Ginkgo Bioworks (DNA) 10-Q 8 Nov 23 2023 Q3 Quarterly report Financial data

Cover Page

Cover Page - shares	9 Months Ended
	Sep. 30, 2023	Oct. 31, 2023
Document Information [Line Items]
Document Type	10-Q
Document Quarterly Report	true
Document Period End Date	Sep. 30, 2023
Document Transition Report	false
Entity File Number	001-40097
Entity Registrant Name	GINKGO BIOWORKS HOLDINGS, INC.
Entity Incorporation, State or Country Code	DE
Entity Tax Identification Number	87-2652913
Entity Address, Address Line One	27 Drydock Avenue
Entity Address, Address Line One	8th Floor
Entity Address, City or Town	Boston
Entity Address, State or Province	MA
Entity Address, Postal Zip Code	02210
City Area Code	877
Local Phone Number	422-5362
Entity Current Reporting Status	Yes
Entity Interactive Data Current	Yes
Entity Filer Category	Large Accelerated Filer
Entity Small Business	false
Entity Emerging Growth Company	false
Entity Shell Company	false
Entity Central Index Key	0001830214
Current Fiscal Year End Date	--12-31
Amendment Flag	false
Document Fiscal Year Focus	2023
Document Fiscal Period Focus	Q3
Common Class A
Document Information [Line Items]
Title of 12(b) Security	Class A common stock, par value $0.0001 per share
Trading Symbols	DNA
Security Exchange Name	NYSE
Entity Common Stock, Shares Outstanding		1,619,442,071
Warrants to purchase one share of Class A common stock, each at an exercise price of $11.50 per share
Document Information [Line Items]
Title of 12(b) Security	Warrants to purchase one share of Class A common stock, each at an exercise price of $11.50 per share
Trading Symbols	DNA.WS
Security Exchange Name	NYSE
Common Class B
Document Information [Line Items]
Entity Common Stock, Shares Outstanding		378,994,485
Nonvoting Common Stock
Document Information [Line Items]
Entity Common Stock, Shares Outstanding		120,000,000

Condensed Consolidated Balance

Condensed Consolidated Balance Sheets - USD ($) $ in Thousands		Sep. 30, 2023	Dec. 31, 2022
Current assets:
Cash and cash equivalents		$ 1,049,244	$ 1,315,792
Accounts receivable, net		61,897	80,907
Accounts receivable - related parties		1,246	1,558
Inventory, net		70	4,364
Prepaid expenses and other current assets		29,389	47,458
Total current assets		1,141,846	1,450,079
Property, plant, and equipment, net		201,595	314,773
Operating lease right-of-use assets		341,614	400,762
Investments		84,970	112,188
Equity method investments	[1]	1,120	1,543
Intangible assets, net		100,168	111,041
Goodwill		58,057	60,210
Other non-current assets		97,022	88,725
Total assets		2,026,392	2,539,321
Current liabilities:
Accounts payable		10,753	10,451
Deferred revenue (includes $1,394 and $10,309 from related parties)		42,762	47,817
Accrued expenses and other current liabilities		114,947	114,694
Total current liabilities		168,462	172,962
Non-current liabilities:
Deferred revenue, net of current portion (includes $124,621 and $131,188 from related parties)		170,011	174,767
Operating lease liabilities, non-current		403,662	413,256
Warrant liabilities		12,255	10,868
Other non-current liabilities		19,319	31,191
Total liabilities		773,709	803,044
Commitments and contingencies (Note 8)
Stockholders’ equity:
Preferred stock, $0.0001 par value; 200,000 shares authorized; none issued		0	0
Common stock, $0.0001 par value (Note 6)		198	190
Additional paid-in capital		6,334,218	6,136,378
Accumulated deficit		(5,078,834)	(4,397,659)
Accumulated other comprehensive loss		(2,899)	(2,632)
Total stockholders’ equity		1,252,683	1,736,277
Total liabilities and stockholders’ equity		$ 2,026,392	$ 2,539,321
[1]Equity method investments in Platform Ventures with a carrying value of zero as of September 30, 2023 and December 31, 2022 were excluded from the table.

Condensed Consolidated Balanc_2

Condensed Consolidated Balance Sheets (Parenthetical) - USD ($) $ in Thousands	3 Months Ended	9 Months Ended
	Sep. 30, 2023	Sep. 30, 2023	Dec. 31, 2022
Deferred revenue, from related parties	$ 42,762	$ 42,762	$ 47,817
Deferred revenue, net of current portion, from related parties	$ 170,011	$ 170,011	$ 174,767
Preferred stock, par value (in dollars per share)	$ 0.0001	$ 0.0001	$ 0.0001
Preferred stock, authorized (in shares)	200,000	200,000	200,000
Preferred stock, issued (in shares)	0	0	0
Common stock, par value (in dollars per share)	$ 0.0001	$ 0.0001	$ 0.0001
Total revenue	$ 55,430	$ 216,700
Related party
Deferred revenue, from related parties	1,394	1,394	$ 10,309
Deferred revenue, net of current portion, from related parties	124,621	124,621	$ 131,188
Total revenue	$ 8,727	$ 19,912

