Immuneering (IMRX) 10-Q 10 Aug 22 2022 Q2 Quarterly report Financial data

Document and Entity Information

Document and Entity Information - shares	6 Months Ended
	Jun. 30, 2022	Aug. 03, 2022
Document Type	10-Q
Document Quarterly Report	true
Document Transition Report	false
Document Period End Date	Jun. 30, 2022
Entity File Number	001-40675
Entity Registrant Name	Immuneering Corp
Entity Incorporation, State or Country Code	DE
Entity Tax Identification Number	26-1976972
Entity Address, Address Line One	245 Main St
Entity Address, Address Line Two	Second Floor
Entity Address, City or Town	Cambridge
Entity Address State Or Province	MA
Entity Address, Postal Zip Code	02142
City Area Code	617
Local Phone Number	500-8080
Title of 12(b) Security	Class A common Stock, par value $0.001 per share
Trading Symbol	IMRX
Security Exchange Name	NASDAQ
Entity Current Reporting Status	Yes
Entity Interactive Data Current	Yes
Entity Filer Category	Non-accelerated Filer
Entity Small Business	true
Entity Emerging Growth Company	true
Entity Ex Transition Period	false
Entity Shell Company	false
Entity Central Index Key	0001790340
Current Fiscal Year End Date	--12-31
Document Fiscal Year Focus	2022
Document Fiscal Period Focus	Q2
Amendment Flag	false
Class A Common Stock
Entity Common Stock, Shares Outstanding		26,392,299
Class B Common Stock
Entity Common Stock, Shares Outstanding		0

CONDENSED CONSOLIDATED BALANCE

CONDENSED CONSOLIDATED BALANCE SHEETS - USD ($)	Jun. 30, 2022	Dec. 31, 2021
Current assets:
Cash and cash equivalents	$ 87,937,479	$ 74,888,145
Marketable securities, current	40,163,875	74,311,203
Accounts receivable	178,425	246,040
Prepaids and other current assets	890,409	2,888,608
Total current assets	129,170,188	152,333,996
Marketable securities, non-current		996,560
Property and equipment, net	985,007	807,223
Goodwill	6,690,431	6,701,726
Intangible asset	423,580	439,000
Right-of-use assets, net	4,691,157	5,324,198
Other assets	89,579	102,129
Total assets	142,049,942	166,704,832
Current liabilities:
Accounts payable	1,240,241	1,394,340
Accrued expenses	2,226,687	3,965,447
Other liabilities, current	47,213
Lease liabilities, current	286,374	274,039
Total current liabilities	3,800,515	5,633,826
Long-term liabilities:
Other liabilities, non-current	9,898
Lease liabilities, non-current	4,644,683	5,090,897
Total liabilities	8,455,096	10,724,723
Commitments and contingencies (Note 12)
Stockholders' equity:
Additional paid-in capital	217,447,080	215,276,186
Accumulated other comprehensive loss	(181,561)	(49,009)
Accumulated deficit	(83,697,065)	(59,273,388)
Total stockholders' equity	133,594,846	155,980,109
Total liabilities and stockholders' equity	142,049,942	166,704,832
Class A Common Stock
Stockholders' equity:
Common stock	$ 26,392	$ 26,320

CONDENSED CONSOLIDATED BALANC_2

CONDENSED CONSOLIDATED BALANCE SHEETS (Parentheticals) - $ / shares	Jun. 30, 2022	Dec. 31, 2021
Preferred stock, par value per share (in dollars per share)	$ 0.001	$ 0.001
Preferred stock authorized (in shares)	10,000,000	10,000,000
Preferred stock, shares issued (in shares)	0	0
Preferred stock, shares outstanding (in shares)	0	0
Class A Common Stock
Common stock, par value per share (in dollars per share)	$ 0.001	$ 0.001
Common stock, shares authorized (in shares)	200,000,000	200,000,000
Common stock, shares issued (in shares)	26,392,299	26,320,199
Common stock, shares outstanding (in shares)	26,392,299	26,320,199
Class B Common Stock
Common stock, par value per share (in dollars per share)	$ 0.001	$ 0.001
Common stock, shares authorized (in shares)	20,000,000	20,000,000
Common stock, shares issued (in shares)	0	0
Common stock, shares outstanding (in shares)	0	0

CONDENSED CONSOLIDATED STATEMEN

CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($)	3 Months Ended		6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021
CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS
Revenue	$ 94,419	$ 660,040	$ 278,117	$ 1,408,240
Cost of revenue	47,933	318,601	138,778	727,763
Gross profit	46,486	341,439	139,339	680,477
Operating expenses
Research and development	7,981,075	6,991,965	17,031,517	12,382,985
General and administrative	3,704,143	1,340,398	7,664,112	2,524,422
Amortization of intangible asset	7,317		15,420
Total operating expenses	11,692,535	8,332,363	24,711,049	14,907,407
Loss from operations	(11,646,049)	(7,990,924)	(24,571,710)	(14,226,930)
Other income (expense)
Interest income	142,799	3,259	275,304	9,614
Other expense	(24,053)		(127,271)
Net loss	$ (11,527,303)	$ (7,987,665)	$ (24,423,677)	$ (14,217,316)
Net loss per share attributable to common stockholders, basic	$ (0.44)	$ (1.61)	$ (0.93)	$ (2.87)
Net loss per share attributable to common stockholders, diluted	$ (0.44)	$ (1.61)	$ (0.93)	$ (2.87)
Weighted-average common shares outstanding, basic	26,386,343	4,954,553	26,372,787	4,952,352
Weighted-average common shares outstanding, diluted	26,386,343	4,954,553	26,372,787	4,952,352
Other comprehensive loss:
Unrealized losses from marketable securities	$ (14,166)		$ (132,552)
Comprehensive Loss	$ (11,541,469)	$ (7,987,665)	$ (24,556,229)	$ (14,217,316)

CONDENSED CONSOLIDATED STATEM_2

CONDENSED CONSOLIDATED STATEMENTS OF CONVERTIBLE PREFERRED STOCK AND STOCKHOLDERS' EQUITY (DEFICIT) - USD ($)	Preferred Stock Series A Preferred Stock	Preferred Stock Series B Preferred Stock	Preferred Stock	Common Stock Class A Common Stock	Additional Paid-In Capital	Accumulated other comprehensive loss	Accumulated Deficit	Total
Beginning Balance (in shares) at Dec. 31, 2020				4,950,129
Beginning Balance at Dec. 31, 2020				$ 4,950	$ 3,251,240		$ (25,737,640)	$ (22,481,450)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Stock-based compensation expense					182,225			182,225
Net loss							(6,229,651)	(6,229,651)
Ending Balance at Mar. 31, 2021				$ 4,950	3,433,465		(31,967,291)	(28,528,876)
Ending Balance (in shares) at Mar. 31, 2021				4,950,129
Beginning Balance at Dec. 31, 2020	$ 21,119,940	$ 36,983,910	$ 58,103,850
Beginning Balance (in shares) at Dec. 31, 2020	2,495,933	3,619,292
Ending Balance at Mar. 31, 2021	$ 21,119,940	$ 36,983,910	58,103,850
Ending Balance (in shares) at Mar. 31, 2021	2,495,933	3,619,292
Beginning Balance (in shares) at Dec. 31, 2020				4,950,129
Beginning Balance at Dec. 31, 2020				$ 4,950	3,251,240		(25,737,640)	(22,481,450)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Net loss								(14,217,316)
Ending Balance at Jun. 30, 2021				$ 5,276	4,763,900		(39,954,956)	(35,185,780)
Ending Balance (in shares) at Jun. 30, 2021				5,275,936
Beginning Balance at Dec. 31, 2020	$ 21,119,940	$ 36,983,910	58,103,850
Beginning Balance (in shares) at Dec. 31, 2020	2,495,933	3,619,292
Ending Balance at Jun. 30, 2021	$ 21,119,940	$ 61,772,761	82,892,701
Ending Balance (in shares) at Jun. 30, 2021	2,495,933	6,032,145
Beginning Balance (in shares) at Mar. 31, 2021				4,950,129
Beginning Balance at Mar. 31, 2021				$ 4,950	3,433,465		(31,967,291)	(28,528,876)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock upon exercise of stock options				$ 18	52,609			52,627
Issuance of common stock upon exercise of stock options (in shares)				17,499
Issuance of common stock upon exercise of warrants				$ 308	926,817			927,125
Issuance of common stock upon exercise of warrants (in shares)				308,308
Stock-based compensation expense					351,009			351,009
Net loss							(7,987,665)	(7,987,665)
Ending Balance at Jun. 30, 2021				$ 5,276	4,763,900		(39,954,956)	(35,185,780)
Ending Balance (in shares) at Jun. 30, 2021				5,275,936
Beginning Balance at Mar. 31, 2021	$ 21,119,940	$ 36,983,910	58,103,850
Beginning Balance (in shares) at Mar. 31, 2021	2,495,933	3,619,292
Increase (Decrease) in Temporary Equity [Roll Forward]
Issuance of convertible preferred stock, net of issuance costs		$ 24,788,851	24,788,851
Issuance of convertible preferred stock, net of issuance costs (in shares)		2,412,853
Ending Balance at Jun. 30, 2021	$ 21,119,940	$ 61,772,761	$ 82,892,701
Ending Balance (in shares) at Jun. 30, 2021	2,495,933	6,032,145
Beginning Balance (in shares) at Dec. 31, 2021				26,320,199
Beginning Balance at Dec. 31, 2021				$ 26,320	215,276,186	$ (49,009)	(59,273,388)	155,980,109
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock upon exercise of stock options				$ 63	193,048			193,111
Issuance of common stock upon exercise of stock options (in shares)				63,100
Stock-based compensation expense					897,650			897,650
Net loss							(12,896,374)	(12,896,374)
Other comprehensive loss						(118,386)		(118,386)
Ending Balance at Mar. 31, 2022				$ 26,383	216,366,884	(167,395)	(72,169,762)	144,056,110
Ending Balance (in shares) at Mar. 31, 2022				26,383,299
Beginning Balance (in shares) at Dec. 31, 2021				26,320,199
Beginning Balance at Dec. 31, 2021				$ 26,320	215,276,186	(49,009)	(59,273,388)	$ 155,980,109
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock upon exercise of stock options (in shares)								72,100
Net loss								$ (24,423,677)
Ending Balance at Jun. 30, 2022				$ 26,392	217,447,080	(181,561)	(83,697,065)	133,594,846
Ending Balance (in shares) at Jun. 30, 2022				26,392,299
Beginning Balance (in shares) at Mar. 31, 2022				26,383,299
Beginning Balance at Mar. 31, 2022				$ 26,383	216,366,884	(167,395)	(72,169,762)	144,056,110
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock upon exercise of stock options				$ 9	27,775			27,784
Issuance of common stock upon exercise of stock options (in shares)				9,000
Stock-based compensation expense					1,052,421			1,052,421
Net loss							(11,527,303)	(11,527,303)
Other comprehensive loss						(14,166)		(14,166)
Ending Balance at Jun. 30, 2022				$ 26,392	$ 217,447,080	$ (181,561)	$ (83,697,065)	$ 133,594,846
Ending Balance (in shares) at Jun. 30, 2022				26,392,299

