Ikarian Capital 13F-HR Quarterly holdings report by institutional manager

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL

OMB Number:		3235-0006
Expires:	Oct 31, 2018
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COLUMN 1	COLUMN 2	COLUMN 3	COLUMN 4	COLUMN 5			COLUMN 6	COLUMN 7	COLUMN 8
			VALUE	SHRS OR	SH/	PUT/	INVESTMENT	OTHER	VOTING AUTHORITY
NAME OF ISSUER	TITLE OF CLASS	CUSIP	(x$1000)	PRN AMT	PRN	CALL	DISCRETION	MANAGER	SOLE	SHARED	NONE
89BIO INC	COM	282559103	799	32,799	SH		SOLE		32,799	0	0
ACADIA PHARMACEUTICALS INC	COM	004225108	2,995	56,008	SH		SOLE		56,008	0	0
ACCELERON PHARMA INC	COM	00434H108	12,793	100,000	SH	Put	SOLE		100,000	0	0
ACHIEVE LIFE SCIENCES INC	COM	004468500	2,302	284,151	SH		SOLE		284,151	0	0
ACLARIS THERAPEUTICS INC	COM	00461U105	1,527	235,800	SH	Call	SOLE		235,800	0	0
ACLARIS THERAPEUTICS INC	COM	00461U105	1,941	300,000	SH		SOLE		300,000	0	0
ADICET BIO INC	COM	007002108	2,449	174,277	SH		SOLE		174,277	0	0
ADVERUM BIOTECHNOLOGIES INC	COM	00773U108	2,804	258,700	SH	Call	SOLE		258,700	0	0
ADVERUM BIOTECHNOLOGIES INC	COM	00773U108	486	44,800	SH	Put	SOLE		44,800	0	0
AERPIO PHARMACEUTICALS INC	COM	00810B105	468	475,778	SH		SOLE		475,778	0	0
AGENUS INC	COM NEW	00847G705	3,020	950,000	SH		SOLE		950,000	0	0
AGIOS PHARMACEUTICALS INC	COM	00847X104	5,416	125,000	SH	Call	SOLE		125,000	0	0
ALBIREO PHARMA INC	COM	01345P106	633	16,883	SH		SOLE		16,883	0	0
ALECTOR INC	COM	014442107	870	57,500	SH		SOLE		57,500	0	0
ALLAKOS INC	COM	01671P100	8,218	58,700	SH	Call	SOLE		58,700	0	0
ALNYLAM PHARMACEUTICALS INC	COM	02043Q107	6,499	50,000	SH	Put	SOLE		50,000	0	0
ALPINE IMMUNE SCIENCES INC	COM	02083G100	60	4,739	SH		SOLE		4,739	0	0
ALTIMMUNE INC	COM NEW	02155H200	851	75,445	SH		SOLE		75,445	0	0
ANAPTYSBIO INC	COM	032724106	2,149	100,000	SH		SOLE		100,000	0	0
ANAPTYSBIO INC	COM	032724106	3,915	182,100	SH	Call	SOLE		182,100	0	0
APPLIED GENETIC TECHNOLOGIES	COM	03820J100	2,232	545,884	SH		SOLE		545,884	0	0
APPLIED THERAPEUTICS INC	COM	03828A101	726	33,002	SH		SOLE		33,002	0	0
APPLIED THERAPEUTICS INC	COM	03828A101	4,402	200,000	SH	Put	SOLE		200,000	0	0
APTOSE BIOSCIENCES INC	COM NEW	03835T200	18	3,904	SH		SOLE		3,904	0	0
ARBUTUS BIOPHARMA CORP	COM	03879J100	408	115,000	SH		SOLE		115,000	0	0
ARCTURUS THERAPEUTICS HLDGS	COM	03969T109	4,338	100,000	SH	Put	SOLE		100,000	0	0
ARCUS BIOSCIENCES INC	COM	03969F109	532	20,500	SH	Put	SOLE		20,500	0	0
ARDELYX INC	COM	039697107	7,476	1,155,436	SH		SOLE		1,155,436	0	0
