Document And Entity Information
Document And Entity Information - shares | 6 Months Ended | |
Jun. 30, 2022 | Aug. 05, 2022 | |
Document Information [Line Items] | ||
Document Type | 10-Q | |
Amendment Flag | false | |
Document Quarterly Report | true | |
Document Transition Report | false | |
Document Period End Date | Jun. 30, 2022 | |
Document Fiscal Year Focus | 2022 | |
Entity File Number | 001-39787 | |
Entity Registrant Name | BIOATLA, INC. | |
Entity Incorporation, State or Country Code | DE | |
Entity Tax Identification Number | 85-1922320 | |
Entity Address, Address Line One | 11085 Torreyana Road | |
Entity Address, City or Town | San Diego | |
Entity Address, State or Province | CA | |
Entity Address, Postal Zip Code | 92121 | |
City Area Code | 858 | |
Local Phone Number | 558-0708 | |
Title of 12(b) Security | Common Stock, $0.0001 par value per share | |
Trading Symbol | BCAB | |
Security Exchange Name | NASDAQ | |
Entity Current Reporting Status | Yes | |
Entity Interactive Data Current | Yes | |
Entity Filer Category | Large Accelerated Filer | |
Entity Small Business | false | |
Entity Emerging Growth Company | false | |
Entity Shell Company | false | |
Entity Central Index Key | 0001826892 | |
Current Fiscal Year End Date | --12-31 | |
Document Fiscal Period Focus | Q2 | |
Common Class B | ||
Document Information [Line Items] | ||
Entity Common Stock, Shares Outstanding | 1,211,959 | |
Common Stock | ||
Document Information [Line Items] | ||
Entity Common Stock, Shares Outstanding | 36,304,142 |
Condensed Consolidated Balance
Condensed Consolidated Balance Sheets - USD ($) $ in Thousands | Jun. 30, 2022 | Dec. 31, 2021 |
Current assets: | ||
Cash and cash equivalents | $ 202,290 | $ 244,979 |
Prepaid expenses and other current assets | 4,907 | 2,313 |
Total current assets | 207,197 | 247,292 |
Property and equipment, net | 3,277 | 3,676 |
Operating lease right-of-use asset, net | 2,867 | 3,300 |
Other assets | 155 | 154 |
Total assets | 213,496 | 254,422 |
Current liabilities: | ||
Accounts payable and accrued expenses | 24,032 | 18,424 |
Operating lease liabilities | 1,475 | 1,389 |
Total current liabilities | 25,507 | 19,813 |
Operating lease liabilities, less current portion | 3,231 | 3,982 |
Liability to licensor | 19,806 | 19,806 |
Total liabilities | 48,544 | 43,601 |
Commitments and contingencies (Note 6) | ||
Stockholders’ equity: | ||
Preferred stock, $0.0001 par value; 200,000,000 shares authorized at June 30, 2022 and December 31, 2021; 0 shares issued and outstanding at June 30, 2022 and December 31, 2021 | 0 | 0 |
Common stock value | 4 | 4 |
Additional paid-in capital | 404,427 | 397,136 |
Accumulated deficit | (239,479) | (186,319) |
Total stockholders’ equity | 164,952 | 210,821 |
Total liabilities and stockholders’ equity | 213,496 | 254,422 |
Class B Common Stock | ||
Stockholders’ equity: | ||
Common stock value |
Condensed Consolidated Balanc_2
Condensed Consolidated Balance Sheets (Parenthetical) - $ / shares | Jun. 30, 2022 | Dec. 31, 2021 |
Preferred stock, par value (in dollars per share) | $ 0.0001 | $ 0.0001 |
Preferred stock, shares authorized (in shares) | 200,000,000 | 200,000,000 |
Preferred stock, shares issued (in shares) | 0 | 0 |
Preferred stock, shares outstanding (in shares) | 0 | 0 |
Common stock, par value (in dollars per share) | $ 0.0001 | $ 0.0001 |
Common stock, shares authorized (in shares) | 350,000,000 | 350,000,000 |
Common stock, shares issued (in shares) | 35,993,458 | 35,799,233 |
Common stock, shares outstanding (in shares) | 35,993,458 | 35,799,233 |
Class B Common Stock | ||
Common stock, par value (in dollars per share) | $ 0.0001 | $ 0.0001 |
Common stock, shares authorized (in shares) | 15,368,569 | 15,368,569 |
Common stock, shares issued (in shares) | 1,492,059 | 1,492,059 |
Common stock, shares outstanding (in shares) | 1,492,059 | 1,492,059 |
Unaudited Condensed Consolidate
Unaudited Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands | 3 Months Ended | 6 Months Ended | ||
Jun. 30, 2022 | Jun. 30, 2021 | Jun. 30, 2022 | Jun. 30, 2021 | |
Income Statement [Abstract] | ||||
Collaboration and other revenue | $ 250 | $ 250 | ||
Operating expenses: | ||||
Research and development expense | 20,711 | 14,850 | 37,634 | 25,273 |
General and administrative expense | 8,344 | 15,860 | 15,767 | 24,234 |
Total operating expenses | 29,055 | 30,710 | 53,401 | 49,507 |
Loss from operations | (29,055) | (30,460) | (53,401) | (49,257) |
Other income (expense): | ||||
Interest income | 146 | 80 | 231 | 178 |
Interest expense | (1) | (3) | ||
Other income | 3 | 10 | ||
Total other income (expense) | 149 | 79 | 241 | 175 |
Consolidated net loss and comprehensive loss | $ (28,906) | $ (30,381) | $ (53,160) | $ (49,082) |
Net loss per common share, basic | $ (0.77) | $ (0.90) | $ (1.42) | $ (1.46) |
Net loss per common share, diluted | $ (0.77) | $ (0.90) | $ (1.42) | $ (1.46) |
Weighted-average shares of common stock outstanding, basic | 37,420,327 | 33,678,893 | 37,371,614 | 33,671,298 |
Weighted-average shares of common stock outstanding, diluted | 37,420,327 | 33,678,893 | 37,371,614 | 33,671,298 |
Unaudited Condensed Consolida_2
Unaudited Condensed Consolidated Statement of Stockholders' Equity - USD ($) $ in Thousands | Total | Class B Common Stock | Common Stock | Additional Paid-In Capital | Accumulate Deficit |
Beginning balance at Dec. 31, 2020 | $ 209,974 | $ 3 | $ 300,888 | $ (90,917) | |
Beginning balance, share at Dec. 31, 2020 | 1,492,059 | 32,171,560 | |||
Stock-based compensation expense | 16,941 | 16,941 | |||
Issuance of common stock under equity incentive plans, share | 138,461 | ||||
Issuance of common stock for Employee Stock Purchase Plan | 190 | 190 | |||
Issuance of common stock for Employee Stock Purchase Plan, shares | 5,280 | ||||
Net loss | (49,082) | (49,082) | |||
Ending balance at Jun. 30, 2021 | 178,023 | $ 3 | 318,019 | (139,999) | |
Ending balance, share at Jun. 30, 2021 | 1,492,059 | 32,315,301 | |||
Beginning balance at Mar. 31, 2021 | 195,916 | $ 3 | 305,531 | (109,618) | |
Beginning balance, share at Mar. 31, 2021 | 1,492,059 | 32,171,560 | |||
Stock-based compensation expense | 12,298 | 12,298 | |||
Issuance of common stock under equity incentive plans, share | 138,461 | ||||
Issuance of common stock for Employee Stock Purchase Plan | 190 | 190 | |||
Issuance of common stock for Employee Stock Purchase Plan, shares | 5,280 | ||||
Net loss | (30,381) | (30,381) | |||
Ending balance at Jun. 30, 2021 | 178,023 | $ 3 | 318,019 | (139,999) | |
Ending balance, share at Jun. 30, 2021 | 1,492,059 | 32,315,301 | |||
Beginning balance at Dec. 31, 2021 | 210,821 | $ 4 | 397,136 | (186,319) | |
Beginning balance, share at Dec. 31, 2021 | 1,492,059 | 35,799,233 | |||
Stock-based compensation expense | 7,474 | 7,474 | |||
Issuance of common stock under equity incentive plans, share | 184,743 | ||||
Issuance of common stock for Employee Stock Purchase Plan | 19 | 19 | |||
Issuance of common stock for Employee Stock Purchase Plan, shares | 9,482 | ||||
Taxes related to net share settlement of equity awards | (202) | (202) | |||
Net loss | (53,160) | (53,160) | |||
Ending balance at Jun. 30, 2022 | 164,952 | $ 4 | 404,427 | (239,479) | |
Ending balance, share at Jun. 30, 2022 | 1,492,059 | 35,993,458 | |||
Beginning balance at Mar. 31, 2022 | 190,053 | $ 4 | 400,622 | (210,573) | |
Beginning balance, share at Mar. 31, 2022 | 1,492,059 | 35,891,284 | |||
Stock-based compensation expense | 3,842 | 3,842 | |||
Issuance of common stock under equity incentive plans, share | 92,692 | ||||
Issuance of common stock for Employee Stock Purchase Plan | 19 | 19 | |||
Issuance of common stock for Employee Stock Purchase Plan, shares | 9,482 | ||||
Taxes related to net share settlement of equity awards | (56) | (56) | |||
Net loss | (28,906) | (28,906) | |||
Ending balance at Jun. 30, 2022 | $ 164,952 | $ 4 | $ 404,427 | $ (239,479) | |
Ending balance, share at Jun. 30, 2022 | 1,492,059 | 35,993,458 |
Unaudited Condensed Consolida_3
Unaudited Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands | 6 Months Ended | |
Jun. 30, 2022 | Jun. 30, 2021 | |
Cash flows from operating activities | ||
Net loss | $ (53,160) | $ (49,082) |
Adjustments to reconcile net loss to net cash used in operating activities: | ||
Depreciation and amortization | 601 | 636 |
Loss on disposal of property and equipment | 6 | 4 |
Stock-based compensation | 7,474 | 16,941 |
Accrued interest | 3 | |
Changes in operating assets and liabilities: | ||
Prepaid expenses and other assets | (2,595) | (2,646) |
Accounts payable and accrued expenses | 5,849 | 5,716 |
Right-of-use assets and lease liabilities, net | (232) | (111) |
Net cash used in operating activities | (42,057) | (28,539) |
Cash flows from investing activities | ||
Purchases of property and equipment | (179) | (736) |
Proceeds from sale of property and equipment | 3 | |
Net cash used in investing activities | (176) | (736) |
Cash flows from financing activities | ||
Payment of initial public offering costs | (1,911) | |
Proceeds from issuance of common stock under Employee Stock Purchase Plan | 19 | 190 |
Payments for taxes related to net settlement of equity awards | (475) | |
Net cash used in financing activities | (456) | (1,721) |
Net decrease in cash and cash equivalents | (42,689) | (30,996) |
Cash and cash equivalents, beginning of period | 244,979 | 238,605 |
Cash and cash equivalents, end of period | 202,290 | 207,609 |
Supplemental disclosure of non-cash investing and financing activities | ||
Property and equipment additions included in accounts payable and accrued expenses | 33 | 42 |
Tax related to net settlement of equity awards included in accounts payable and accrued expenses | $ 18 |
Organization and Summary of Sig
Organization and Summary of Significant Accounting Policies | 6 Months Ended |
Jun. 30, 2022 | |
Accounting Policies [Abstract] | |