Condensed Consolidated Statemen

Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($) shares in Thousands, $ in Thousands		3 Months Ended			9 Months Ended
		Sep. 30, 2023	Sep. 30, 2022		Sep. 30, 2023	Sep. 30, 2022
Total revenue		$ 55,430	$ 66,398	[1]	$ 216,700	$ 379,421	[1]
Costs and operating expenses:
Research and development		156,662	261,460	[1]	463,583	875,095	[1]
General and administrative		82,028	435,221	[1]	295,802	1,308,416	[1]
Operating Lease, Impairment Loss		96,210	0		96,210	0
Total operating expenses		341,823	721,336	[1]	902,989	2,357,509	[1]
Loss from operations		(286,393)	(654,938)	[1],[2]	(686,289)	(1,978,088)	[1],[2]
Other (expense) income:
Interest income, net		15,020	6,380	[1]	43,914	8,821	[1]
Loss on equity method investments		0	(22,711)	[1]	(1,516)	(53,764)	[1]
Loss on investments		(36,324)	(1,758)	[1]	(44,815)	(39,981)	[1]
Change in fair value of warrant liabilities		1,891	(12,445)	[1]	(1,387)	96,099	[1],[3]
Gain on deconsolidation of subsidiaries		0	15,989	[1]	0	31,889	[1],[3]
Other income (expense), net		2,893	(676)	[1]	9,045	1,473	[1]
Total other (expense) income, net		(16,520)	(15,221)	[1]	5,241	44,537	[1]
Loss before income taxes		(302,913)	(670,159)	[1]	(681,048)	(1,933,551)	[1]
Income tax (benefit) provision		(22)	(28)	[1]	127	(257)	[1]
Net Loss		(302,891)	(670,131)	[1]	(681,175)	(1,933,294)	[1],[3]
Loss attributable to non-controlling interest		0	0	[1]	0	(3,833)	[1]
Net loss attributable to Ginkgo Bioworks Holdings, Inc. stockholders		$ (302,891)	$ (670,131)	[1]	$ (681,175)	$ (1,929,461)	[1]
Net loss per share attributable to Ginkgo Bioworks Holdings, Inc. common stockholders, basic (in dollars per share)		$ (0.16)	$ (0.41)	[1]	$ (0.35)	$ (1.19)	[1]
Net loss per share attributable to Ginkgo Bioworks Holdings, Inc. common stockholders, diluted (in dollars per share)		$ (0.16)	$ (0.41)	[1]	$ (0.35)	$ (1.19)	[1]
Weighted average common shares outstanding, basic (in shares)		1,950,814	1,630,911	[1]	1,933,202	1,619,790	[1]
Weighted average common shares outstanding, diluted (in shares)		1,950,814	1,630,911	[1]	1,933,202	1,619,790	[1]
Comprehensive loss:
Net loss		$ (302,891)	$ (670,131)	[1]	$ (681,175)	$ (1,933,294)	[1],[3]
Other comprehensive loss:
Foreign currency translation adjustment		(1,599)	(2,414)	[1]	(267)	(6,195)	[1]
Total other comprehensive loss		(1,599)	(2,414)	[1]	(267)	(6,195)	[1]
Comprehensive loss		(304,490)	(672,545)	[1]	(681,442)	(1,939,489)	[1]
Cell Engineering
Total revenue	[4]	37,176	24,679	[1]	116,555	90,409	[1]
Product
Total revenue		6,495	5,190	[1]	28,949	23,024	[1]
Costs and operating expenses:
Cost of Biosecurity revenue		906	2,660	[1]	7,481	13,199	[1]
Service
Total revenue		11,759	36,529	[1]	71,196	265,988	[1]
Costs and operating expenses:
Cost of Biosecurity revenue		$ 6,017	$ 21,995	[1]	$ 39,913	$ 160,799	[1]
[1] As adjusted to reflect the impact of the adoption of Accounting Standards Codification Topic 842, Leases (“ASC 842”) as of January 1, 2022. See Note 1 for a summary of the adjustments.

Condensed Consolidated Statem_2

Condensed Consolidated Statements of Changes in Shareholders' Equity - USD ($) $ in Thousands		Total		Adoption of ASC 842	Common Stock	Additional Paid-In Capital	Accumulated Deficit	Accumulated Deficit Adoption of ASC 842	Accumulated Other Comprehensive Loss	Non- Controlling Interest
Beginning balance (in shares) at Dec. 31, 2021					1,611,392,000
Beginning balance at Dec. 31, 2021		$ 1,567,379		$ 5,195	$ 161	$ 3,804,844	$ (2,297,925)	$ 5,195	$ (1,715)	$ 62,014
Issuance of common stock upon exercise or vesting of equity awards (in shares)					29,025,000
Issuance of common stock upon exercise or vesting of equity awards		123			$ 3	120
Tax withholdings related to net share settlement of equity awards (in shares)					(296,000)
Tax withholdings related to net share settlement of equity awards		(981)				(981)
Settlement of contingent consideration	[1]	0
Issuance of common stock for asset acquisition (in shares)					8,142,000
Issuance of common stock for asset acquisition		27,720			$ 1	27,719
Stock-based compensation expense and other		1,839,316				1,837,089				2,227
Foreign currency translation adjustment		(6,195)	[2]						(6,195)
Net loss		(1,933,294)	[2],[3]				(1,929,461)			(3,833)
Deconsolidation of subsidiaries		(55,408)								(55,408)
Ending balance (in shares) at Sep. 30, 2022	[4]				1,648,263,000
Ending balance at Sep. 30, 2022	[4]	1,443,855			$ 165	5,668,791	(4,222,191)		(7,910)	5,000
Beginning balance (in shares) at Jun. 30, 2022					1,635,634,000
Beginning balance at Jun. 30, 2022		1,572,251			$ 164	5,098,018	(3,552,060)		(5,496)	31,625
Issuance of common stock upon exercise or vesting of equity awards (in shares)					10,041,000
Issuance of common stock upon exercise or vesting of equity awards		45			$ 1	44
Issuance of common stock for asset acquisition (in shares)					2,588,000
Issuance of common stock for asset acquisition		7,592				7,592
Stock-based compensation expense and other		563,137				563,137				0
Foreign currency translation adjustment		(2,414)	[2]						(2,414)
Net loss		(670,131)	[2]				(670,131)
Deconsolidation of subsidiaries		(26,625)								(26,625)
Ending balance (in shares) at Sep. 30, 2022	[4]				1,648,263,000
Ending balance at Sep. 30, 2022	[4]	$ 1,443,855			$ 165	5,668,791	(4,222,191)		(7,910)	$ 5,000
Beginning balance (in shares) at Dec. 31, 2022		1,891,976,000			1,891,976,000
Beginning balance at Dec. 31, 2022		$ 1,736,277			$ 190	6,136,378	(4,397,659)		(2,632)
Issuance of common stock upon exercise or vesting of equity awards (in shares)					75,480,000
Issuance of common stock upon exercise or vesting of equity awards		539			$ 8	531
Tax withholdings related to net share settlement of equity awards (in shares)					(14,000)
Tax withholdings related to net share settlement of equity awards		(23)				(23)
Settlement of contingent consideration (in shares)					440,000
Settlement of contingent consideration		3,222				3,222
Issuance of common stock for asset acquisition (in shares)					2,820,000
Issuance of common stock for asset acquisition		3,581				3,581
Issuance of common stock in exchange for services (in shares)					2,023,000
Issuance of common stock in exchange for services		2,500				2,500
Stock-based compensation expense and other		188,029				188,029
Foreign currency translation adjustment		(267)							(267)
Net loss		$ (681,175)					(681,175)
Ending balance (in shares) at Sep. 30, 2023		1,972,725,000			1,972,725,000
Ending balance at Sep. 30, 2023		$ 1,252,683			$ 198	6,334,218	(5,078,834)		(2,899)
Beginning balance (in shares) at Jun. 30, 2023					1,954,704,000
Beginning balance at Jun. 30, 2023		1,503,585			$ 196	6,280,632	(4,775,943)		(1,300)
Issuance of common stock upon exercise or vesting of equity awards (in shares)					17,581,000
Issuance of common stock upon exercise or vesting of equity awards		55			$ 2	53
Settlement of contingent consideration (in shares)					440,000
Settlement of contingent consideration		960				960
Stock-based compensation expense and other		52,573				52,573
Foreign currency translation adjustment		(1,599)							(1,599)
Net loss		$ (302,891)					(302,891)
Ending balance (in shares) at Sep. 30, 2023		1,972,725,000			1,972,725,000
Ending balance at Sep. 30, 2023		$ 1,252,683			$ 198	$ 6,334,218	$ (5,078,834)		$ (2,899)
[1]As adjusted to reflect the impact of the adoption of ASC 842 as of January 1, 2022. See Note 1 for a summary of the adjustments.[2] As adjusted to reflect the impact of the adoption of Accounting Standards Codification Topic 842, Leases (“ASC 842”) as of January 1, 2022. See Note 1 for a summary of the adjustments.

