Ikarian Capital 13F-HR Quarterly holdings report by institutional manager

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL

OMB Number:		3235-0006
Expires:	Oct 31, 2018
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COLUMN 1	COLUMN 2	COLUMN 3	COLUMN 4	COLUMN 5			COLUMN 6	COLUMN 7	COLUMN 8
			VALUE	SHRS OR	SH/	PUT/	INVESTMENT	OTHER	VOTING AUTHORITY
NAME OF ISSUER	TITLE OF CLASS	CUSIP	(x$1000)	PRN AMT	PRN	CALL	DISCRETION	MANAGER	SOLE	SHARED	NONE
89BIO INC	COM	282559103	8,730	340,236	SH		SOLE		340,236	0	0
ACADIA PHARMACEUTICALS INC	COM	004225108	2,310	56,008	SH		SOLE		56,008	0	0
ACADIA PHARMACEUTICALS INC	COM	004225108	4,126	100,000	SH	Put	SOLE		100,000	0	0
ACHIEVE LIFE SCIENCES INC	COM	004468500	2,379	284,151	SH		SOLE		284,151	0	0
ADICET BIO INC	COM	007002108	3,261	274,277	SH		SOLE		274,277	0	0
ADMA BIOLOGICS INC	COM	000899104	478	200,000	SH		SOLE		200,000	0	0
ADVERUM BIOTECHNOLOGIES INC	COM	00773U108	4,155	403,400	SH	Call	SOLE		403,400	0	0
ADVERUM BIOTECHNOLOGIES INC	COM	00773U108	3,036	294,800	SH	Put	SOLE		294,800	0	0
AERPIO PHARMACEUTICALS INC	COM	00810B105	5,914	3,942,460	SH		SOLE		3,942,460	0	0
AGENUS INC	COM NEW	00847G705	3,800	950,000	SH		SOLE		950,000	0	0
AIMMUNE THERAPEUTICS INC	COM	00900T107	11,248	326,500	SH	Put	SOLE		326,500	0	0
AIR LEASE CORP	CL A	00912X302	518	17,600	SH	Put	SOLE		17,600	0	0
ALECTOR INC	COM	014442107	3	321	SH		SOLE		321	0	0
ALNYLAM PHARMACEUTICALS INC	COM	02043Q107	7,280	50,000	SH	Put	SOLE		50,000	0	0
ALPINE IMMUNE SCIENCES INC	COM	02083G100	41	4,739	SH		SOLE		4,739	0	0
ALTIMMUNE INC	COM NEW	02155H200	1,502	113,768	SH		SOLE		113,768	0	0
ANAPTYSBIO INC	COM	032724106	738	50,000	SH		SOLE		50,000	0	0
APELLIS PHARMACEUTICALS INC	COM	03753U106	565	18,726	SH		SOLE		18,726	0	0
APPLIED GENETIC TECHNOLOGIES	COM	03820J100	2,654	545,884	SH		SOLE		545,884	0	0
APTINYX INC	COM	03836N103	1,675	495,490	SH		SOLE		495,490	0	0
APTOSE BIOSCIENCES INC	COM NEW	03835T200	23	3,904	SH		SOLE		3,904	0	0
ARBUTUS BIOPHARMA CORP	COM	03879J100	360	115,000	SH		SOLE		115,000	0	0
ARDELYX INC	COM	039697107	8,036	1,530,436	SH		SOLE		1,530,436	0	0
ARENA PHARMACEUTICALS INC	COM NEW	040047607	373	5,000	SH		SOLE		5,000	0	0
ARENA PHARMACEUTICALS INC	COM NEW	040047607	19,446	260,000	SH	Call	SOLE		260,000	0	0
ARGENX SE	SPONSORED ADR	04016X101	209	800	SH	Put	SOLE		800	0	0
ARROWHEAD PHARMACEUTICALS IN	COM	04280A100	6,459	150,000	SH	Call	SOLE		150,000	0	0
ARVINAS INC	COM	04335A105	3,771	159,700	SH	Call	SOLE		159,700	0	0
ARYA SCIENCES ACQUISTION CO	UNIT 06/09/2027	G31655114	3,501	318,206	SH		SOLE		318,206	0	0
ASCENDIS PHARMA A/S	SPONSORED ADR	04351P101	22,376	145,000	SH	Call	SOLE		145,000	0	0