Organization and Summary of Significant Accounting Policies | 1. Organization and Summary of Significant Accounting Policies Organization BioAtla, LLC was formed in Delaware in March 2007 and, after undergoing two separate reorganizations in 2019 and in 2020, was converted to a Delaware corporation in July 2020 and was renamed BioAtla, Inc. (the “Company”). The Company has a proprietary platform for creating biologics, including its conditionally active biologics (“CAB” or “CABs”). CABs have been designed to be active only under certain conditions found in diseased tissue, while remaining inactive in normal tissue. The Company is currently in clinical development of its two lead CAB antibody drug conjugates (“CAB ADC”) targeting AXL and ROR2 receptors, and its CAB immune-oncology antibody targeting CTLA-4. Basis of Presentation and Principles of Consolidation Prior to the reorganization in July 2020 (or "Corporate Reorganization"), the consolidated financial statements included the accounts of BioAtla, LLC and those of its majority owned subsidiary Himalaya Therapeutics SEZC that had no material operations. Himalaya Therapeutics SEZC also had a wholly owned subsidiary, Himalaya Therapeutics HK Limited that had no material operations. All intercompany balances were eliminated in consolidation. In connection with the Corporate Reorganization, Himalaya Therapeutics SEZC and Himalaya Therapeutics HK Limited were deconsolidated without material impact to the consolidated financial statements. Subsequent to the Corporate Reorganization, BioAtla, Inc. became a single legal entity with no consolidated variable interest entities ("VIEs") or subsidiaries. The unaudited condensed consolidated financial statements as of June 30, 2022, and for the three and six months ended June 30, 2022 and 2021, have been prepared in accordance with the rules and regulations of the Securities and Exchange Commission (“SEC”), and with accounting principles generally accepted in the United States (“GAAP”) applicable to interim financial statements. These unaudited condensed consolidated financial statements have been prepared on the same basis as the audited financial statements and include all adjustments, consisting of only normal recurring accruals, which in the opinion of management are necessary to present fairly the Company’s financial position as of the interim date and results of operations for the interim periods presented. Interim results are not necessarily indicative of results for a full year or future periods. These unaudited condensed consolidated financial statements should be read in conjunction with the Company’s audited financial statements for the year ended December 31, 2021 , included in its Annual Report on Form 10-K filed with the SEC on February 28, 2022. Liquidity and Going Concern The Company has incurred cumulative operating losses and negative cash flows from operations since its inception and expects to continue to incur significant expenses and operating losses for the foreseeable future as it continues the development of its product candidates. As of June 30, 2022, the Company had an accumulated deficit of $ 239.5 million . The Company plans to continue to fund its losses from operations and capital funding needs through public or private equity or debt financings or other sources. If the Company is not able to secure adequate additional funding, the Company may be forced to make reductions in spending, extend payment terms with suppliers, liquidate assets where possible, or suspend or curtail planned programs. Any of these actions could materially harm the Company’s business, results of operations and future prospects. Management is required to perform a two-step analysis of the Company’s ability to continue as a going concern. Management must first evaluate whether there are conditions and events that raise substantial doubt about the Company’s ability to continue as a going concern (Step 1). If management concludes that substantial doubt is raised, management is also required to consider whether its plans alleviate that doubt (Step 2). Management’s assessment included the preparation of cash flow forecasts resulting in management’s conclusion that there is not substantial doubt about the Company’s ability to continue as a going concern as its current cash and cash equivalents will be sufficient to fund the Company’s operations for a period of at least one year from the issuance date of these unaudited condensed consolidated financial statements. Use of Estimates The preparation of the Company’s condensed consolidated financial statements requires it to make estimates and assumptions that impact the reported amounts of assets, liabilities, revenues and expenses and the disclosure of contingent assets and liabilities in the Company’s condensed consolidated financial statements and accompanying notes. The most significant estimates in the Company’s condensed consolidated financial statements relate to revenue recognition, accruals for research and development costs, and equity-based compensation. These estimates and assumptions are based on current facts, historical experience and various other factors believed to be reasonable under the circumstances, the results of which form the basis for making judgments about the carrying values of assets and liabilities and the recording of revenue and expenses that are not readily apparent from other sources. Actual results may differ materially and adversely from these estimates. To the extent there are material differences between the estimates and actual results, the Company’s future results of operations will be affected. Concentrations of Risk Financial instruments that potentially subject the Company to a significant concentration of credit risk consist primarily of cash and cash equivalents. The Company maintains deposits in federally insured financial institutions in excess of federally insured limits. The Company has not experienced any losses in such accounts and management believes that the Company is not exposed to significant credit risk due to the financial position of the depository institutions in which those deposits are held. Stock-Based Compensation Stock-based compensation expense represents the grant date fair value of equity awards, consisting of stock options, restricted stock units (“RSUs”) and employee stock purchase plan rights, over the requisite service period of the awards (usually the vesting period) on a straight-line basis. The Company estimates the fair value of stock option grants and employee stock purchase plan rights using the Black-Scholes option pricing model. Prior to the Company’s IPO, the fair value of RSUs was based on the estimated fair value of the underlying common stock on the date of grant and, subsequent to the Company’s IPO, the fair value is based on the closing sales price of the Company’s common stock on the date of grant. Equity award forfeitures are recognized as they occur. Leases The Company determines if an arrangement is a lease at inception. An arrangement is or contains a lease if it conveys the right to control the use of an identified asset for a period of time in exchange for consideration. If a lease is identified, classification is determined at lease commencement. Operating lease liabilities are recognized at the present value of the future lease payments at the lease commencement date. The Company’s leases do not provide an implicit interest rate and therefore the Company estimates its incremental borrowing rate to discount lease payments. The incremental borrowing rate reflects the interest rate that the Company would have to pay to borrow on a collateralized basis an amount equal to the lease payments in a similar economic environment over a similar term. Operating lease right-of-use (“ROU”) assets are based on the corresponding lease liability adjusted for any lease payments made at or before commencement, initial direct costs, and lease incentives. Renewals or early terminations are not accounted for unless the Company is reasonably certain to exercise these options. Operating lease expense is recognized and the ROU asset is amortized on a straight-line basis over the lease term. Variable lease costs are not included in the calculation of the ROU asset and the related lease liability and are recognized as incurred. The Company has a single lease agreement with lease and non-lease components, which are accounted for as a single lease component. Payments for short-term leases, defined as leases with a term of twelve months or less, are expensed on a straight-line basis over the lease term. The Company does not currently have any short-term leases. Operating leases are included in operating lease right-of-use assets, operating lease liabilities, and operating lease liabilities, non-current on the Company’s consolidated balance sheets. The Company does not have any finance leases. Comprehensive Loss Comprehensive loss is defined as a change in equity during a period from transactions and other events and circumstances from non-owner sources. There have been no items qualifying as other comprehensive loss and, therefore, for all periods presented, the Company’s comprehensive loss was the same as its reported net loss. Net Loss Per Share Basic net loss per common share is computed by dividing the net loss by the weighted-average number of common shares outstanding for the period, without consideration for potentially dilutive securities. Diluted net loss per share is computed by dividing the net loss by the weighted-average number of common shares and dilutive common stock equivalents outstanding for the period determined using the treasury-stock method. Dilutive common stock equivalents are comprised of RSUs, common stock options outstanding under the Company’s stock option plan, and contingently issuable shares under the Company's ESPP plan. Potentially dilutive securities not included in the calculation of diluted net loss per share because to do so would be anti-dilutive are as follows (in common stock equivalents): Six Months Ended 2022 2021 Common stock warrants — 717,674 Common stock options 2,727,336 850,149 Restricted stock units 739,959 1,781,576 ESPP shares 41,292 — Total 3,508,587 3,349,399 Recent Accounting Pronouncements There were no new accounting standards that had a material impact on the Company’s consolidated financial statements during the three or six months ended June 30, 2022, and there were no other new accounting standards or pronouncements that were issued but not yet effective as of June 30, 2022 that the Company expects to have a material impact on its consolidated financial statements. |
