Shares
Value
Common
Stocks
–
84.6%
Communication
Services
–
2.1%
Telesat
Corp.*
............................................................
290,781
$
2,500,717
Energy
–
21.2%
Plains
GP
Holdings
LP,
Class
A*
..............................................
1,372,360
25,045,570
Health
Care
–
61.3%
Achieve
Life
Sciences,
Inc.*
.................................................
217,845
990,105
Akero
Therapeutics,
Inc.*
...................................................
212,477
5,367,169
Applied
Therapeutics,
Inc.*
..................................................
2,817,505
19,159,034
Ardelyx,
Inc.*
.............................................................
350,000
2,555,000
Athira
Pharma,
Inc.*
.......................................................
1,492,792
4,090,250
Avidity
Biosciences,
Inc.*
...................................................
125,000
3,190,000
Chinook
Therapeutics,
Inc.*
.................................................
25,000
9,750
Cybin,
Inc.*
..............................................................
500,000
206,750
Day
One
Biopharmaceuticals,
Inc.*
...........................................
175,018
2,891,297
Eiger
BioPharmaceuticals,
Inc.*
..............................................
90,000
450,000
Fulcrum
Therapeutics,
Inc.*
.................................................
465,000
4,389,600
Kura
Oncology,
Inc.*
.......................................................
80,000
1,706,400
Kymera
Therapeutics,
Inc.*
..................................................
30,515
1,226,703
Madrigal
Pharmaceuticals,
Inc.*
..............................................
23,294
6,220,430
Marinus
Pharmaceuticals,
Inc.*
..............................................
150,000
1,356,000
Mirum
Pharmaceuticals,
Inc.*
................................................
70,000
1,758,400
Phathom
Pharmaceuticals,
Inc.*
..............................................
521,935
5,542,950
Sutro
Biopharma,
Inc.*
.....................................................
120,000
678,000
Syndax
Pharmaceuticals,
Inc.*
...............................................
50,000
1,190,000
Trevi
Therapeutics,
Inc.*
....................................................
200,000
690,000
TScan
Therapeutics,
Inc.*
...................................................
1,046,916
8,312,513
X4
Pharmaceuticals,
Inc.*
...................................................
400,000
556,000
72,536,351
Total
Common
Stocks
(Cost
$77,040,901)
..........................................
100,082,638
Exchange-Traded
Funds
–
4.6%
Fixed
Income
Funds
–
4.6%
iShares
iBoxx
$
Investment
Grade
Corporate
Bond
ETF
...........................
4,456
485,348
iShares
MBS
ETF
.........................................................
22,400
2,070,208
Simplify
Enhanced
Income
ETF(a)
............................................
120,221
2,933,392
Total
Exchange-Traded
Funds
(Cost
$5,583,047)
....................................
5,488,948
Principal
Corporate
Bonds
–
2.8%
Communications
–
2.8%
Telesat
Canada
/
Telesat
LLC,
5.63%,
12/6/2026,
144A(b)
.........................
$
2,700,000
1,601,409
Telesat
Canada
/
Telesat
LLC,
6.50%,
10/15/2027,
144A(b)
........................
4,124,000
1,752,700
Total
Corporate
Bonds
(Cost
$3,927,083)
...........................................
3,354,109
Shares
Closed-End
Funds
–
1.3%
Equity
Funds
–
1.3%
Kayne
Anderson
Energy
Infrastructure
Fund
(Cost
$1,177,582)
.......................................................
147,033
1,471,800