CONDENSED CONSOLIDATED STATEM_3

CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)	6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021
Cash flows from operating activities:
Net loss	$ (24,423,677)	$ (14,217,316)
Adjustment to reconcile to net loss to net cash used in operating activities:
Depreciation expense	102,263	18,674
Right-of-use asset amortization	285,302	50,333
Intangible asset amortization	15,420
Stock based compensation expense	1,950,071	533,234
Net amortization of premium (accretion of discount) on marketable securities	144,441
(Increase) decrease in:
Accounts receivable	67,615	5,005
Prepaid expenses and other current assets	2,026,298	(555,726)
Other assets	12,550	(946,053)
Increase (decrease) in:
Accounts payable	(154,099)	(48,021)
Accrued expenses	(1,727,466)	2,619,878
Lease liability	(86,141)	(37,271)
Other liabilities	57,111
Net cash used in operating activities	(21,730,312)	(12,577,263)
Cash flows from investing activities:
Purchases of property and equipment	(280,047)	(36,388)
Purchases of marketable securities	(17,989,202)
Maturities of marketable securities	52,828,000
Net cash provided by (used in) investing activities	34,558,751	(36,388)
Cash flows from financing activities:
Proceeds from exercise of stock options	220,895	52,627
Proceeds from exercise of warrants		927,125
Net cash provided by financing activities	220,895	25,768,603
Net increase in cash and cash equivalents	13,049,334	13,154,952
Cash and cash equivalents at beginning of period	74,888,145	37,090,151
Cash and cash equivalents at end of period	87,937,479	50,245,103
Supplemental disclosures of noncash information:
Reduction of right of use asset and lease liability in connection with lease modification	$ 347,739
Deferred offering costs included in accounts payable and accrued expenses		875,078
Series B Preferred Stock
Cash flows from financing activities:
Proceeds from the issuance of preferred stock, net of issuance costs		$ 24,788,851

Organization and Nature of Busi

Organization and Nature of Business	6 Months Ended
	Jun. 30, 2022
Organization and Nature of Business
Organization and Nature of Business	Note 1 – Organization and Nature of Business Immuneering Corporation, a Delaware corporation, (“Immuneering” or the “Company”) was incorporated in 2008. The Company aims to improve patient outcomes by advancing a pipeline of product candidates designed to benefit large populations of patients with cancer and other diseases, developed using the Company’s translational bioinformatics platform. The Company has more than a decade of experience applying translational bioinformatics to generate insights into drug mechanism of action and patient treatment response. Building on this experience, the Company’s disease-agnostic discovery platform enables the Company to create product candidates based on 1) biological insights that are both counterintuitive and deeply rooted in data, and 2) novel chemistry. On October 30, 2019, Immuneering formed a wholly owned subsidiary, Immuneering Securities Corporation (“ISC”), a Massachusetts securities corporation, for the sole purpose of buying, selling and holding securities on the Company’s behalf. On December 22, 2021, the Company acquired all outstanding shares of capital stock of BioArkive, Inc. (“BioArkive”), a California corporation, which as a result became a wholly owned subsidiary. Immuneering, ISC and BioArkive are collectively referred to as “the Company” throughout these condensed consolidated financial statements. The Company is subject to a number of inherent risks associated with any biotechnology company that has substantial expenditures for research and development. These risks include, but are not limited to, the need to obtain adequate additional funding, possible failure of clinical trials or other events demonstrating lack of clinical safety or efficacy of its product candidates, dependence on key personnel, reliance on third-party service providers for manufacturing drug product and conducting clinical trials, the ability to successfully secure its proprietary technology, and risks related to the regulatory approval and commercialization of a product candidate. There can be no assurance that the Company’s research and development program will be successful. In addition, the Company operates in an environment of rapid technological change and is largely dependent on the services of its employees, advisors, and consultants. On August 3, 2021, the Company completed its initial public offering (“IPO”) pursuant to which it issued and sold 8,625,000 shares of its Class A common stock, inclusive of 1,125,000 shares of its Class A common stock sold pursuant to the full exercise of the underwriters’ option to purchase additional shares. The aggregate net proceeds received by the Company from the IPO were $120,318,750, after deducting underwriting discounts and commissions, but before deducting offering costs payable by the Company, which were $2,124,317. Upon the closing of the IPO, all 8,528,078 shares of the Company’s convertible preferred stock then outstanding automatically converted into 11,939,281 shares of Class A common stock. Upon the conversion of the convertible preferred stock, the Company reclassified the carrying value of the convertible preferred stock to common stock (at par value) and additional paid-in capital. To date, the Company has funded its operations through service revenues, and with proceeds from the sale of its capital stock and convertible notes and, most recently, with proceeds from the IPO. The Company has incurred recurring losses over the past several years and as of June 30, 2022, the Company had an accumulated deficit of $83,697,065. The Company expects to continue to generate operating losses for the foreseeable future. The future viability of the Company is dependent on its ability to raise additional capital to finance its operations. The Company’s inability to raise capital as and when needed could have a negative impact on its financial condition and ability to pursue its business strategies. There can be no assurances that additional funding will be available on terms acceptable to the Company, or at all. If the Company is unable to raise additional funds when needed, it may be required to delay, reduce the scope of, or eliminate development programs, which may adversely affect its business and operations. Management considers that there are no conditions or events, in the aggregate, that raise substantial doubt about the entity’s ability to continue as a going concern and estimates that its cash and cash equivalents will be sufficient to fund its operating expenses and capital expenditure requirements for at least 12 months from the issuance date of the consolidated financial statements. The full extent to which coronavirus (“COVID-19”) pandemic will directly or indirectly impact the Company’s business, results of operations and financial condition, including expenses and research and development costs, will depend on future developments that are highly uncertain, including as a result of new information that may emerge concerning COVID-19 and its variants and the actions taken to contain or treat COVID-19 and its variants, as well as the economic impact on local, regional, national and international markets. The Company has considered potential impacts arising from the pandemic related to COVID-19 and its variants and is not presently aware of any events or circumstances that would require the Company to update its estimates, judgements or revise the carrying values of its assets or liabilities.

Summary of Significant Accounti

Summary of Significant Accounting Policies	6 Months Ended
	Jun. 30, 2022
Summary of Significant Accounting Policies
Summary of Significant Accounting Policies	Note 2 - Summary of Significant Accounting Policies Basis of Presentation The condensed consolidated financial statements have been prepared in accordance with accounting standards set by the Financial Accounting Standards Board (“FASB”). The FASB sets generally accepted accounting principles (“GAAP”) to ensure the condensed consolidated financial statements are consistently reported. References to GAAP issued by the FASB in these footnotes are to the FASB Accounting Standards Codifications (“ASC”). The condensed consolidated financial statements include the accounts of the Company and its wholly owned subsidiary. All intercompany balances and transactions have been eliminated in consolidation. There have been no material changes to the accounting policies of the Company as those set forth in Note 2 to the audited consolidated financial statements contained in the Annual Report on Form 10-K for the fiscal period ended December 31, 2021. Unaudited Interim Financial Information The unaudited interim condensed consolidated financial statements of the Company have been prepared, without audit, in accordance with GAAP and in accordance with the rules and regulations of the Securities and Exchange Commission (“SEC”) regarding interim financial reporting. Certain information and footnote disclosures normally included in the annual financial statements prepared in accordance with GAAP have been omitted from the unaudited interim condensed consolidated financial statements, as is permitted by such rules and regulations. While we believe that the disclosures presented are adequate in order to make the information not misleading, these unaudited interim condensed consolidated financial statements should be read in conjunction with the Company’s audited consolidated financial statements and notes for the year ended December 31, 2021. It is management’s opinion that these financial statements include all normal and recurring adjustments necessary for a fair presentation of the Company’s financial position, operating results and cash flows. Revenues and net loss for any interim period are not necessarily indicative of future or annual results. Use of Estimates The preparation of financial statements in conformity with GAAP requires management to make estimates and assumptions that affect the reported amounts of assets, liabilities, revenues and expenses during the reporting periods. These estimates and assumptions are based on current facts, historical experience and various other factors believed to be reasonable under the circumstances, the results of which form the basis for making judgements about the carrying values of assets, liabilities and the recording of expenses that are not readily apparent from other sources. Significant estimates reflected in these condensed consolidated financial statements included but are not limited to, the research and development expenses, determination of fair value of stock-based awards, the valuation of common stock prior to the IPO, and the right-to-use assets and operating lease liability. Actual results may differ materially and adversely from these estimates. Goodwill Goodwill represents the excess of the fair value of the acquiree over the recognized bases of the net identifiable assets acquired and includes the future economic benefits from other assets that could not be individually identified and separately recognized. Goodwill is not amortized, but instead is periodically reviewed for impairment and an impairment charge is recorded in the periods in which the recorded carrying value of goodwill exceeds its fair value. On a quarterly basis, the Company performs a review of its business to determine if events or changes in circumstances have occurred which could have a material adverse effect on the fair value of the Company and its goodwill. If such events or changes in circumstances were deemed to have occurred, the Company would perform an impairment test of goodwill as of the end of the quarter and record any noted impairment loss. The goodwill test is performed at least annually, or more frequently if events or changes in circumstances indicate that the asset might be impaired. The Company performs its annual impairment test during the fourth quarter of each fiscal year. There were no impairments in 2021. Subsequent to December 31, 2021, the Company’s market capitalization has declined which may be an indicator of impairment. The Company will continue to assess the impact of its market capitalization and any other indicators of potential impairment. It is possible that if the Company’s market capitalization decline is more than temporary, or if other indicators of impairment are identified, an interim impairment analysis may be necessary, which could result in an impairment of goodwill, intangible assets and other long-lived assets in 2022. ​ Recently Issued Accounting Pronouncements From time to time, new accounting pronouncements are issued by the FASB or other standard setting bodies and adopted by the Company as of the specified effective date. The Company is an “emerging growth company” as defined in the Jumpstart Our Business Startups Act of 2012, as amended (“JOBS Act”). The JOBS Act provides that an emerging growth company can take advantage of an extended transition period for complying with new or revised accounting standards. Thus, an emerging growth company can delay the adoption of certain accounting standards until those standards would otherwise apply to private companies. The Company elected to avail itself of this extended transition period and, as a result, we will not be required to adopt new or revised accounting standards on the relevant dates on which adoption of such standards is required for other public companies. In 2016, the FASB issued Accounting Standards Update (“ASU”) No. 2016-13, Financial Instruments – Credit Losses (Topic 326): Measurement of Credit Losses on Financial Statements. The new standard, as amended, requires that expected credit losses relating to financial assets measured on an amortized cost basis and available-for-sale debt securities be recorded through an allowance for credit losses. It also limits the amount of credit losses to be recognized for available-for-sale debt securities to the amount by which carrying value exceeds fair value and also requires the reversal of previously recognized credit losses if fair value increases. The targeted transition relief standard allows filers an option to irrevocably elect the fair value option of ASC 825-10, Financial Instruments - Overall, applied on an instrument-by-instrument basis for eligible instruments. ASU 2016-13, Financial Instruments - Credit Losses (Topic 326) will become effective for the Company on January 1, 2023. The Company is currently evaluating the new guidance and assessing the potential impact on its condensed consolidated financial statements. In January 2017, the FASB issued ASU 2017-04, Intangibles - Goodwill and Other (Topic 350 ) ​