Balance Sheet Details
Balance Sheet Details | 6 Months Ended |
Jun. 30, 2022 | |
Balance Sheet Related Disclosures [Abstract] | |
Balance Sheet Details | 2. Balance Sheet Details Prepaid expenses and other current assets consist of the following (in thousands): June 30, December 31, Prepaid research and development $ 2,739 $ 1,811 Prepaid insurance 1,471 — Other prepaid expenses and current assets 697 502 Total $ 4,907 $ 2,313 Property and equipment consist of the following (in thousands): Useful life June 30, December 31, Furniture, fixtures and office equipment 3 - 7 $ 2,172 $ 2,123 Laboratory equipment 5 2,265 2,123 Leasehold improvements 2 - 3 3,687 3,687 8,124 7,933 Less accumulated depreciation and amortization ( 4,847 ) ( 4,257 ) Total $ 3,277 $ 3,676 Accounts payable and accrued expenses consist of the following (in thousands): June 30, December 31, Accounts payable $ 4,822 $ 1,179 Accrued compensation 1,833 2,671 Accrued research and development 15,598 13,501 Other accrued expenses 1,779 1,073 Total $ 24,032 $ 18,424 |
Fair Value Measurements
Fair Value Measurements | 6 Months Ended |
Jun. 30, 2022 | |
Fair Value Disclosures [Abstract] | |
Fair Value Measurements | 3. Fair Value Measurements The carrying amounts of the Company’s current financial assets and current financial liabilities are considered to be representative of their respective fair values because of the short-term nature of those instruments. As of June 30, 2022 and December 31, 2021 , the Company had no financial assets or liabilities measured at fair value on a recurring basis. The accounting guidance defines fair value, establishes a consistent framework for measuring fair value and expands disclosure for each major asset and liability category measured at fair value on either a recurring or non-recurring basis. Fair value is defined as an exit price, representing the amount that would be received to sell an asset or paid to transfer a liability in an orderly transaction between market participants. As such, fair value is a market-based measurement that should be determined based on assumptions that market participants would use in pricing an asset or liability. As a basis for considering such assumptions, the accounting guidance establishes a three-tier fair value hierarchy, which prioritizes the inputs used in measuring fair value as follows: Level 1: Observable inputs such as quoted prices in active markets. Level 2: Inputs, other than the quoted prices in active markets that are observable either directly or indirectly. Level 3: Unobservable inputs in which there is little or no market data, which require the reporting entity to develop its own assumptions. |
Debt
Debt | 6 Months Ended |
Jun. 30, 2022 | |
Debt Disclosure [Abstract] | |
Debt | 4. Debt The Company did no t have any outstanding debt as of June 30, 2022 or December 31, 2021. As of June 30, 2021, the Company had $ 0.7 million outstanding under a promissory note issued pursuant to the Paycheck Protection Program (“PPP”) of the CARES Act. The loan was subsequently forgiven in July 2021 and recognized as other income on the Company's Statement of Operations. For the three and six months ended June 30, 2021 , the Company recognized interest expense related to its outstanding debt of $ 1,000 and $ 3,000 , respectively. |
Leases
Leases | 6 Months Ended |
Jun. 30, 2022 | |
Leases [Abstract] | |
Leases | 5. Leases The Company has a single operating lease for its corporate headquarters and laboratory space in San Diego, California. The lease expires in July 2025 and the Company has an option to extend the term of the lease for an additional five years . Additionally, the lease includes certain rent abatement, rent escalations, tenant improvement allowances and additional charges for common area maintenance and other costs. The components of lease expense included in the Company’s condensed consolidated statements of operations include (in thousands): Three Months Ended June 30, Six Months Ended June 30, 2022 2021 2022 2021 (unaudited) (unaudited) Operating lease expense $ 261 $ 261 $ 521 $ 521 Variable lease expense 64 128 196 256 Total lease expense, net $ 325 $ 389 $ 717 $ 777 Variable lease costs are primarily related to payments made to lessors for common area maintenance, property taxes, insurance, and other operating expenses. The Company did not have any short-term leases or finance leases for the three and six months ended June 30, 2022 and 2021, respectively. The weighted average remaining lease term and weighted average discount rate for operating leases were as follows: As of June 30, 2022 2021 (unaudited) Weighted average remaining lease term (in years) 3.0 4.0 Weighted average discount rate percentage 3.50 % 3.50 % Supplemental cash flow information related to leases under which the Company is the lessee was as follows (amounts in thousands): Three Months Ended June 30, Six Months Ended June 30, 2022 2021 2022 2021 (unaudited) (unaudited) Cash paid for amounts included in the measurement of operating leases $ 377 $ 316 $ 754 $ 632 As of June 30, 2022, future minimum payments under the Company's non-cancelable operating lease under ASC 842 were as follows (in thousands): Operating Six months ending December 31, 2022 $ 801 2023 1,636 2024 1,685 2025 845 Thereafter — Total future lease payments 4,967 Less: imputed interest ( 261 ) Total operating lease liabilities $ 4,706 |
Commitments and Contingencies
Commitments and Contingencies | 6 Months Ended |
Jun. 30, 2022 | |
Commitments and Contingencies Disclosure [Abstract] | |
Commitments and Contingencies | 6. Commitments and Contingencies From time to time, the Company may be subject to various claims and suits arising in the ordinary course of business. The Company is not currently a party to any legal proceedings the outcome of which the Company believes, if determined adversely to the Company, would individually or in the aggregate have a material adverse effect on the Company’s business, operating results or financial condition. |
Stockholders' Equity
Stockholders' Equity | 6 Months Ended |
Jun. 30, 2022 | |
Equity [Abstract] | |
Stockholders' Equity | 7. Stockholders’ Equity 2020 Equity Incentive Plan The Company may grant awards of common stock under the 2020 Equity Incentive Plan (the "2020 Plan") to the Company’s employees, consultants and non-employee directors pursuant to option awards, stock appreciation rights awards, restricted stock awards, restricted stock unit awards, performance stock awards, performance stock unit awards and other stock-based awards. As of June 30, 2022 and December 31, 2021 , the total number of common shares authorized for issuance under the 2020 Plan was 7,658,509 and 6,226,540 , respective ly. On January 1st of each year, commencing with the first January 1st following the effective date of the 2020 Plan, the shares authorized for issuance under the 2020 Plan shall be increased by a number of shares equal to the lesser of 4% of the total number of shares outstanding on the immediately preceding December 31st and such lesser number of shares determined by the Company’s board of directors. The maximum term of the options granted under the 2020 Plan is no more than ten years. Awards under the 2020 Plan generally vest at 25 % one year from the vesting commencement date and ratably each month thereafter for a period of 36 months , subject to continuous service. Stock-based compensation expense for the three and six months ended June 30, 2022 and 2021 has been reported in the condensed consolidated statements of operations and comprehensive loss as follows (in thousands): Three Months Ended Six Months Ended 2022 2021 2022 2021 Research and development $ 1,398 $ 1,154 $ 2,698 $ 2,109 General and administrative 2,444 11,144 4,776 14,832 Total $ 3,842 $ 12,298 $ 7,474 $ 16,941 Restricted Stock Units The following table summarizes RSU activity under the 2020 Plan for the six months ended June 30, 2022: Number of Weighted - Average Outstanding at December 31, 2021 975,046 $ 18.00 Granted — $ — Vested ( 224,353 ) $ 18.00 Forfeited ( 10,734 ) $ 18.00 Outstanding at June 30, 2022 739,959 $ 18.00 As of June 30, 2022, total unrecognized stock-based compensation expense for RSUs was $ 13.3 million, which is expected to be recognized over a remaining weighted-average period of approximately 1.8 years . During the six months ended June 30, 2021, the Company modified 138,461 RSU's under the Transition Agreement (See Note 9). Stock Options The following table summarizes stock option activity under the 2020 Plan for the six months ended June 30, 2022: Number of Weighted - Average Weighted -Average Aggregate Balance at December 31, 2021 1,086,902 $ 26.76 9.22 $ 991,495 Granted 1,645,200 $ 6.40 Exercised — $ — Forfeited ( 4,766 ) $ 11.63 Balance at June 30, 2022 2,727,336 $ 14.50 9.25 $ 62,168 Vested and expected to vest at June 30, 2022 2,727,336 $ 15.49 9.40 $ 62,168 Exercisable at June 30, 2022 343,103 8.28 $ — As of June 30, 2022 , total unrecognized stock-based compensation cost for unvested common stock options was $ 18.1 million, which is expected to be recognized over a remaining weighted-average period of approximately 3.3 years. The weighted- average grant date fair value of stock options granted during the six months ended June 30, 2022 was $ 4.07 per share . The total fair value of options vested during the six months ended June 30, 2022 was $ 3.8 million. During the six months ended June 30, 2021 the Company modified 7,747 stock options under the Transition Agreement (See Note 9). The assumptions used in the Black-Scholes option pricing model to determine the fair value of stock option