Aprea Therapeutics (APRE) 10-Q 10 Aug 23 2023 Q2 Quarterly report Financial data

Document and Entity Information

Document and Entity Information - shares	6 Months Ended
	Jun. 30, 2023	Aug. 10, 2023
Document and Entity Information
Document Type	10-Q
Document Quarterly Report	true
Document Period End Date	Jun. 30, 2023
Document Transition Report	false
Entity File Number	001-39069
Entity Registrant Name	Aprea Therapeutics, Inc.
Entity Incorporation, State or Country Code	DE
Entity Tax Identification Number	84-2246769
Entity Address, Address Line One	3805 Old Easton Road
Entity Address, City or Town	Doylestown
Entity Address, State or Province	PA
Entity Address, Postal Zip Code	18902
City Area Code	617
Local Phone Number	463-9385
Title of 12(b) Security	Common stock, par value $0.001 per share
Trading Symbol	APRE
Security Exchange Name	NASDAQ
Entity Current Reporting Status	Yes
Entity Interactive Data Current	Yes
Entity Filer Category	Non-accelerated Filer
Entity Small Business	true
Entity Emerging Growth Company	true
Entity Ex Transition Period	true
Entity Shell Company	false
Entity Common Stock, Shares Outstanding		3,736,673
Entity Central Index Key	0001781983
Current Fiscal Year End Date	--12-31
Document Fiscal Year Focus	2023
Document Fiscal Period Focus	Q2
Amendment Flag	false

Condensed Consolidated Balance

Condensed Consolidated Balance Sheets - USD ($)	Jun. 30, 2023	Dec. 31, 2022
Current assets:
Cash and cash equivalents	$ 27,685,131	$ 28,786,647
Prepaid expenses and other current assets	953,670	1,366,859
Total current assets	28,638,801	30,153,506
Property and equipment, net	1,687	2,321
Restricted cash	40,180
Total assets	28,680,668	30,155,827
Current liabilities:
Accounts payable	1,131,197	842,754
Accrued expenses	2,819,624	2,358,332
Total current liabilities	3,950,821	3,201,086
Total liabilities	3,950,821	3,201,086
Commitments and contingencies (Note 8)
Stockholders' equity:
Common stock, $0.001 par value, 400,000,000 shares authorized, 3,731,571 and 2,655,269 shares issued and outstanding at June 30, 2023 and December 31, 2022, respectively.	3,731	2,655
Additional paid-in capital	335,485,317	330,060,836
Accumulated other comprehensive loss	(10,634,872)	(10,623,408)
Accumulated deficit	(301,435,392)	(293,796,405)
Total stockholders' equity	23,418,784	25,643,678
Total liabilities and stockholders' equity	28,680,668	30,155,827
Series A Convertible Preferred Stock
Convertible preferred stock:
Series A convertible preferred stock, $0.001 par value, 40,000,000 shares authorized; 56,227 shares issued and outstanding at June 30, 2023 and December 31, 2022, respectively.	$ 1,311,063	$ 1,311,063

Condensed Consolidated Balanc_2

Condensed Consolidated Balance Sheets (Parenthetical) - $ / shares	Jun. 30, 2023	Dec. 31, 2022
Common stock, par value (in dollars per share)	$ 0.001	$ 0.001
Common stock, shares authorized	400,000,000	400,000,000
Common stock, shares issued	3,731,571	2,655,269
Common stock, shares outstanding	3,731,571	2,655,269
Series A Convertible Preferred Stock
Convertible preferred stock, par value (in dollars per share)	$ 0.001	$ 0.001
Convertible preferred stock, shares authorized	40,000,000	40,000,000
Convertible preferred stock, shares issued	56,227	56,227
Convertible preferred stock, shares outstanding	56,227	56,227

Condensed Consolidated Statemen

Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($)	3 Months Ended		6 Months Ended
	Jun. 30, 2023	Jun. 30, 2022	Jun. 30, 2023	Jun. 30, 2022
Condensed Consolidated Statements of Operations and Comprehensive Loss
Grant revenue	$ 249,688		$ 249,688
Operating expenses:
Research and development	2,202,657	$ 6,811,609	3,459,199	$ 10,901,186
General and administrative	1,698,712	15,633,738	5,064,673	19,619,036
Acquired in-process research and development		76,020,184		76,020,184
Total operating expenses	3,901,369	98,465,531	8,523,872	106,540,406
Loss from operations	(3,651,681)	(98,465,531)	(8,274,184)	(106,540,406)
Other income:
Interest income, net	336,221	52,491	592,631	54,462
Foreign currency gain	56,363	154,566	42,566	290,777
Total other income	392,584	207,057	635,197	345,239
Net loss	(3,259,097)	(98,258,474)	(7,638,987)	(106,195,167)
Other comprehensive loss:
Foreign currency translation	(73,420)	157,655	(11,464)	92,150
Total comprehensive loss	$ (3,332,517)	$ (98,100,819)	$ (7,650,451)	$ (106,103,017)
Net loss per share attributable to common stockholders, basic (in dollars per share)	$ (0.87)	$ (86.72)	$ (2.18)	$ (95.31)
Net loss per share attributable to common stockholders, diluted (in dollars per share)	$ (0.87)	$ (86.72)	$ (2.18)	$ (95.31)
Weighted-average common shares outstanding, basic (in shares)	3,731,571	1,133,092	3,497,329	1,114,189
Weighted-average common shares outstanding, diluted (in shares)	3,731,571	1,133,092	3,497,329	1,114,189