Marketable Securities

Marketable Securities	6 Months Ended
	Jun. 30, 2022
Marketable Securities
Marketable Securities	​ Note 3 – Marketable Securities Our marketable securities are classified as available-for-sale pursuant to ASC 320, Investments – Debt and Equity Securities ​ Marketable securities as of June 30, 2022 consisted of the following: ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ June 30, 2022 ​ Amortized Cost Unrealized Gains Unrealized Losses Fair Value Assets: ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Current: ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ U.S. Treasuries ​ $ 21,748,299 ​ $ - ​ $ (125,724) ​ $ 21,622,575 Government securities ​ ​ 8,600,549 ​ ​ - ​ ​ (29,869) ​ ​ 8,570,680 Commercial paper ​ ​ 9,995,295 ​ ​ - ​ ​ (24,675) ​ ​ 9,970,620 Total marketable securities ​ $ 40,344,143 ​ $ - ​ $ (180,268) ​ $ 40,163,875 ​ Marketable securities as of December 31, 2021 consisted of the following: ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ December 31, 2021 ​ Amortized Cost Unrealized Gains Unrealized Losses Fair Value Assets: ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Current: ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ U.S. Treasuries ​ $ 42,147,385 ​ $ - ​ $ (28,575) ​ $ 42,118,810 Government securities ​ ​ 19,218,057 ​ ​ - ​ ​ (13,689) ​ ​ 19,204,368 Commercial paper ​ ​ 12,992,165 ​ ​ 57 ​ ​ (4,197) ​ ​ 12,988,025 Total Current ​ ​ 74,357,607 ​ ​ 57 ​ ​ (46,461) ​ ​ 74,311,203 ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Non-current: ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ U.S. Treasuries ​ ​ 999,186 ​ ​ - ​ ​ (2,626) ​ ​ 996,560 Government securities ​ ​ - ​ ​ - ​ ​ - ​ ​ - Total Non-current ​ ​ 999,186 ​ ​ - ​ ​ (2,626) ​ ​ 996,560 Total marketable securities ​ $ 75,356,793 ​ $ 57 ​ $ (49,087) ​ $ 75,307,763 ​

Fair Value Measurements

Fair Value Measurements	6 Months Ended
	Jun. 30, 2022
Fair Value Measurements
Fair Value Measurements	Note 4 – Fair Value Measurements We record cash equivalents and marketable securities at fair value. ASC 820, Fair Value Measurements and Disclosures, establishes a fair value hierarchy for those instruments measured at fair value that distinguishes between assumptions based on market data (observable inputs) and our own assumptions (unobservable inputs). The hierarchy consists of three levels: Level 1 Level 2 Level 3 The following table summarizes our cash equivalents and marketable securities measured at fair value on a recurring basis as of June 30, 2022: ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Level 1 ​ ​ Level 2 ​ ​ Level 3 ​ ​ Total Assets: ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Cash equivalents ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Money market ​ $ 38,003,223 ​ $ - ​ $ - ​ $ 38,003,223 Commercial paper ​ ​ - ​ ​ 7,996,140 ​ ​ - ​ ​ 7,996,140 Total cash equivalents ​ ​ 38,003,223 ​ ​ 7,996,140 ​ ​ - ​ ​ 45,999,363 ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Marketable securities: ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ U.S. Treasuries ​ $ 21,622,575 ​ $ - ​ $ - ​ $ 21,622,575 Government securities ​ ​ - ​ ​ 8,570,680 ​ ​ - ​ ​ 8,570,680 Commercial paper ​ ​ - ​ ​ 9,970,620 ​ ​ - ​ ​ 9,970,620 Total marketable securities ​ ​ 21,622,575 ​ ​ 18,541,300 ​ ​ - ​ ​ 40,163,875 Total cash equivalents and marketable securities ​ $ 59,625,798 ​ $ 26,537,440 ​ $ - ​ $ 86,163,238 ​ Cash equivalents and marketable securities have been initially valued at the transaction price and subsequently, at the end of each reporting period, valued utilizing third-party pricing services or other observable market data. The pricing services utilize industry standard valuation models, including both income and market-based approaches, and observable market inputs to determine value. After completing our valuation procedures, we did not adjust or override any fair value measurements provided by the pricing services as of June 30, 2022. There have been no changes to the valuation methods during the three months ended June 30, 2022. There were no transfers between Level 1 and Level 2 and we had no financial assets or liabilities The following table summarizes our cash equivalents and marketable securities measured at fair value on a recurring basis as of December 31, 2021: ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Level 1 ​ ​ Level 2 ​ ​ Level 3 ​ ​ Total Assets: ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Cash equivalents ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Money market ​ $ 33,961,344 ​ $ - ​ $ - ​ $ 33,961,344 Commercial paper ​ ​ - ​ ​ 2,000,000 ​ ​ - ​ ​ 2,000,000 Total cash equivalents ​ ​ 33,961,344 ​ ​ 2,000,000 ​ ​ - ​ ​ 35,961,344 ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Marketable securities: ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ U.S. Treasuries ​ $ 43,115,370 ​ $ - ​ $ - ​ $ 43,115,370 Government securities ​ ​ - ​ ​ 19,204,368 ​ ​ - ​ ​ 19,204,368 Commercial paper ​ ​ - ​ ​ 12,988,025 ​ ​ - ​ ​ 12,988,025 Total marketable securities ​ ​ 43,115,370 ​ ​ 32,192,393 ​ ​ - ​ ​ 75,307,763 Total cash equivalents and marketable securities ​ $ 77,076,714 ​ $ 34,192,393 ​ $ - ​ $ 111,269,107 ​ ​

Property and Equipment, net

Property and Equipment, net	6 Months Ended
	Jun. 30, 2022
Property and Equipment, net
Property and Equipment, net	Note 5 – Property and Equipment, net Property and equipment, net consisted of the following: ​ ​ ​ ​ ​ ​ ​ ​ ​ June 30, December 31, ​ ​ 2022 ​ 2021 ​ ​ ​ ​ ​ ​ ​ Computer equipment ​ $ 318,793 ​ $ 281,666 Furniture and fixtures ​ 84,477 ​ 84,477 Lab equipment ​ ​ 650,727 ​ ​ 463,182 Leasehold improvements ​ ​ 207,492 ​ ​ 152,117 Total ​ 1,261,489 ​ 981,442 Accumulated depreciation ​ (276,482) ​ (174,219) Property and equipment, net ​ $ 985,007 ​ $ 807,223 ​ Depreciation expense totaled $54,560 and $9,807 for the three months ended June 30, 2022 and 2021, respectively. Depreciation expense totaled $102,263 and $18,674 for the six months ended June 30, 2022 and 2021, respectively.

Business Combination

Business Combination	6 Months Ended
	Jun. 30, 2022
Business Combination
Business Combination.	Note 6 – Business Combination BioArkive Acquisition On December 22, 2021, the Company completed the acquisition of all outstanding shares of capital stock of BioArkive, Inc., a California corporation, for a market value of $8.75 million. ​ BioArkive is a San Diego based contract research organization that has previously provided preclinical research services and biosample storage to the Company and other biotechnology companies. BioArkive is in the process of being fully integrated into the Company to exclusively support the Company's internal preclinical research activities for its oncology pipeline. ​ In connection with the acquisition, the Company has assumed the obligations under BioArkive’s three lease agreements. ​ The purchase price was paid by Immuneering through the issuance of an aggregate of 379,635 shares of Immuneering’s Class A common stock. The number of shares of common stock issued was calculated using a value based on the average of the daily volume weighted average prices of the common stock on the Nasdaq Stock Exchange for the 30-trading day period ending on and including the trading day immediately prior to the closing date. The sellers of BioArkive were restricted from selling these shares for a six-month period from the date of the acquisition. As such, we estimated that there was an approximate 10% discount for the lack of marketability of the shares. The fair value of the purchase price in the acquisition was $7,875,000. ​ Prior to the acquistion, Brett Hall, Chief Scientific Officer of Immuneering and the Founder and Chairman of the board of directors of BioArkive, held the majority of the outstanding shares of BioArkive capital stock. BioArkive provided contract services to the Company. Research and development expenses in the consolidated statement of operations include the cost of services provided by BioArkive to the Company which amounted to $4,548,780 in 2021 through the date of the acquisition. The results of BioArkive’s operations are included in accounts payable or accrued contract research expenses in the consolidated balance sheets. ​ Assets Acquired and Liabilities Assumed at Fair Value ​ The BioArkive acquisition has been accounted for using the acquisition method of accounting. This method requires assets acquired and liabilities assumed in a business combination to be recognized at their fair values as of the acquisition date. As of March 31, 2022, the purchase accounting had been finalized, and there was an immaterial measurement period adjustment related to accrued expenses and goodwill. No other adjustments were identified. ​ Intangible Assets ​ The estimated fair value of the intangible assets was determined using the relief from royalty approach. ​ Goodwill ​ Goodwill is the excess of the consideration transferred over the net assets recognized and represents the expected cost savings of the combined company and assembled workforce. One of the key factors that contributes to the recognition of goodwill, and a driver for the Company's acquisition of BioArkive, is the planned investment in the internal preclinical research activities for our oncology pipeline. Goodwill recognized as a result of this acquisition is non-deductible for income tax purposes. ​ Pro forma results are not presented for this acquisition as they are not material to the consolidated results of the Company’s operations. ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Preliminary Valuation ​ Measurement Period Adjustment ​ Final Valuation ​ Weighted Average Life Cash ​ $ 70,348 ​ $ - ​ $ 70,348 ​ ​ Other currents assets ​ ​ 225,790 ​ ​ - ​ ​ 225,790 ​ ​ Other long term assets ​ ​ 87,796 ​ ​ - ​ ​ 87,796 ​ ​ Property and equipment, net ​ ​ 727,539 ​ ​ - ​ ​ 727,539 ​ ​ Right of use assets ​ ​ 4,824,700 ​ ​ - ​ ​ 4,824,700 ​ ​ Intangible asset ​ ​ ​ ​ ​ - ​ ​ ​ ​ ​ Technology ​ ​ 439,000 ​ ​ - ​ ​ 439,000 ​ 15 years Goodwill ​ ​ 6,701,726 ​ ​ 11,295 ​ ​ 6,690,431 ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Total assets acquired ​ ​ 13,076,899 ​ ​ - ​ ​ 13,065,604 ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Accounts payable, accrued expenses and other liabilities ​ ​ 69,714 ​ ​ (11,295) ​ ​ 58,419 ​ ​ Deferred tax liabilities ​ ​ 307,485 ​ ​ - ​ ​ 307,485 ​ ​ Lease liabilities ​ ​ 4,824,700 ​ ​ - ​ ​ 4,824,700 ​ ​ Net assets acquired ​ $ 7,875,000 ​ $ - ​ $ 7,875,000 ​ ​ ​

Accrued Expenses

Accrued Expenses	6 Months Ended
	Jun. 30, 2022
Accrued Expenses
Accrued Expenses	Note 7 – Accrued Expenses Accrued expenses consisted of the following: ​ ​ ​ ​ ​ ​ ​ ​ ​ June 30, December 31, ​ ​ 2022 ​ 2021 ​ ​ ​ ​ ​ ​ ​ Accrued professional services ​ $ 251,271 ​ $ 250,977 Accrued employee expenses ​ 1,591,656 ​ 2,917,282 Accrued contract research expenses ​ 335,658 ​ 585,416 Accrued other ​ ​ 48,102 ​ ​ 211,772 Total ​ $ 2,226,687 ​ $ 3,965,447 ​

Preferred Stock

Preferred Stock	6 Months Ended
	Jun. 30, 2022
Preferred Stock
Preferred Stock	Note 8 – Preferred Stock Series B Preferred Stock In April and May 2021, 2,412,853 shares of the second tranche of Series B Preferred Stock were issued based on the voluntary election of substantially all of the holders of Series B Preferred Stock. The Company received gross proceeds of $24,799,786. The Company incurred issuance costs of $10,935 in connection with the second tranche of Series B Preferred Stock. Upon the closing of the IPO on August 3, 2021, all 8,528,078 shares of the Company’s convertible preferred stock then outstanding automatically converted into 11,939,281 shares of Class A common stock.

