Orchestra BioMed (OBIO) SC 13D Health Sciences Acquisitions Corp 2 / RTW INVESTMENTS ownership change

CUSIP No. G4411D 109 13D Page 11 of 11 Pages

EXHIBIT 1

AGREEMENT

Pursuant to Rule 13d-1(k)(1) under the Securities Exchange Act of 1934, the undersigned hereby agree that only one statement containing the information required by Schedule 13D need be filed with respect to the ownership by each of the undersigned of shares of stock of Health Sciences Acquisitions Corporation 2,

EXECUTED this 12^th day of October, 2022.

RTW INVESTMENTS, LP
By:	/s/ Roderick Wong
Name: Roderick Wong, M.D.
Title: Managing Partner
RTW MASTER FUND, LTD.
By:	/s/ Roderick Wong
Name: Roderick Wong, M.D.
Title: Director
RTW INNOVATION MASTER FUND, LTD.
By:	/s/ Roderick Wong
Name: Roderick Wong, M.D.
Title: Director
/s/ Roderick Wong
Roderick Wong, M.D.