grants were as follows: Six Months Ended 2022 2021 Expected volatility 74.8 % 74.8 % Risk-free interest rate 2.05 % 0.98 % Expected dividend yield 0.0 % 0.0 % Expected term 6.04 years 5.94 years Expected volatility. As the Company’s common stock does not have a significant trading history, the expected volatility assumption is based on volatilities of a peer group of similar companies whose share prices are publicly available. The peer group was developed based on companies in the biotechnology industry. Risk-free interest rate. The Company bases the risk-free interest rate assumption on the U.S. Treasury’s rates for U.S. Treasury zero-coupon bonds with maturities similar to those of the expected term of the award being valued. Expected dividend yield. The Company bases the expected dividend yield assumption on the fact that it has never paid cash dividends and has no present plans to pay cash dividends. Expected term. For employees, the expected term represents the period of time that options are expected to be outstanding. Because the Company has minimal historical exercise behavior, it determines the expected life assumption using the simplified method, which is an average of the contractual term of the option and its vesting period. For nonemployees, the expected term is generally the contractual term of the option. Employee Stock Purchase Plan The BioAtla, Inc. Employee Stock Purchase Plan (the “ESPP”) permits participants to purchase common stock through payroll deductions of up to 15 % of their eligible compensation. As of June 30, 2022 and December 31, 2021, a total of 1,229,148 shares and 833,993 shares, respectively, of common stock were authorized for issuance under the ESPP. The number of shares of common stock authorized for issuance will automatically increase on January 1 of each calendar year, from January 1, 2021 through January 1, 2030 by the least of (i) 1.0 % of the total number of common shares of our common stock outstanding on December 31 of the preceding calendar year (calculated on a fully diluted basis), (ii) 929,658 common shares or (iii) a number determined by the Company’s board of directors that is less than (i) and (ii). In February 2021, employees began to enroll in the ESPP and the Company’s first offering period commenced. The Company issued 9,482 common shares under the ESPP during the six months ended June 30, 2022 . Comparatively, the Company issued 5,280 common shares under the ESPP during the six months ended June 30, 2021. As of June 30, 2022 , 1,208,484 shares of common stock remained available for issuance under the ESPP. Stock-based compensation expense related to the ESPP for the three and six months ended June 30, 2022 and 2021 was immaterial. Common Stock Warrants The Company issued warrants in 2016 in connection with certain advisory services. The warrants became exercisable upon our IPO for a period of 365 and 450 days. Upon adoption of ASU No. 2018-07 on October 1, 2020, the measurement date of the warrants became fixed in accordance with the guidance, and such fair value was nominal since the warrants were deeply out-of-the-money. In December 2021, a total of 566,586 warrants with an exercise period of 365 days after our IPO expired unexercised. The remaining 151,088 warrants with an exercise period of 450 days after the Company's IPO expired unexercised in March 2022. Accordingly, there are no remaining common stock warrants outstanding and exercisable as of June 30, 2022. Common Stock Reserved for Future Issuance Common stock reserved for future issuance are as follows in common equivalent shares: June 30, December 31, Warrants for the purchase of common stock — 151,088 Common stock options and restricted stock units issued and outstanding 3,467,295 2,061,948 Awards available for future issuance under the 2020 Plan 3,014,123 3,211,854 Awards available for future issuance under the ESPP 1,208,484 822,811 Total common stock reserved for future issuance 7,689,902 6,247,701 |
Collaboration, License and Opti
Collaboration, License and Option Agreements | 6 Months Ended |
Jun. 30, 2022 | |
Collaboration License And Option Agreements [Abstract] | |
Collaboration, License and Option Agreements | 8. Collaboration, License and Option Agreements BeiGene In April 2019, the Company entered into a Global Co-Development and Collaboration agreement (the “BeiGene Collaboration”) with BeiGene, Ltd. and BeiGene Switzerland GmbH (collectively “BeiGene”), a commercial-stage biopharmaceutical company, for the development, manufacturing and commercialization of the Company’s investigational CAB CTLA-4 antibody (BA3071). The Company and BeiGene amended the Global Co-Development and Collaboration agreement in December 2019 and in October 2020 (the “Amended BeiGene Collaboration”). In 2019, BeiGene paid the Company an upfront non-refundable payment of $ 20.0 million and $ 5.0 million for reimbursement of manufacturing costs. Under the terms of the Amended BeiGene Collaboration, BeiGene was generally responsible for developing BA3071 and for global regulatory filings and commercialization. Subject to the terms of the Amended BeiGene Collaboration, BeiGene held an exclusive license with the Company to develop and manufacture the BA3071 candidate globally, and BeiGene was responsible for all costs of development, manufacturing and commercialization globally. The Amended BeiGene Collaboration provided that the Company was eligible to receive tiered royalties on sales worldwide, subsequent development and regulatory milestone payments globally and commercial milestones in the BeiGene territory. On November 18, 2021, the Company entered into Amendment No. 3 to the Amended BeiGene Collaboration (“Amendment No.3”). Under Amendment No. 3, the Amended BeiGene Collaboration was terminated, subject to survival of certain provisions, and the Company regained the rights to know-how and materials under the Amended BeiGene Collaboration and assumed responsibility for the global development and commercialization of BA3071. As consideration for Amendment No.3, the Company agreed to pay BeiGene mid-single digit royalties on sales worldwide and on a limited basis will share in any upfront and milestone payments received through a sublicense of BA3071. As part of Amendment No.3, the Company reclassified its remaining $ 19.8 million of deferred revenue as a long-term liability which is expected to settle as licensing payments are made to BeiGene in accordance with the resulting amendment. In the event the license is terminated, the liability will be extinguished with no further payment to BeiGene. For the three and six months ended June 30, 2022 and 2021 , the Company did no t recognize any revenue related to the collaboration agreement with BeiGene. As of June 30, 2022 and December 31, 2021 , the Company had a $ 19.8 million Liability to Licensor, and $ 19.8 million of deferred revenue which was classified as current, respectively. Service Contracts Prior to developing its own programs, the Company entered into various fixed price research services contracts. In connection with those service contracts, the Company may receive future milestone payments if certain clinical, regulatory and commercialization milestones are achieved. The Company is also eligible to receive royalties based on certain product sales. The Company recognized revenue of $ 0.3 million, included in “Collaboration and Other Revenue”, for the three and six months ended June 30, 2021 related to the achievement of a clinical milestone on a fixed price service contract. The Company did no t recognize any revenue related to its legacy service contracts during the three or six months ended June 30, 2022. BMS Collaboration In January 2022, the Company entered into a Master Clinical Trial Collaboration Agreement (the “BMS Collaboration”) with Bristol-Myers Squibb Company (“BMS”) pursuant to which the Company and BMS will investigate the Company’s CAB-ADC candidates, mecbotamab vedotin (BA3011) and ozuriftamab vedotin (BA3021), each in combination with Opdivo (the “BMS Compound”) in clinical trials (each a “Combined Therapy Study”). Opdivo has received approval for several anti-cancer indications. Under the BMS Collaboration, the Company will serve as the study sponsor for each Combined Therapy Study and will be responsible for the costs associated with trial execution. BMS will supply the Company with clinical drug supply of the BMS Compound at no cost to the Company for each study as well as provide input on certain clinical and regulatory aspects of each Combined Therapy Study in exchange for jointly owning clinical data. The BMS collaboration may be early terminated if a party is in material breach, if either party files for bankruptcy, or due to the existence of a material safety issue. Subject to earlier termination, the BMS Collaboration shall remain in effect until completion and delivery of final study documents for each of the Combined Therapy Study to both parties. Himalaya Therapeutics Exclusive Rights Agreement On January 1, 2020, the Company entered into an Amended and Restated Exclusive Rights Agreement (the “Amended Rights Agreement”) with Himalaya Therapeutics SEZC. Under the terms of the Amended Rights Agreement, Himalaya Therapeutics SEZC acquired the rights to 10 CAB-antibodies for the territory of China, Macao, Hong Kong and Taiwan with future rights to 2 or more CAB-antibodies, global rights to a CAB-HER2-bispecific-antibody and global co-development rights with us to an IL-22 non-CAB-antibody. Payments to the Company may include upfront payments, milestone payments and double-digit royalties, which represent a variable interest held by the Company, but no payments have been made to the Company to date. Himalaya Therapeutics SEZC is a related party. |
Related Party Transactions
Related Party Transactions | 6 Months Ended |
Jun. 30, 2022 | |
Related Party Transactions [Abstract] | |