Common Stock

Common Stock	6 Months Ended
	Jun. 30, 2022
Common Stock.
Common Stock	Note 9 - Common Stock The Company had 200,000,000 authorized shares of Class A common stock, $0.001 par value per share as of June 30, 2022 and December 31, 2021 of which 26,392,299 and 26,320,199 were issued outstanding As of June 30, 2022 and December 31, 2021, the following number of shares of Class A common stock have been reserved: ​ ​ ​ ​ ​ ​ ​ June 30, December 31, ​ ​ 2022 ​ 2021 ​ ​ ​ ​ ​ Exercise of common stock options 3,827,454 2,859,544 ​ 3,827,454 2,859,544 ​ The Company had 20,000,000 authorized shares of Class B common stock, $0.001 par value per share as of June 30, 2022 and December 31, 2021, of which no shares have been issued nor are outstanding. The holders of Class B common stock have no voting rights. Dividends may be paid when, and if, declared by the Board of Directors, subject to the limitations, powers and preferences granted to the preferred stockholders and on a proportionate basis with holders of Class A common stock. IPO On August 3, 2021, the Company completed its initial public offering pursuant to which it issued and sold 8,625,000 shares of its Class A common stock, inclusive of 1,125,000 shares of its Class A common stock sold pursuant to the full exercise of the underwriters’ option to purchase additional shares. The aggregate net proceeds received by the Company from the IPO were $120,318,750, after deducting underwriting discounts and commissions, but before deducting offering costs payable by the Company, which were $2,124,317. Upon the closing of the IPO, all 8,528,078 shares of the Company’s convertible preferred stock then outstanding automatically converted into 11,939,281 shares of Class A common stock. Upon the conversion of the convertible preferred stock, the Company reclassified the carrying value of the convertible preferred stock to common stock (at par value) and additional paid-in capital. ​ On August 3, 2021 in connection with the closing of the IPO, the Company filed a restated certificate of incorporation, which amended and restated the Company’s certificate of incorporation to, among other things: (i) increase the number of authorized shares of common stock to 200,000,000 shares of Class A common stock, 20,000,000 shares of Class B common stock, par value $0.001 per share, and (ii) authorize 10,000,000 shares of Preferred Stock; and (iii) authorize the Board of Directors to establish the rights, preferences and restrictions on any unissued series of Preferred Stock.

Net Loss Per Share Attributable

Net Loss Per Share Attributable to Common Stockholders	6 Months Ended
	Jun. 30, 2022
Net Loss Per Share Attributable to Common Stockholders
Net Loss Per Share Attributable to Common Stockholders	Note 10 - Net Loss Per Share Attributable to Common Stockholders Net loss per share of common stock is computed using the two-class method required for multiple classes of common stock and participating securities based upon their respective rights to receive dividends as if all income for the period has been distributed. The rights, including the liquidation and dividend rights and sharing of losses, of the Class A and Class B common stock are identical, other than voting rights. As the liquidation and dividend rights and sharing of losses are identical, the undistributed earnings are allocated on a proportionate basis and the resulting net loss per share attributed to common stockholders is therefore the same for Class A and Class B common stock on an individual or combined basis. The Company’s participating securities include the Company’s Preferred Stock, as the holders are entitled to receive noncumulative dividends in the event that a dividend is paid on common stock. The holders of Preferred Stock do not have a contractual obligation to share in losses of the Company, and therefore during periods of loss there is no allocation required under the two-class method. Basic net loss per share attributable to common stockholders is calculated by dividing the net loss attributable to common stockholders by the weighted-average number of shares of common stock outstanding during the period, adjusted for outstanding shares that are subject to repurchase. Diluted net loss per share is computed by giving effect to all potentially dilutive securities outstanding for the period using the treasury stock method or the if-converted method based on the nature of such securities. The Company has reported net losses for all periods presented, therefore diluted net loss per common share attributable to common stockholders is the same as basic net loss per common share attributable to common stockholders, because potentially dilutive common shares are not assumed to have been issued if their effect is anti-dilutive. Basic and diluted net loss per share attributable to common stockholders was calculated at June 30, 2022 and 2021 as follows: ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Three Months Ended June 30, Six Months Ended June 30, ​ ​ 2022 2021 ​ 2022 2021 ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Numerator: ​ ​ ​ ​ Net loss ​ $ (11,527,303) ​ $ (7,987,665) ​ $ (24,423,677) ​ $ (14,217,316) Denominator - basic and diluted: ​ ​ ​ ​ Weighted-average common shares outstanding, basic and diluted ​ 26,386,343 ​ 4,954,553 ​ 26,372,787 ​ 4,952,352 Net loss per share - basic and diluted ​ $ (0.44) ​ $ (1.61) ​ $ (0.93) ​ $ (2.87) ​ The following table sets forth the potentially dilutive securities that have been excluded from the calculation of diluted net loss per share because to include them would be anti-dilutive (in common stock equivalent shares) at June 30, 2022 and 2021: ​ ​ ​ ​ ​ ​ ​ 2022 2021 ​ ​ ​ ​ ​ Options to purchase common stock 3,827,454 2,668,327 Total shares of common stock equivalents 3,827,454 2,668,327 ​

Stock-Based Compensation

Stock-Based Compensation	6 Months Ended
	Jun. 30, 2022
Stock-Based Compensation
Stock-Based Compensation	Note 11 – Stock-Based Compensation During 2015, the Company established the Long Term Incentive Plan (“Incentive Plan”), under which incentive stock options, nonqualified stock options, restricted stock or other awards may be awarded to employees, directors or consultants of the Company. The options typically vest over a four On July 23, 2021, the Company’s Board of Directors adopted, and on July 23, 2021 its stockholders approved, the 2021 Incentive Award Plan (the “2021 Plan”), which became effective on July 29, 2021. The 2021 Plan provides for the grant of incentive stock options, stock appreciation rights, restricted stock awards, restricted stock units, and other stock-based awards. The number of shares reserved for issuance under the 2021 Plan was initially equal to 2,590,000 plus an annual increase on the first day of each calendar year, beginning on January 1, 2022 and ending on and including January 1, 2031, equal to the lesser of (i) 4% of the aggregate number of shares of Class A common stock outstanding on the final day of the immediately preceding calendar year and (ii) such smaller number of shares of Class A common stock as determined by the Board of Directors. No more than 15,350,000 shares of Class A common stock may be issued under the 2021 Plan upon the exercise of incentive stock options. Shares issued under the 2021 Plan may be authorized but unissued shares, shares purchased on the open market or treasury shares. If an award under the 2021 Plan expires, lapses or is terminated, exchanged for or settled in cash, surrendered, repurchased, cancelled without having been fully exercised/settled or forfeited, any unused shares subject to the award will, as applicable, become or again be available for new grants under the 2021 Plan. In addition, shares subject to stock options issued under the Incentive Plan may become available for issuance under the 2021 Plan to the extent such stock options are canceled, forfeited, exchanged, settled in cash or otherwise terminated. As of June 30, 2022, there were 2,311,230 shares available for future issuance under the 2021 Plan. On July 23, 2021, the Company’s Board of Directors adopted, and on July 23, 2021 its stockholders approved, the 2021 Employee Stock Purchase Plan (the “2021 ESPP”), which became effective on July 29, 2021. A total of 250,000 shares of Class A common stock were initially reserved for issuance under this plan. The number of shares of Class A common stock that may be issued under the 2021 ESPP will automatically increase on the first day of each calendar year, beginning on January 1, 2022 and ending on and including January 1, 2031, equal to the lesser of (i) 1% of the shares of Class A common stock outstanding on the final day of the immediately preceding calendar year and (ii) such smaller number of shares of Class A common stock as determined by the board of directors, provided that not more than 3,340,000 shares of Class A common stock may be issued under the 2021 ESPP. As of June 30, 2022, no shares had been issued under the 2021 ESPP. During the three and six months ended June 30, 2022, the Company recognized stock-based compensation expense of $1,052,421 and $1,950,071 , respectively. During the three and six months ended June 30, 2021, the Company recognized stock-based compensation expense of $351,009 and $533,234 , respectively. As of June 30, 2022, compensation expense remaining to be recognized for outstanding stock options was $12,585,048 and to be recognized over a weighted-average period of 2.83 years. The fair value of options granted is calculated on the grant date using the Black-Scholes option valuation model. The Company historically has been a private company and lacks company-specific historical and implied volatility information. Therefore, it estimates its expected stock volatility based on the historical volatility of a publicly traded set of peer public companies and expects to continue to do so until such time as it has adequate historical data regarding the volatility of its own traded stock price. For the six months ended June 30, 2022, the Company granted 1,067,410 shares of stock options at a weighted-average grant date fair value of $9.50 . The Company used the following assumptions in its application of the Black-Scholes option pricing model for grants during the six months ended June 30, 2022 and 2021: ​ ​ ​ ​ ​ ​ ​ ​ Six Months Ended June 30, ​ 2022 2021 ​ ​ ​ ​ ​ Weighted-average risk-free interest rate ​ 1.35% - 3.31% ​ 1.04% - 1.71% Expected term (in years) ​ 5.00 - 10 years ​ 5.83 - 10 years Expected dividend yield ​ 0% ​ 0% Expected volatility ​ 65.24% - 78.12% ​ 68.92% - 80.99% ​ The following table summarizes the stock option activity during the six months ended June 30, 2022 under the Plan: ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Weighted ​ ​ ​ ​ ​ ​ Weighted- ​ Average ​ ​ ​ ​ ​ ​ ​ Average ​ Remaining ​ ​ ​ ​ ​ Number of ​ Exercise Price ​ Contractual ​ Aggregate ​ ​ Options ​ per Share Term (in Years) ​ Intrinsic Value ​ ​ ​ Outstanding at of December 31, 2021 2,859,544 ​ $ 6.55 8.30 ​ Granted 1,067,410 ​ ​ 9.50 ​ ​ ​ Exercised (72,100) ​ ​ 3.02 ​ ​ ​ Cancelled (27,400) ​ ​ 6.58 ​ ​ ​ Outstanding at June 30, 2022 3,827,454 ​ $ 7.43 ​ 8.31 ​ $ 3,669,555 ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Vested and exercisable at June 30, 2022 1,539,603 ​ $ 4.59 7.33 ​ $ 2,820,514 Vested and expected to vest at June 30, 2022 ​ 3,827,454 ​ $ 7.43 8.31 ​ $ 3,669,555 ​ For the three months ended June 30, 2022 and 2021, the Company recognized share-based compensation expense recognized on the accompanying condensed consolidated statements of operations as follows: ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Three Months Ended June 30, ​ Six Months Ended June 30, ​ 2022 2021 2022 2021 ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Cost of revenue ​ $ 4,014 ​ $ 22,367 ​ $ 8,644 ​ $ 44,882 Research and development ​ 504,938 ​ 168,725 ​ 937,657 ​ 222,732 General and administrative ​ 543,469 ​ 159,917 ​ 1,003,770 ​ 265,620 Total ​ $ 1,052,421 ​ $ 351,009 ​ $ 1,950,071 ​ $ 533,234 ​