Condensed Consolidated Statem_2

Condensed Consolidated Statements of Convertible Preferred Stock and Stockholders' Equity - USD ($)	Series A Convertible Preferred Stock Preferred Stock	Series A Convertible Preferred Stock	Common Stock ATM offering	Common Stock	Additional Paid-in capital ATM offering	Additional Paid-in capital	Accumulated other comprehensive loss	Accumulated deficit	ATM offering	Total
Equity, beginning balance at Dec. 31, 2021				$ 1,092		$ 240,999,206	$ (10,358,956)	$ (181,134,378)		$ 49,506,964
Equity, beginning balance (in shares) at Dec. 31, 2021				1,092,967
Increase (Decrease) in Stockholders' Equity
Vesting of restricted stock units				$ 6		(6)
Vesting of restricted stock units (in shares)				5,744
Stock-based compensation						2,084,060				2,084,060
Foreign currency translation							(65,505)			(65,505)
Net loss								(7,936,693)		(7,936,693)
Equity, ending balance at Mar. 31, 2022				$ 1,098		243,083,260	(10,424,461)	(189,071,071)		43,588,826
Equity, ending balance (in shares) at Mar. 31, 2022				1,098,711
Equity, beginning balance at Dec. 31, 2021				$ 1,092		240,999,206	(10,358,956)	(181,134,378)		49,506,964
Equity, beginning balance (in shares) at Dec. 31, 2021				1,092,967
Increase (Decrease) in Stockholders' Equity
Issuance of common stock, net (in shares)									0
Foreign currency translation										92,150
Net loss										(106,195,167)
Equity, ending balance at Jun. 30, 2022	$ 68,777,468			$ 1,170		261,817,352	(10,266,806)	(287,329,545)		(35,777,829)
Equity, ending balance (in shares) at Jun. 30, 2022	2,949,630			1,170,087
Equity, beginning balance at Mar. 31, 2022				$ 1,098		243,083,260	(10,424,461)	(189,071,071)		43,588,826
Equity, beginning balance (in shares) at Mar. 31, 2022				1,098,711
Increase (Decrease) in Stockholders' Equity
Issuance of common stock, net (in shares)									0
Issuance of preferred stock upon acquisition of Atrin	$ 68,777,468
Issuance of preferred stock upon acquisition of Atrin (in shares)	2,949,630
Issuance of stock upon acquisition of Atrin				$ 56		1,329,643				1,329,699
Issuance of common stock upon acquisition of Atrin (in shares)				55,869
Value of assumed stock options						2,602,850				2,602,850
Vesting of restricted stock units				$ 16		(16)
Vesting of restricted stock units (in shares)				15,507
Stock-based compensation						14,801,615				14,801,615
Foreign currency translation							157,655			157,655
Net loss								(98,258,474)		(98,258,474)
Equity, ending balance at Jun. 30, 2022	$ 68,777,468			$ 1,170		261,817,352	(10,266,806)	(287,329,545)		(35,777,829)
Equity, ending balance (in shares) at Jun. 30, 2022	2,949,630			1,170,087
Temporary equity, beginning balance (in shares) at Dec. 31, 2022	56,227	56,227
Temporary equity, beginning balance at Dec. 31, 2022	$ 1,311,063	$ 1,311,063
Temporary equity, ending balance (in shares) at Mar. 31, 2023	56,227
Temporary equity, ending balance at Mar. 31, 2023	$ 1,311,063
Equity, beginning balance at Dec. 31, 2022				$ 2,655		330,060,836	(10,623,408)	(293,796,405)		25,643,678
Equity, beginning balance (in shares) at Dec. 31, 2022				2,655,269
Increase (Decrease) in Stockholders' Equity
Issuance of common stock, net			$ 26	$ 1,050	$ 268,099	4,870,815			$ 268,125	4,871,865
Issuance of common stock, net (in shares)			26,302	1,050,000
Stock-based compensation						16,244				16,244
Foreign currency translation							61,956			61,956
Net loss								(4,379,890)		(4,379,890)
Equity, ending balance at Mar. 31, 2023				$ 3,731		335,215,994	(10,561,452)	(298,176,295)		26,481,978
Equity, ending balance (in shares) at Mar. 31, 2023				3,731,571
Temporary equity, beginning balance (in shares) at Dec. 31, 2022	56,227	56,227
Temporary equity, beginning balance at Dec. 31, 2022	$ 1,311,063	$ 1,311,063
Temporary equity, ending balance (in shares) at Jun. 30, 2023	56,227	56,227
Temporary equity, ending balance at Jun. 30, 2023	$ 1,311,063	$ 1,311,063
Equity, beginning balance at Dec. 31, 2022				$ 2,655		330,060,836	(10,623,408)	(293,796,405)		25,643,678
Equity, beginning balance (in shares) at Dec. 31, 2022				2,655,269
Increase (Decrease) in Stockholders' Equity
Issuance of common stock, net (in shares)									26,302
Foreign currency translation										(11,464)
Net loss										(7,638,987)
Equity, ending balance at Jun. 30, 2023				$ 3,731		335,485,317	(10,634,872)	(301,435,392)		23,418,784
Equity, ending balance (in shares) at Jun. 30, 2023				3,731,571
Temporary equity, beginning balance (in shares) at Mar. 31, 2023	56,227
Temporary equity, beginning balance at Mar. 31, 2023	$ 1,311,063
Temporary equity, ending balance (in shares) at Jun. 30, 2023	56,227	56,227
Temporary equity, ending balance at Jun. 30, 2023	$ 1,311,063	$ 1,311,063
Equity, beginning balance at Mar. 31, 2023				$ 3,731		335,215,994	(10,561,452)	(298,176,295)		26,481,978
Equity, beginning balance (in shares) at Mar. 31, 2023				3,731,571
Increase (Decrease) in Stockholders' Equity
Stock-based compensation						269,323				269,323
Foreign currency translation							(73,420)			(73,420)
Net loss								(3,259,097)		(3,259,097)
Equity, ending balance at Jun. 30, 2023				$ 3,731		$ 335,485,317	$ (10,634,872)	$ (301,435,392)		$ 23,418,784
Equity, ending balance (in shares) at Jun. 30, 2023				3,731,571

Condensed Consolidated Statem_3

Condensed Consolidated Statements of Cash Flows - USD ($)	3 Months Ended		6 Months Ended
	Jun. 30, 2023	Jun. 30, 2022	Jun. 30, 2023	Jun. 30, 2022
Cash flows from operating activities:
Net loss			$ (7,638,987)	$ (106,195,167)
Adjustments to reconcile net loss to net cash used in operating activities:
Acquired in-process research and development				72,523,293
Depreciation and amortization			634	6,666
Stockbased compensation			285,567	16,885,675
Amortization of right of use lease asset				120,795
Foreign currency gain	$ (56,363)	$ (154,566)	(42,566)	(290,777)
Changes in operating assets and liabilities:
Prepaid expenses and other current assets			410,246	2,126,847
Accounts payable			289,605	2,288,527
Accrued expenses and other liabilities			499,516	(1,756,495)
Lease liability				(107,306)
Net cash used in operating activities			(6,195,985)	(14,397,942)
Cash flows from financing activities:
Proceeds from issuance of common stock			5,788,918
Common stock issuance costs			(648,928)
Net cash provided by financing activities			5,139,990
Change in cash and cash equivalents			(1,055,995)	(14,397,942)
Effect of exchange rate changes on cash			(5,341)	384,305
Cash and cash equivalents-beginning of year			28,786,647	53,076,052
Cash and cash equivalents-end of period	27,725,311	39,062,415	27,725,311	39,062,415
Reconciliation of cash, cash equivalents and restricted cash
Cash and cash equivalents	27,685,131	39,062,415	27,685,131	39,062,415
Restricted cash	40,180		40,180
Total cash, cash equivalents and restricted cash	$ 27,725,311	$ 39,062,415	$ 27,725,311	39,062,415
Non-cash investing and financing activities:
Operating lease liabilities arising from obtaining right-of-use assets				123,786
Issuance of convertible preferred stock and common stock in connection with acquisition				$ 70,107,167