Condensed Consolidated Statem_3

Condensed Consolidated Statement of Cash Flows - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2023	Sep. 30, 2022	[2]
Cash flows from operating activities:
Net loss	$ (681,175)	$ (1,933,294)	[1]
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	57,670	26,885
Stock-based compensation	187,047	1,822,472
Loss on investments and equity method investments	46,331	93,745
Change in fair value of warrant liabilities	1,387	(96,099)	[1]
Change in fair value of contingent consideration liability	10,217	58
Gain on deconsolidation of subsidiaries	0	(31,889)	[1]
Impairment of long-lived assets	121,404	0
Non-cash customer consideration	(884)	(18,139)
Non-cash lease expense	24,635	11,877
Non-cash in-process research and development	3,981	1,162
Other non-cash activity	3,937	4,602
Changes in operating assets and liabilities:
Accounts receivable ($312 and $4,598 from related parties)	21,168	20,521
Prepaid expenses and other current assets	13,557	5,230
Operating lease right-of-use assets	9,277	0
Other non-current assets	(2,733)	144
Accounts payable, accrued expenses and other current liabilities	(4,822)	(11,852)
Deferred revenue, current and non-current ($(15,482) and $(21,774) from related parties)	(29,382)	(35,365)
Operating lease liabilities, current and non-current	(18,310)	(7,807)
Other non-current liabilities	(974)	82
Net cash used in operating activities	(237,669)	(147,667)
Cash flows from investing activities:
Purchase of convertible note (related party)	0	(10,000)
Purchases of property and equipment	(37,355)	(26,626)
Proceeds from sale of equipment	3,000	110
Purchase of investment in equity securities	0	(3,691)
Deconsolidation of subsidiaries - cash	0	(55,721)
Other	336	(1,206)
Net cash used in investing activities	(34,019)	(97,134)
Cash flows from financing activities:
Principal payments on capital leases and lease financing obligation	(977)	(912)
Contingent consideration payment	(1,082)	(521)
Other	(525)	(993)
Net cash used in financing activities	(2,584)	(2,426)
Effect of foreign exchange rates on cash and cash equivalents	(690)	(191)
Net decrease in cash, cash equivalents and restricted cash	(274,962)	(247,418)
Cash and cash equivalents, beginning of period	1,315,792	1,550,004
Restricted cash, beginning of period	53,789	42,924
Cash, cash equivalents and restricted cash, beginning of period	1,369,581	1,592,928
Cash and cash equivalents, end of period	1,049,244	1,302,603
Restricted cash, end of period	45,375	42,907
Cash, cash equivalents and restricted cash, end of period	$ 1,094,619	$ 1,345,510
[1] As adjusted to reflect the impact of the adoption of Accounting Standards Codification Topic 842, Leases (“ASC 842”) as of January 1, 2022. See Note 1 for a summary of the adjustments.

Condensed Consolidated Statem_4

Condensed Consolidated Statement of Cash Flows (Parenthetical) - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2023	Sep. 30, 2022
Accounts receivable, from related parties	$ 21,168	$ 20,521	[1]
Deferred revenue, current and non-current, from related parties	(29,382)	(35,365)	[1]
Related party
Accounts receivable, from related parties	(312)	(4,598)
Deferred revenue, current and non-current, from related parties	$ (15,482)	$ (21,774)
[1]As adjusted to reflect the impact of the adoption of ASC 842 as of January 1, 2022. See Note 1 for a summary of the adjustments.

