Exhibit 23.1
Consent of Independent Registered Public Accounting Firm
We consent to the incorporation by reference in the Registration Statement (Form S-8) pertaining to the 2004 Equity Incentive Plan and 2004 Employee Stock Purchase Plan of Depomed, Inc. of our reports dated March 8, 2010, with respect to the financial statements and schedule of Depomed, Inc. included in its Annual Report (Form 10-K) for the year ended December 31, 2009, and the effectiveness of internal control over financial reporting of Depomed, Inc. filed with the Securities and Exchange Commission.
| /s/ Ernst & Young LLP |
| |
Palo Alto, California | |
May 21, 2010 | |