Nature of business and basis of

Nature of business and basis of presentation	6 Months Ended
	Jun. 30, 2023
Nature of business and basis of presentation
Nature of business and basis of presentation	1. Nature of business and basis of presentation Nature of business —Aprea Therapeutics, Inc. (the “Company”) is a clinical-stage biopharmaceutical company focused on precision oncology through synthetic lethality. The Company began principal operations in 2006 and is headquartered in Doylestown, Pennsylvania. Prior to the acquisition of Atrin Pharmaceuticals Inc. (“Atrin”), the Company was engaged in the clinical development of cancer therapeutics that reactivate the mutant p53 tumor suppressor protein. In December 2020, the Company announced that its pivotal Phase 3 myelodysplastic syndromes trial failed to meet its predefined primary endpoint of complete remission (CR) rate. Given these results, FDA feedback and the costs of continuing the APR-246 development program, the Company shifted focus of its activities to the assets acquired in the May 16, 2022 acquisition of Atrin (see Note 3). The Company’s lead product candidate, which was acquired in the Atrin acquisition, is ATRN-119, a Phase 1-ready small molecule ATR inhibitor being developed for solid tumor indications. Agreement and plan of merger Series A Preferred Stock ​ Reverse stock split twenty Basis of presentation and management plans Since its inception, the Company has devoted substantially all of its efforts to business planning, research and development, recruiting management and technical staff, and raising capital, and has financed its operations through the issuance of convertible preferred stock and common stock. The Company is subject to risks common to companies in the biopharmaceutical industry. There can be no assurance that the Company’s research and development will be successfully completed, that adequate protection for the Company’s intellectual property will be maintained, that any therapeutic products developed will obtain required regulatory approval or that any approved or consumer products will be commercially viable. Even if the Company’s development efforts are successful, it is uncertain when, if ever, the Company will generate significant product sales. The Company believes that the June 30, 2023 cash balance of approximately $27.7 million will be sufficient to fund the Company’s operations into the fourth quarter of 2024. In the event that additional funds are not available thereafter, management would expect to significantly reduce expenditures to conserve cash, which would involve scaling back or curtailing new development activity.

Summary of significant accounti

Summary of significant accounting policies	6 Months Ended
	Jun. 30, 2023
Summary of significant accounting policies
Summary of significant accounting policies	2. Summary of significant accounting policies The Company's complete listing of significant accounting policies are described in Note 2 to the Company's audited consolidated financial statements as of December 31, 2022 included in its annual report on Form 10-K filed with the Securities and Exchange Commission (the “SEC”). Principles of consolidation Unaudited interim consolidated financial statements The unaudited interim consolidated financial statements have been prepared on the same basis as the audited consolidated financial statements, and in management’s opinion, include all adjustments, consisting of only normal recurring adjustments, necessary for the fair presentation of the financial information for the interim periods have been made. The results of operations for the three and six months ended June 30, 2023 are not necessarily indicative of the results to be expected for the full fiscal year or any future period. Use of estimates Foreign currency and currency translation Cash and cash equivalents— Restricted cash— Fair value of financial instruments price that would be received upon sale of an asset or paid to transfer a liability between market participants at measurement dates. ASC Topic 820, Fair Value Measurement (“ASC 820”), establishes a three-level valuation hierarchy for instruments measured at fair value. The hierarchy is based on the transparency of inputs to the valuation of an asset or liability as of the measurement date. The hierarchy defines three levels of valuation inputs, of which the first two are considered observable and the last is considered unobservable: ● Level 1 inputs: Quoted prices in active markets for identical assets or liabilities. ● Level 2 inputs: Inputs other than quoted prices included within Level 1 that are either directly or indirectly observable, such as quoted market prices, interest rates and yield curves. ● Level 3 inputs: Unobservable inputs developed using estimates or assumptions developed by the Company, which reflect those that a market participant would use in pricing the asset or liability. To the extent that the valuation is based on models or inputs that are less observable or unobservable in the market, the determination of fair value requires more judgment. Accordingly, the degree of judgment exercised by the Company in determining fair value is greatest for instruments categorized in Level 3. A financial instrument’s level within the fair value hierarchy is based on the lowest level of any input that is significant to the fair value measurement. The Company’s financial instruments consist of cash and cash equivalents and accounts payable. The carrying amount of accounts payable is considered a reasonable estimate of fair value due to the short-term maturity. Series A Convertible Preferred Stock Accounting for leases At the inception of an arrangement, the Company determines whether the arrangement is or contains a lease based on specific facts and circumstances, the existence of an identified asset(s), if any, and the Company’s control over the use of the identified asset(s), if applicable. Operating lease liabilities and their corresponding right-of-use assets are recorded based on the present value of future lease payments over the expected lease term. The interest rate implicit in lease contracts is typically not readily determinable. As such, the Company utilizes the incremental borrowing rate, which is the rate incurred to borrow on a collateralized basis over a similar term an amount equal to the lease payments in a similar economic environment. The Company has elected not to separate lease and non-lease components as a single component. Operating leases are recognized on the balance sheet as ROU lease assets, lease liabilities current and lease liabilities non-current. Fixed rents are included in the calculation of the lease balances while variable costs paid for certain operating and pass-through costs are excluded. Lease expense is recognized over the expected term on a straight-line basis. Revenue recognition - , definition of a customer. Expenses for grants are tracked by using a project code specific to the grant, and the employees also track hours worked by using the project code. ​ Stock-based compensation For stock-based awards granted to non-employees, compensation expense is recognized over the period during which services are rendered by such non-employees until completed in accordance with the FASB issued ASU No. 2018-07, Compensation Stock Compensation (Topic 718): Improvements to Nonemployee Share Based Payment Accounting. The Company estimates the fair value of each stock option grant on the date of grant using the Black Scholes option pricing model, which uses as inputs the fair value of the Company’s common stock and assumptions the Company makes for the volatility of its common stock, the expected term of its stock options, the risk-free interest rate for a period that approximates the expected term of its stock options and its expected dividend yield. The Company elects to account for forfeitures when they occur. The Company also awards restricted stock units (“RSUs”) to employees and directors. RSUs are generally subject to forfeiture if employment terminates prior to the completion of the vesting restrictions. The Company expenses the cost of the RSUs, which is determined to be the fair market value of the shares of common stock underlying the RSUs at the date of grant, ratably over the period during which the vesting restrictions lapse. Net loss per share The following table sets forth the potentially dilutive securities that have been excluded from the calculation of diluted net loss per share because to include them would be anti-dilutive (in common stock equivalent shares): ​ ​ ​ ​ ​ ​ ​ Six months ended June 30, ​ 2023 2022 Convertible preferred stock (as converted) ​ 28,112 ​ 147,481 Options to purchase common stock 558,141 447,767 Unvested restricted stock units ​ 25,972 ​ — Total shares of common stock equivalents 612,225 595,248 ​ Acquired in-process research and development— The Company measures and recognizes asset acquisitions that are not deemed to be business combinations based on the cost to acquire the assets, including transaction costs. In an asset acquisition, the cost allocated to acquire in-process research and development (“IPR&D) with no alternative future use is charged to expense at the acquisition date. Please see Note 3 – “Acquisition of Atrin” for additional information. Recently issued accounting pronouncements— From time to time, new accounting pronouncements are issued by the Financial Accounting Standards Board (“FASB”) or other standard setting bodies that the Company adopts as of the specified effective date. Management does not believe that any recently issued, but not yet effective accounting pronouncements, if adopted, would have a material impact on the accompanying financial statements.