ARENA PHARMACEUTICALS INC	COM NEW	040047607	3,265	42,500	SH	Call	SOLE		42,500	0	0
ARGENX SE	SPONSORED ADR	04016X101	59,260	201,500	SH	Put	SOLE		201,500	0	0
ARK ETF TR	GENOMIC REV ETF	00214Q302	41,044	440,100	SH	Put	SOLE		440,100	0	0
ARROWHEAD PHARMACEUTICALS IN	COM	04280A100	15,346	200,000	SH	Put	SOLE		200,000	0	0
ARVINAS INC	COM	04335A105	8,493	100,000	SH	Put	SOLE		100,000	0	0
ARVINAS INC	COM	04335A105	358	4,216	SH		SOLE		4,216	0	0
ARVINAS INC	COM	04335A105	19,763	232,700	SH	Call	SOLE		232,700	0	0
ASCENDIS PHARMA A/S	SPONSORED ADR	04351P101	8,456	50,700	SH	Call	SOLE		50,700	0	0
ASCENDIS PHARMA A/S	SPONSORED ADR	04351P101	14,526	87,090	SH		SOLE		87,090	0	0
ASLAN PHARMACEUTICALS LTD	ADS	04522R101	405	2,006,451	SH		SOLE		2,006,451	0	0
ASSEMBLY BIOSCIENCES INC	COM	045396108	439	72,468	SH		SOLE		72,468	0	0
ASTRAZENECA PLC	SPONSORED ADR	046353108	17,498	350,000	SH	Call	SOLE		350,000	0	0
ATYR PHARMA INC	COM NEW	002120202	1,552	400,000	SH		SOLE		400,000	0	0
AURINIA PHARMACEUTICALS INC	COM	05156V102	1,383	100,000	SH	Call	SOLE		100,000	0	0
AVADEL PHARMACEUTICALS PLC	SPONSORED ADR	05337M104	366	54,694	SH		SOLE		54,694	0	0
BAUDAX BIO INC	COM	07160F107	101	100,000	SH		SOLE		100,000	0	0
BCLS ACQUISITION CORP	COM CL A	G0904B105	1	100	SH		SOLE		100	0	0
BCTG ACQUISITION CORP	COM	05492W103	1,711	149,512	SH		SOLE		149,512	0	0
BEAM THERAPEUTICS INC	COM	07373V105	18,858	231,000	SH	Put	SOLE		231,000	0	0
BEIGENE LTD	SPONSORED ADR	07725L102	25,141	97,300	SH	Put	SOLE		97,300	0	0
BELLICUM PHARMACEUTICALS INC	COM NEW	079481404	1,765	500,000	SH		SOLE		500,000	0	0
BELLUS HEALTH INC NEW	COM NEW	07987C204	306	100,000	SH		SOLE		100,000	0	0
BIOGEN INC	COM	09062X103	88,148	360,000	SH	Put	SOLE		360,000	0	0
BIOGEN INC	COM	09062X103	1,396	5,700	SH		SOLE		5,700	0	0
BIOGEN INC	COM	09062X103	115,181	470,400	SH	Call	SOLE		470,400	0	0
BIOHAVEN PHARMACTL HLDG CO L	COM	G11196105	10,208	119,100	SH	Call	SOLE		119,100	0	0
BIOHAVEN PHARMACTL HLDG CO L	COM	G11196105	8,923	104,100	SH	Put	SOLE		104,100	0	0
BIONTECH SE	SPONSORED ADS	09075V102	26,080	319,900	SH	Put	SOLE		319,900	0	0
BIOXCEL THERAPEUTICS INC	COM	09075P105	6,930	150,000	SH	Call	SOLE		150,000	0	0
BLACK DIAMOND THERAPEUTICS I	COM	09203E105	9,421	293,941	SH		SOLE		293,941	0	0
BLUEBIRD BIO INC	COM	09609G100	12	281	SH		SOLE		281	0	0
BLUEBIRD BIO INC	COM	09609G100	4,595	106,200	SH	Call	SOLE		106,200	0	0
BLUEPRINT MEDICINES CORP	COM	09627Y109	13,457	120,000	SH	Put	SOLE		120,000	0	0
