC	COM	46116X101	185	7,202	SH		SOLE		7,202	0	0
INTRA CELLULAR THERAPIES INC	COM	46116X101	11,790	459,300	SH	Call	SOLE		459,300	0	0
INVESCO QQQ TR	UNIT SER 1	46090E103	30,950	125,000	SH	Call	SOLE		125,000	0	0
ISHARES TR	CHINA LG-CAP ETF	464287184	23,820	600,000	SH	Put	SOLE		600,000	0	0
ISHARES TR	RUSSELL 2000 ETF	464287655	165	1,154	SH		SOLE		1,154	0	0
KADMON HLDGS INC	COM	48283N106	5,023	981,070	SH		SOLE		981,070	0	0
KALVISTA PHARMACEUTICALS INC	COM	483497103	13,472	1,113,395	SH		SOLE		1,113,395	0	0
KINIKSA PHARMACEUTICALS LTD	COM CL A	G5269C101	720	28,274	SH		SOLE		28,274	0	0
KURA ONCOLOGY INC	COM	50127T109	7,590	465,619	SH		SOLE		465,619	0	0
KURA ONCOLOGY INC	COM	50127T109	2,445	150,000	SH	Call	SOLE		150,000	0	0
LEGEND BIOTECH CORP	SPONSORED ADS	52490G102	213	5,000	SH		SOLE		5,000	0	0
MADRIGAL PHARMACEUTICALS INC	COM	558868105	9,592	84,700	SH	Call	SOLE		84,700	0	0
MADRIGAL PHARMACEUTICALS INC	COM	558868105	4,819	42,554	SH		SOLE		42,554	0	0
MAGENTA THERAPEUTICS INC	COM	55910K108	65	8,674	SH		SOLE		8,674	0	0
MEDICAL PPTYS TRUST INC	COM	58463J304	11,280	600,000	SH	Put	SOLE		600,000	0	0
MILLENDO THERAPEUTICS INC	COM	60040X103	238	135,193	SH		SOLE		135,193	0	0
MINERVA NEUROSCIENCES INC	COM	603380106	2,316	641,600	SH	Call	SOLE		641,600	0	0
MINERVA NEUROSCIENCES INC	COM	603380106	1,250	346,300	SH	Put	SOLE		346,300	0	0
MIRATI THERAPEUTICS INC	COM	60468T105	17,126	150,000	SH	Put	SOLE		150,000	0	0
MODERNA INC	COM	60770K107	1,926	30,000	SH	Call	SOLE		30,000	0	0
MODERNA INC	COM	60770K107	19,263	300,000	SH	Put	SOLE		300,000	0	0
MUSTANG BIO INC	COM	62818Q104	1,134	356,475	SH		SOLE		356,475	0	0
MYOKARDIA INC	COM	62857M105	17,450	180,600	SH	Put	SOLE		180,600	0	0
MYOVANT SCIENCES LTD	COM	G637AM102	536	25,999	SH		SOLE		25,999	0	0
NEKTAR THERAPEUTICS	COM	640268108	3,474	150,000	SH	Call	SOLE		150,000	0	0
NOVAVAX INC	COM	670002901	13,694	164,300	SH	Put	SOLE		164,300	0	0
OBSEVA SA	COM	H5861P103	486	82,573	SH		SOLE		82,573	0	0
OCULAR THERAPEUTIX INC	COM	67576A100	17,126	2,055,977	SH		SOLE		2,055,977	0	0
OMEGA HEALTHCARE INVS INC	COM	681936100	14,865	500,000	SH	Put	SOLE		500,000	0	0
OTONOMY INC	COM	68906L105	1,086	300,000	SH	Call	SOLE		300,000	0	0
OTONOMY INC	COM	68906L105	3,864	1,067,271	SH		SOLE		1,067,271	0	0
PRECISION BIOSCIENCES INC	COM	74019P108	73	8,812	SH		SOLE		8,812	0	0
PROTARA THERAPEUTICS INC	COM STK	74365U107	15,480	527,964	SH		SOLE		527,964	0	0
PUMA BIOTECHNOLOGY INC	COM	74587V107	573	54,901	SH		SOLE		54,901	0	0
REATA PHARMACEUTICALS INC	CL A	75615P103	13,059	83,700	SH	Put	SOLE		83,700	0	0
REATA PHARMACEUTICALS INC	CL A	75615P103	26,071	167,100	SH	Call	SOLE		167,100	0	0
RESTORBIO INC	COM	76133L103	3,123	1,452,551	SH		SOLE		1,452,551	0	0
RIGEL PHARMACEUTICALS INC	COM NEW	766559603	3,075	1,680,529	SH		SOLE		1,680,529	0	0