Related party transactions | 9. Related Party Transactions Carolyn Anderson Short Transition Agreement On March 23, 2021, the Company entered into a transition agreement with Ms. Anderson Short, our Co-founder and Executive Vice President and Chief of Intellectual Property and Strategy. Pursuant to this transition agreement, Ms. Anderson Short continued in her role with the same base salary and employee benefits until her employment with the Company was terminated on May 31, 2021. Upon her separation from the Company and subject to her execution of a release of claims, Ms. Anderson Short received the following severance benefits as set forth in the transition agreement, which satisfied existing severance obligations owing to her under a legacy pre-IPO severance agreement she had entered into with the Company on July 1, 2018: (i) a lump sum payment equal to 18 months of Ms. Anderson Short’s then-current base salary, (ii) a payment at her targeted bonus rate for 2021, pro-rated to the date of her termination of employment, and (iii) full accelerated vesting of her equity awards including 7,747 stock options and 138,461 restricted stock units. The modification of these equity awards resulted in an incremental fair value of $ 7.0 million which was recognized on a straight-line basis over the transition service period which ended on the separation date. For the three and six months ended June 30, 2021 , the Company recognized $ 0.8 million and $ 1.0 million, respectively, related to the lump sum salary payment and target bonus. The Company also recognized non-cash stock-based compensation charges of $ 8.4 million and $ 9.4 million related to the modified equity awards for the three and six months ended June 30, 2021, respectively. No unrecognized stock-based compensation remained as of June 30, 2021. Himalaya Therapeutics Clinical Trial Agreement In April 2022, the Company entered into a Clinical Trial Agreement with Himalaya Therapeutics SEZC. Under the agreement, Himalaya Therapeutics SEZC agreed to provide services related to the initiation of clinical trials for BA3021 in the People’s Republic of China. For the first year following effectiveness of the agreement, the Company has agreed to pay Himalaya Therapeutics SEZC for the full-time use of two of its personnel. Payments are due and payable by BioAtla to Himalaya Therapeutics SEZC on a quarterly calendar basis and are non-refundable. For the three and six months ended June 30, 2022, the Company recognized $ 0.1 million in research and development expense related to the Clinical Trial Agreement. The Company did not have any amounts due from or due to Himalaya Therapeutics SEZC as of June 30, 2022. |
401(k) Plan
401(k) Plan | 6 Months Ended |
Jun. 30, 2022 | |
Retirement Benefits [Abstract] | |
401(k) Plan | 10. 401(k) Plan The Company maintains a defined contribution 401(k) plan available to eligible employees. Employee contributions are voluntary and are determined on an individual basis, limited to the maximum amount allowable under federal tax regulations. The Company, at its discretion, may make certain matching contributions to the 401(k) plan. As of June 30, 2022 and December 31, 2021 , the Company had no t made any matching contributions. |
Organization and Summary of S_2
Organization and Summary of Significant Accounting Policies (Policies) | 6 Months Ended |
Jun. 30, 2022 | |
Accounting Policies [Abstract] | |
Organization | Organization BioAtla, LLC was formed in Delaware in March 2007 and, after undergoing two separate reorganizations in 2019 and in 2020, was converted to a Delaware corporation in July 2020 and was renamed BioAtla, Inc. (the “Company”). The Company has a proprietary platform for creating biologics, including its conditionally active biologics (“CAB” or “CABs”). CABs have been designed to be active only under certain conditions found in diseased tissue, while remaining inactive in normal tissue. The Company is currently in clinical development of its two lead CAB antibody drug conjugates (“CAB ADC”) targeting AXL and ROR2 receptors, and its CAB immune-oncology antibody targeting CTLA-4. |
Basis of Presentation and Principles of Consolidation | Basis of Presentation and Principles of Consolidation Prior to the reorganization in July 2020 (or "Corporate Reorganization"), the consolidated financial statements included the accounts of BioAtla, LLC and those of its majority owned subsidiary Himalaya Therapeutics SEZC that had no material operations. Himalaya Therapeutics SEZC also had a wholly owned subsidiary, Himalaya Therapeutics HK Limited that had no material operations. All intercompany balances were eliminated in consolidation. In connection with the Corporate Reorganization, Himalaya Therapeutics SEZC and Himalaya Therapeutics HK Limited were deconsolidated without material impact to the consolidated financial statements. Subsequent to the Corporate Reorganization, BioAtla, Inc. became a single legal entity with no consolidated variable interest entities ("VIEs") or subsidiaries. The unaudited condensed consolidated financial statements as of June 30, 2022, and for the three and six months ended June 30, 2022 and 2021, have been prepared in accordance with the rules and regulations of the Securities and Exchange Commission (“SEC”), and with accounting principles generally accepted in the United States (“GAAP”) applicable to interim financial statements. These unaudited condensed consolidated financial statements have been prepared on the same basis as the audited financial statements and include all adjustments, consisting of only normal recurring accruals, which in the opinion of management are necessary to present fairly the Company’s financial position as of the interim date and results of operations for the interim periods presented. Interim results are not necessarily indicative of results for a full year or future periods. These unaudited condensed consolidated financial statements should be read in conjunction with the Company’s audited financial statements for the year ended December 31, 2021 , included in its Annual Report on Form 10-K filed with the SEC on February 28, 2022. |
Liquidity and Going Concern | Liquidity and Going Concern The Company has incurred cumulative operating losses and negative cash flows from operations since its inception and expects to continue to incur significant expenses and operating losses for the foreseeable future as it continues the development of its product candidates. As of June 30, 2022, the Company had an accumulated deficit of $ 239.5 million . The Company plans to continue to fund its losses from operations and capital funding needs through public or private equity or debt financings or other sources. If the Company is not able to secure adequate additional funding, the Company may be forced to make reductions in spending, extend payment terms with suppliers, liquidate assets where possible, or suspend or curtail planned programs. Any of these actions could materially harm the Company’s business, results of operations and future prospects. Management is required to perform a two-step analysis of the Company’s ability to continue as a going concern. Management must first evaluate whether there are conditions and events that raise substantial doubt about the Company’s ability to continue as a going concern (Step 1). If management concludes that substantial doubt is raised, management is also required to consider whether its plans alleviate that doubt (Step 2). Management’s assessment included the preparation of cash flow forecasts resulting in management’s conclusion that there is not substantial doubt about the Company’s ability to continue as a going concern as its current cash and cash equivalents will be sufficient to fund the Company’s operations for a period of at least one year from the issuance date of these unaudited condensed consolidated financial statements. |
Use of Estimates | Use of Estimates The preparation of the Company’s condensed consolidated financial statements requires it to make estimates and assumptions that impact the reported amounts of assets, liabilities, revenues and expenses and the disclosure of contingent assets and liabilities in the Company’s condensed consolidated financial statements and accompanying notes. The most significant estimates in the Company’s condensed consolidated financial statements relate to revenue recognition, accruals for research and development costs, and equity-based compensation. These estimates and assumptions are based on current facts, historical experience and various other factors believed to be reasonable under the circumstances, the results of which form the basis for making judgments about the carrying values of assets and liabilities and the recording of revenue and expenses that are not readily apparent from other sources. Actual results may differ materially and adversely from these estimates. To the extent there are material differences between the estimates and actual results, the Company’s future results of operations will be affected. |
Concentrations of Risk | Concentrations of Risk Financial instruments that potentially subject the Company to a significant concentration of credit risk consist primarily of cash and cash equivalents. The Company maintains deposits in federally insured financial institutions in excess of federally insured limits. The Company has not experienced any losses in such accounts and management believes that the Company is not exposed to significant credit risk due to the financial position of the depository institutions in which those deposits are held. |
Stock-Based Compensation | Stock-Based Compensation Stock-based compensation expense represents the grant date fair value of equity awards, consisting of stock options, restricted stock units (“RSUs”) and employee stock purchase plan rights, over the requisite service period of the awards (usually the vesting period) on a straight-line basis. The Company estimates the fair value of stock option grants and employee stock purchase plan rights using the Black-Scholes option pricing model. Prior to the Company’s IPO, the fair value of RSUs was based on the estimated fair value of the underlying common stock on the date of grant and, subsequent to the Company’s IPO, the fair value is based on the closing sales price of the Company’s common stock on the date of grant. Equity award forfeitures are recognized as they occur. |