BRISTOL-MYERS SQUIBB CO	COM	110122108	17,890	288,400	SH		SOLE		288,400	0	0
BRISTOL-MYERS SQUIBB CO	RIGHT 99/99/9999	110122157	444	644,021	SH		SOLE		644,021	0	0
C4 THERAPEUTICS INC	COM STK	12529R107	5,019	151,500	SH		SOLE		151,500	0	0
CARA THERAPEUTICS INC	COM	140755109	4,565	301,700	SH	Call	SOLE		301,700	0	0
CARA THERAPEUTICS INC	COM	140755109	4,137	273,524	SH		SOLE		273,524	0	0
CARDIFF ONCOLOGY INC	COM	14147L108	7,517	417,900	SH	Put	SOLE		417,900	0	0
CASI PHARMACEUTICALS INC	COM	14757U109	3,741	1,268,154	SH		SOLE		1,268,154	0	0
CATABASIS PHARMACEUTICALS IN	COM NEW	14875P206	1,392	650,000	SH		SOLE		650,000	0	0
CELLDEX THERAPEUTICS INC NEW	COM NEW	15117B202	7,008	400,000	SH	Call	SOLE		400,000	0	0
CELLDEX THERAPEUTICS INC NEW	COM NEW	15117B202	23,915	1,364,990	SH		SOLE		1,364,990	0	0
CERECOR INC	COM	15671L109	536	202,865	SH		SOLE		202,865	0	0
CHARDAN HEALTHCR ACQSTN 2 CO	UNIT 99/99/9999	15957T206	4,236	400,000	SH		SOLE		400,000	0	0
CHEMBIO DIAGNOSTICS INC	COM NEW	163572209	1,041	219,109	SH		SOLE		219,109	0	0
CHEMOCENTRYX INC	COM	16383L106	27,969	451,700	SH	Put	SOLE		451,700	0	0
CHEMOCENTRYX INC	COM	16383L106	2	37	SH		SOLE		37	0	0
CHIASMA INC	COM	16706W102	3,177	730,299	SH		SOLE		730,299	0	0
CHIMERIX INC	COM	16934W106	5,953	1,232,513	SH		SOLE		1,232,513	0	0
CLOVIS ONCOLOGY INC	COM	189464100	3,121	650,000	SH	Call	SOLE		650,000	0	0
CLOVIS ONCOLOGY INC	COM	189464100	3,082	642,108	SH		SOLE		642,108	0	0
COGENT BIOSCIENCES INC	COM	19240Q201	469	41,762	SH		SOLE		41,762	0	0
COMPASS PATHWAYS PLC	SPONSORED ADS	20451W101	1,127	23,648	SH		SOLE		23,648	0	0
COMPASS PATHWAYS PLC	SPONSORED ADS	20451W101	8,947	187,800	SH	Call	SOLE		187,800	0	0
COMPUGEN LTD	ORD	M25722105	6	500	SH	Put	SOLE		500	0	0
CORBUS PHARMACEUTICALS HLDGS	COM	21833P103	174	139,100	SH		SOLE		139,100	0	0
CORTEXYME INC	COM	22053A107	776	28,000	SH	Call	SOLE		28,000	0	0
CORTEXYME INC	COM	22053A107	4,722	170,000	SH	Put	SOLE		170,000	0	0
CORTEXYME INC	COM	22053A107	361	13,000	SH		SOLE		13,000	0	0
CRISPR THERAPEUTICS AG	NAMEN AKT	H17182108	17,654	115,300	SH	Put	SOLE		115,300	0	0
CRYOPORT INC	COM PAR $0.001	229050307	10,970	250,000	SH	Call	SOLE		250,000	0	0
CRYOPORT INC	COM PAR $0.001	229050307	2,195	50,000	SH	Put	SOLE		50,000	0	0
CRYOPORT INC	COM PAR $0.001	229050307	1,004	22,900	SH		SOLE		22,900	0	0
CUREVAC N V	COM	N2451R105	21,175	261,200	SH	Put	SOLE		261,200	0	0
CURIS INC	COM NEW	231269200	4,198	512,500	SH	Call	SOLE		512,500	0	0
CURIS INC	COM NEW	231269200	12,899	1,575,000	SH		SOLE		1,575,000	0	0