Commitments and Contingencies

Commitments and Contingencies	6 Months Ended
	Jun. 30, 2022
Commitments and Contingencies.
Commitments and Contingencies	Note 12 – Commitments and Contingencies Operating Leases The Company leases office space in Cambridge, Massachusetts, New York, New York and San Francisco, California, pursuant to short-term arrangements. The Cambridge and San Francisco leases are on a month-to-month basis, requiring one As of June 30, 2022, total future minimum lease payments for its short-term leases in Cambridge, Massachusetts, New York, New York and San Francisco, California was $39,600 due in 2022. In October 2020, the Company entered into an office lease (“Via Frontera Lease”) in San Diego, California with a lease term of 67 months. At the lease commencement date, a right-to-use asset and lease liability was recognized by the Company for $637,863. In January 2022, the Company exercised its option to terminate the Via Frontera Lease 20 months early. The lease will terminate on October 1, 2023. This was accounted for as a lease modification which reduces the term of the existing lease and the Company adjusted the value of its right-of-use asset and operating lease liability by $347,739 using an incremental borrowing rate of approximately 6% . ​ The modification is reflected as a non-cash operating activity in the statement of cash flows for the six months ended June 30, 2022. ​ The Company subsequently entered into a sublease of the Via Frontera Lease, the term of which commenced in March 2022 and continues through the full remaining obligation. Sublease income will be accounted for as a reduction of rent expense in the statement of operations. ​ As part of the BioArkive acquisition, the Company assumed the obligations of three leases in San Diego, California. One is for 38,613 square feet of office and laboratory space, under a lease that terminates on April 30, 2032, the second is for a 6,100 square feet of office and laboratory space under a lease that terminates on December 31, 2022 (the “Site 2 Lease”), and the third is for a lease for 4,760 square feet of office and laboratory space under a lease that terminates on March 31, 2024. As a result, the Company recorded right-to-use assets and lease liabilities of $4,824,700 on the acquisition date of December 22, 2021 Future minimum lease payments for operating leases with initial or remaining terms in excess of one year at June 30, 2022 were as follows: ​ ​ ​ ​ ​ ​ Amount Remainder of 2022 ​ $ 331,740 2023 ​ 843,463 2024 ​ 732,546 2025 ​ 739,689 2026 ​ 761,877 Thereafter ​ 4,467,246 Total future lease payments ​ 7,876,561 Less: Imputed interest ​ (2,945,504) Total lease liabilities ​ $ 4,931,057 Current portion lease liability ​ $ 286,374 Lease liability, noncurrent ​ 4,644,683 Total lease liability ​ $ 4,931,057 ​ Quantitative information regarding the Company’s leases for the six months ended June 30, 2022 and 2021 is as follows: ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ June 30, June 30, ​ ​ 2022 ​ 2021 ​ Lease costs: ​ ​ ​ ​ ​ Operating lease cost ​ $ 527,413 ​ $ 68,502 Short-term lease cost ​ 164,373 ​ 117,352 Sublease income ​ (95,470) ​ — ​ Total lease costs ​ $ 596,316 ​ $ 185,854 Cash paid for amounts included in the measurement of lease liabilities: ​ ​ Operating cash flows from operating leases ​ $ 328,250 ​ $ 55,440 Operating cash flows from short-term leases ​ 164,373 ​ 117,352 ​ ​ $ 492,623 ​ $ 172,792 ​ Weighted-average remaining lease term - operating leases ​ 9.49 years ​ 4.83 years ​ Weighted-average discount rate - operating leases ​ 9.3% ​ 6.0% ​ ​ As the Company’s leases typically do not provide an implicit rate, the Company uses an estimate of its incremental borrowing rate based on the information available at the lease commencement date in determining the present value of lease payments. Litigation From time to time, the Company may have certain contingent liabilities that arise in the ordinary course of its business activities and may be exposed to litigation in connection with its products and operations. The Company’s policy is to assess the likelihood of any adverse judgments or outcomes related to legal matters, as well as ranges of probable losses. When it is probable that future expenditures will be made and can be reasonably estimated the Company will accrue a liability for such matters. Significant judgement is required to determine both probability and estimated amount. The Company is not aware of any material legal matters. Clinical Research Contracts The Company may enter into contracts in the normal course of business with clinical research organizations for clinical trials, with contract manufacturing organizations for clinical supplies, and with other vendors for preclinical studies, supplies and other services for our operating purposes. These contracts generally provide for termination with a 30-day notice. ​

Summary of Significant Accoun_2

Summary of Significant Accounting Policies (Policies)	6 Months Ended
	Jun. 30, 2022
Summary of Significant Accounting Policies
Basis of Presentation	Basis of Presentation The condensed consolidated financial statements have been prepared in accordance with accounting standards set by the Financial Accounting Standards Board (“FASB”). The FASB sets generally accepted accounting principles (“GAAP”) to ensure the condensed consolidated financial statements are consistently reported. References to GAAP issued by the FASB in these footnotes are to the FASB Accounting Standards Codifications (“ASC”). The condensed consolidated financial statements include the accounts of the Company and its wholly owned subsidiary. All intercompany balances and transactions have been eliminated in consolidation. There have been no material changes to the accounting policies of the Company as those set forth in Note 2 to the audited consolidated financial statements contained in the Annual Report on Form 10-K for the fiscal period ended December 31, 2021.
Unaudited Interim Financial Information	Unaudited Interim Financial Information The unaudited interim condensed consolidated financial statements of the Company have been prepared, without audit, in accordance with GAAP and in accordance with the rules and regulations of the Securities and Exchange Commission (“SEC”) regarding interim financial reporting. Certain information and footnote disclosures normally included in the annual financial statements prepared in accordance with GAAP have been omitted from the unaudited interim condensed consolidated financial statements, as is permitted by such rules and regulations. While we believe that the disclosures presented are adequate in order to make the information not misleading, these unaudited interim condensed consolidated financial statements should be read in conjunction with the Company’s audited consolidated financial statements and notes for the year ended December 31, 2021. It is management’s opinion that these financial statements include all normal and recurring adjustments necessary for a fair presentation of the Company’s financial position, operating results and cash flows. Revenues and net loss for any interim period are not necessarily indicative of future or annual results.
Use of Estimates	Use of Estimates The preparation of financial statements in conformity with GAAP requires management to make estimates and assumptions that affect the reported amounts of assets, liabilities, revenues and expenses during the reporting periods. These estimates and assumptions are based on current facts, historical experience and various other factors believed to be reasonable under the circumstances, the results of which form the basis for making judgements about the carrying values of assets, liabilities and the recording of expenses that are not readily apparent from other sources. Significant estimates reflected in these condensed consolidated financial statements included but are not limited to, the research and development expenses, determination of fair value of stock-based awards, the valuation of common stock prior to the IPO, and the right-to-use assets and operating lease liability. Actual results may differ materially and adversely from these estimates.
Goodwill Impairment	Goodwill Goodwill represents the excess of the fair value of the acquiree over the recognized bases of the net identifiable assets acquired and includes the future economic benefits from other assets that could not be individually identified and separately recognized. Goodwill is not amortized, but instead is periodically reviewed for impairment and an impairment charge is recorded in the periods in which the recorded carrying value of goodwill exceeds its fair value. On a quarterly basis, the Company performs a review of its business to determine if events or changes in circumstances have occurred which could have a material adverse effect on the fair value of the Company and its goodwill. If such events or changes in circumstances were deemed to have occurred, the Company would perform an impairment test of goodwill as of the end of the quarter and record any noted impairment loss. The goodwill test is performed at least annually, or more frequently if events or changes in circumstances indicate that the asset might be impaired. The Company performs its annual impairment test during the fourth quarter of each fiscal year. There were no impairments in 2021. Subsequent to December 31, 2021, the Company’s market capitalization has declined which may be an indicator of impairment. The Company will continue to assess the impact of its market capitalization and any other indicators of potential impairment. It is possible that if the Company’s market capitalization decline is more than temporary, or if other indicators of impairment are identified, an interim impairment analysis may be necessary, which could result in an impairment of goodwill, intangible assets and other long-lived assets in 2022.
Recently Issued Accounting Pronouncements	Recently Issued Accounting Pronouncements From time to time, new accounting pronouncements are issued by the FASB or other standard setting bodies and adopted by the Company as of the specified effective date. The Company is an “emerging growth company” as defined in the Jumpstart Our Business Startups Act of 2012, as amended (“JOBS Act”). The JOBS Act provides that an emerging growth company can take advantage of an extended transition period for complying with new or revised accounting standards. Thus, an emerging growth company can delay the adoption of certain accounting standards until those standards would otherwise apply to private companies. The Company elected to avail itself of this extended transition period and, as a result, we will not be required to adopt new or revised accounting standards on the relevant dates on which adoption of such standards is required for other public companies. In 2016, the FASB issued Accounting Standards Update (“ASU”) No. 2016-13, Financial Instruments – Credit Losses (Topic 326): Measurement of Credit Losses on Financial Statements. The new standard, as amended, requires that expected credit losses relating to financial assets measured on an amortized cost basis and available-for-sale debt securities be recorded through an allowance for credit losses. It also limits the amount of credit losses to be recognized for available-for-sale debt securities to the amount by which carrying value exceeds fair value and also requires the reversal of previously recognized credit losses if fair value increases. The targeted transition relief standard allows filers an option to irrevocably elect the fair value option of ASC 825-10, Financial Instruments - Overall, applied on an instrument-by-instrument basis for eligible instruments. ASU 2016-13, Financial Instruments - Credit Losses (Topic 326) will become effective for the Company on January 1, 2023. The Company is currently evaluating the new guidance and assessing the potential impact on its condensed consolidated financial statements. In January 2017, the FASB issued ASU 2017-04, Intangibles - Goodwill and Other (Topic 350 )

