Clene (CLNN) SC 13G Clene / Vivo Opportunity Fund ownership change

EXHIBIT 99.1

Joint Filing Agreement

The undersigned acknowledge and agree that the foregoing statement on Schedule 13G is filed on behalf of each of the undersigned and that all subsequent amendments to this statement on Schedule 13G shall be filed on behalf of each of the undersigned without the necessity of filing additional joint filing statements. The undersigned acknowledge that each shall be responsible for the timely filing of such amendments, and for the completeness and accuracy of the information concerning him, her or it contained herein, but shall not be responsible for the completeness and accuracy of the information concerning the other entities or persons, except to the extent that he, she or it knows or has reason to believe that such information is inaccurate.

Date: June 28, 2023

VIVO OPPORTUNITY FUND HOLDINGS, L.P,
By:	Vivo Opportunity, LLC
Its:	General Partner
/s/ Gaurav Aggarwal
Name:	Gaurav Aggarwal
Title:	Managing Member
VIVO OPPORTUNITY, LLC
/s/ Gaurav Aggarwal
Name:	Gaurav Aggarwal
Title:	Managing Member