CYCLACEL PHARMACEUTICALS INC	COM	23254L603	3,057	391,450	SH		SOLE		391,450	0	0
CYTOKINETICS INC	COM NEW	23282W605	3,116	150,000	SH	Call	SOLE		150,000	0	0
CYTOKINETICS INC	COM NEW	23282W605	4,718	227,000	SH		SOLE		227,000	0	0
DBV TECHNOLOGIES S A	SPONSORED ADR	23306J101	1,897	358,330	SH		SOLE		358,330	0	0
DECIPHERA PHARMACEUTICALS IN	COM	24344T101	7,989	140,000	SH	Call	SOLE		140,000	0	0
DELCATH SYS INC	COM NEW	24661P807	2,019	112,712	SH		SOLE		112,712	0	0
DIAMEDICA THERAPEUTICS INC	COM NEW	25253X207	4,208	415,000	SH		SOLE		415,000	0	0
EYEPOINT PHARMACEUTICALS INC	COM NEW	30233G209	119	17,900	SH	Call	SOLE		17,900	0	0
FATE THERAPEUTICS INC	COM	31189P102	3,500	38,500	SH	Call	SOLE		38,500	0	0
FATE THERAPEUTICS INC	COM	31189P102	3,529	38,800	SH	Put	SOLE		38,800	0	0
FIBROGEN INC	COM	31572Q808	9,343	251,900	SH	Put	SOLE		251,900	0	0
FIBROGEN INC	COM	31572Q808	11,126	300,000	SH	Call	SOLE		300,000	0	0
FREQUENCY THERAPEUTICS INC	COM	35803L108	3,028	85,900	SH	Put	SOLE		85,900	0	0
FS DEV CORP	COM CL A	303020101	3,850	350,000	SH		SOLE		350,000	0	0
FULCRUM THERAPEUTICS INC	COM	359616109	5,125	437,700	SH		SOLE		437,700	0	0
GAMIDA CELL LTD	SHS	M47364100	1,343	160,000	SH		SOLE		160,000	0	0
GILEAD SCIENCES INC	COM	375558103	17,478	300,000	SH	Call	SOLE		300,000	0	0
GLOBAL BLOOD THERAPEUTICS IN	COM	37890U108	91	2,100	SH	Put	SOLE		2,100	0	0
GLOBAL BLOOD THERAPEUTICS IN	COM	37890U108	8,663	200,000	SH	Call	SOLE		200,000	0	0
GOSSAMER BIO INC	COM	38341P102	10,138	1,048,383	SH		SOLE		1,048,383	0	0
GOSSAMER BIO INC	COM	38341P102	3,688	381,300	SH	Call	SOLE		381,300	0	0
GW PHARMACEUTICALS PLC	ADS	36197T103	2,204	19,100	SH	Put	SOLE		19,100	0	0
GW PHARMACEUTICALS PLC	ADS	36197T103	0	8	SH		SOLE		8	0	0
HARROW HEALTH INC	COM	415858109	2,117	308,607	SH		SOLE		308,607	0	0
HOMOLOGY MEDICINES INC	COM	438083107	1,129	100,000	SH	Put	SOLE		100,000	0	0
HORIZON THERAPEUTICS PUB L	SHS	G46188101	71,485	977,200	SH	Call	SOLE		977,200	0	0
HORIZON THERAPEUTICS PUB L	SHS	G46188101	19,385	265,000	SH	Put	SOLE		265,000	0	0
I MAB	SPONSORED ADS	44975P103	7,073	150,000	SH		SOLE		150,000	0	0
ICAD INC	COM NEW	44934S206	2,576	195,137	SH		SOLE		195,137	0	0
IGM BIOSCIENCES INC	COM	449585108	22,073	250,000	SH	Put	SOLE		250,000	0	0
IGM BIOSCIENCES INC	COM	449585108	27	300	SH		SOLE		300	0	0
IMMATICS N.V	SHS	N44445109	6,885	638,094	SH		SOLE		638,094	0	0
IMMUNOVANT INC	COM	45258J102	10,882	235,587	SH		SOLE		235,587	0	0
INFLARX NV	COM	N44821101	754	149,750	SH		SOLE		149,750	0	0