Acquisition of Atrin

Acquisition of Atrin	6 Months Ended
	Jun. 30, 2023
Acquisition of Atrin
Acquisition of Atrin	3. Acquisition of Atrin ​ On May 16, 2022, the Company completed its acquisition of Atrin in accordance with the terms of the Merger Agreement as described in Note 1 – “Nature of business and basis of presentation”. Under the terms of the Merger Agreement, the Company issued 55,869 shares of common stock and 2,949,630 shares of Series A Preferred Stock. Each share of Series A Preferred Stock is convertible into 10 shares of Common Stock. Over a majority of the Series A Preferred Stockholders elected to convert their Series A Preferred Stock into common stock during the second half of 2022 (see Note 6). ​ The Company concluded that the Atrin Acquisition was not the acquisition of a business, as substantially all of the fair value of the non-monetary assets acquired was concentrated in a single identifiable asset, ATRN-119. ​ The Company determined that the cost to acquire the Atrin assets was $76.2 million, based on the fair value of the equity consideration issued and including direct costs of the acquisition of $3.5 million. The net assets acquired in connection with the Atrin Acquisition were recorded at their estimated fair values as of May 16, 2022, which is the date the Atrin acquisition was completed. The following table summarizes the net assets acquired based on their estimated fair values as of May 16, 2022: ​ ​ ​ ​ ​ Acquired IPR&D ​ $ 76,020,184 Cash and cash equivalents ​ ​ 2,489,745 Prepaid expenses and other assets ​ ​ 34,579 Accounts payable and accrued liabilities ​ ​ (2,336,462) Total Acquisition Value ​ $ 76,208,046 ​ The Atrin Acquisition was accounted for as an asset acquisition as Atrin was not considered to be a business under ASC 805 or SEC Rule 11-01(d). In the estimation of fair value of the asset purchase consideration, the Company used the carrying value of the cash and cash equivalents, prepaid expenses, accounts payable, and accrued liabilities as the most reliable indicator of fair value based on the associated short-term nature of the balances. The remaining fair value was attributable to the acquired IPR&D. Since Atrin was in preclinical development and no clinical trials had commenced at the time of the acquisition, the cost attributable to the IPR&D was expensed in the Company’s consolidated statements of operations and comprehensive loss for the year ended December 31, 2022, as the acquired IPR&D had no alternative future use, as determined by the Company in accordance with U.S. GAAP. ​ As a result of the Atrin Acquisition, the Company announced in May 2022 it was closing its research facility in Sweden and reducing its related workforce in Sweden. The closure of the Swedish research facility and the reduction in workforce resulted in total expenses for employee severance and employee benefits of approximately $1.1 million, of which was recorded as of May 16, 2022. As of June 30, 2023, the remaining liability is approximately $0.1 million. ​ In connection with the Atrin Acquisition, a non-transferable contingent value right (a “CVR”) was distributed to the Aprea stockholders of record as of the close of business on May 13, 2022. Holders of the CVR will be entitled to receive certain stock and/or cash payments from proceeds received by the Company, if any, related to the disposition of its legacy assets in the 2-year period following the closing of the transaction. The CVR had a de minimis value as of May 16, 2022, December 31, 2022 and June 30, 2023.