ASSEMBLY BIOSCIENCES INC	COM	045396108	2,589	157,468	SH		SOLE		157,468	0	0
ATARA BIOTHERAPEUTICS INC	COM	046513107	5,531	426,800	SH		SOLE		426,800	0	0
AURINIA PHARMACEUTICALS INC	COM	05156V102	1,474	100,000	SH	Call	SOLE		100,000	0	0
AVADEL PHARMACEUTICALS PLC	SPONSORED ADR	05337M104	275	54,694	SH		SOLE		54,694	0	0
AVROBIO INC	COM	05455M100	1,628	125,000	SH		SOLE		125,000	0	0
AXOVANT SCIENCES LTD	COM	G0750W203	820	177,684	SH		SOLE		177,684	0	0
BAUDAX BIO INC	COM	07160F107	277	100,000	SH		SOLE		100,000	0	0
BCTG ACQUISITION CORP	COM	05492W103	2	250	SH		SOLE		250	0	0
BELLUS HEALTH INC NEW	COM NEW	07987C204	227	100,000	SH		SOLE		100,000	0	0
BIOGEN INC	COM	09062X103	852	3,000	SH		SOLE		3,000	0	0
BIOGEN INC	COM	09062X103	39,375	138,800	SH	Put	SOLE		138,800	0	0
BIOGEN INC	COM	09062X103	28,368	100,000	SH	Call	SOLE		100,000	0	0
BIOXCEL THERAPEUTICS INC	COM	09075P105	6,504	150,000	SH	Call	SOLE		150,000	0	0
BIOXCEL THERAPEUTICS INC	COM	09075P105	117	2,714	SH		SOLE		2,714	0	0
BLACK DIAMOND THERAPEUTICS I	COM	09203E105	10,851	358,941	SH		SOLE		358,941	0	0
BLUEBIRD BIO INC	COM	09609G100	2,173	40,281	SH		SOLE		40,281	0	0
BRAINSTORM CELL THERAPEUTICS	COM NEW	10501E201	19,797	1,170,100	SH	Put	SOLE		1,170,100	0	0
BRISTOL-MYERS SQUIBB CO	RIGHT 99/99/9999	110122157	4,050	1,800,000	SH		SOLE		1,800,000	0	0
BRISTOL-MYERS SQUIBB CO	COM	110122108	18,087	300,000	SH	Call	SOLE		300,000	0	0
BRISTOL-MYERS SQUIBB CO	COM	110122108	6,028	100,000	SH		SOLE		100,000	0	0
CARA THERAPEUTICS INC	COM	140755109	3,481	273,524	SH		SOLE		273,524	0	0
CARA THERAPEUTICS INC	COM	140755109	738	58,000	SH	Call	SOLE		58,000	0	0
CASI PHARMACEUTICALS INC	COM	14757U109	2,356	1,539,910	SH		SOLE		1,539,910	0	0
CELLDEX THERAPEUTICS INC NEW	COM NEW	15117B202	21,796	1,469,730	SH		SOLE		1,469,730	0	0
CELLDEX THERAPEUTICS INC NEW	COM NEW	15117B202	946	63,800	SH	Call	SOLE		63,800	0	0
CERECOR INC	COM	15671L109	460	202,865	SH		SOLE		202,865	0	0
CHARDAN HEALTHCR ACQSTN 2 CO	UNIT 99/99/9999	15957T206	4,221	400,000	SH		SOLE		400,000	0	0
CHEMOCENTRYX INC	COM	16383L106	5,480	100,000	SH	Call	SOLE		100,000	0	0
CHEMOCENTRYX INC	COM	16383L106	1	37	SH		SOLE		37	0	0
CHIASMA INC	COM	16706W102	7,008	1,629,633	SH		SOLE		1,629,633	0	0
CHIMERIX INC	COM	16934W106	3,397	1,364,044	SH		SOLE		1,364,044	0	0
CLOVIS ONCOLOGY INC	COM	189464100	4,408	756,236	SH		SOLE		756,236	0	0
CLOVIS ONCOLOGY INC	COM	189464100	2,332	400,000	SH	Call	SOLE		400,000	0	0
COMPASS PATHWAYS PLC	SPONSORED ADS	20451W101	5,342	153,048	SH		SOLE		153,048	0	0
CORBUS PHARMACEUTICALS HLDGS	COM	21833P103	397	220,100	SH	Call	SOLE		220,100	0	0
CORTEXYME INC	COM	22053A107	2,000	40,000	SH		SOLE		40,000	0	0