Basis of Presentation and Summa

Basis of Presentation and Summary of Significant Accounting Policies	9 Months Ended
	Sep. 30, 2023
Accounting Policies [Abstract]
Basis of Presentation and Summary of Significant Accounting Policies	Basis of Presentation and Summary of Significant Accounting Policies Business The mission of Ginkgo Bioworks Holdings, Inc. (“Ginkgo” or the “Company”) is to make biology easier to engineer. The Company designs custom cells for customers across multiple markets. Since inception, the Company has devoted its efforts to improving its platform for programming cells to enable customers to leverage biology to create impactful products across a range of industries. The Company’s platform comprises (i) equipment, robotic automation, software, data pipelines and tools, and standard operating procedures for high throughput genetic engineering, fermentation, and analytics (referred to collectively as the “Foundry”), (ii) a library of proprietary genetic assets and associated performance data (referred to collectively as “Codebase”), and (iii) the Company’s team of expert users, developers and operators of the Foundry and Codebase. With a mission to make biology easier to engineer, the Company has recognized the need to invest in biosecurity as a key component of its platform. The Company’s biosecurity and public health unit, Concentric by Ginkgo, is building a global infrastructure for biosecurity to empower governments, communities, and public health leaders to prevent, detect and respond to a wide variety of biological threats. Basis of Presentation The accompanying condensed consolidated financial statements have been prepared in conformity with the rules and regulations of the Securities and Exchange Commission and generally accepted accounting principles in the United States (“GAAP”) for interim financial reporting. Accordingly, certain detailed disclosures which would normally be included with annual financial statements have been omitted. In the opinion of management, all normal recurring adjustments necessary for a fair presentation have been made. These condensed consolidated financial statements should be read in conjunction with the Company's 2022 Annual Report on Form 10-K. Interim results are not necessarily indicative of results for a full year. Principles of Consolidation The accompanying condensed consolidated financial statements include the accounts of the Company, its wholly owned subsidiaries, majority owned subsidiaries and variable interest entities if the Company is the primary beneficiary. All intercompany accounts and transactions have been eliminated. Use of Estimates The preparation of financial statements in conformity with GAAP requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities, revenues and expenses, and the disclosure of contingent liabilities in the condensed consolidated financial statements. Estimates used in the preparation of these condensed consolidated financial statements include, among others, revenue recognition, stock-based compensation, the fair value of assets acquired and liabilities assumed in a business combination, the fair value of non-cash consideration received from customers, the fair value of certain notes receivable, the fair value of certain investments including equity method investments, the fair value of warrant liabilities, the allocation of equity method investment losses under the hypothetical liquidation at book value (“HLBV”) method, the incremental borrowing rate used in determining lease liabilities, impairment of long-lived assets, allowance for credit losses, accrued expenses and income taxes. The Company bases its estimates on historical experience and other market-specific or relevant assumptions that it believes to be reasonable under the circumstances. Reported amounts and disclosures reflect the overall economic conditions that management believes are most likely to occur, and the anticipated measures management intends to take. Actual results could differ materially from those estimates. All revisions to accounting estimates are recognized in the period in which the estimates are revised. Significant Accounting Policies There have been no new or material changes to the Company’s significant accounting policies during the nine months ended September 30, 2023 as compared to the significant accounting policies described in Note 2 to the Company's 2022 consolidated financial statements included in the 2022 Annual Report on Form 10-K. Retrospective Application of a Change in Accounting Principle The Company adopted Accounting Standards Update No. 2016-02, Leases (“ASC 842”), which supersedes the guidance in Accounting Standards Codification Topic 840, Leases (“ASC 840”), effective January 1, 2022. As the Company elected the extended transition period for complying with new or revised accounting standards pursuant to Section 107(b) of the Jumpstart Our Business Startups Act of 2012, ASC 842 was adopted in connection with the preparation of the Company’s annual consolidated financial statements as of and for the year ended December 31, 2022. As such, the comparative information for the three and nine months ended September 30, 2022 has been adjusted herein to reflect the impact of the adoption of ASC 842 as of January 1, 2022. Select line items from the condensed consolidated statement of operations and comprehensive loss reflecting the adoption of ASC 842 are as follows (in thousands): Three Months Ended September 30, 2022 Nine Months Ended September 30, 2022 As Previously Reported Adjustments As Adjusted As Previously Reported Adjustments As Adjusted Costs and operating expenses: Research and development $ 259,580 $ 1,880 $ 261,460 $ 871,488 $ 3,607 $ 875,095 General and administrative 435,184 37 435,221 1,308,379 37 1,308,416 Total operating expenses 719,419 1,917 721,336 2,353,865 3,644 2,357,509 Loss from operations (653,021) (1,917) (654,938) (1,974,444) (3,644) (1,978,088) Other (expense) income: Interest income, net 5,820 560 6,380 7,097 1,724 8,821 Other income (expense), net (957) 281 (676) 629 844 1,473 Total other (expense) income, net (16,062) 841 (15,221) 41,969 2,568 44,537 Loss before income taxes (669,083) (1,076) (670,159) (1,932,475) (1,076) (1,933,551) Net loss (669,055) (1,076) (670,131) (1,932,218) (1,076) (1,933,294) Net loss attributable to Ginkgo Bioworks Holdings, Inc. stockholders (669,055) (1,076) (670,131) (1,928,385) (1,076) (1,929,461) Select line items from the condensed consolidated statements of stockholders’ equity reflecting the adoption of ASC 842 are as follows (in thousands): As of September 30, 2022 As Previously Reported Adjustments As Adjusted Accumulated deficit $ (4,226,310) $ 4,119 $ (4,222,191) Total stockholders' equity 1,439,736 4,119 1,443,855 Select line items from the condensed consolidated statements of cash flows reflecting the adoption of ASC 842 are as follows (in thousands): Nine Months Ended September 30, 2022 As Previously Reported Adjustments As Adjusted Cash flows from operating activities: Adjustments to reconcile net loss to net cash used in operating activities: Depreciation and amortization $ 28,602 $ (1,717) $ 26,885 Amortization of finance lease right-of-use assets (1) — 1,535 1,535 Non-cash lease expense — 11,877 11,877 Changes in operating assets and liabilities: Prepaid expenses and other current assets 5,849 (619) 5,230 Accounts payable, accrued expenses and other current liabilities (11,744) (108) (11,852) Operating lease liabilities, current and non-current — (7,807) (7,807) Deferred rent, non-current 2,255 (2,255) — Cash flows from financing activities: Principal payments on finance leases — (912) (912) Principal payments on capital leases and lease financing obligation (1,082) 1,082 — (1) Presented in other non-cash activity Recently Issued Accounting Pronouncements There were no new recently issued accounting pronouncements that are of significance or potential significance to the Company from those disclosed herein and within Note 2 to the Company's 2022 consolidated financial statements included in the 2022 Annual Report on Form 10-K.