Leases

Leases	6 Months Ended
	Jun. 30, 2023
Leases
Leases	4. Leases The Company is party to operating leases for office and laboratory space. The Company’s finance leases are immaterial both individually and in the aggregate. The Company has elected to apply the short-term lease exception to all leases of one year or less. Rent expense for the three months ended June 30, 2023 and 2022 was $19,997 and $84,900, respectively. Rent expense for the six months ended June 30, 2023 and 2022 was $39,995 and $159,716, respectively. Rent expense for the three and six months ended June 30, 2023 is a short-term lease cost since the lease has a term of 12 months or less. The Company has an operating lease for office and laboratory space in Doylestown, Pennsylvania which is currently set to expire on December 31, 2023. Rent expense under this lease is $101,000 annually and the company has applied the short-term exception to this lease. The Company had an operating lease in Boston, Massachusetts for office space which expired on December 31, 2022. The Company also had an operating lease for office and laboratory space in Solna, Sweden which was terminated effective November 30, 2022. The Company has no lease obligations beyond 2023. Quantitative information regarding the Company’s leases for the three and six months ended June 30, 2023 and 2022 is as follows: ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Three months ended June 30, ​ Six months ended June 30, Lease Cost 2023 2022 ​ 2023 2022 ​ Operating lease cost ​ $ — ​ $ 60,679 ​ $ — ​ $ 120,795 ​ Other Information ​ ​ ​ ​ ​ ​ ​ ​ ​ Operating cash flows paid for amounts included in the measurement of lease liabilities ​ $ — ​ $ 64,057 ​ $ — ​ $ 128,113 ​ Operating lease liabilities arising from obtaining right‑of‑use assets ​ $ — ​ $ — ​ $ — ​ $ 123,786 ​ Weighted average remaining lease term (years) ​ ​ — ​ ​ 0.50-1.00 ​ — ​ 0.50-1.00 ​ Weighted average discount rate ​ ​ — ​ ​ 3.0 - 4.3% ​ ​ — ​ 3.0 - 4.3% ​ ​ ​ ​ As most of the Company’s leases do not provide an implicit rate, the Company used its incremental borrowing rate based on the information available at commencement date in determining the present value of lease payments.

Accrued expenses

Accrued expenses	6 Months Ended
	Jun. 30, 2023
Accrued expenses
Accrued expenses	5. Accrued expenses Accrued expenses consist of the following: ​ ​ ​ ​ ​ ​ ​ ​ ​ June 30, December 31, ​ ​ 2023 ​ 2022 Professional fees ​ $ 153,742 ​ $ 75,012 Compensation, severance and benefits ​ 1,275,530 ​ 1,397,977 Research and development ​ 1,256,695 ​ 688,858 Other ​ 133,657 ​ 196,485 Total accrued expenses ​ $ 2,819,624 ​ $ 2,358,332 ​

Stockholders' equity

Stockholders' equity	6 Months Ended
	Jun. 30, 2023
Stockholders' equity
Stockholders' equity	6. Stockholders’ equity The total number of shares of all classes of capital stock that the Company is authorized to issue is 440,000,000 shares, consisting of 400,000,000 shares of common stock, par value $0.001 per share and 40,000,000 shares of preferred stock, par value $0.001 per share. ​ Conversion of Series A Preferred Stock ​ As discussed in Note 1 and Note 3, the Company issued to the shareholders of Atrin 2,949,630 shares of Series A Preferred Stock as partial consideration of the Atrin Acquisition. Each share of Series A Preferred Stock is convertible into 10 shares of common stock on a pre-Reverse Stock Split basis. The Company held a stockholders’ meeting on July 28, 2022 where approval of the conversion of the Series A Preferred Stock into shares of the Company’s common stock in accordance with Nasdaq Listing Rule 5635(a) was received. As of June 30, 2023, a total of 2,893,403 shares of Series A Preferred Stock was converted into 1,446,701 shares of common stock. As of June 30, 2023, a total of 56,227 shares of Series A Preferred Stock remained outstanding. ​ Common Stock The holders of common stock are entitled to one vote for each share of common stock. In the event of any voluntary or involuntary liquidation, dissolution or winding up of the Company, after the payment or provision for payment of all debts and liabilities of the Company, the holders of common stock shall be entitled to share in the remaining assets of the Company available for distribution, if any. Shelf Registration Statement On November 12, 2020, the Company filed a universal shelf registration statement with the SEC for the issuance of common stock, preferred stock, warrants, rights, debt securities and units up to an aggregate of $350.0 million (the “2020 Shelf Registration Statement”). On November 30, 2020, the Shelf Registration Statement was declared effective by the SEC. The universal shelf registration statement includes an at-the-market (“ATM”) offering program and the Company filed a Prospectus Supplement dated September 2, 2022, for the sale of up to $14,744,728 of shares of the Company’s common stock pursuant to its ATM offering program. The Company agreed to pay a commission of 3% of the gross proceeds of any common stock sold in connection with the ATM offering program. The Company is currently subject to General Instruction I.B.6 of Form S-3, as a result of which the amount of funds the Company can raise through primary public offerings of securities in any 12-month period using the 2020 Shelf Registration Statement is limited to one-third of the aggregate market value of the voting and non-voting common equity held by non-affiliates. The Company will remain subject to this one-third limitation until such time as the Company’s public float exceeds $75 million. So long as the aggregate market value of the Company’s common stock held by non-affiliates is less than $75 million, the Company will not sell shares under the ATM (together with any other securities sold pursuant to General Instruction I.B.6 of Form S-3) with a value of more than one-third of the aggregate market value of the Company’s common stock held by non-affiliates in any 12-month period due to the limitations of General Instruction I.B.6 of Form S-3 and the current public float of our common stock. During the six months ended June 30, 2023, the Company issued and sold 26,302 shares of common stock under the ATM offering program resulting in net proceeds to the Company of approximately $0.3 million after deducting approximately $8,000 in issuance costs. The Company did not sell any stock under the ATM offering program during three and six months ended June 30, 2022. In February 2023, the Company issued and sold 1,050,000 shares of common stock at a public offering price of $5.25 per share pursuant to the 2020 Shelf Registration Statement resulting in net proceeds to the Company of approximately $4.9 million, after deducting underwriting discounts and offering expenses of approximately $0.6 million. Stock-Based Compensation Expense The Company recorded stock-based compensation expense of $269,323, and $14.8 million for the three months ended June 30, 2023 and 2022, respectively. The Company recorded stock-based compensation expense of $285,567, and $16.9 million for the six months ended June 30, 2023 and 2022, respectively. ​