Marketable Securities (Tables)

Marketable Securities (Tables)	6 Months Ended
	Jun. 30, 2022
Marketable Securities
Schedule of marketable securities	​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ June 30, 2022 ​ Amortized Cost Unrealized Gains Unrealized Losses Fair Value Assets: ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Current: ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ U.S. Treasuries ​ $ 21,748,299 ​ $ - ​ $ (125,724) ​ $ 21,622,575 Government securities ​ ​ 8,600,549 ​ ​ - ​ ​ (29,869) ​ ​ 8,570,680 Commercial paper ​ ​ 9,995,295 ​ ​ - ​ ​ (24,675) ​ ​ 9,970,620 Total marketable securities ​ $ 40,344,143 ​ $ - ​ $ (180,268) ​ $ 40,163,875 ​ Marketable securities as of December 31, 2021 consisted of the following: ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ December 31, 2021 ​ Amortized Cost Unrealized Gains Unrealized Losses Fair Value Assets: ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Current: ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ U.S. Treasuries ​ $ 42,147,385 ​ $ - ​ $ (28,575) ​ $ 42,118,810 Government securities ​ ​ 19,218,057 ​ ​ - ​ ​ (13,689) ​ ​ 19,204,368 Commercial paper ​ ​ 12,992,165 ​ ​ 57 ​ ​ (4,197) ​ ​ 12,988,025 Total Current ​ ​ 74,357,607 ​ ​ 57 ​ ​ (46,461) ​ ​ 74,311,203 ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Non-current: ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ U.S. Treasuries ​ ​ 999,186 ​ ​ - ​ ​ (2,626) ​ ​ 996,560 Government securities ​ ​ - ​ ​ - ​ ​ - ​ ​ - Total Non-current ​ ​ 999,186 ​ ​ - ​ ​ (2,626) ​ ​ 996,560 Total marketable securities ​ $ 75,356,793 ​ $ 57 ​ $ (49,087) ​ $ 75,307,763

Fair Value Measurements (Tables

Fair Value Measurements (Tables)	6 Months Ended
	Jun. 30, 2022
Fair Value Measurements
Schedule of cash equivalents and marketable securities	​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Level 1 ​ ​ Level 2 ​ ​ Level 3 ​ ​ Total Assets: ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Cash equivalents ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Money market ​ $ 38,003,223 ​ $ - ​ $ - ​ $ 38,003,223 Commercial paper ​ ​ - ​ ​ 7,996,140 ​ ​ - ​ ​ 7,996,140 Total cash equivalents ​ ​ 38,003,223 ​ ​ 7,996,140 ​ ​ - ​ ​ 45,999,363 ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Marketable securities: ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ U.S. Treasuries ​ $ 21,622,575 ​ $ - ​ $ - ​ $ 21,622,575 Government securities ​ ​ - ​ ​ 8,570,680 ​ ​ - ​ ​ 8,570,680 Commercial paper ​ ​ - ​ ​ 9,970,620 ​ ​ - ​ ​ 9,970,620 Total marketable securities ​ ​ 21,622,575 ​ ​ 18,541,300 ​ ​ - ​ ​ 40,163,875 Total cash equivalents and marketable securities ​ $ 59,625,798 ​ $ 26,537,440 ​ $ - ​ $ 86,163,238 ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Level 1 ​ ​ Level 2 ​ ​ Level 3 ​ ​ Total Assets: ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Cash equivalents ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Money market ​ $ 33,961,344 ​ $ - ​ $ - ​ $ 33,961,344 Commercial paper ​ ​ - ​ ​ 2,000,000 ​ ​ - ​ ​ 2,000,000 Total cash equivalents ​ ​ 33,961,344 ​ ​ 2,000,000 ​ ​ - ​ ​ 35,961,344 ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Marketable securities: ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ U.S. Treasuries ​ $ 43,115,370 ​ $ - ​ $ - ​ $ 43,115,370 Government securities ​ ​ - ​ ​ 19,204,368 ​ ​ - ​ ​ 19,204,368 Commercial paper ​ ​ - ​ ​ 12,988,025 ​ ​ - ​ ​ 12,988,025 Total marketable securities ​ ​ 43,115,370 ​ ​ 32,192,393 ​ ​ - ​ ​ 75,307,763 Total cash equivalents and marketable securities ​ $ 77,076,714 ​ $ 34,192,393 ​ $ - ​ $ 111,269,107

Property and Equipment, net (Ta

Property and Equipment, net (Tables)	6 Months Ended
	Jun. 30, 2022
Property and Equipment, net
Schedule of property and equipment, net	​ ​ ​ ​ ​ ​ ​ ​ ​ June 30, December 31, ​ ​ 2022 ​ 2021 ​ ​ ​ ​ ​ ​ ​ Computer equipment ​ $ 318,793 ​ $ 281,666 Furniture and fixtures ​ 84,477 ​ 84,477 Lab equipment ​ ​ 650,727 ​ ​ 463,182 Leasehold improvements ​ ​ 207,492 ​ ​ 152,117 Total ​ 1,261,489 ​ 981,442 Accumulated depreciation ​ (276,482) ​ (174,219) Property and equipment, net ​ $ 985,007 ​ $ 807,223

Business Combination (Tables)

Business Combination (Tables)	6 Months Ended
	Jun. 30, 2022
Business Combination
Schedule of Assets Acquired and Liabilities Assumed at Fair Value	​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Preliminary Valuation ​ Measurement Period Adjustment ​ Final Valuation ​ Weighted Average Life Cash ​ $ 70,348 ​ $ - ​ $ 70,348 ​ ​ Other currents assets ​ ​ 225,790 ​ ​ - ​ ​ 225,790 ​ ​ Other long term assets ​ ​ 87,796 ​ ​ - ​ ​ 87,796 ​ ​ Property and equipment, net ​ ​ 727,539 ​ ​ - ​ ​ 727,539 ​ ​ Right of use assets ​ ​ 4,824,700 ​ ​ - ​ ​ 4,824,700 ​ ​ Intangible asset ​ ​ ​ ​ ​ - ​ ​ ​ ​ ​ Technology ​ ​ 439,000 ​ ​ - ​ ​ 439,000 ​ 15 years Goodwill ​ ​ 6,701,726 ​ ​ 11,295 ​ ​ 6,690,431 ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Total assets acquired ​ ​ 13,076,899 ​ ​ - ​ ​ 13,065,604 ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Accounts payable, accrued expenses and other liabilities ​ ​ 69,714 ​ ​ (11,295) ​ ​ 58,419 ​ ​ Deferred tax liabilities ​ ​ 307,485 ​ ​ - ​ ​ 307,485 ​ ​ Lease liabilities ​ ​ 4,824,700 ​ ​ - ​ ​ 4,824,700 ​ ​ Net assets acquired ​ $ 7,875,000 ​ $ - ​ $ 7,875,000 ​ ​

Accrued Expenses (Tables)

Accrued Expenses (Tables)	6 Months Ended
	Jun. 30, 2022
Accrued Expenses
Schedule of accrued expenses	​ ​ ​ ​ ​ ​ ​ ​ ​ June 30, December 31, ​ ​ 2022 ​ 2021 ​ ​ ​ ​ ​ ​ ​ Accrued professional services ​ $ 251,271 ​ $ 250,977 Accrued employee expenses ​ 1,591,656 ​ 2,917,282 Accrued contract research expenses ​ 335,658 ​ 585,416 Accrued other ​ ​ 48,102 ​ ​ 211,772 Total ​ $ 2,226,687 ​ $ 3,965,447

Common Stock (Tables)

Common Stock (Tables)	6 Months Ended
	Jun. 30, 2022
Common Stock.
Schedule of common stock for conversion of preferred stock, exercise of warrants and exercise of stock options	​ ​ ​ ​ ​ ​ ​ June 30, December 31, ​ ​ 2022 ​ 2021 ​ ​ ​ ​ ​ Exercise of common stock options 3,827,454 2,859,544 ​ 3,827,454 2,859,544

Net Loss Per Share Attributab_2

Net Loss Per Share Attributable to Common Stockholders (Tables)	6 Months Ended
	Jun. 30, 2022
Net Loss Per Share Attributable to Common Stockholders
Schedule of basic and diluted net loss per share attributable to common stockholders	​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Three Months Ended June 30, Six Months Ended June 30, ​ ​ 2022 2021 ​ 2022 2021 ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Numerator: ​ ​ ​ ​ Net loss ​ $ (11,527,303) ​ $ (7,987,665) ​ $ (24,423,677) ​ $ (14,217,316) Denominator - basic and diluted: ​ ​ ​ ​ Weighted-average common shares outstanding, basic and diluted ​ 26,386,343 ​ 4,954,553 ​ 26,372,787 ​ 4,952,352 Net loss per share - basic and diluted ​ $ (0.44) ​ $ (1.61) ​ $ (0.93) ​ $ (2.87)
Schedule of potentially dilutive securities that have been excluded from the calculation of diluted net loss per share	​ ​ ​ ​ ​ ​ ​ 2022 2021 ​ ​ ​ ​ ​ Options to purchase common stock 3,827,454 2,668,327 Total shares of common stock equivalents 3,827,454 2,668,327

Stock-Based Compensation (Table

Stock-Based Compensation (Tables)	6 Months Ended
	Jun. 30, 2022
Stock-Based Compensation
Schedule of assumptions in its application of the Black-Scholes option pricing model for grants	​ ​ ​ ​ ​ ​ ​ ​ Six Months Ended June 30, ​ 2022 2021 ​ ​ ​ ​ ​ Weighted-average risk-free interest rate ​ 1.35% - 3.31% ​ 1.04% - 1.71% Expected term (in years) ​ 5.00 - 10 years ​ 5.83 - 10 years Expected dividend yield ​ 0% ​ 0% Expected volatility ​ 65.24% - 78.12% ​ 68.92% - 80.99%
Summary of stock option activity	​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Weighted ​ ​ ​ ​ ​ ​ Weighted- ​ Average ​ ​ ​ ​ ​ ​ ​ Average ​ Remaining ​ ​ ​ ​ ​ Number of ​ Exercise Price ​ Contractual ​ Aggregate ​ ​ Options ​ per Share Term (in Years) ​ Intrinsic Value ​ ​ ​ Outstanding at of December 31, 2021 2,859,544 ​ $ 6.55 8.30 ​ Granted 1,067,410 ​ ​ 9.50 ​ ​ ​ Exercised (72,100) ​ ​ 3.02 ​ ​ ​ Cancelled (27,400) ​ ​ 6.58 ​ ​ ​ Outstanding at June 30, 2022 3,827,454 ​ $ 7.43 ​ 8.31 ​ $ 3,669,555 ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Vested and exercisable at June 30, 2022 1,539,603 ​ $ 4.59 7.33 ​ $ 2,820,514 Vested and expected to vest at June 30, 2022 ​ 3,827,454 ​ $ 7.43 8.31 ​ $ 3,669,555
Summary of recognized share-based compensation expense recognized	​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Three Months Ended June 30, ​ Six Months Ended June 30, ​ 2022 2021 2022 2021 ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Cost of revenue ​ $ 4,014 ​ $ 22,367 ​ $ 8,644 ​ $ 44,882 Research and development ​ 504,938 ​ 168,725 ​ 937,657 ​ 222,732 General and administrative ​ 543,469 ​ 159,917 ​ 1,003,770 ​ 265,620 Total ​ $ 1,052,421 ​ $ 351,009 ​ $ 1,950,071 ​ $ 533,234