Business Combination

Business Combination	9 Months Ended
	Sep. 30, 2023
Business Combination and Asset Acquisition [Abstract]
Business Combination	Business Combination On April 1, 2022, the Company acquired all of the outstanding equity interests of FGen AG (“FGen”), a company organized under the laws of Switzerland that specializes in strain development and optimization and has developed an ultra-high-throughput screening platform. The Company accounted for the transaction as a business combination under ASC 805, Business Combinations . The consideration paid was comprised of common stock and contingent consideration as follows (in thousands): Fair value of Class A common stock $ 17,015 Fair value of contingent consideration - restricted stock 3,842 Fair value of contingent consideration - milestones 8,464 Total FGen consideration $ 29,321 The Company issued 5.7 million shares of its Class A common stock on the acquisition date comprised of 4.0 million unrestricted shares valued at $17.0 million based on the closing market price of $4.20 per share and 1.7 million restricted shares classified as contingent consideration and subject to vesting conditions. Of the restricted shares, 0.6 million shares were subsequently forfeited during the quarter ended June 30, 2022 when the contingency related to the filing of a registration statement was resolved. The Company incurred $1.7 million of acquisition-related costs which were included in general and administrative expenses in the condensed consolidated statements of operations and comprehensive loss for the nine months ended September 30, 2022. The following table presents the final allocation of the purchase price to the assets acquired and liabilities assumed as of the acquisition date (in thousands): Final Allocation Cash and cash equivalents $ 1,430 Accounts receivable 144 Other non-current assets 10 Property and equipment 34 Intangible assets (1) 21,100 Goodwill (2) 10,615 Accounts payable and accrued expenses (29) Deferred revenue (104) Deferred tax liability (3,879) Net assets acquired $ 29,321 (1) Estimated useful life of 15 years.