Leases | Leases The Company determines if an arrangement is a lease at inception. An arrangement is or contains a lease if it conveys the right to control the use of an identified asset for a period of time in exchange for consideration. If a lease is identified, classification is determined at lease commencement. Operating lease liabilities are recognized at the present value of the future lease payments at the lease commencement date. The Company’s leases do not provide an implicit interest rate and therefore the Company estimates its incremental borrowing rate to discount lease payments. The incremental borrowing rate reflects the interest rate that the Company would have to pay to borrow on a collateralized basis an amount equal to the lease payments in a similar economic environment over a similar term. Operating lease right-of-use (“ROU”) assets are based on the corresponding lease liability adjusted for any lease payments made at or before commencement, initial direct costs, and lease incentives. Renewals or early terminations are not accounted for unless the Company is reasonably certain to exercise these options. Operating lease expense is recognized and the ROU asset is amortized on a straight-line basis over the lease term. Variable lease costs are not included in the calculation of the ROU asset and the related lease liability and are recognized as incurred. The Company has a single lease agreement with lease and non-lease components, which are accounted for as a single lease component. Payments for short-term leases, defined as leases with a term of twelve months or less, are expensed on a straight-line basis over the lease term. The Company does not currently have any short-term leases. Operating leases are included in operating lease right-of-use assets, operating lease liabilities, and operating lease liabilities, non-current on the Company’s consolidated balance sheets. The Company does not have any finance leases. |
Comprehensive Loss | Comprehensive Loss Comprehensive loss is defined as a change in equity during a period from transactions and other events and circumstances from non-owner sources. There have been no items qualifying as other comprehensive loss and, therefore, for all periods presented, the Company’s comprehensive loss was the same as its reported net loss. |
Net Loss Per Share | Net Loss Per Share Basic net loss per common share is computed by dividing the net loss by the weighted-average number of common shares outstanding for the period, without consideration for potentially dilutive securities. Diluted net loss per share is computed by dividing the net loss by the weighted-average number of common shares and dilutive common stock equivalents outstanding for the period determined using the treasury-stock method. Dilutive common stock equivalents are comprised of RSUs, common stock options outstanding under the Company’s stock option plan, and contingently issuable shares under the Company's ESPP plan. Potentially dilutive securities not included in the calculation of diluted net loss per share because to do so would be anti-dilutive are as follows (in common stock equivalents): Six Months Ended 2022 2021 Common stock warrants — 717,674 Common stock options 2,727,336 850,149 Restricted stock units 739,959 1,781,576 ESPP shares 41,292 — Total 3,508,587 3,349,399 |
Recent Accounting Pronouncements | Recent Accounting Pronouncements There were no new accounting standards that had a material impact on the Company’s consolidated financial statements during the three or six months ended June 30, 2022, and there were no other new accounting standards or pronouncements that were issued but not yet effective as of June 30, 2022 that the Company expects to have a material impact on its consolidated financial statements. |
Organization and Summary of S_3
Organization and Summary of Significant Accounting Policies (Tables) | 6 Months Ended |
Jun. 30, 2022 | |
Accounting Policies [Abstract] | |
Schedule of Anti-dilutive Securities Excluded from Calculation of Diluted Net Loss Per Share | Potentially dilutive securities not included in the calculation of diluted net loss per share because to do so would be anti-dilutive are as follows (in common stock equivalents): Six Months Ended 2022 2021 Common stock warrants — 717,674 Common stock options 2,727,336 850,149 Restricted stock units 739,959 1,781,576 ESPP shares 41,292 — Total 3,508,587 3,349,399 |
Balance Sheet Details (Tables)
Balance Sheet Details (Tables) | 6 Months Ended |
Jun. 30, 2022 | |
Balance Sheet Related Disclosures [Abstract] | |
Schedule Of Prepaid Expenses Other Current Assets | Prepaid expenses and other current assets consist of the following (in thousands): June 30, December 31, Prepaid research and development $ 2,739 $ 1,811 Prepaid insurance 1,471 — Other prepaid expenses and current assets 697 502 Total $ 4,907 $ 2,313 |
Schedule of Property and Equipment | Property and equipment consist of the following (in thousands): Useful life June 30, December 31, Furniture, fixtures and office equipment 3 - 7 $ 2,172 $ 2,123 Laboratory equipment 5 2,265 2,123 Leasehold improvements 2 - 3 3,687 3,687 8,124 7,933 Less accumulated depreciation and amortization ( 4,847 ) ( 4,257 ) Total $ 3,277 $ 3,676 |
Schedule of Accounts Payable and Accrued Expenses | Accounts payable and accrued expenses consist of the following (in thousands): June 30, December 31, Accounts payable $ 4,822 $ 1,179 Accrued compensation 1,833 2,671 Accrued research and development 15,598 13,501 Other accrued expenses 1,779 1,073 Total $ 24,032 $ 18,424 |
Leases (Tables)
Leases (Tables) | 6 Months Ended |
Jun. 30, 2022 | |
Lessee Disclosure [Abstract] | |
Components of Lease Expense | The components of lease expense included in the Company’s condensed consolidated statements of operations include (in thousands): Three Months Ended June 30, Six Months Ended June 30, 2022 2021 2022 2021 (unaudited) (unaudited) Operating lease expense $ 261 $ 261 $ 521 $ 521 Variable lease expense 64 128 196 256 Total lease expense, net $ 325 $ 389 $ 717 $ 777 |
Summary of Weighted Average Remaining Lease Term and Weighted Average Discount Rate | The weighted average remaining lease term and weighted average discount rate for operating leases were as follows: As of June 30, 2022 2021 (unaudited) Weighted average remaining lease term (in years) 3.0 4.0 Weighted average discount rate percentage 3.50 % 3.50 % |
Supplemental Cash Flow Information Related to Leases | Supplemental cash flow information related to leases under which the Company is the lessee was as follows (amounts in thousands): Three Months Ended June 30, Six Months Ended June 30, 2022 2021 2022 2021 (unaudited) (unaudited) Cash paid for amounts included in the measurement of operating leases $ 377 $ 316 $ 754 $ 632 |
Maturities of Operating Lease Liabilities | As of June 30, 2022, future minimum payments under the Company's non-cancelable operating lease under ASC 842 were as follows (in thousands): Operating Six months ending December 31, 2022 $ 801 2023 1,636 2024 1,685 2025 845 Thereafter — Total future lease payments 4,967 Less: imputed interest ( 261 ) Total operating lease liabilities $ 4,706 |
Stockholders' Equity (Tables)
Stockholders' Equity (Tables) | 6 Months Ended |
Jun. 30, 2022 | |
Equity [Abstract] | |
Schedule of Stock-Based Compensation Expense | Stock-based compensation expense for the three and six months ended June 30, 2022 and 2021 has been reported in the condensed consolidated statements of operations and comprehensive loss as follows (in thousands): Three Months Ended Six Months Ended 2022 2021 2022 2021 Research and development $ 1,398 $ 1,154 $ 2,698 $ 2,109 General and administrative 2,444 11,144 4,776 14,832 Total $ 3,842 $ 12,298 $ 7,474 $ 16,941 |
Summary of Restricted Stock Units | The following table summarizes RSU activity under the 2020 Plan for the six months ended June 30, 2022: Number of Weighted - Average Outstanding at December 31, 2021 975,046 $ 18.00 Granted — $ — Vested ( 224,353 ) $ 18.00 Forfeited ( 10,734 ) $ 18.00 Outstanding at June 30, 2022 739,959 $ 18.00 |
Summary of Stock Option Activity | The following table summarizes stock option activity under the 2020 Plan for the six months ended June 30, 2022: Number of Weighted - Average Weighted -Average Aggregate Balance at December 31, 2021 1,086,902 $ 26.76 9.22 $ 991,495 Granted 1,645,200 $ 6.40 Exercised — $ — Forfeited ( 4,766 ) $ 11.63 Balance at June 30, 2022 2,727,336 $ 14.50 9.25 $ 62,168 Vested and expected to vest at June 30, 2022 2,727,336 $ 15.49 9.40 $ 62,168 Exercisable at June 30, 2022 343,103 8.28 $ — |
Summary of Assumptions Used in Black-Scholes Model | The assumptions used in the Black-Scholes option pricing model to determine the fair value of stock option grants were as follows: Six Months Ended 2022 2021 Expected volatility 74.8 % 74.8 % Risk-free interest rate 2.05 % 0.98 % Expected dividend yield 0.0 % 0.0 % Expected term 6.04 years 5.94 years |
Schedule of Common Stock Reserved for Future Issuance | Common stock reserved for future issuance are as follows in common equivalent shares: June 30, December 31, Warrants for the purchase of common stock — 151,088 Common stock options and restricted stock units issued and outstanding 3,467,295 2,061,948 Awards available for future issuance under the 2020 Plan 3,014,123 3,211,854 Awards available for future issuance under the ESPP 1,208,484 822,811 Total common stock reserved for future issuance 7,689,902 6,247,701 |
Organization and Summary of S_4
Organization and Summary of Significant Accounting Policies - Additional Information (Details) - USD ($) $ in Thousands | 6 Months Ended | |
Jun. 30, 2022 | Dec. 31, 2021 | |
Accounting Policies [Abstract] | ||
Entity incorporation state country code | DE | |
Company formation date | 2007-03 | |
Accumulated deficit | $ 239,479 | $ 186,319 |
