| Cover | Feb. 24, 2022 |
| Document Type | 8-K |
| Amendment Flag | false |
| Document Period End Date | Feb. 24, 2022 |
| Entity File Number | 001-39834 |
| Entity Registrant Name | Clene Inc. |
| Entity Central Index Key | 0001822791 |
| Entity Tax Identification Number | 85-2828339 |
| Entity Incorporation, State or Country Code | DE |
| Entity Address, Address Line One | 6550 South Millrock Drive |
| Entity Address, Address Line Two | Suite G50 |
| Entity Address, City or Town | Salt Lake City |
| Entity Address, State or Province | UT |
| Entity Address, Postal Zip Code | 84121 |
| City Area Code | 801 |
| Local Phone Number | 676-9695 |
| Written Communications | false |
| Soliciting Material | false |
| Pre-commencement Tender Offer | false |
| Pre-commencement Issuer Tender Offer | false |
| Entity Emerging Growth Company | true |
| Elected Not To Use the Extended Transition Period | false |
| Common Stock, par value US$0.0001 per share | |
| Title of 12(b) Security | Common Stock, $0.0001 par value |
| Trading Symbol | CLNN |
| Security Exchange Name | NASDAQ |
| Warrants, to acquire one-half of one share of Common Stock for $11.50 per share | |
| Title of 12(b) Security | Warrants, to acquire one-half of one share of Common Stock for $11.50 per share |
| Trading Symbol | CLNNW |
| Security Exchange Name | NASDAQ |