Fair Value Measurements

Fair Value Measurements	9 Months Ended
	Sep. 30, 2023
Fair Value Disclosures [Abstract]
Fair Value Measurements	Fair Value Measurements The following tables present information about the Company’s financial assets and liabilities measured at fair value on a recurring basis (in thousands): As of September 30, 2023 Classification Total Level 1 Level 2 Level 3 Assets: Money market funds Cash and cash equivalents $ 1,019,232 $ 1,019,232 $ — $ — Synlogic, Inc. warrants (1) Investments 477 — 477 — Marketable equity securities (2) Investments 20,148 18,842 1,306 — Loan receivable Prepaid expenses and other current assets 100 — — 100 Notes receivable Other non-current assets 39,860 — 30,000 9,860 Total assets $ 1,079,817 $ 1,038,074 $ 31,783 $ 9,960 Liabilities: Public Warrants Warrant liabilities $ 7,934 $ 7,934 $ — $ — Private Placement Warrants (3) Warrant liabilities 4,321 — 125 4,196 Contingent consideration Accrued expenses and other current liabilities 23,838 — — 23,838 Contingent consideration Other non-current liabilities 7,488 — — 7,488 Total liabilities $ 43,581 $ 7,934 $ 125 $ 35,522 As of December 31, 2022 Classification Total Level 1 Level 2 Level 3 Assets: Money market funds Cash and cash equivalents $ 1,089,026 $ 1,089,026 $ — $ — Synlogic, Inc. warrants (1) Investments 1,937 — 1,937 — Marketable equity securities (2) Investments 25,714 21,312 4,402 — Notes receivable Other non-current assets 37,660 — 30,000 7,660 Total assets $ 1,154,337 $ 1,110,338 $ 36,339 $ 7,660 Liabilities: Public Warrants Warrant liabilities $ 6,900 $ 6,900 $ — $ — Private Placement Warrants (3) Warrant liabilities 3,968 — 108 3,860 Contingent consideration Accrued expenses and other current liabilities 6,378 — — 6,378 Contingent consideration Other non-current liabilities 18,095 — — 18,095 Total liabilities $ 35,341 $ 6,900 $ 108 $ 28,333 (1) The fair value of Synlogic, Inc. warrants is calculated as the quoted price of the underlying common stock, less the unpaid exercise price of the warrants. (2) Marketable equity securities classified as Level 2 reflect a discount for lack of marketability due to regulatory sales restrictions. (3) The fair value of Private Placement Warrants classified as Level 2 is equivalent to that of Public Warrants as the transfer of Private Placement Warrants to anyone other than the initial purchasers or any of their permitted transferees results in the Private Placement Warrants having substantially the same terms as the Public Warrants. Transfers to/from Levels 1, 2 and 3 are recognized at the end of the reporting period in which a change in valuation technique or methodology occurs. Transfers from Level 2 to Level 1 during the nine months ended September 30, 2022 were due to a lapse on regulatory sales restrictions on marketable equity securities. There were no other transfers to/from Levels 1, 2, or 3 during the nine months ended September 30, 2023 and 2022. Notes Receivable The Company has elected the fair value option under ASC 825, Financial Instruments , to account for its notes receivable. Notes receivable accounted for under the fair value option are marked to market as of each balance sheet date with changes in fair value recorded in other income (expense), net in the condensed consolidated statements of operations and comprehensive loss. As of September 30, 2023 and December 31, 2022, notes receivable measured at fair value on a recurring basis primarily consisted of a $30.0 million senior secured note (“Senior Secured Note”) purchased from Bolt Threads, Inc. and a series of convertible promissory notes issued by customers as payment for Cell Engineering services. The Company used the yield method to value the Senior Secured Note. Under this method, the estimated future cash flows, consisting of principal and interest payments, are discounted to present value using an applicable market yield or discount rate. Increases or decreases in the market yield or discount rate would result in a decrease or increase, respectively, in the fair value measurement. The market yield is determined using a corporate bond yield curve corresponding to the credit rating category of the issuer. The fair value of the Senior Secured Note is based on observable market inputs, which represents a Level 2 measurement within the fair value hierarchy. The Company used a scenario-based method to value the series of convertible promissory notes from customers. Under the scenario-based method, future cash flows are evaluated under qualified financing, maturity and dissolution scenarios, probability-weighted, and discounted to present value. The significant unobservable (Level 3) inputs used in the fair value measurement as of September 30, 2023 were scenario probabilities of 15% to 55%, a discount rate of 17% and estimated time to event date of one as of December 31, 2022 were scenario probabilities of 15% to 55%, a discount rate of 12.5% and estimated time to event date of one The following table provides a reconciliation of notes and loans receivable measured at fair value using Level 3 significant unobservable inputs for the nine months ended September 30 (in thousands): 2023 2022 Balance at January 1, $ 7,660 $ 11,559 Additions 4,106 — Change in fair value (1,806) 269 Balance at September 30, $ 9,960 $ 11,828 Warrant Liabilities In connection with the Company's merger with Soaring Eagle Acquisition Corp. (“SRNG”) on September 16, 2021, the Company assumed 34.5 million publicly-traded warrants (“Public Warrants”) and 17.3 million private placement warrants (the “Private Placement Warrants”) previously issued in connection with SRNG’s initial public offering. The fair value of the Public Warrants is based on the observable quoted price of such warrants on the New York Stock Exchange. The fair value of the Private Placement Warrants is estimated using the Black-Scholes option pricing model, which is considered to be a Level 3 fair value measurement. The primary unobservable input used in the valuation of the Private Placement Warrants is expected stock-price volatility. The Company estimated the volatility of its Private Placement Warrants using a Monte-Carlo simulation of the redeemable Public Warrants that assumes optimal exercise of the Company's redemption option at the earliest possible date. The risk-free interest rate is based on the U.S. Treasury zero-coupon yield curve for a maturity similar to the expected remaining life of the warrants. The expected life of the warrants is assumed to be equivalent to their remaining contractual term. The dividend yield is based on the historical rate, which the Company anticipates remaining at zero. The following table provides quantitative information regarding Level 3 inputs used in the recurring valuation of the Private Placement Warrants as of their measurement dates: September 30, 2023 December 31, 2022 Exercise price $ 11.50 $ 11.50 Stock price $ 1.81 $ 1.69 Volatility 79.0 % 71.5 % Term (in years) 2.96 3.71 Risk-free interest rate 4.83 % 4.11 % The following table provides a reconciliation of the Private Placement Warrants measured at fair value using Level 3 significant unobservable inputs for the nine months ended September 30 (in thousands): 2023 2022 Balance at January 1, $ 3,860 $ 58,558 Change in fair value 336 (43,658) Balance at September 30, $ 4,196 $ 14,900 Contingent Consideration In connection with the acquisition of FGen in April 2022, the Company is required to make contingent earnout payments up to $20.0 million primarily related to the successful integration and deployment of the FGen technology across the Company's programs. In connection with the acquisition of Dutch DNA Biotech B.V. (“Dutch DNA”) in July 2021, the Company is required to make contingent earnout payments up to a maximum of $20.0 million payable upon the achievement of certain technical and commercial milestones by Dutch DNA pursuant to a Technical Development Agreement executed between the Company and Dutch DNA prior to the close of the acquisition. In connection with the acquisition of Circularis Biotechnologies, Inc., (“Circularis”) in October 2022, the Company is required to make contingent earnout payments up to a maximum of $37.5 million payable primarily upon the achievement of certain clinical trial milestones over a five-year period, $2.5 million of which was achieved in October 2023. In connection with the acquisition of Altar SAS (“Altar”) in October 2022, the Company is required to make contingent earnout payments up to $2.5 million upon the successful transfer of the Altar technology to Ginkgo's sites in the U.S. The Company also issued restricted stock related to acquisitions that is subject to vesting conditions and is classified as contingent consideration liability. The fair value of contingent consideration related to restricted stock was estimated using the quoted price of Ginkgo's Class A common stock, an estimate of the number of shares expected to vest, probability of vesting, and a discount rate. The fair value of contingent consideration related to earnout payments from acquisitions was estimated using unobservable (Level 3) inputs as illustrated in the table below. Material increases or decreases in these inputs could result in a higher or lower fair value measurement. Changes in the fair value of contingent consideration are recorded in general and administrative expense in the condensed consolidated statements of operations and comprehensive loss. The Company can settle all contingent consideration liabilities, other than those related to the Dutch DNA acquisition, in cash or shares of Class A common stock at the Company’s election. During the nine months ended September 30, 2023, the Company settled $4.8 million in contingent consideration liabilities through payment of $1.5 million in cash and vesting of 1.6 million shares of restricted stock valued at $3.2 million. Of that amount, $1.4 million related to the Circularis asset acquisition was recorded as an increase to the acquired intangible asset with an offset to additional paid-in-capital as the contingent consideration liability was deemed not probable until the filing of a registration statement. The following table provides quantitative information regarding Level 3 inputs used in the fair value measurements of contingent consideration liabilities as of the periods presented: September 30, 2023 December 31, 2022 Contingent Consideration Liability Valuation Technique Unobservable Input Range Range Earnout payments (FGen, Dutch DNA, Circularis and Altar acquisitions) Probability-weighted present value Probability of payment 10% - 100% 2% - 100% Discount rate 14.5% - 15.3% 12.2% - 13.1% Earnout payments (Dutch DNA acquisition) Discounted cash flow Projected years of payments 2025 - 2028 2025 - 2028 Discount rate 11.5 % 12.0 % The following table provides a reconciliation of the contingent consideration measured at fair value using Level 3 significant unobservable inputs for the nine months ended September 30 (in thousands): 2023 2022 Balance at January 1, $ 24,473 $ 8,467 Additions 1,397 13,150 Change in fair value 10,217 58 Settlements and payments (4,761) (2,644) Balance at September 30, $ 31,326 $ 19,031 Nonrecurring Fair Value Measurements The Company measures the fair value of certain assets, including investments in privately held companies without readily determinable fair values, on a nonrecurring basis when events or changes in circumstances indicate that the carrying amount of the assets may not be recoverable and when there are observable price changes for the identical or similar security of the same issuer. The fair value of non-marketable equity securities is classified within Level 3 in the fair value hierarchy when the Company estimates fair value using unobservable inputs to measure the amount of the impairment loss. The fair value of non-marketable equity securities is classified within Level 2 in the fair value hierarchy when the Company estimates fair value using the observable transaction price paid by third party investors for the identical or similar security of the same issuer. During the three and nine months ended September 30, 2023, the Company recorded a $33.0 million impairment loss related to its investment in Genomatica preferred stock. The fair value measurement was determined using the guideline public company method under the market approach. The significant unobservable inputs used in the valuation included the selection and analysis of guideline public companies, revenue multiple and other unobservable assumptions. Additionally, during the three and nine months ended September 30, 2023, the Company recorded a $1.6 million downward adjustment from an observable price change related to one of its investments in non-marketable equity securities. During the nine months ended September 30, 2023, the Company received $11.0 million in Simple Agreement for Future Equity arrangements (“SAFEs”) from customers as prepayment for Cell Engineering services. The Company used a scenario-based method to value the SAFEs at contract inception, which resulted in a total fair value of $4.5 million. Under the scenario-based method, future cash flows were evaluated under qualified financing and dissolution scenarios with partial recovery and no recovery in dissolution. The cash flows under each scenario were probability-weighted and discounted to present value. The significant unobservable inputs used in the fair value measurement were scenario probabilities of 20% to 60%, a discount rate of 14% and estimated time to event date of one During the nine months ended September 30, 2023, the Company recorded a $1.8 million impairment loss related to a SAFE to write-down its carrying amount to its estimated fair value. The fair value measurement of the impairment loss was determined using the scenario-based method, whereby dissolution scenarios with partial recovery and no recovery were probability weighted 15% and 85%, respectively, and discounted to present value using a discount rate of 14%.