Organization and Summary of S_5
Organization and Summary of Significant Accounting Policies - Schedule of Anti-dilutive Securities Excluded from Calculation of Diluted Net Loss Per Share (Details) - shares | 6 Months Ended | |
Jun. 30, 2022 | Jun. 30, 2021 | |
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] | ||
Anti-dilutive securities excluded from calculation of diluted net loss per share | 3,508,587 | 3,349,399 |
Common Stock Warrants | ||
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] | ||
Anti-dilutive securities excluded from calculation of diluted net loss per share | 0 | 717,674 |
Common Stock Options | ||
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] | ||
Anti-dilutive securities excluded from calculation of diluted net loss per share | 2,727,336 | 850,149 |
Restricted Stock Units (RSUs) | ||
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] | ||
Anti-dilutive securities excluded from calculation of diluted net loss per share | 739,959 | 1,781,576 |
ESPP Shares | ||
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] | ||
Anti-dilutive securities excluded from calculation of diluted net loss per share | 41,292 | 0 |
Balance Sheet Details - Schedul
Balance Sheet Details - Schedule Of Prepaid Expenses Other Current Assets (Details) - USD ($) $ in Thousands | Jun. 30, 2022 | Dec. 31, 2021 |
Balance Sheet Related Disclosures [Abstract] | ||
Prepaid research and development | $ 2,739 | $ 1,811 |
Prepaid insurance | 1,471 | 0 |
Other prepaid expenses and current assets | 697 | 502 |
Total | $ 4,907 | $ 2,313 |
Balance Sheet Details - Sched_2
Balance Sheet Details - Schedule of Property and Equipment (Details) - USD ($) $ in Thousands | 6 Months Ended | |
Jun. 30, 2022 | Dec. 31, 2021 | |
Property Plant And Equipment [Line Items] | ||
Property, plant and equipment, gross | $ 8,124 | $ 7,933 |
Less accumulated depreciation and amortization | (4,847) | (4,257) |
Total | 3,277 | 3,676 |
Furniture Fixtures And Office Equipment | ||
Property Plant And Equipment [Line Items] | ||
Property, plant and equipment, gross | $ 2,172 | 2,123 |
Furniture Fixtures And Office Equipment | Minimum | ||
Property Plant And Equipment [Line Items] | ||
Property plant and equipment useful life | 3 years | |
Furniture Fixtures And Office Equipment | Maximum | ||
Property Plant And Equipment [Line Items] | ||
Property plant and equipment useful life | 7 years | |
Laboratory Equipment | ||
Property Plant And Equipment [Line Items] | ||
Property plant and equipment useful life | 5 years | |
Property, plant and equipment, gross | $ 2,265 | 2,123 |
Leasehold Improvements | ||
Property Plant And Equipment [Line Items] | ||
Property, plant and equipment, gross | $ 3,687 | $ 3,687 |
Leasehold Improvements | Minimum | ||
Property Plant And Equipment [Line Items] | ||
Property plant and equipment useful life | 2 years | |
Leasehold Improvements | Maximum | ||
Property Plant And Equipment [Line Items] | ||
Property plant and equipment useful life | 3 years |
Balance Sheet Details - Sched_3
Balance Sheet Details - Schedule of Accounts Payable and Accrued Expenses (Details) - USD ($) $ in Thousands | Jun. 30, 2022 | Dec. 31, 2021 |
Balance Sheet Related Disclosures [Abstract] | ||
Accounts payable | $ 4,822 | $ 1,179 |
Accrued compensation | 1,833 | 2,671 |
Accrued research and development | 15,598 | 13,501 |
Other accrued expenses | 1,779 | 1,073 |
Total | $ 24,032 | $ 18,424 |
Fair Value Measurements - Addit
Fair Value Measurements - Additional Information (Details) - USD ($) | Jun. 30, 2022 | Dec. 31, 2021 |
Fair Value Disclosures [Abstract] | ||
Assets measured at fair value | $ 0 | $ 0 |
Liability measured at fair value | $ 0 | $ 0 |
Debt - Additional Information (
Debt - Additional Information (Details) - USD ($) | 3 Months Ended | 6 Months Ended | |||
Jun. 30, 2022 | Jun. 30, 2021 | Jun. 30, 2022 | Jun. 30, 2021 | Dec. 31, 2021 | |
Debt Instrument [Line Items] | |||||
Debt description | The Company did not have any outstanding debt as of June 30, 2022 or December 31, 2021. As of June 30, 2021, the Company had $0.7 million outstanding under a promissory note issued pursuant to the Paycheck Protection Program (“PPP”) of the CARES Act. | ||||
Interest Expense | $ 1,000 | $ 3,000 | |||
Outstanding Debt [Member] | |||||
Debt Instrument [Line Items] | |||||
Interest Expense | 1,000 | 3,000 | |||
Debt Instrument Outstanding Principal Amount | $ 0 | $ 0 | $ 0 | ||
Other Debt Obligations [Member] | |||||
Debt Instrument [Line Items] | |||||
Debt Instrument Outstanding Principal Amount | $ 700,000 | $ 700,000 |
Leases (Additional Information)
Leases (Additional Information) (Details) | 6 Months Ended |
Jun. 30, 2022 | |
Leases [Abstract] | |
Lessor Operating Leases Option To Extend | 5 years |
Lessor, Operating Lease, Option to Extend | The lease expires in July 2025 and the Company has an option to extend the term of the lease for an additional five years. Additionally, the lease includes certain rent abatement, rent escalations, tenant improvement allowances and additional charges for common area maintenance and other costs. |
Leases - Components of Lease Ex
Leases - Components of Lease Expense (Details) - USD ($) $ in Thousands | 3 Months Ended | 6 Months Ended | ||
Jun. 30, 2022 | Jun. 30, 2021 | Jun. 30, 2022 | Jun. 30, 2021 | |
Leases [Abstract] | ||||
Operating lease expense | $ 261 | $ 261 | $ 521 | $ 521 |
Variable lease expense | 64 | 128 | 196 | 256 |
Lease, Cost, Total | $ 325 | $ 389 | $ 717 | $ 777 |
Leases - Summary of Weighted Av
Leases - Summary of Weighted Average Remaining Lease Term And Weighted Average Discount Rate (Details) | Jun. 30, 2022 | Jun. 30, 2021 |
Leases [Abstract] | ||
Weighted average remaining lease term (in years) | 3 years | 4 years |
Weighted average discount rate percentage | 3.50% | 3.50% |
Leases - Supplemental Cash Flow
Leases - Supplemental Cash Flow Information Related to Leases (Details) - USD ($) $ in Thousands | 3 Months Ended | 6 Months Ended | ||
Jun. 30, 2022 | Jun. 30, 2021 | Jun. 30, 2022 | Jun. 30, 2021 | |
Leases [Abstract] | ||||
Cash paid for amounts included in the measurement of operating leases | $ 377 | $ 316 | $ 754 | $ 632 |
Leases - Maturities of Operatin
Leases - Maturities of Operating Lease Liabilities (Details) $ in Thousands | Jun. 30, 2022 USD ($) |
Leases [Abstract] | |
Six months ending December 31, 2022 | $ 801 |
2023 | 1,636 |
2024 | 1,685 |
2025 | 845 |
Thereafter | 0 |
Total future lease payments | 4,967 |
Less: imputed interest | (261) |
Total operating lease liabilities | $ 4,706 |
Stockholders' Equity - Addition
Stockholders' Equity - Additional Information (Details) - USD ($) $ / shares in Units, $ in Thousands | 3 Months Ended | 6 Months Ended | 12 Months Ended | ||||
Jun. 30, 2022 | Jun. 30, 2021 | Mar. 31, 2021 | Jun. 30, 2022 | Jun. 30, 2021 | Dec. 31, 2021 | Mar. 31, 2022 | |
Class Of Stock [Line Items] | |||||||
Beginning balances | $ 164,952 | $ 164,952 | $ 210,821 | ||||
Common stock, shares issued (in shares) | 35,993,458 | 35,993,458 | 35,799,233 | ||||
Stock-based compensation | $ 3,842 | $ 12,298 | $ 7,474 | $ 16,941 | |||
Total fair value of options vested | $ 3,800 | ||||||
Total number of common shares reserved for issuance | 7,689,902 | 7,689,902 | 6,247,701 | ||||
Common Stock, Shares Authorized | 350,000,000 | 350,000,000 | 350,000,000 | ||||
Share-Based Compensation Arrangement by Share-Based Payment Award, Purchase Price of Common Stock, Percent | 15% | ||||||
Common Stock, Capital Shares Reserved for Future Issuance | 7,689,902 | 7,689,902 | 6,247,701 | ||||
Common stock authorized for issuance under plan | 350,000,000 | 350,000,000 | 350,000,000 | ||||
Warrants Expired And Unexercised | 566,586 | ||||||
Equity Option | |||||||
Class Of Stock [Line Items] | |||||||
Share-based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount | $ 18,100 | $ 18,100 | |||||
Share-based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition | 3 years 3 months 18 days | ||||||
Share-based Payment Arrangement, Plan Modification, Number of Shares | 7,747 | ||||||
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value | $ 4.07 | ||||||
Restricted Stock Units (RSUs) | |||||||
Class Of Stock [Line Items] | |||||||
Share-based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount | $ 13,300 | $ 13,300 | |||||
Share-based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition | 1 year 9 months 18 days | ||||||
Share-based Payment Arrangement, Plan Modification, Number of Shares | 138,461 | ||||||
2020 Equity Incentive Plan [Member] | |||||||
Class Of Stock [Line Items] | |||||||
Common shares authorized for issuance | 7,658,509 | 7,658,509 | 6,226,540 | ||||
Shares available for awards, description | On January 1st of each year, commencing with the first January 1st following the effective date of the 2020 Plan, the shares authorized for issuance under the 2020 Plan shall be increased by a number of shares equal to the lesser of 4% of the total number of shares outstanding on the immediately preceding December 31st and such lesser number of shares determined by the Company’s board of directors. | ||||||
Vesting percentage | 25% | ||||||
Vesting period | 36 months | ||||||
Vesting terms, description | Awards under the 2020 Plan generally vest at 25% one year from the vesting commencement date and ratably each month thereafter for a period of 36 months, subject to continuous service. | ||||||
Employees Stock Purchase Plan [Member] | |||||||
Class Of Stock [Line Items] | |||||||
Total number of common shares reserved for issuance | 1,208,484 | 1,208,484 | |||||
Common Stock, Shares Authorized | 1,229,148 | 1,229,148 | 833,993 | ||||
Common Stock, Capital Shares Reserved for Future Issuance | 1,208,484 | 1,208,484 | |||||
Common stock authorized for issuance under plan | 1,229,148 | 1,229,148 | 833,993 | ||||
Share Based Compensation Arrangement By Share Based Payment Award Percentage Of Outstanding Stock Maximum | 1% | ||||||
Maximum annual increase of shares of common stock authorized for issuance | 929,658 | ||||||