Income taxes

Income taxes	6 Months Ended
	Jun. 30, 2023
Income taxes
Income taxes	7. Income Taxes ​ The Company has no income tax expense due to operating losses incurred for the three and six months ended June 30, 2023 and 2022. The Company has provided a valuation allowance for the full amount of the net deferred tax assets as, based on all available evidence, it is considered more likely than not that all the recorded deferred tax assets will not be realized in a future period. Realization of the future tax benefits is dependent on may factors, including the Company’s ability to generate taxable income within the net operating loss carryforward period. Under the provisions of the U.S. Internal Revenue Code and Sweden tax law, certain substantial changes in the Company’s ownership, including a sale of the Company or significant changes in ownership due to sales of equity, may have limited, or may limit in the future, the amount of net operating loss carryforwards that could be used annually to offset future taxable income. For U.S. and Swedish income tax purposes, the Company has not completed a study to assess whether a change of control has occurred or whether there have been changes of control since the Company’s formation due to the complexity and cost associated with such study and because there could be additional changes of control in the future. As a result, the Company is not able to estimate the effect of the change in control, if any, on the Company’s ability to utilize U.S. or Swedish net operating losses or other tax attribute carryforwards in the future. For Swedish income tax purposes, the Company’s net operating losses may be subject to limitations in accordance with the country’s group contribution restriction laws. ​ The Company files tax returns in Sweden, the United States, Massachusetts and Pennsylvania. Income tax returns prior to 2019 in the United States and Massachusetts are no longer subject to examination and income tax returns prior to 2016 are no longer subject to examination in Sweden. The Company is not currently under examination by the IRS or any other jurisdictions for any tax years. As tax law is complex and often subject to varied interpretations, it is uncertain whether some of the Company’s tax positions will be sustained upon examination. Tax liabilities associated with uncertain tax positions represent unrecognized tax benefits, which arise when the estimated benefit recorded in the Company’s financial statements differs from the amounts taken or expected to be taken in a tax return because of the uncertainties described above. Substantially all of these unrecognized tax benefits, if recognized, would benefit the Company’s effective income tax rate. As of June 30, 2023 and December 31, 2022, the Company had approximately $0.1 million of liabilities related to uncertain tax positions. As the Company’s uncertain tax positions can be offset by available net operating losses, the Company did not recognize interest and penalties for 2023 and 2022.

Commitments and contingencies

Commitments and contingencies	6 Months Ended
	Jun. 30, 2023
Commitments and contingencies.
Commitments and contingencies	8. Commitments and contingencies The Company records a provision for contingent losses when it is both probable that a liability has been incurred and the amount of the loss can be reasonably estimated. As of June 30, 2023, the Company has not recorded a provision for any contingent losses.

Subsequent events

Subsequent events	6 Months Ended
	Jun. 30, 2023
Subsequent events
Subsequent events	9. Subsequent events ​ On July 3, 2023, the Company received notification from the Nasdaq Listing Qualifications Department of the Nasdaq Stock Market (the “Nasdaq”) that the Company’s application to transfer the listing of its common stock from the Nasdaq Global Select Market to the Nasdaq Capital Market was approved. The Company’s securities were transferred to the Nasdaq Capital Market at the opening of business on July 6, 2023. ​

Summary of significant accoun_2

Summary of significant accounting policies (Policies)	6 Months Ended
	Jun. 30, 2023
Summary of significant accounting policies
Principles of consolidation	Principles of consolidation
Unaudited interim consolidated financial statements	Unaudited interim consolidated financial statements The unaudited interim consolidated financial statements have been prepared on the same basis as the audited consolidated financial statements, and in management’s opinion, include all adjustments, consisting of only normal recurring adjustments, necessary for the fair presentation of the financial information for the interim periods have been made. The results of operations for the three and six months ended June 30, 2023 are not necessarily indicative of the results to be expected for the full fiscal year or any future period.
Use of estimates	Use of estimates
Foreign currency and currency translation	Foreign currency and currency translation
Cash and cash equivalents and restricted cash	Cash and cash equivalents— Restricted cash—
Fair value of financial instruments	Fair value of financial instruments price that would be received upon sale of an asset or paid to transfer a liability between market participants at measurement dates. ASC Topic 820, Fair Value Measurement (“ASC 820”), establishes a three-level valuation hierarchy for instruments measured at fair value. The hierarchy is based on the transparency of inputs to the valuation of an asset or liability as of the measurement date. The hierarchy defines three levels of valuation inputs, of which the first two are considered observable and the last is considered unobservable: ● Level 1 inputs: Quoted prices in active markets for identical assets or liabilities. ● Level 2 inputs: Inputs other than quoted prices included within Level 1 that are either directly or indirectly observable, such as quoted market prices, interest rates and yield curves. ● Level 3 inputs: Unobservable inputs developed using estimates or assumptions developed by the Company, which reflect those that a market participant would use in pricing the asset or liability. To the extent that the valuation is based on models or inputs that are less observable or unobservable in the market, the determination of fair value requires more judgment. Accordingly, the degree of judgment exercised by the Company in determining fair value is greatest for instruments categorized in Level 3. A financial instrument’s level within the fair value hierarchy is based on the lowest level of any input that is significant to the fair value measurement. The Company’s financial instruments consist of cash and cash equivalents and accounts payable. The carrying amount of accounts payable is considered a reasonable estimate of fair value due to the short-term maturity.
Series A Convertible Preferred Stock	Series A Convertible Preferred Stock
Accounting for leases	Accounting for leases At the inception of an arrangement, the Company determines whether the arrangement is or contains a lease based on specific facts and circumstances, the existence of an identified asset(s), if any, and the Company’s control over the use of the identified asset(s), if applicable. Operating lease liabilities and their corresponding right-of-use assets are recorded based on the present value of future lease payments over the expected lease term. The interest rate implicit in lease contracts is typically not readily determinable. As such, the Company utilizes the incremental borrowing rate, which is the rate incurred to borrow on a collateralized basis over a similar term an amount equal to the lease payments in a similar economic environment. The Company has elected not to separate lease and non-lease components as a single component. Operating leases are recognized on the balance sheet as ROU lease assets, lease liabilities current and lease liabilities non-current. Fixed rents are included in the calculation of the lease balances while variable costs paid for certain operating and pass-through costs are excluded. Lease expense is recognized over the expected term on a straight-line basis.
Revenue recognition	Revenue recognition - , definition of a customer. Expenses for grants are tracked by using a project code specific to the grant, and the employees also track hours worked by using the project code.
Stock-based compensation	Stock-based compensation For stock-based awards granted to non-employees, compensation expense is recognized over the period during which services are rendered by such non-employees until completed in accordance with the FASB issued ASU No. 2018-07, Compensation Stock Compensation (Topic 718): Improvements to Nonemployee Share Based Payment Accounting. The Company estimates the fair value of each stock option grant on the date of grant using the Black Scholes option pricing model, which uses as inputs the fair value of the Company’s common stock and assumptions the Company makes for the volatility of its common stock, the expected term of its stock options, the risk-free interest rate for a period that approximates the expected term of its stock options and its expected dividend yield. The Company elects to account for forfeitures when they occur. The Company also awards restricted stock units (“RSUs”) to employees and directors. RSUs are generally subject to forfeiture if employment terminates prior to the completion of the vesting restrictions. The Company expenses the cost of the RSUs, which is determined to be the fair market value of the shares of common stock underlying the RSUs at the date of grant, ratably over the period during which the vesting restrictions lapse.
Net loss per share	Net loss per share The following table sets forth the potentially dilutive securities that have been excluded from the calculation of diluted net loss per share because to include them would be anti-dilutive (in common stock equivalent shares): ​ ​ ​ ​ ​ ​ ​ Six months ended June 30, ​ 2023 2022 Convertible preferred stock (as converted) ​ 28,112 ​ 147,481 Options to purchase common stock 558,141 447,767 Unvested restricted stock units ​ 25,972 ​ — Total shares of common stock equivalents 612,225 595,248
Acquired in-process research and development	Acquired in-process research and development— The Company measures and recognizes asset acquisitions that are not deemed to be business combinations based on the cost to acquire the assets, including transaction costs. In an asset acquisition, the cost allocated to acquire in-process research and development (“IPR&D) with no alternative future use is charged to expense at the acquisition date. Please see Note 3 – “Acquisition of Atrin” for additional information.
Recently issued accounting pronouncements	Recently issued accounting pronouncements— From time to time, new accounting pronouncements are issued by the Financial Accounting Standards Board (“FASB”) or other standard setting bodies that the Company adopts as of the specified effective date. Management does not believe that any recently issued, but not yet effective accounting pronouncements, if adopted, would have a material impact on the accompanying financial statements.

