Adagene (ADAG) F-3 Shelf registration (foreign)

Exhibit 107

Calculation of Filing Fee Tables

Form F-3

(Form Type)

Adagene Inc.

(Exact Name of Registrant as Specified in its Charter)

Not Applicable

(Translation of Registrant’s Name into English)

Table 1: Newly Registered and Carry Forward Securities

	Security Type		Security Class Title		Fee Calculation or Carry Forward Rule		Amount Registered	Proposed Maximum Offering Price Per Unit	Maximum Aggregate Offering Price(1)		Fee Rate		Amount of Registration Fee(2)			Carry Forward Form Type		Carry Forward File Number		Carry Forward Initial effective date		Filing Fee Previously Paid In Connection with Unsold Securities to be Carried Forward
Newly Registered Securities
Fees to Be Paid		Equity		Ordinary shares, par value $0.0001 per share(4)
Fees to Be Paid		Other		Warrants
Fees to Be Paid		Other		Units
Fees to Be Paid		Unallocated (Universal) Shelf		-		457(o)			$	200,000,000	$	0.0000927	$	18,540	(3)
Fees Previously Paid		-		-		-	-	-		-		-		-
Carry Forward Securities
Carry Forward Securities		-		-		-	-			-							-		-		-	-
		Total Offering Amounts							$	200,000,000			$	18,540
		Total Fees Previously Paid												-
		Total Fee Offsets												-
		Net Fee Due											$	18,540

(1) The registrant is hereby registering an indeterminate number of securities of each identified class as may from time to time be offered at unspecified prices or upon conversion, exchange or exercise of securities registered hereunder to the extent such securities are, by their terms, exercisable for, such securities. The maximum aggregate offering price of all securities covered by this registration statement will not exceed $200,000,000. The registrant has estimated the proposed maximum aggregate offering price solely for the purpose of calculating the registration fee pursuant to Rule 457(o) under the Securities Act of 1933, as amended (the “Securities Act”). The securities registered hereunder include securities that may be purchased by underwriters to cover over-allotments, if any. In addition, pursuant to Rule 416 under the Securities Act, the ordinary shares being registered hereunder include such indeterminate number of ordinary shares as may be issuable with respect to the shares being registered hereunder as a result of share subdivision or consolidation, share dividends, or similar transactions.

(2) The registration fee has been calculated pursuant to Rule 457(o) under the Securities Act on the basis of the maximum aggregate offering price of the securities listed.

(3) Paid herewith.

(4) Each American Depositary Share represents one and one quarter (1.25) of ordinary shares, par value $0.0001 per share. Ordinary shares may be in the form of American Depositary Shares. American Depositary Shares issuable on deposit of the ordinary shares registered hereby have been registered under the Registration Statement on Form F-6 (Registration No. 333-252543), which was filed with the Securities and Exchange Commission on January 29, 2021.