CORTEXYME INC	COM	22053A107	150	3,000	SH	Call	SOLE		3,000	0	0
CORTEXYME INC	COM	22053A107	150	3,000	SH	Put	SOLE		3,000	0	0
CRINETICS PHARMACEUTICALS IN	COM	22663K107	784	50,000	SH		SOLE		50,000	0	0
CRISPR THERAPEUTICS AG	NAMEN AKT	H17182108	9,644	115,300	SH	Put	SOLE		115,300	0	0
CRYOPORT INC	COM PAR $0.001	229050307	11,850	250,000	SH	Put	SOLE		250,000	0	0
CRYOPORT INC	COM PAR $0.001	229050307	12,935	272,900	SH	Call	SOLE		272,900	0	0
CYTOKINETICS INC	COM NEW	23282W605	1,190	55,000	SH		SOLE		55,000	0	0
CYTOKINETICS INC	COM NEW	23282W605	25,364	1,171,600	SH	Call	SOLE		1,171,600	0	0
CYTOKINETICS INC	COM NEW	23282W605	6,927	320,000	SH	Put	SOLE		320,000	0	0
DBV TECHNOLOGIES S A	SPONSORED ADR	23306J101	596	164,730	SH		SOLE		164,730	0	0
DECIPHERA PHARMACEUTICALS IN	COM	24344T101	7,183	140,000	SH	Call	SOLE		140,000	0	0
DECIPHERA PHARMACEUTICALS IN	COM	24344T101	5,131	100,000	SH	Put	SOLE		100,000	0	0
DELCATH SYS INC	COM NEW	24661P807	1,092	94,000	SH		SOLE		94,000	0	0
DIAMEDICA THERAPEUTICS INC	COM NEW	25253X207	1,759	415,000	SH		SOLE		415,000	0	0
DICERNA PHARMACEUTICALS INC	COM	253031108	179	10,000	SH	Put	SOLE		10,000	0	0
DICERNA PHARMACEUTICALS INC	COM	253031108	179	10,000	SH	Call	SOLE		10,000	0	0
EIDOS THERAPEUTICS INC	COM	28249H104	3,184	63,011	SH		SOLE		63,011	0	0
EIGER BIOPHARMACEUTICALS INC	COM	28249U105	2,771	340,318	SH		SOLE		340,318	0	0
EPIZYME INC	COM	29428V104	347	29,080	SH		SOLE		29,080	0	0
FATE THERAPEUTICS INC	COM	31189P102	2,003	50,100	SH	Put	SOLE		50,100	0	0
FATE THERAPEUTICS INC	COM	31189P102	2,003	50,100	SH	Call	SOLE		50,100	0	0
FIBROGEN INC	COM	31572Q808	8,222	200,000	SH	Call	SOLE		200,000	0	0
FIBROGEN INC	COM	31572Q808	8,301	201,900	SH	Put	SOLE		201,900	0	0
GLOBAL BLOOD THERAPEUTICS IN	COM	37890U108	117	2,100	SH	Put	SOLE		2,100	0	0
GOSSAMER BIO INC	COM	38341P102	1,009	81,300	SH	Call	SOLE		81,300	0	0
GOSSAMER BIO INC	COM	38341P102	7,229	582,494	SH		SOLE		582,494	0	0
HARROW HEALTH INC	COM	415858109	2,563	458,607	SH		SOLE		458,607	0	0
HORIZON THERAPEUTICS PUB L	SHS	G46188101	205	2,641	SH		SOLE		2,641	0	0
HORIZON THERAPEUTICS PUB L	SHS	G46188101	30,023	386,500	SH	Call	SOLE		386,500	0	0
HOST HOTELS & RESORTS INC	COM	44107P104	4,317	400,000	SH	Put	SOLE		400,000	0	0
I MAB	SPONSORED ADS	44975P103	7,054	150,000	SH		SOLE		150,000	0	0
ICAD INC	COM NEW	44934S206	1,596	181,337	SH		SOLE		181,337	0	0
IGM BIOSCIENCES INC	COM	449585108	23,124	313,300	SH	Put	SOLE		313,300	0	0
IGM BIOSCIENCES INC	COM	449585108	18,452	250,000	SH	Call	SOLE		250,000	0	0
IMMATICS N.V	SHS	N44445109	6,770	638,094	SH		SOLE		638,094	0	0
IMMUNOMEDICS INC	COM	452907108	1,369	16,100	SH	Call	SOLE		16,100	0	0