Commitments and Contingencies (

Commitments and Contingencies (Tables)	6 Months Ended
	Jun. 30, 2022
Commitments and Contingencies.
Schedule of Maturities of the lease liabilities due	​ ​ ​ ​ ​ ​ Amount Remainder of 2022 ​ $ 331,740 2023 ​ 843,463 2024 ​ 732,546 2025 ​ 739,689 2026 ​ 761,877 Thereafter ​ 4,467,246 Total future lease payments ​ 7,876,561 Less: Imputed interest ​ (2,945,504) Total lease liabilities ​ $ 4,931,057 Current portion lease liability ​ $ 286,374 Lease liability, noncurrent ​ 4,644,683 Total lease liability ​ $ 4,931,057
Schedule of Quantitative information regarding the Company's leases	​ ​ ​ ​ ​ ​ ​ ​ ​ ​ June 30, June 30, ​ ​ 2022 ​ 2021 ​ Lease costs: ​ ​ ​ ​ ​ Operating lease cost ​ $ 527,413 ​ $ 68,502 Short-term lease cost ​ 164,373 ​ 117,352 Sublease income ​ (95,470) ​ — ​ Total lease costs ​ $ 596,316 ​ $ 185,854 Cash paid for amounts included in the measurement of lease liabilities: ​ ​ Operating cash flows from operating leases ​ $ 328,250 ​ $ 55,440 Operating cash flows from short-term leases ​ 164,373 ​ 117,352 ​ ​ $ 492,623 ​ $ 172,792 ​ Weighted-average remaining lease term - operating leases ​ 9.49 years ​ 4.83 years ​ Weighted-average discount rate - operating leases ​ 9.3% ​ 6.0% ​

Organization and Nature of Bu_2

Organization and Nature of Business (Details) - USD ($)	Aug. 03, 2021	Jun. 30, 2022	Dec. 31, 2021
Organization and Nature of Business
Convertible preferred stock, outstanding (in shares)	8,528,078
Shares issued upon conversion	11,939,281
Accumulated deficit		$ 83,697,065	$ 59,273,388
Class A Common Stock
Organization and Nature of Business
Shares issued	1,125,000
Convertible preferred stock, outstanding (in shares)	11,939,281
IPO
Organization and Nature of Business
Aggregate net proceeds	$ 120,318,750
Offering costs	$ 2,124,317
Convertible preferred stock, outstanding (in shares)	8,528,078
IPO | Class A Common Stock
Organization and Nature of Business
Shares issued	8,625,000

Marketable Securities (Details)

Marketable Securities (Details) - USD ($)	3 Months Ended		6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021	Dec. 31, 2021
Marketable Securities
Impairment on available-for-sale marketable securities	$ 0	$ 0	$ 0	$ 0
Realized gains or losses on marketable securities	0	$ 0	0	$ 0
Marketable securities, current
Marketable securities at amortized cost, current	40,344,143		40,344,143		$ 74,357,607
Marketable securities unrealized gains, current					57
Marketable securities unrealized losses, current	(180,268)		(180,268)		(46,461)
Marketable securities, current	40,163,875		40,163,875		74,311,203
Marketable securities, non-current
Marketable securities at amortized cost, non-current					999,186
Marketable securities unrealized losses, non-current					(2,626)
Marketable securities, non-current					996,560
Marketable securities
Marketable securities at amortized cost					75,356,793
Marketable securities unrealized gains					57
Marketable securities unrealized losses					(49,087)
Marketable securities					75,307,763
U.S. Treasuries
Marketable securities, current
Marketable securities at amortized cost, current	21,748,299		21,748,299		42,147,385
Marketable securities unrealized losses, current	(125,724)		(125,724)		(28,575)
Marketable securities, current	21,622,575		21,622,575		42,118,810
Marketable securities, non-current
Marketable securities at amortized cost, non-current					999,186
Marketable securities unrealized losses, non-current					(2,626)
Marketable securities, non-current					996,560
Government securities
Marketable securities, current
Marketable securities at amortized cost, current	8,600,549		8,600,549		19,218,057
Marketable securities unrealized losses, current	(29,869)		(29,869)		(13,689)
Marketable securities, current	8,570,680		8,570,680		19,204,368
Commerical paper
Marketable securities, current
Marketable securities at amortized cost, current	9,995,295		9,995,295		12,992,165
Marketable securities unrealized gains, current					57
Marketable securities unrealized losses, current	(24,675)		(24,675)		(4,197)
Marketable securities, current	$ 9,970,620		$ 9,970,620		$ 12,988,025

Fair Value Measurements (Detail

Fair Value Measurements (Details) - USD ($)	6 Months Ended
	Jun. 30, 2022	Dec. 31, 2021
Assets:
Financial assets classified as Level 3	$ 0
Financial liabilities classified as Level 3	0
Marketable securities		$ 75,307,763
Recurring
Assets:
Total cash equivalents	45,999,363	35,961,344
Total marketable securities	40,163,875	75,307,763
Total cash equivalents and marketable securities	86,163,238	111,269,107
Recurring | Money market
Assets:
Total cash equivalents	38,003,223	33,961,344
Recurring | Commerical paper
Assets:
Total cash equivalents	7,996,140	2,000,000
Total marketable securities	9,970,620	12,988,025
Recurring | U.S. Treasuries
Assets:
Total marketable securities	21,622,575	43,115,370
Recurring | Government securities
Assets:
Total marketable securities	8,570,680	19,204,368
Recurring | Level 1
Assets:
Total cash equivalents	38,003,223	33,961,344
Total marketable securities	21,622,575	43,115,370
Total cash equivalents and marketable securities	59,625,798	77,076,714
Recurring | Level 1 | Money market
Assets:
Total cash equivalents	38,003,223	33,961,344
Recurring | Level 1 | U.S. Treasuries
Assets:
Total marketable securities	21,622,575	43,115,370
Recurring | Level 2
Assets:
Total cash equivalents	7,996,140	2,000,000
Total marketable securities	18,541,300	32,192,393
Total cash equivalents and marketable securities	26,537,440	34,192,393
Recurring | Level 2 | Commerical paper
Assets:
Total cash equivalents	7,996,140	2,000,000
Total marketable securities	9,970,620	12,988,025
Recurring | Level 2 | Government securities
Assets:
Total marketable securities	$ 8,570,680	$ 19,204,368

Property and Equipment, net (De

Property and Equipment, net (Details) - USD ($)	Jun. 30, 2022	Dec. 31, 2021
Property and Equipment, net
Property and equipment, gross	$ 1,261,489	$ 981,442
Accumulated depreciation	(276,482)	(174,219)
Property and equipment, net	985,007	807,223
Computer equipment
Property and Equipment, net
Property and equipment, gross	318,793	281,666
Furniture and fixtures
Property and Equipment, net
Property and equipment, gross	84,477	84,477
Lab equipment
Property and Equipment, net
Property and equipment, gross	650,727	463,182
Leasehold improvements
Property and Equipment, net
Property and equipment, gross	$ 207,492	$ 152,117

Property and Equipment, net - D

Property and Equipment, net - Depreciation (Details) - USD ($)	3 Months Ended		6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021
Property and Equipment, net
Depreciation expense	$ 54,560	$ 9,807	$ 102,263	$ 18,674

Business Combination - Narrativ

Business Combination - Narrative (Details)		12 Months Ended
	Dec. 22, 2021 USD ($) agreement shares	Dec. 31, 2021 USD ($)
BioArkive Inc | Research and development
Business Acquisition [Line Items]
Amount of related party expenses		$ 4,548,780
BioArkive Inc
Business Acquisition [Line Items]
Market value of acquisition	$ 8,750,000
Number of lease obligations acquired | agreement	3
Shares issued | shares	379,635
Trading days for share price	30 days
Lock in period for shares issued	6 months
Shares issued discount due to lack of marketability	10%
Consideration transferred	$ 7,875,000

Business Combination - Assets A

Business Combination - Assets Acquired and Liabilities Assumed (Details) - USD ($)		6 Months Ended
	Dec. 22, 2021	Jun. 30, 2022	Dec. 31, 2021
Intangible asset
Goodwill		$ 6,690,431	$ 6,701,726
BioArkive Inc
Assets Acquired and Liabilities Assumed at Fair Value
Cash	$ 70,348	70,348
Other currents assets	225,790	225,790
Other long term assets	87,796	87,796
Property and equipment, net	727,539	727,539
Right of use assets	4,824,700	4,824,700
Intangible asset
Technology	439,000	439,000
Goodwill	6,701,726	6,690,431
Total assets acquired	13,076,899	13,065,604
Accounts payable, accrued expenses and other liabilities	69,714	58,419
Deferred tax liabilities	307,485	307,485
Lease liabilities	4,824,700	4,824,700
Net assets acquired	$ 7,875,000	7,875,000
Decrease in goodwill		11,295
Decrease in liabilities		$ (11,295)
Weighted Average Life, technology	15 years

Accrued Expenses (Details)

Accrued Expenses (Details) - USD ($)	Jun. 30, 2022	Dec. 31, 2021
Accrued Expenses
Accrued professional services	$ 251,271	$ 250,977
Accrued employee expenses	1,591,656	2,917,282
Accrued contract research expenses	335,658	585,416
Accrued other	48,102	211,772
Total	$ 2,226,687	$ 3,965,447

Preferred Stock - Series B (Det

Preferred Stock - Series B (Details) - USD ($)	2 Months Ended
	May 31, 2021	Aug. 03, 2021
Temporary Equity [Line Items]
Shares issued upon conversion		11,939,281
Temporary Equity, Shares Outstanding		8,528,078
Series B Preferred Stock Tranche Two
Temporary Equity [Line Items]
Convertible preferred stock, issued (in shares)	2,412,853
Gross proceeds from issuance of convertible stock	$ 24,799,786
Issuance costs	$ 10,935

Common Stock - Class A common s

Common Stock - Class A common stock (Details) - Class A Common Stock	6 Months Ended	12 Months Ended
	Jun. 30, 2022 Vote $ / shares shares	Dec. 31, 2021 Vote $ / shares shares
Class of Stock [Line Items]
Common stock, shares authorized (in shares)	200,000,000	200,000,000
Common stock, par value per share (in dollars per share) | $ / shares	$ 0.001	$ 0.001
Common stock, shares issued (in shares)	26,392,299	26,320,199
Common stock, shares outstanding (in shares)	26,392,299	26,320,199
Number of votes | Vote	1	1

Common Stock (Details)

