| Document and Entity Information | Oct. 29, 2021 |
| Cover [Abstract] | |
| Amendment Flag | false |
| Entity Central Index Key | 0001827506 |
| Document Type | 8-K |
| Document Period End Date | Oct. 29, 2021 |
| Entity Registrant Name | TALARIS THERAPEUTICS, INC. |
| Entity Incorporation State Country Code | DE |
| Entity File Number | 001-40384 |
| Entity Tax Identification Number | 83-2377352 |
| Entity Address, Address Line One | 570 S. Preston St |
| Entity Address, City or Town | Louisville |
| Entity Address, State or Province | KY |
| Entity Address, Postal Zip Code | 40202 |
| City Area Code | (502) |
| Local Phone Number | 398-9250 |
| Written Communications | false |
| Soliciting Material | false |
| Pre Commencement Tender Offer | false |
| Pre Commencement Issuer Tender Offer | false |
| Security 12b Title | Common Stock, $0.0001 par value per share |
| Trading Symbol | TALS |
| Security Exchange Name | NASDAQ |
| Entity Emerging Growth Company | true |
| Entity Ex Transition Period | false |