Summary of significant accoun_3

Summary of significant accounting policies (Tables)	6 Months Ended
	Jun. 30, 2023
Summary of significant accounting policies
Schedule of potentially dilutive securities excluded from calculation of diluted net loss per share	The following table sets forth the potentially dilutive securities that have been excluded from the calculation of diluted net loss per share because to include them would be anti-dilutive (in common stock equivalent shares): ​ ​ ​ ​ ​ ​ ​ Six months ended June 30, ​ 2023 2022 Convertible preferred stock (as converted) ​ 28,112 ​ 147,481 Options to purchase common stock 558,141 447,767 Unvested restricted stock units ​ 25,972 ​ — Total shares of common stock equivalents 612,225 595,248

Acquisition of Atrin (Tables)

Acquisition of Atrin (Tables)	6 Months Ended
	Jun. 30, 2023
Acquisition of Atrin
Schedule of net assets acquired based on the estimated fair values	​ ​ ​ ​ ​ Acquired IPR&D ​ $ 76,020,184 Cash and cash equivalents ​ ​ 2,489,745 Prepaid expenses and other assets ​ ​ 34,579 Accounts payable and accrued liabilities ​ ​ (2,336,462) Total Acquisition Value ​ $ 76,208,046

Leases (Tables)

Leases (Tables)	6 Months Ended
	Jun. 30, 2023
Leases
Summary of quantitative information regarding the Company's leases	​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Three months ended June 30, ​ Six months ended June 30, Lease Cost 2023 2022 ​ 2023 2022 ​ Operating lease cost ​ $ — ​ $ 60,679 ​ $ — ​ $ 120,795 ​ Other Information ​ ​ ​ ​ ​ ​ ​ ​ ​ Operating cash flows paid for amounts included in the measurement of lease liabilities ​ $ — ​ $ 64,057 ​ $ — ​ $ 128,113 ​ Operating lease liabilities arising from obtaining right‑of‑use assets ​ $ — ​ $ — ​ $ — ​ $ 123,786 ​ Weighted average remaining lease term (years) ​ ​ — ​ ​ 0.50-1.00 ​ — ​ 0.50-1.00 ​ Weighted average discount rate ​ ​ — ​ ​ 3.0 - 4.3% ​ ​ — ​ 3.0 - 4.3% ​

Accrued expenses (Tables)

Accrued expenses (Tables)	6 Months Ended
	Jun. 30, 2023
Accrued expenses
Schedule of accrued expenses	​ ​ ​ ​ ​ ​ ​ ​ ​ June 30, December 31, ​ ​ 2023 ​ 2022 Professional fees ​ $ 153,742 ​ $ 75,012 Compensation, severance and benefits ​ 1,275,530 ​ 1,397,977 Research and development ​ 1,256,695 ​ 688,858 Other ​ 133,657 ​ 196,485 Total accrued expenses ​ $ 2,819,624 ​ $ 2,358,332

Nature of business and basis _2

Nature of business and basis of presentation (Details)	Feb. 10, 2023	May 16, 2022 USD ($) $ / shares shares	Jun. 30, 2023 USD ($) $ / shares	Dec. 31, 2022 USD ($) $ / shares	Jun. 30, 2022 USD ($)
Common stock, par value (in dollars per share) | $ / shares			$ 0.001	$ 0.001
Reverse stock split ratio	0.05
Cash balance | $			$ 27,685,131	$ 28,786,647	$ 39,062,415
Atrin Pharmaceuticals, Inc
Cash balance | $		$ 2,489,745
Common Stock | Atrin Pharmaceuticals, Inc
Issuance of stock upon acquisition of Atrin (in shares). | shares		55,869
Common stock, par value (in dollars per share) | $ / shares		$ 0.001
Number of shares to purchase under option | shares		163,757
Series A Convertible Preferred Stock | Atrin Pharmaceuticals, Inc
Issuance of stock upon acquisition of Atrin (in shares). | shares		2,949,630
Conversion value | $		$ 68,800,000
Preferred stock conversion ratio		10

Summary of significant accoun_4

Summary of significant accounting policies - Restricted cash (Details)	Jun. 30, 2023 USD ($)
Summary of significant accounting policies
Restricted cash	$ 40,180

Summary of significant accoun_5

Summary of significant accounting policies - Potentially dilutive securities (Details) - shares	6 Months Ended
	Jun. 30, 2023	Jun. 30, 2022
Potentially dilutive securities
Total shares of common stock equivalents	612,225	595,248
Convertible preferred stock (as converted)
Potentially dilutive securities
Total shares of common stock equivalents	28,112	147,481
Options to purchase common stock
Potentially dilutive securities
Total shares of common stock equivalents	558,141	447,767
Unvested restricted stock units
Potentially dilutive securities
Total shares of common stock equivalents	25,972