IMMUNOVANT INC	COM	45258J102	11,328	321,887	SH		SOLE		321,887	0	0
INCYTE CORP	COM	45337C102	8,974	100,000	SH	Put	SOLE		100,000	0	0
INCYTE CORP	COM	45337C102	13,461	150,000	SH	Call	SOLE		150,000	0	0
INFLARX NV	COM	N44821101	637	149,750	SH		SOLE		149,750	0	0
INTRA CELLULAR THERAPIES INC	COM	46116X101	6,415	250,000	SH	Call	SOLE		250,000	0	0
INTRA CELLULAR THERAPIES INC	COM	46116X101	2,567	100,000	SH	Put	SOLE		100,000	0	0
INTRA CELLULAR THERAPIES INC	COM	46116X101	6,183	240,989	SH		SOLE		240,989	0	0
INVENTIVA SA	ADS	46124U107	177	15,000	SH		SOLE		15,000	0	0
KADMON HLDGS INC	COM	48283N106	3,673	936,615	SH		SOLE		936,615	0	0
KALA PHARMACEUTICALS INC	COM	483119103	3,387	451,531	SH		SOLE		451,531	0	0
KALVISTA PHARMACEUTICALS INC	COM	483497103	15,554	1,235,471	SH		SOLE		1,235,471	0	0
KINIKSA PHARMACEUTICALS LTD	COM CL A	G5269C101	5,254	342,998	SH		SOLE		342,998	0	0
KODIAK SCIENCES INC	COM	50015M109	14,802	250,000	SH	Put	SOLE		250,000	0	0
KURA ONCOLOGY INC	COM	50127T109	189	6,203	SH		SOLE		6,203	0	0
KURA ONCOLOGY INC	COM	50127T109	6,721	219,400	SH	Call	SOLE		219,400	0	0
LIFESCI ACQUISITION CORP	COM	53228P109	2,999	241,762	SH		SOLE		241,762	0	0
LYRA THERAPEUTICS INC	COM	55234L105	4,338	387,939	SH		SOLE		387,939	0	0
MADRIGAL PHARMACEUTICALS INC	COM	558868105	13,642	114,900	SH	Call	SOLE		114,900	0	0
MADRIGAL PHARMACEUTICALS INC	COM	558868105	2,809	23,654	SH		SOLE		23,654	0	0
MEDICAL PPTYS TRUST INC	COM	58463J304	10,579	600,000	SH	Put	SOLE		600,000	0	0
MEREO BIOPHARMA GROUP PLC	ADS	589492107	688	1,196,308	SH		SOLE		1,196,308	0	0
MESOBLAST LTD	SPONS ADR	590717104	145	7,800	SH	Put	SOLE		7,800	0	0
MILESTONE PHARMACEUTICALS IN	COM	59935V107	12,764	1,743,545	SH		SOLE		1,743,545	0	0
MILLENDO THERAPEUTICS INC	COM	60040X103	220	135,193	SH		SOLE		135,193	0	0
MIRATI THERAPEUTICS INC	COM	60468T105	91,161	549,000	SH	Put	SOLE		549,000	0	0
MIRATI THERAPEUTICS INC	COM	60468T105	6,402	38,557	SH		SOLE		38,557	0	0
MODERNA INC	COM	60770K107	77,394	1,093,900	SH	Put	SOLE		1,093,900	0	0
MUSTANG BIO INC	COM	62818Q104	2,541	806,475	SH		SOLE		806,475	0	0
MYOVANT SCIENCES LTD	COM	G637AM102	2,810	200,000	SH	Call	SOLE		200,000	0	0
NEKTAR THERAPEUTICS	COM	640268108	2,488	150,000	SH	Call	SOLE		150,000	0	0
NEXTCURE INC	COM	65343E108	1,760	200,000	SH		SOLE		200,000	0	0
NOVAVAX INC	COM NEW	670002401	40,675	375,400	SH	Put	SOLE		375,400	0	0
NOVAVAX INC	COM NEW	670002401	286	2,636	SH		SOLE		2,636	0	0
OCULAR THERAPEUTIX INC	COM	67576A100	13,061	1,716,293	SH		SOLE		1,716,293	0	0
OTONOMY INC	COM	68906L105	1,761	434,786	SH		SOLE		434,786	0	0
OVID THERAPEUTICS INC	COM	690469101	92	16,000	SH	Call	SOLE		16,000	0	0