Common Stock | |||||||
Class Of Stock [Line Items] | |||||||
Issuance of common stock for Employee Stock Purchase Plan, shares | 9,482 | 5,280 | 9,482 | 5,280 | |||
Class B Common Stock | |||||||
Class Of Stock [Line Items] | |||||||
Common stock, shares issued (in shares) | 1,492,059 | 1,492,059 | 1,492,059 | ||||
Common Stock, Shares Authorized | 15,368,569 | 15,368,569 | 15,368,569 | ||||
Common stock authorized for issuance under plan | 15,368,569 | 15,368,569 | 15,368,569 | ||||
IPO [Member] | Maximum | |||||||
Class Of Stock [Line Items] | |||||||
Warrants exercise period | 450 days | 450 days | |||||
IPO [Member] | Minimum | |||||||
Class Of Stock [Line Items] | |||||||
Warrants exercise period | 365 days | 365 days | |||||
IPO [Member] | Common stock warrants | |||||||
Class Of Stock [Line Items] | |||||||
Warrants expired (unexercised) | 151,088 | ||||||
Remaining common stock warrants outstanding and exercisable | 0 | ||||||
IPO [Member] | Common stock warrants | Maximum | |||||||
Class Of Stock [Line Items] | |||||||
Warrants exercise period | 450 days | ||||||
IPO [Member] | Common stock warrants | Minimum | |||||||
Class Of Stock [Line Items] | |||||||
Warrants exercise period | 365 days |
Stockholders' Equity - Schedule
Stockholders' Equity - Schedule of Stock-based Compensation Expense (Details) - USD ($) $ in Thousands | 3 Months Ended | 6 Months Ended | ||
Jun. 30, 2022 | Jun. 30, 2021 | Jun. 30, 2022 | Jun. 30, 2021 | |
Class Of Stock [Line Items] | ||||
Stock-based compensation | $ 3,842 | $ 12,298 | $ 7,474 | $ 16,941 |
Research and Development Expense | ||||
Class Of Stock [Line Items] | ||||
Stock-based compensation | 1,398 | 1,154 | 2,698 | 2,109 |
General and Administrative Expense | ||||
Class Of Stock [Line Items] | ||||
Stock-based compensation | $ 2,444 | $ 11,144 | $ 4,776 | $ 14,832 |
Stockholders' Equity - Summary
Stockholders' Equity - Summary of Restricted Stock Units (Details) - Restricted Stock Units (RSUs) | 6 Months Ended |
Jun. 30, 2022 $ / shares shares | |
Class Of Stock [Line Items] | |
Number of Outstanding Shares, Beginning Balance | shares | 975,046 |
Number of Shares, Granted | shares | 0 |
Number of Shares, Vested | shares | (224,353) |
Number of Shares, Forfeited | shares | (10,734) |
Number of Outstanding Shares, Ending Balance | shares | 739,959 |
Weighted Average Grant Date Fair Value, Beginning Balance | $ / shares | $ 18 |
Weighted Average Grant Date Fair Value, Granted | $ / shares | 0 |
Weighted Average Grant Date Fair Value, Vested | $ / shares | 18 |
Weighted Average Grant Date Fair Value, Forfeited | $ / shares | 18 |
Weighted Average Grant Date Fair Value, Ending Balance | $ / shares | $ 18 |
Stockholders' Equity - Summar_2
Stockholders' Equity - Summary of Stock Option Activity (Details) - Equity Option - USD ($) $ / shares in Units, $ in Thousands | 3 Months Ended | 6 Months Ended | 12 Months Ended |
Jun. 30, 2022 | Jun. 30, 2022 | Dec. 31, 2021 | |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] | |||
Number of Shares, Beginning Balance | 1,086,902 | ||
Granted, Number of Shares | 1,645,200 | ||
Forfeited, Number of Shares | (4,766) | ||
Number of Shares, Ending Balance | 2,727,336 | 2,727,336 | 1,086,902 |
Vested and expected to vest, Number of Shares | 2,727,336 | 2,727,336 | |
Exercisable, Number of Shares | 343,103 | 343,103 | |
Outstanding, Beginning Balance, Weighted-Average Exercise Price per Share | $ 26.76 | ||
Granted, Weighted-Average Exercise Price per Share | 6.40 | ||
Forfeited, Weighted-Average Exercise Price per Share | $ 11.63 | ||
Outstanding, Ending Balance, Weighted-Average Exercise Price per Share | $ / shares | 14.50 | 14.50 | $ 26.76 |
Vested and expected to vest, Weighted-Average Exercise Price per Share | $ 15.49 | $ 15.49 | |
Outstanding, Weighted-Average Remaining Contractual Term (years) | 9 years 3 months | 9 years 2 months 19 days | |
Vested and expected to vest, Weighted-Average Remaining Contractual Term (years) | 9 years 4 months 24 days | ||
Exercisable, Weighted-Average Remaining Contractual Term (years) | 8 years 3 months 10 days | ||
Outstanding, Aggregate Intrinsic Value | $ 62,168 | $ 62,168 | $ 991,495 |
Vested and expected to vest, Aggregate Intrinsic Value | $ 62,168 | $ 62,168 |
Stockholders' Equity - Summar_3
Stockholders' Equity - Summary of Assumptions Used in Black-Scholes Model (Details) | 6 Months Ended | |
Jun. 30, 2022 | Jun. 30, 2021 | |
Stockholders' Equity Note [Abstract] | ||
Expected volatility | 74.80% | 74.80% |
Risk-free interest rate | 2.05% | 0.98% |
Expected dividend yield | 0% | 0% |
Expected term | 6 years 14 days | 5 years 11 months 8 days |
Stockholders' Equity - Schedu_2
Stockholders' Equity - Schedule of Common Stock Reserved for Future Issuance (Details) - shares | 6 Months Ended | 12 Months Ended |
Jun. 30, 2022 | Dec. 31, 2021 | |
Class Of Stock [Line Items] | ||
Common Stock, Shares, Issued | 35,993,458 | 35,799,233 |
Common Stock, Shares, Outstanding | 35,993,458 | 35,799,233 |
Total number of common shares reserved for issuance | 7,689,902 | 6,247,701 |
Warrants [Member] | ||
Class Of Stock [Line Items] | ||
Warrants for the purchase of common stock | 0 | 151,088 |
Common Stock Options and Restricted Stock Units [Member] | ||
Class Of Stock [Line Items] | ||
Common Stock, Shares, Issued | 3,467,295 | 2,061,948 |
Common Stock, Shares, Outstanding | 3,467,295 | 2,061,948 |
2020 Plan [Member] | ||
Class Of Stock [Line Items] | ||
Awards available for future issuance | 3,014,123 | 3,211,854 |
Employees Stock Purchase Plan [Member] | ||
Class Of Stock [Line Items] | ||
Awards available for future issuance | 1,208,484 | 822,811 |
Total number of common shares reserved for issuance | 1,208,484 |
Collaboration, License and Op_2
Collaboration, License and Option Agreements - Additional Information (Details) - USD ($) | 3 Months Ended | 6 Months Ended | 12 Months Ended | ||||
Nov. 18, 2021 | Jun. 30, 2022 | Jun. 30, 2021 | Jun. 30, 2022 | Jun. 30, 2021 | Dec. 31, 2019 | Dec. 31, 2021 | |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] | |||||||
Collaboration Amendment Date | 2019-12 | ||||||
Upfront Non-Refundable Payment | $ 20,000,000 | ||||||
Revenues | $ 0 | $ 300,000 | $ 0 | $ 300,000 | |||
Liability to licensor | 19,806,000 | $ 19,806,000 | $ 19,806,000 | ||||
BeiGene | |||||||
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] | |||||||
Collaboration Amendment Date | 2020-10 | ||||||
Reimbursement Of Manufacturing Costs | $ 5,000,000 | ||||||
Revenues | 0 | $ 0 | $ 0 | $ 0 | |||
Current portion of deferred revenue | $ 19,800,000 | 19,800,000 | 19,800,000 | 19,800,000 | |||
License termination information, Description | In the event the license is terminated, the liability will be extinguished with no further payment to BeiGene. | ||||||
Liability to licensor | $ 19,800,000 | $ 19,800,000 | $ 19,800,000 |
Related Party Transactions - Ad
Related Party Transactions - Additional Information (Details) - USD ($) $ in Thousands | 3 Months Ended | 6 Months Ended | |||
Mar. 23, 2021 | Jun. 30, 2022 | Jun. 30, 2021 | Jun. 30, 2022 | Jun. 30, 2021 | |
Related Party Transaction [Line Items] | |||||
Related party transaction, terms and manner of settlement | (i) a lump sum payment equal to 18 months of Ms. Anderson Short’s then-current base salary, (ii) a payment at her targeted bonus rate for 2021, pro-rated to the date of her termination of employment, and (iii) full accelerated vesting of her equity awards including 7,747 stock options and 138,461 restricted stock units. The modification of these equity awards resulted in an incremental fair value of $7.0 million which was recognized on a straight-line basis over the transition service period which ended on the separation date. For the three and six months ended June 30, 2021, the Company recognized $0.8 million and $1.0 million, respectively, related to the lump sum salary payment and target bonus. The Company also recognized non-cash stock-based compensation charges of $8.4 million and $9.4 million related to the modified equity awards for the three and six months ended June 30, 2021, respectively. No unrecognized stock-based compensation remained as of June 30, 2021. | ||||
Non-cash stock-based compensation charges | $ 3,842 | $ 12,298 | $ 7,474 | $ 16,941 | |
Research and development expense | 20,711 | 14,850 | $ 37,634 | 25,273 | |
Himalaya Therapeutics SEZC | |||||
Related Party Transaction [Line Items] | |||||
Description of agreement with related party | In April 2022, the Company entered into a Clinical Trial Agreement with Himalaya Therapeutics SEZC. Under the agreement, Himalaya Therapeutics SEZC agreed to provide services related to the initiation of clinical trials for BA3021 in the People’s Republic of China. For the first year following effectiveness of the agreement, the Company has agreed to pay Himalaya Therapeutics SEZC for the full-time use of two of its personnel. Payments are due and payable by BioAtla to Himalaya Therapeutics SEZC on a quarterly calendar basis and are non-refundable. For the three and six months ended June 30, 2022, the Company recognized $0.1 million in research and development expense related to the Clinical Trial Agreement. The Company did not have any amounts due from or due to Himalaya Therapeutics SEZC as of June 30, 2022. | ||||
Research and development expense | $ 100 | $ 100 | |||
Carolyn Anderson Short | |||||
Related Party Transaction [Line Items] | |||||
Number of accelerated full vesting equity awards including stock options | 7,747 | ||||
Number of accelerated full vesting equity awards including restricted stock units | 138,461 | ||||
Incremental Fair Value | $ 7,000 | ||||
Expense related to Lump Sum Salary Payment and Target Bonus | 800 | 1,000 | |||
Non-cash stock-based compensation charges | 8,400 | 9,400 | |||
Unrecognized stock-based compensation | $ 0 | $ 0 |
401(k) Plan - Additional Inform
401(k) Plan - Additional Information (Details) - USD ($) | 6 Months Ended | 12 Months Ended |
Jun. 30, 2022 | Dec. 31, 2021 | |
Retirement Benefits [Abstract] | ||
Contributions made by Company | $ 0 | $ 0 |