INHIBRX INC	COM	45720L107	266	8,076	SH		SOLE		8,076	0	0
INMUNE BIO INC	COM	45782T105	3,747	217,568	SH		SOLE		217,568	0	0
INTRA CELLULAR THERAPIES INC	COM	46116X101	8,934	280,989	SH		SOLE		280,989	0	0
INTRA CELLULAR THERAPIES INC	COM	46116X101	3,180	100,000	SH	Put	SOLE		100,000	0	0
INTRA CELLULAR THERAPIES INC	COM	46116X101	1,846	58,000	SH	Call	SOLE		58,000	0	0
INVENTIVA SA	ADS	46124U107	214	15,000	SH		SOLE		15,000	0	0
IONIS PHARMACEUTICALS INC	COM	462222100	16,397	290,000	SH	Call	SOLE		290,000	0	0
KADMON HLDGS INC	COM	48283N106	3,887	936,615	SH		SOLE		936,615	0	0
KALA PHARMACEUTICALS INC	COM	483119103	594	87,813	SH		SOLE		87,813	0	0
KALVISTA PHARMACEUTICALS INC	COM	483497103	2,761	145,500	SH	Call	SOLE		145,500	0	0
KALVISTA PHARMACEUTICALS INC	COM	483497103	20,204	1,063,961	SH		SOLE		1,063,961	0	0
KARUNA THERAPEUTICS INC	COM	48576A100	12,192	120,000	SH	Call	SOLE		120,000	0	0
KARYOPHARM THERAPEUTICS INC	COM	48576U106	12	791	SH		SOLE		791	0	0
KINIKSA PHARMACEUTICALS LTD	COM CL A	G5269C101	1,789	101,273	SH		SOLE		101,273	0	0
KINNATE BIOPHARMA INC	COM	49705R105	79	2,000	SH		SOLE		2,000	0	0
KURA ONCOLOGY INC	COM	50127T109	9,309	285,000	SH	Call	SOLE		285,000	0	0
KURA ONCOLOGY INC	COM	50127T109	366	11,203	SH		SOLE		11,203	0	0
LIFESCI ACQUISITION II CORP	COM	53229E103	5,363	505,000	SH		SOLE		505,000	0	0
LILLY ELI & CO	COM	532457108	16,884	100,000	SH	Call	SOLE		100,000	0	0
LIQUIDIA CORPORATION	COM NEW	53635D202	2,807	951,400	SH		SOLE		951,400	0	0
LONGVIEW ACQUISITION CORP	COM CL A	543195101	1,243	62,796	SH		SOLE		62,796	0	0
LYRA THERAPEUTICS INC	COM	55234L105	9,295	815,364	SH		SOLE		815,364	0	0
MADRIGAL PHARMACEUTICALS INC	COM	558868105	2,630	23,654	SH		SOLE		23,654	0	0
MEREO BIOPHARMA GROUP PLC	ADS	589492107	416	1,146,308	SH		SOLE		1,146,308	0	0
MERSANA THERAPEUTICS INC	COM	59045L106	2,820	106,000	SH		SOLE		106,000	0	0
MERUS N V	COM	N5749R100	9,411	536,921	SH		SOLE		536,921	0	0
MILESTONE PHARMACEUTICALS IN	COM	59935V107	12,305	1,836,545	SH		SOLE		1,836,545	0	0
MILLENDO THERAPEUTICS INC	COM	60040X103	289	135,193	SH		SOLE		135,193	0	0
MIRATI THERAPEUTICS INC	COM	60468T105	10,981	50,000	SH	Call	SOLE		50,000	0	0
MIRATI THERAPEUTICS INC	COM	60468T105	781	3,557	SH		SOLE		3,557	0	0
MODERNA INC	COM	60770K107	151,482	1,450,000	SH	Put	SOLE		1,450,000	0	0
MODERNA INC	COM	60770K107	6,483	62,059	SH		SOLE		62,059	0	0
MORPHIC HLDG INC	COM	61775R105	17,338	516,763	SH		SOLE		516,763	0	0
MUSTANG BIO INC	COM	62818Q104	1,991	526,003	SH		SOLE		526,003	0	0
