Exhibit 99.2
FORM OF LETTER TO SHAREHOLDERS WHO ARE RECORD HOLDERS
ITERUM THERAPEUTICS PLC AND ITERUM THERAPEUTICS BERMUDA LIMITED
Subscription Rights to purchase 8,400 Units, each Unit consisting of
a 6.500% Exchangeable Senior Subordinated Note due 2025 in the original principal amount of $1,000, to be issued
by Iterum Therapeutics Bermuda Limited and guaranteed on an unsecured senior subordinated basis by Iterum
Therapeutics plc, Iterum Therapeutics International Limited, Iterum Therapeutics US Limited and Iterum
Therapeutics US Holding Limited,
and
50 Limited Recourse Royalty-Linked Subordinated Notes, to be issued by Iterum Therapeutics Bermuda Limited and
guaranteed on an unsecured senior subordinated basis by Iterum Therapeutics plc, Iterum Therapeutics
International Limited, Iterum Therapeutics US Limited and Iterum Therapeutics US Holding Limited
at a Subscription Price of $1,000 Per Unit
Distributed to Shareholders
of Iterum Therapeutics plc
[ ], 2020
Dear Shareholder:
Enclosed are materials relating to a rights offering (the “Rights Offering”) by Iterum Therapeutics plc, a company formed under the laws of Ireland (“we,” “us,” “our,” or the “Company”), and Iterum Therapeutics Bermuda Limited, a company formed under the laws of Bermuda (“Iterum Bermuda”), including a prospectus dated [ ], 2020 (the “Prospectus”). Please carefully review the Prospectus, which describes how you may participate in the Rights Offering. In the Rights Offering, we and Iterum Bermuda are distributing, at no charge to the holders of record as of [ ] [a.m./p.m.], New York City time, on [ ], 2020 (the “record date”) of our outstanding ordinary shares, nominal value $0.01 per share (the “ordinary shares”),non-transferable subscription rights (“Rights”) to purchase units to be issued by Iterum Bermuda.
You will be able to exercise your Rights to purchase units (“Units”), each consisting of (a) a 6.500% Exchangeable Senior Subordinated Note due 2025, to be issued by Iterum Bermuda in the original principal amount of $1,000.00 (each, an “Exchangeable Note”), fully and unconditionally guaranteed on an unsecured senior subordinated basis by us, Iterum Therapeutics International Limited, Iterum Therapeutics US Limited and Iterum Therapeutics US Holding Limited (collectively, the “Guarantors”), and (b) 50 Limited Recourse Royalty-Linked Notes, to be issued by Iterum Bermuda (each, a “Royalty-Linked Note”), fully and unconditionally guaranteed on an unsecured senior subordinated basis by the Guarantors. No fractional Rights or Units will be distributed or issued. Holders of Rights may only purchase whole Units in the Rights Offering.
As described in the Prospectus, you will receive one (1) Right for each outstanding ordinary share owned as of the record date. The Rights and Units are described in the Prospectus. Any prospective purchaser of Units pursuant to the exercise of the Rights should read the Prospectus, including, without limitation, the risk factors contained therein, prior to making any decision to participate in the Rights Offering.
The Rights may be exercised at any time during the subscription period, which will commence on [ ], 2020 and end at [ ] [a.m./p.m.], New York City time, on [ ], 2020 (the “Subscription Period”). The Rights will expire and will have no value unless exercised prior to the expiration of the Subscription Period.