Investments and Equity Method I

Investments and Equity Method Investments	9 Months Ended
	Sep. 30, 2023
Equity Method Investments and Joint Ventures [Abstract]
Investments and Equity Method Investments	Investments and Equity Method Investments The Company partners with other investors to form business ventures, including Motif FoodWorks, Inc. (“Motif”), Allonnia, LLC (“Allonnia”), Arcaea, LLC (“Arcaea”), Verb Biotics, LLC (“Verb”), BiomEdit, LLC (“BiomEdit”) and Ayana Bio, LLC (“Ayana”) (collectively “Platform Ventures”). The Company also partners with existing entities, including Genomatica, Inc. (“Genomatica”) and Synlogic, Inc. (“Synlogic”) (collectively, “Legacy Structured Partnerships”) with complementary assets for high potential synthetic biology applications. The Company holds equity interests in these Platform Ventures and Structured Partnerships. The Company also holds equity interests in other public and private companies as a result of entering into collaboration and license revenue arrangements with these entities. The Company accounts for its investments in Platform Ventures under the equity method. The Company's marketable equity securities consist of Synlogic common stock, Synlogic warrants and the shares of common stock of other publicly traded companies. Marketable equity securities are measured at fair value with changes in fair value recorded in other (expense) income in the condensed consolidated statements of operations and comprehensive loss. The Company’s non-marketable equity securities consist of preferred stock of Genomatica and preferred and common stock of other privately held companies without readily determinable fair values. Non-marketable equity securities are initially recorded using the measurement alternative at cost and subsequently adjusted for any impairment and observable price changes in orderly transactions for the identical or a similar security of the same issuer. The Company recorded a $33.0 million impairment loss related to its investment in Genomatica for the three and nine months ended September 30, 2023, and a $10.1 million impairment loss related to its investment in Genomatica for the nine months ended September 30, 2022. During the three and nine months ended September 30, 2023, the Company recorded a $1.6 million downward adjustment from an observable price change related to its investments in non-marketable equity securities. There were no adjustments from observable price changes during the three and nine months ended September 30, 2022. Impairment losses and adjustments from observable price changes are recorded in loss on investments in the condensed consolidated statements of operations and comprehensive loss. The Company also holds investments in early-stage synthetic biology product companies via SAFEs. The Company enters into SAFE agreements in conjunction with a revenue contract with a customer under which the Company grants the customer a prepaid Cell Engineering services credit equal to the principal amount of the SAFE (the “Purchase Amount”), which may be used and drawn down as payment for the Company’s research and development services. The SAFEs will automatically convert into shares of preferred stock equal to the Purchase Amount divided by the discount price, which is calculated as the price per share sold in a qualified equity financing multiplied by a discount rate. The SAFEs also provide the Company with the right to future equity of the entity in a liquidation scenario or the cash-out amount in liquidation and dissolution scenarios or at the election of the SAFE issuer prior to an agreed outside date. The Company initially records SAFEs at fair value (see Note 3) and adjusts the carrying amount of the instrument at each reporting period for any impairment, plus or minus changes resulting from observable price changes in orderly transactions for an identical or similar instrument of the same issuer. During the nine months ended September 30, 2023, the Company recorded a $1.8 million impairment charge related to SAFEs, included as a component of loss on investments in the condensed consolidated statements of operations and comprehensive loss. There was no impairment recorded during the three or nine months ended September 30, 2022 and no adjustments from observable price changes during any of the periods presented. Investments and equity method investments consisted of the following (in thousands): As of September 30, As of December 31, 2023 2022 Investments: Genomatica, Inc. preferred stock $ 11,885 $ 44,885 Synlogic, Inc. common stock 1,188 4,819 Synlogic, Inc. warrants 477 1,937 Marketable equity securities 18,960 20,895 Non-marketable equity securities 27,631 17,544 SAFEs 24,829 22,108 Total $ 84,970 $ 112,188 Equity method investments (1) : BiomEdit, LLC $ — $ 369 Other 1,120 1,174 Total $ 1,120 $ 1,543 (1) Equity method investments in Platform Ventures with a carrying value of zero as of September 30, 2023 and December 31, 2022 were excluded from the table. (Losses) gains on investments and equity method investments consisted of the following (in thousands): Three Months Ended September 30, Nine Months Ended September 30, 2023 2022 2023 2022 (Loss) gain on investments: Synlogic, Inc. common stock $ (1,538) $ (1,268) $ (3,631) $ (9,321) Synlogic, Inc. warrants (618) (510) (1,459) (3,746) Genomatica, Inc. (33,000) — (33,000) (10,115) Marketable equity securities 460 215 (3,286) (16,604) Non-marketable equity securities (1,628) (195) (1,628) (195) SAFEs — — (1,811) — Total $ (36,324) $ (1,758) $ (44,815) $ (39,981) Loss on equity method investments: Joyn Bio, LLC $ — $ (5,226) $ — $ (15,637) Verb Biotics, LLC — — — (15,900) BiomEdit, LLC — (1,308) (1,462) (5,860) Ayana, LLC — (15,989) — (15,989) Other — (188) (54) (378) Total $ — $ (22,711) $ (1,516) $ (53,764)