NEKTAR THERAPEUTICS	COM	640268108	2,550	150,000	SH	Call	SOLE		150,000	0	0
NEUROCRINE BIOSCIENCES INC	COM	64125C109	2,272	23,700	SH	Call	SOLE		23,700	0	0
NEXTCURE INC	COM	65343E108	2,179	200,000	SH		SOLE		200,000	0	0
NOVAVAX INC	COM NEW	670002401	294	2,636	SH		SOLE		2,636	0	0
NOVAVAX INC	COM NEW	670002401	36,097	323,700	SH	Put	SOLE		323,700	0	0
OCULAR THERAPEUTIX INC	COM	67576A100	14,171	684,573	SH		SOLE		684,573	0	0
OCULAR THERAPEUTIX INC	COM	67576A100	6,461	312,100	SH	Call	SOLE		312,100	0	0
ONCTERNAL THERAPEUTICS INC	COM	68236P107	5,048	1,030,323	SH		SOLE		1,030,323	0	0
OTONOMY INC	COM	68906L105	1,678	259,337	SH		SOLE		259,337	0	0
PANACEA ACQUISITION CORP	CL A	698102100	2,361	201,808	SH		SOLE		201,808	0	0
PASSAGE BIO INC	COM	702712100	3,495	136,697	SH		SOLE		136,697	0	0
PHATHOM PHARMACEUTICALS INC	COM	71722W107	3,321	100,000	SH		SOLE		100,000	0	0
POSEIDA THERAPEUTICS INC	COM	73730P108	2,752	250,837	SH		SOLE		250,837	0	0
PRAXIS PRECISION MEDICINES I	COM	74006W108	275	5,000	SH		SOLE		5,000	0	0
PROTARA THERAPEUTICS INC	COM STK	74365U107	15,725	649,542	SH		SOLE		649,542	0	0
PROTHENA CORP PLC	SHS	G72800108	14,252	1,186,700	SH		SOLE		1,186,700	0	0
PUMA BIOTECHNOLOGY INC	COM	74587V107	563	54,901	SH		SOLE		54,901	0	0
PUMA BIOTECHNOLOGY INC	COM	74587V107	1,026	100,000	SH	Call	SOLE		100,000	0	0
QUIDEL CORP	COM	74838J101	4,545	25,300	SH	Call	SOLE		25,300	0	0
RAPT THERAPEUTICS INC	COM	75382E109	69	3,500	SH	Call	SOLE		3,500	0	0
RAPT THERAPEUTICS INC	COM	75382E109	309	15,600	SH	Put	SOLE		15,600	0	0
REATA PHARMACEUTICALS INC	CL A	75615P103	20,596	166,600	SH	Put	SOLE		166,600	0	0
RIGEL PHARMACEUTICALS INC	COM NEW	766559603	1,209	345,529	SH		SOLE		345,529	0	0
ROCKET PHARMACEUTICALS INC	COM	77313F106	75	1,400	SH		SOLE		1,400	0	0
SAGE THERAPEUTICS INC	COM	78667J108	7,069	81,700	SH	Call	SOLE		81,700	0	0
SAGE THERAPEUTICS INC	COM	78667J108	5,723	66,151	SH		SOLE		66,151	0	0
SAREPTA THERAPEUTICS INC	COM	803607100	148,481	870,900	SH	Put	SOLE		870,900	0	0
SAREPTA THERAPEUTICS INC	COM	803607100	85,416	501,000	SH	Call	SOLE		501,000	0	0
SCHOLAR ROCK HLDG CORP	COM	80706P103	5,680	117,059	SH		SOLE		117,059	0	0
SCPHARMACEUTICALS INC	COM	810648105	7,756	1,466,147	SH		SOLE		1,466,147	0	0
SERES THERAPEUTICS INC	COM	81750R102	8,357	341,100	SH	Call	SOLE		341,100	0	0
SHATTUCK LABS INC	COM	82024L103	3,406	65,000	SH		SOLE		65,000	0	0
SIERRA ONCOLOGY INC	COM NEW	82640U404	5,111	318,890	SH		SOLE		318,890	0	0
SOCIAL CAP HEDSPIA HLDG CO I	COM CL A	G8251K107	1,677	100,000	SH		SOLE		100,000	0	0
