Clene (CLNN) S-3 Shelf registration

Exhibit 107

Calculation of Filing Fee Tables

Form S-3

(Form Type)

Clene Inc.

(Exact Name of Registrant as Specified in its Charter)

Table 1: Newly Registered and Carry Forward Securities

Security Type

Security Class Title

Fee Calculation or Carry Forward Rule

Amount Registered

Proposed Maximum Offering Price Per Unit

Maximum Aggregate Offering Price

Fee Rate

Amount of Registration Fee

Carry Forward Form Type

Carry Forward File Number

Carry Forward Initial Effective Date

Filing Fee Previously Paid In Connection with Unsold Securities to be Carried Forward

Newly Registered Securities

Fees to Be Paid

Equity

Common Stock, par value $0.0001 per share

Equity

Preferred Stock, par value $0.0001 per share

Debt

Debt Securities

Other

Warrants

Other

Units

Unallocated (Universal Shelf)

457(o)

(1)

(2)

$

175,000,000

$92.70 per $1,000,000

$

16,222.50

Fees Previously Paid

N/A

N/A

N/A

N/A

N/A

N/A

N/A

Carry Forward Securities

Carry Forward Securities

N/A

N/A

N/A

N/A

N/A

N/A

N/A

N/A

N/A

N/A

Total Offering Amounts

175,000,000

$

16,222.50

Total Fees Previously Paid

—

Total Fee Offsets

—

Net Fee Due

$

16,222.50

(1)

There are being registered hereunder, an indeterminate number or amount, as the case may be, of common stock, preferred stock, debt securities, warrants to purchase common stock, and units as permitted by General Instruction II.D, as may be offered by the registrant from time to time, which together shall have an aggregate initial offering price not to exceed $175,000,000. Any securities registered hereunder may be sold separately or as units with other securities registered hereunder. The securities registered hereunder also include an indeterminate number of securities as may be issued upon conversion or exercise of or exchange for preferred stock or debt securities that provide for conversion or exchange, upon exercise of warrants, or pursuant to the anti-dilution provisions of any of such securities. In addition, pursuant to Rule 416 under the Securities Act of 1933, as amended, or the Securities Act, this registration statement also covers any additional securities that may be offered or issued in connection with any stock splits, stock dividends or similar transactions.

(2)

Estimated solely for purposes of computing the registration fee. The proposed maximum offering price per unit and proposed maximum aggregate offering price for each type of security will be determined from time to time by the registrant in connection with the issuance by the registrant of the securities registered hereunder.