| Document And Entity Information | May 29, 2024 |
| Document Information [Line Items] | |
| Entity, Registrant Name | CLENE INC. |
| Current Fiscal Year End Date | --12-31 |
| Document, Type | 8-K |
| Document, Period End Date | May 29, 2024 |
| Entity, Incorporation, State or Country Code | DE |
| Entity, File Number | 001-39834 |
| Entity, Tax Identification Number | 85-2828339 |
| Entity, Address, Address Line One | 6550 South Millrock Drive, Suite G50 |
| Entity, Address, City or Town | Salt Lake City |
| Entity, Address, State or Province | UT |
| Entity, Address, Postal Zip Code | 84121 |
| City Area Code | 801 |
| Local Phone Number | 676-9695 |
| Written Communications | false |
| Soliciting Material | false |
| Pre-commencement Tender Offer | false |
| Pre-commencement Issuer Tender Offer | false |
| Entity, Emerging Growth Company | false |
| Amendment Flag | false |
| Entity, Central Index Key | 0001822791 |
| CommonStock00001ParValue Custom [Member] | |
| Document Information [Line Items] | |
| Title of 12(b) Security | Common Stock, $0.0001 par value |
| Trading Symbol | CLNN |
| Security Exchange Name | NASDAQ |
| WarrantsToAcquireOnehalfOfOneShareOfCommonStockFor1150PerShare Custom [Member] | |
| Document Information [Line Items] | |
| Title of 12(b) Security | Warrants, to acquire one-half of one share of Common Stock for $11.50 per share |
| Trading Symbol | CLNNW |
| Security Exchange Name | NASDAQ |
