| Document and Entity Information - USD ($) | 12 Months Ended | ||
| Dec. 31, 2020 | Mar. 31, 2021 | Jun. 30, 2020 | |
| Document and Entity Information [Abstract] | |||
| Document Type | 10-K/A | ||
| Document Annual Report | true | ||
| Document Transition Report | false | ||
| Document Period End Date | Dec. 31, 2020 | ||
| Entity File Number | 001-39169 | ||
| Entity Registrant Name | Kiromic BioPharma, Inc. | ||
| Entity Incorporation, State or Country Code | DE | ||
| Entity Tax Identification Number | 46-4762913 | ||
| Entity Address, Address Line One | 7707 Fannin Street | ||
| Entity Address, Adress Line Two | Suite 140 | ||
| Entity Address, City or Town | Houston | ||
| Entity Address State Or Province | TX | ||
| Entity Address, Postal Zip Code | 77054 | ||
| City Area Code | 832 | ||
| Local Phone Number | 968-4888 | ||
| Title of 12(b) Security | Common Shares, par value $0.001 per share | ||
| Trading Symbol | KRBP | ||
| Security Exchange Name | NASDAQ | ||
| Entity Well-known Seasoned Issuer | No | ||
| Entity Voluntary Filers | No | ||
| Entity Current Reporting Status | Yes | ||
| Entity Interactive Data Current | Yes | ||
| Entity Filer Category | Non-accelerated Filer | ||
| Entity Small Business | true | ||
| Entity Emerging Growth Company | true | ||
| Entity Ex Transition Period | false | ||
| ICFR Auditor Attestation Flag | false | ||
| Entity Shell Company | false | ||
| Entity Public Float | $ 0 | ||
| Entity Common Stock, Shares Outstanding | 7,332,999 | ||
| Entity Central Index Key | 0001792581 | ||
| Current Fiscal Year End Date | --12-31 | ||
| Document Fiscal Year Focus | 2020 | ||
| Document Fiscal Period Focus | FY | ||
| Amendment Flag | false |