Acquisition of Atrin (Details)

Acquisition of Atrin (Details) - Atrin Pharmaceuticals, Inc $ in Millions	May 16, 2022 USD ($) shares
Acquisition of Atrin
Cost to acquire Atrin assets | $	$ 76.2
Direct costs of acquisition of Atrin assets | $	$ 3.5
Common Stock
Acquisition of Atrin
Issuance of stock upon acquisition of Atrin (in shares). | shares	55,869
Series A Convertible Preferred Stock
Acquisition of Atrin
Issuance of stock upon acquisition of Atrin (in shares). | shares	2,949,630
Preferred stock conversion ratio	10

Acquisition of Atrin - Summary

Acquisition of Atrin - Summary of net assets acquired (Details) - USD ($)	Jun. 30, 2023	Dec. 31, 2022	Jun. 30, 2022	May 16, 2022
Acquisition of Atrin
Cash and cash equivalents	$ 27,685,131	$ 28,786,647	$ 39,062,415
Prepaid expenses and other assets	$ 953,670	$ 1,366,859
Atrin Pharmaceuticals, Inc
Acquisition of Atrin
Acquired IPR&D				$ 76,020,184
Cash and cash equivalents				2,489,745
Prepaid expenses and other assets				34,579
Accounts payable and accrued liabilities				(2,336,462)
Total Acquisition Value				$ 76,208,046

Acquisition of Atrin - Addition

Acquisition of Atrin - Additional information (Details) - Atrin Pharmaceuticals, Inc - USD ($) $ in Millions	May 16, 2022	Jun. 30, 2023
Acquisition of Atrin
Employee severance	$ 1.1
Employee severance liability		$ 0.1
Term of contingent value right	2 years

Leases - Summary (Details)

Leases - Summary (Details) - USD ($)	3 Months Ended		6 Months Ended
	Jun. 30, 2023	Jun. 30, 2022	Jun. 30, 2023	Jun. 30, 2022
Leases
Rent expense	$ 19,997	$ 84,900	$ 39,995	$ 159,716
Annual base rent			$ 101,000

Leases - Quantitative Informati

Leases - Quantitative Information (Details)	3 Months Ended	6 Months Ended
	Jun. 30, 2022 USD ($)	Jun. 30, 2022 USD ($)
Quantitative information regarding the Company's leases
Operating lease cost	$ 60,679	$ 120,795
Other Information
Operating cash flows paid for amounts included in the measurement of lease liabilities	$ 64,057	128,113
Operating lease liabilities arising from obtaining right-of-use assets		$ 123,786
Minimum
Other Information
Weighted average remaining lease term (years)	6 months	6 months
Weighted average discount rate	3%	3%
Maximum
Other Information
Weighted average remaining lease term (years)	1 year	1 year
Weighted average discount rate	4.30%	4.30%

Accrued expenses (Details)

Accrued expenses (Details) - USD ($)	Jun. 30, 2023	Dec. 31, 2022
Accrued expenses
Professional fees	$ 153,742	$ 75,012
Compensation, severance and benefits	1,275,530	1,397,977
Research and development	1,256,695	688,858
Other	133,657	196,485
Total accrued expenses	$ 2,819,624	$ 2,358,332

Stockholders' equity (Details)

Stockholders' equity (Details)			1 Months Ended	3 Months Ended		6 Months Ended
	May 16, 2022 $ / shares shares	Nov. 12, 2020 USD ($)	Feb. 28, 2023 USD ($) $ / shares shares	Jun. 30, 2023 USD ($) $ / shares shares	Jun. 30, 2022 USD ($) shares	Jun. 30, 2023 USD ($) Vote $ / shares shares	Jun. 30, 2022 USD ($) shares	Dec. 31, 2022 $ / shares shares
Common stock
Stock, shares authorized				440,000,000		440,000,000
Common stock, shares authorized				400,000,000		400,000,000		400,000,000
Common stock, par value (in dollars per share) | $ / shares				$ 0.001		$ 0.001		$ 0.001
Preferred stock, shares authorized				40,000,000		40,000,000
Preferred stock, par value (in dollars per share) | $ / shares				$ 0.001		$ 0.001
Commission payable as a percentage of gross proceeds from sale of common stock under ATM offering		3%
Number of voting rights per common share | Vote						1
Stock based compensation expense | $				$ 269,323	$ 14,800,000	$ 285,567	$ 16,900,000
Shelf Registration Statement
Maximum amount to be issued under universal shelf registration statement | $		$ 350,000,000
Maximum amount to be issued under at-the-market offering program | $		$ 14,744,728
Proceeds from issuance of common stock | $						5,788,918
Common stock issuance costs | $						$ 648,928
Common Stock
Common stock
Conversion of preferred stock into common stock (in shares)						1,446,701
Shelf Registration Statement
Shares issued			1,050,000
Issue price per share | $ / shares			$ 5.25
Proceeds from issuance of common stock | $			$ 4,900,000
Common stock issuance costs | $			$ 600,000
Series A Convertible Preferred Stock
Common stock
Conversion of preferred stock into common stock (in shares)						2,893,403
Number of shares remained to be converted into common stock				56,227		56,227
Atrin Pharmaceuticals, Inc | Common Stock
Common stock
Common stock, par value (in dollars per share) | $ / shares	$ 0.001
Issuance of stock upon acquisition of Atrin (in shares).	55,869
Atrin Pharmaceuticals, Inc | Series A Convertible Preferred Stock
Common stock
Issuance of stock upon acquisition of Atrin (in shares).	2,949,630
Preferred stock conversion ratio	10
ATM offering
Shelf Registration Statement
Shares issued					0	26,302	0
Proceeds from issuance of common shares | $						$ 300,000
Common stock issuance costs | $						$ 8,000

Income taxes - Narrative (Detai

Income taxes - Narrative (Details) - USD ($) $ in Millions	6 Months Ended
	Jun. 30, 2023	Jun. 30, 2022	Dec. 31, 2022
Income taxes
Income tax expense	$ 0	$ 0
Uncertain tax positions	$ 0.1		$ 0.1

Commitments and contingencies (

Commitments and contingencies (Details)	6 Months Ended
	Jun. 30, 2023 USD ($)
Commitments and contingencies.
Provision for contingent losses	$ 0