Common Stock (Details) - shares	Jun. 30, 2022	Dec. 31, 2021
Class of Stock [Line Items]
Shares reserved for future issuance	3,827,454	2,859,544
Common stock options
Class of Stock [Line Items]
Shares reserved for future issuance	3,827,454	2,859,544

Common Stock - Class B common s

Common Stock - Class B common stock (Details) - Class B Common Stock	6 Months Ended	12 Months Ended
	Jun. 30, 2022 Vote $ / shares shares	Dec. 31, 2021 Vote $ / shares shares
Class of Stock [Line Items]
Common stock, shares authorized (in shares)	20,000,000	20,000,000
Common stock, par value per share (in dollars per share) | $ / shares	$ 0.001	$ 0.001
Common stock, shares issued (in shares)	0	0
Common stock, shares outstanding (in shares)	0	0
Number of votes | Vote	0	0

Common Stock - IPO (Details)

Common Stock - IPO (Details) - USD ($)	Aug. 03, 2021	Jun. 30, 2022	Dec. 31, 2021
Class of Stock [Line Items]
Convertible preferred stock, outstanding (in shares)	8,528,078
Preferred stock authorized (in shares)		10,000,000	10,000,000
Class A Common Stock
Class of Stock [Line Items]
Shares issued	1,125,000
Convertible preferred stock, outstanding (in shares)	11,939,281
Common stock, shares authorized (in shares)		200,000,000	200,000,000
Common stock, par value per share (in dollars per share)		$ 0.001	$ 0.001
Class B Common Stock
Class of Stock [Line Items]
Common stock, shares authorized (in shares)		20,000,000	20,000,000
Common stock, par value per share (in dollars per share)		$ 0.001	$ 0.001
IPO
Class of Stock [Line Items]
Proceeds from Stock issued	$ 120,318,750
Offering costs	$ 2,124,317
Convertible preferred stock, outstanding (in shares)	8,528,078
Preferred stock authorized (in shares)	10,000,000
IPO | Class A Common Stock
Class of Stock [Line Items]
Shares issued	8,625,000
Common stock, shares authorized (in shares)	200,000,000
IPO | Class B Common Stock
Class of Stock [Line Items]
Common stock, shares authorized (in shares)	20,000,000
Common stock, par value per share (in dollars per share)	$ 0.001

Net Loss Per Share Attributab_3

Net Loss Per Share Attributable to Common Stockholders - Basic and diluted net loss per share attributable to common stockholders (Details) - USD ($)	3 Months Ended				6 Months Ended
	Jun. 30, 2022	Mar. 31, 2022	Jun. 30, 2021	Mar. 31, 2021	Jun. 30, 2022	Jun. 30, 2021
Numerator:
Net loss	$ (11,527,303)	$ (12,896,374)	$ (7,987,665)	$ (6,229,651)	$ (24,423,677)	$ (14,217,316)
Denominator - basic and diluted:
Weighted-average common shares outstanding, basic	26,386,343		4,954,553		26,372,787	4,952,352
Weighted-average common shares outstanding, diluted	26,386,343		4,954,553		26,372,787	4,952,352
Net loss per share, basic	$ (0.44)		$ (1.61)		$ (0.93)	$ (2.87)
Net loss per share, diluted	$ (0.44)		$ (1.61)		$ (0.93)	$ (2.87)

Net Loss Per Share Attributab_4

Net Loss Per Share Attributable to Common Stockholders - Antidilutive effect (Details) - shares	6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Total shares of common stock equivalents	3,827,454	2,668,327
Common stock options
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Total shares of common stock equivalents	3,827,454	2,668,327

Stock-Based Compensation - Narr

Stock-Based Compensation - Narratives (Details) - USD ($)		3 Months Ended		6 Months Ended
	Jul. 23, 2021	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021	Dec. 31, 2021
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Stock-based compensation expense		$ 1,052,421	$ 351,009	$ 1,950,071	$ 533,234
Granted (in shares)				1,067,410
Grant date weighted average fair value				$ 9.50
Shares reserved for future issuance		3,827,454		3,827,454		2,859,544
Incentive Plan
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Vesting period				4 years
Option available for future grant		2,825,173		2,825,173
Stock-based compensation expense		$ 1,052,421	$ 351,009	$ 1,950,071	$ 533,234
Compensation expense remaining to be recognized		$ 12,585,048		$ 12,585,048
Compensation expense recognized over a weighted-average period				2 years 9 months 29 days
2021 ESPP | Class A Common Stock
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Granted (in shares)				0
Shares reserved for future issuance	250,000
Aggregate number of shares outstanding (as a percent)	1%
2021 ESPP | Maximum | Class A Common Stock
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Granted (in shares)	3,340,000
2021 Plan
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Shares reserved for future issuance		2,311,230		2,311,230
2021 Plan | Maximum
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Shares reserved for future issuance	2,590,000
Aggregate number of shares outstanding (as a percent)	4%
2021 Plan | Maximum | Class A Common Stock
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Granted (in shares)	15,350,000

Stock-Based Compensation - Assu

Stock-Based Compensation - Assumptions (Details)	6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Weighted-average risk-free interest rate, minimum	1.35%	1.04%
Weighted-average risk-free interest rate, maximum	3.31%	1.71%
Expected dividend yield	0%	0%
Expected volatility, minimum	65.24%	68.92%
Expected volatility, maximum	78.12%	80.99%
Minimum
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Expected term (in years)	5 years	5 years 9 months 29 days
Maximum
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Expected term (in years)	10 years	10 years

Stock-Based Compensation - stoc

Stock-Based Compensation - stock option activity (Details)	6 Months Ended	12 Months Ended
	Jun. 30, 2022 USD ($) $ / shares shares	Dec. 31, 2021 $ / shares shares
Number of options
Outstanding at the beginning (in shares) | shares	2,859,544
Granted (in shares) | shares	1,067,410
Exercised (in shares) | shares	(72,100)
Cancelled (in shares) | shares	(27,400)
Outstanding at the end (in shares) | shares	3,827,454	2,859,544
Vested and exercisable (in shares) | shares	1,539,603
Vested and expected to vest (in shares) | shares	3,827,454
Weighted Average Exercise Price per Share
Weighted Average Exercise Price per Share Outstanding at the beginning (in dollars per share) | $ / shares	$ 6.55
Weighted Average Exercise Price per Share Granted (in dollars per share) | $ / shares	9.50
Weighted Average Exercise Price per Share Exercised (in dollars per share) | $ / shares	3.02
Weighted Average Exercise Price per Share Cancelled (in dollars per share) | $ / shares	6.58
Weighted Average Exercise Price per Share Outstanding at the end (in dollars per share) | $ / shares	7.43	$ 6.55
Weighted Average Exercise Price per Share Vested and Exercisable (in dollars per share) | $ / shares	4.59
Weighted Average Exercise Price per Share Vested and Expected to Vest exercisable (in dollars per share) | $ / shares	$ 7.43
Weighted Average Remaining Contractual Contractual Term
Weighted Average Remaining Contractual Term (in years)		8 years 3 months 18 days
Weighted Average Remaining Contractual Term Repurchased (in Years)	8 years 3 months 21 days
Weighted Average Remaining Contractual Term, Vested and exercisable (in Years)	7 years 3 months 29 days
Weighted Average Remaining Contractual Term, Vested and expected to vest (in Years)	8 years 3 months 21 days
Aggregate Intrinsic Value
Aggregate Intrinsic Value Outstanding | $	$ 3,669,555
Aggregate Intrinsic Value Vested and exercisable | $	2,820,514
Aggregate Intrinsic Value Vested and expected to vest | $	$ 3,669,555

Stock-Based Compensation - Shar

Stock-Based Compensation - Share-based compensation expense (Details) - USD ($)	3 Months Ended		6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Share-based compensation expense	$ 1,052,421	$ 351,009	$ 1,950,071	$ 533,234
Cost of service
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Share-based compensation expense	4,014	22,367	8,644	44,882
Research and development
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Share-based compensation expense	504,938	168,725	937,657	222,732
General and administrative
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Share-based compensation expense	$ 543,469	$ 159,917	$ 1,003,770	$ 265,620

Commitments and Contingencies -

Commitments and Contingencies - Narratives (Details)	1 Months Ended	6 Months Ended
	Jan. 31, 2022 USD ($)	Jun. 30, 2022 USD ($)	Dec. 31, 2021 USD ($)	Dec. 22, 2021 USD ($) ft² agreement	Oct. 31, 2020 USD ($)
Lessee, Lease, Description [Line Items]
Notice period for termination of lease		1 month
Minimum lease payment due 2022		$ 331,740
Right of use asset		4,691,157	$ 5,324,198
Lease liability		4,931,057
Decrease in right-of-use asset	$ 347,739
Incremental borrowing rate	6%
BioArkive Inc
Lessee, Lease, Description [Line Items]
Right of use asset				$ 4,824,700
Lease liability				$ 4,824,700
Number of Leases Obligations Assumed | agreement				3
Lease Termination on April 30, 2032 [Member]
Lessee, Lease, Description [Line Items]
Area of Property Under Lease | ft²				38,613
Lease Termination on December 31, 2022 [Member]
Lessee, Lease, Description [Line Items]
Area of Property Under Lease | ft²				6,100
Lease Termination on March 31, 2024 [Member]
Lessee, Lease, Description [Line Items]
Area of Property Under Lease | ft²				4,760
Office Space In Cambridge, Massachusetts, New York, San Francisco, California [Member]
Lessee, Lease, Description [Line Items]
Minimum lease payment due 2022		$ 39,600
Office And Laboratory Space in San Diego California [Member]
Lessee, Lease, Description [Line Items]
Period of lease modification	20 months
2020 San Diego Lease
Lessee, Lease, Description [Line Items]
Lease term					67 months
Right of use asset					$ 637,863

Commitments and Contingencies_2

Commitments and Contingencies - Maturities of the lease liabilities due (Details) - USD ($)	Jun. 30, 2022	Dec. 31, 2021
Commitments and Contingencies.
Remainder of 2022	$ 331,740
2023	843,463
2024	732,546
2025	739,689
2026	761,877
Thereafter	4,467,246
Total future lease payments	7,876,561
Less: Imputed interest	(2,945,504)
Total lease liabilities	4,931,057
Current portion lease liability	286,374	$ 274,039
Lease liability, noncurrent	$ 4,644,683	$ 5,090,897

Commitments and Contingencies_3

Commitments and Contingencies - Lease cost and contract termination (Details) - USD ($)	6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021
Lease costs:
Operating lease cost	$ 527,413	$ 68,502
Short-term lease cost	164,373	117,352
Sublease income	(95,470)
Total lease costs	596,316	185,854
Cash paid for amounts included in the measurement of lease liabilities:
Operating cash flows from operating leases	328,250	55,440
Operating cash flows from short-term leases	164,373	117,352
Total lease Payment	$ 492,623	$ 172,792
Weighted-average remaining lease term - operating leases	9 years 5 months 26 days	4 years 9 months 29 days
Weighted-average discount rate - operating leases	9.30%	6%
Notice Period For Contract Termination	30 days