SAGE THERAPEUTICS INC	COM	78667J108	8,364	201,151	SH		SOLE		201,151	0	0
SAGE THERAPEUTICS INC	COM	78667J108	9,534	229,300	SH	Call	SOLE		229,300	0	0
SAREPTA THERAPEUTICS INC	COM	803607100	417	2,600	SH	Call	SOLE		2,600	0	0
SATSUMA PHARMACEUTICALS INC	COM	80405P107	9,457	328,824	SH		SOLE		328,824	0	0
SCPHARMACEUTICALS INC	COM	810648105	10,809	1,468,647	SH		SOLE		1,468,647	0	0
SELECT SECTOR SPDR TR	ENERGY	81369Y506	9,201	243,100	SH	Put	SOLE		243,100	0	0
SELECT SECTOR SPDR TR	SBI INT-FINL	81369Y605	13,884	600,000	SH	Put	SOLE		600,000	0	0
SERES THERAPEUTICS INC	COM	81750R102	1,677	352,300	SH	Put	SOLE		352,300	0	0
SERES THERAPEUTICS INC	COM	81750R102	1,190	250,000	SH	Call	SOLE		250,000	0	0
SIERRA ONCOLOGY INC	COM NEW	82640U404	118	9,658	SH		SOLE		9,658	0	0
SOLENO THERAPEUTICS INC	COM NEW	834203200	748	336,801	SH		SOLE		336,801	0	0
SOLENO THERAPEUTICS INC	COM NEW	834203200	2,331	1,050,000	SH	Call	SOLE		1,050,000	0	0
SOLENO THERAPEUTICS INC	COM NEW	834203200	2,617	1,178,800	SH	Put	SOLE		1,178,800	0	0
SOLID BIOSCIENCES INC	COM	83422E105	2,309	788,008	SH		SOLE		788,008	0	0
SPDR S&P 500 ETF TR	TR UNIT	78462F103	215,852	700,000	SH	Put	SOLE		700,000	0	0
SPDR SER TR	S&P BIOTECH	78464A870	27,988	250,000	SH	Put	SOLE		250,000	0	0
STEALTH BIOTHERAPEUTICS CORP	SPONSORED ADS	85789A105	69	37,597	SH		SOLE		37,597	0	0
STRONGBRIDGE BIOPHARMA PLC	SHS USD	G85347105	12,365	3,271,238	SH		SOLE		3,271,238	0	0
SUNESIS PHARMACEUTICALS INC	COM	867328700	29	111,445	SH		SOLE		111,445	0	0
SYNDAX PHARMACEUTICALS INC	COM	87164F105	237	16,000	SH		SOLE		16,000	0	0
TRICIDA INC	COM	89610F101	4,864	177,002	SH		SOLE		177,002	0	0
ULTRAGENYX PHARMACEUTICAL IN	COM	90400D108	181	2,313	SH		SOLE		2,313	0	0
ULTRAGENYX PHARMACEUTICAL IN	COM	90400D108	5,749	73,500	SH	Call	SOLE		73,500	0	0
VANGUARD INDEX FDS	REAL ESTATE ETF	922908553	19,633	250,000	SH	Put	SOLE		250,000	0	0
VAXCYTE INC	COM	92243G108	4,419	139,813	SH		SOLE		139,813	0	0
VERASTEM INC	COM	92337C104	3,291	1,913,327	SH		SOLE		1,913,327	0	0
VIKING THERAPEUTICS INC	COM	92686J106	8	1,159	SH		SOLE		1,159	0	0
X4 PHARMACEUTICALS INC	COM	98420X103	47	5,000	SH		SOLE		5,000	0	0
XENON PHARMACEUTICALS INC	COM	98420N105	3,739	298,173	SH		SOLE		298,173	0	0
ZOGENIX INC	COM NEW	98978L204	13,709	507,559	SH		SOLE		507,559	0	0
ZOGENIX INC	COM NEW	98978L204	3,314	122,700	SH	Call	SOLE		122,700	0	0
ZOGENIX INC	COM NEW	98978L204	11,865	439,300	SH	Put	SOLE		439,300	0	0
ZYMEWORKS INC	COM	98985W102	7,676	212,800	SH	Put	SOLE		212,800	0	0
ZYMEWORKS INC	COM	98985W102	25,249	700,000	SH	Call	SOLE		700,000	0	0
ZYNERBA PHARMACEUTICALS INC	COM	98986X109	2,182	647,400	SH		SOLE		647,400	0	0
ZYNERBA PHARMACEUTICALS INC	COM	98986X109	2,334	692,500	SH	Put	SOLE		692,500	0	0
ZYNERBA PHARMACEUTICALS INC	COM	98986X109	3,240	961,400	SH	Call	SOLE		961,400	0	0