PANDION THERAPEUTICS INC	COM	698340106	2,978	260,000	SH		SOLE		260,000	0	0
POSEIDA THERAPEUTICS INC	COM	73730P108	2,022	228,000	SH		SOLE		228,000	0	0
PRECISION BIOSCIENCES INC	COM	74019P108	55	8,812	SH		SOLE		8,812	0	0
PROTARA THERAPEUTICS INC	COM STK	74365U107	12,158	722,443	SH		SOLE		722,443	0	0
PROTEOSTASIS THERAPEUTICS IN	COM	74373B109	2,628	2,389,891	SH		SOLE		2,389,891	0	0
PUMA BIOTECHNOLOGY INC	COM	74587V107	554	54,901	SH		SOLE		54,901	0	0
RAPT THERAPEUTICS INC	COM	75382E109	503	15,600	SH	Put	SOLE		15,600	0	0
RAPT THERAPEUTICS INC	COM	75382E109	170	5,300	SH	Call	SOLE		5,300	0	0
REATA PHARMACEUTICALS INC	CL A	75615P103	5,592	57,400	SH	Put	SOLE		57,400	0	0
REATA PHARMACEUTICALS INC	CL A	75615P103	11,408	117,100	SH	Call	SOLE		117,100	0	0
REPARE THERAPEUTICS INC	COM	760273102	5,858	190,410	SH		SOLE		190,410	0	0
RIGEL PHARMACEUTICALS INC	COM NEW	766559603	1,668	695,529	SH		SOLE		695,529	0	0
SAGE THERAPEUTICS INC	COM	78667J108	7,099	116,151	SH		SOLE		116,151	0	0
SAGE THERAPEUTICS INC	COM	78667J108	4,847	79,300	SH	Call	SOLE		79,300	0	0
SAREPTA THERAPEUTICS INC	COM	803607100	74,441	530,100	SH	Put	SOLE		530,100	0	0
SAREPTA THERAPEUTICS INC	COM	803607100	14,407	102,600	SH	Call	SOLE		102,600	0	0
SCPHARMACEUTICALS INC	COM	810648105	11,033	1,481,147	SH		SOLE		1,481,147	0	0
SERES THERAPEUTICS INC	COM	81750R102	21,585	762,400	SH	Call	SOLE		762,400	0	0
SERES THERAPEUTICS INC	COM	81750R102	2,701	95,430	SH		SOLE		95,430	0	0
SIERRA ONCOLOGY INC	COM NEW	82640U404	3,350	313,890	SH		SOLE		313,890	0	0
SOLID BIOSCIENCES INC	COM	83422E105	1,600	788,008	SH		SOLE		788,008	0	0
SPDR S&P 500 ETF TR	TR UNIT	78462F103	66,977	200,000	SH	Put	SOLE		200,000	0	0
SPDR SER TR	S&P BIOTECH	78464A870	94,716	850,000	SH	Put	SOLE		850,000	0	0
STEALTH BIOTHERAPEUTICS CORP	SPONSORED ADS	85789A105	50	37,597	SH		SOLE		37,597	0	0
STRONGBRIDGE BIOPHARMA PLC	SHS USD	G85347105	7,061	3,362,242	SH		SOLE		3,362,242	0	0
SUTRO BIOPHARMA INC	COM	869367102	4,904	488,000	SH		SOLE		488,000	0	0
TRACON PHARMACEUTICALS INC	COM NEW	89237H209	11,180	2,162,549	SH		SOLE		2,162,549	0	0
TRICIDA INC	COM	89610F101	210	23,193	SH		SOLE		23,193	0	0
VAXCYTE INC	COM	92243G108	796	16,110	SH		SOLE		16,110	0	0
VERASTEM INC	COM	92337C104	1,710	1,413,327	SH		SOLE		1,413,327	0	0
X4 PHARMACEUTICALS INC	COM	98420X103	4,907	724,680	SH		SOLE		724,680	0	0
XENON PHARMACEUTICALS INC	COM	98420N105	2,470	223,173	SH		SOLE		223,173	0	0
ZOGENIX INC	COM NEW	98978L204	16,137	900,000	SH	Call	SOLE		900,000	0	0
ZOGENIX INC	COM NEW	98978L204	3,274	182,591	SH		SOLE		182,591	0	0
ZYMEWORKS INC	COM	98985W102	23,290	500,000	SH	Call	SOLE		500,000	0	0
ZYMEWORKS INC	COM	98985W102	11,414	245,000	SH	Put	SOLE		245,000	0	0