SOCIAL CAP HEDSPIA HLDG CO I	COM CL A	G8251K107	2,516	150,000	SH	Call	SOLE		150,000	0	0
SOLENO THERAPEUTICS INC	COM NEW	834203200	236	122,462	SH		SOLE		122,462	0	0
SOLID BIOSCIENCES INC	COM	83422E105	5,973	788,008	SH		SOLE		788,008	0	0
SPDR S&P 500 ETF TR	TR UNIT	78462F103	89,731	240,000	SH	Put	SOLE		240,000	0	0
SPDR SER TR	S&P BIOTECH	78464A870	127,843	908,100	SH	Put	SOLE		908,100	0	0
SPDR SER TR	S&P BIOTECH	78464A870	9,855	70,000	SH	Call	SOLE		70,000	0	0
STEALTH BIOTHERAPEUTICS CORP	SPONSORED ADS	85789A105	57	37,597	SH		SOLE		37,597	0	0
STRONGBRIDGE BIOPHARMA PLC	SHS USD	G85347105	5,929	2,440,028	SH		SOLE		2,440,028	0	0
SUNESIS PHARMACEUTICALS INC	COM NEW	867328874	398	200,000	SH		SOLE		200,000	0	0
SUTRO BIOPHARMA INC	COM	869367102	13,360	615,360	SH		SOLE		615,360	0	0
SYNDAX PHARMACEUTICALS INC	COM	87164F105	2,224	100,000	SH	Call	SOLE		100,000	0	0
SYNDAX PHARMACEUTICALS INC	COM	87164F105	3,134	140,913	SH		SOLE		140,913	0	0
SYROS PHARMACEUTICALS INC	COM	87184Q107	1,085	100,000	SH		SOLE		100,000	0	0
TCR2 THERAPEUTICS INC	COM	87808K106	3,757	121,486	SH		SOLE		121,486	0	0
TG THERAPEUTICS INC	COM	88322Q108	5,202	100,000	SH	Put	SOLE		100,000	0	0
TRACON PHARMACEUTICALS INC	COM NEW	89237H209	31,787	2,716,840	SH		SOLE		2,716,840	0	0
TRANSLATE BIO INC	COM	89374L104	67	3,600	SH	Put	SOLE		3,600	0	0
TRICIDA INC	COM	89610F101	6,055	858,908	SH		SOLE		858,908	0	0
TRILLIUM THERAPEUTICS INC	COM NEW	89620X506	2,942	200,000	SH	Call	SOLE		200,000	0	0
UNITED THERAPEUTICS CORP DEL	COM	91307C102	10,520	69,300	SH	Call	SOLE		69,300	0	0
VAXCYTE INC	COM	92243G108	7,336	276,110	SH		SOLE		276,110	0	0
VERASTEM INC	COM	92337C104	4,802	2,254,591	SH		SOLE		2,254,591	0	0
VINCERA PHARMA INC	COM	92731L106	11,265	538,684	SH		SOLE		538,684	0	0
VIR BIOTECHNOLOGY INC	COM	92764N102	7,176	268,000	SH	Put	SOLE		268,000	0	0
VISTAGEN THERAPEUTICS INC	COM NEW	92840H202	8,703	4,485,952	SH		SOLE		4,485,952	0	0
X4 PHARMACEUTICALS INC	COM	98420X103	5,314	826,424	SH		SOLE		826,424	0	0
XENON PHARMACEUTICALS INC	COM	98420N105	3,432	223,173	SH		SOLE		223,173	0	0
YUMANITY THERAPEUTICS INC	COM	98872L102	2,253	132,514	SH		SOLE		132,514	0	0
ZOGENIX INC	COM NEW	98978L204	3,480	174,091	SH		SOLE		174,091	0	0
ZOGENIX INC	COM NEW	98978L204	17,342	867,400	SH	Call	SOLE		867,400	0	0
ZYMEWORKS INC	COM	98985W102	27,422	580,200	SH	Put	SOLE		580,200	0	0
ZYMEWORKS INC	COM	98985W102	17,732	375,200	SH	Call	SOLE		375,200	0	0
ZYMEWORKS INC	COM	98985W102	73	1,556	SH		SOLE		1,556	0	0