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Exhibit 16.1
August 27, 2021
Securities and Exchange Commission
100 F Street, N.E.
Washington, DC 20549
Commissioners:
We have read the statements made by Humacyte, Inc. (formerly Alpha Healthcare Acquisition Corp.) under Item 4.01 of its Form 8-K dated August 27, 2021. We agree with the statements concerning our Firm in such Form 8-K; we are not in a position to agree or disagree with other statements of Humacyte, Inc. (formerly Alpha Healthcare Acquisition Corp.) contained therein.
Very truly yours,
/s/ Marcum llp
Marcum llp