Variable Interest Entities

Variable Interest Entities	9 Months Ended
	Sep. 30, 2023
Variable Interest Entity, Measure of Activity [Abstract]
Variable Interest Entities	Variable Interest Entities Consolidated Variable Interest Entity The Company consolidated Cooksonia, LLC (“Cooksonia”), a variable interest entity (“VIE”) formed by the Company and certain other investors for the purposes of holding the Company’s investment in the Joyn Bio, LLC (“Joyn Bio”) joint venture, prior to the joint venture's termination in the fourth quarter of 2022. The Company concluded that it held a variable interest in and was the primary beneficiary of Cooksonia as it controlled the most significant activities of Cooksonia by controlling 100% of the board of directors of Cooksonia and held a controlling financial interest in Cooksonia. Unconsolidated Variable Interest Entities During the nine months ended September 30, 2022, Verb and Ayana each hired a new chief executive officer who was not an affiliate, related party or agent of Ginkgo. The respective chief executive officer was also appointed to each entity's joint steering committee (“JSC”) and board of directors. As a result, the Company concluded it no longer had substantive control of each entity's JSC and board of directors. Accordingly, the Company concluded that it was no longer the primary beneficiary of Verb and Ayana as it no longer controlled the most significant activities of the entities. As a result of this change in the primary beneficiary determination, the Company deconsolidated Verb in the first quarter of 2022 and Ayana in the third quarter of 2022 and recorded a gain on deconsolidation of $16.0 million and $31.9 million for the three and nine months ended September 30, 2022, respectively, in the condensed consolidated statements of operations and comprehensive loss. The gain on deconsolidation was equal to the fair value of the retained interest in each entity as of the deconsolidation date and was calculated using the option pricing method. The option pricing method used a back-solve methodology to infer the total equity value based on the pricing of the Series A preferred unit financing, which is the most recent financing transaction to the deconsolidation event. As of September 30, 2023 and December 31, 2022, the Company has concluded that its investments in Motif, Allonnia, Genomatica, Arcaea, BiomEdit, Verb and Ayana (collectively, the “Unconsolidated VIEs”) represent variable interests and that these entities are VIEs. Although the Company may have board representation and is involved in the ongoing development activities of the entities via its participation on the JSC, the Company has concluded that it is not the primary beneficiary of these entities. This conclusion is supported by the fact that: (i) the Company does not control the board of directors of any of the Unconsolidated VIEs, and no voting or consent agreements exist between the Company and other members of each respective board of directors or other investors, (ii) the holders of preferred security interests in the Unconsolidated VIEs hold certain rights that require their consent prior to taking certain actions, which include certain significant operating and financing decisions, and (iii) the Company’s representation on the JSC of each respective entity does not give it control over the development activities of any of the Unconsolidated VIEs, as all JSC decisions are made by consensus and there are no agreements in place that would require any of the entities to vote in alignment with the Company. As the Company’s involvement in the Unconsolidated VIEs does not give it the power to control the decisions with respect to their development or other activities, which are their most significant activities, the Company has concluded that it is not the primary beneficiary of the Unconsolidated VIEs. Additionally, the Company holds equity interests in certain privately-held companies that are not consolidated as the Company is not the primary beneficiary. As of September 30, 2023 and December 31, 2022, the maximum risk of loss related to the Company’s unconsolidated VIEs was limited to the carrying value of its investments in such entities.

Supplemental Financial Informat

Supplemental Financial Information	9 Months Ended
	Sep. 30, 2023
Supplemental Financial Statement Information [Abstract]
Supplemental Financial Information	Supplemental Financial Information Cash, Cash Equivalents and Restricted Cash The reconciliation of cash, cash equivalents and restricted cash reported within the condensed consolidated balance sheet to the totals shown within the condensed consolidated statement of cash flows is as follows (in thousands): As of September 30, 2023 2022 Cash and cash equivalents $ 1,049,244 $ 1,302,603 Restricted cash included in prepaid expenses and other current assets (1) 3,347 6,594 Restricted cash included in other non-current assets (1) 42,028 36,313 Total cash, cash equivalents and restricted cash $ 1,094,619 $ 1,345,510 (1) Includes cash balances collateralizing letters of credit associated with the Company’s facility leases and a customer prepayment requiring segregation and restrictions in its use in accordance with the customer agreement. Property, Plant, and Equipment, net Property, plant, and equipment, net consisted of the following (in thousands): As of September 30, As of December 31, 2023 2022 Lab equipment $ 147,043 $ 183,292 Leasehold improvements 83,177 125,307 Buildings and facilities 46,927 46,019 Construction in progress 15,099 23,426 Computer equipment and software 15,538 15,219 Furniture and fixtures 8,463 8,206 Land 6,060 6,060 Total property, plant, and equipment 322,307 407,529 Less: Accumulated depreciation and amortization (120,712) (92,756) Property, plant, and equipment, net $ 201,595 $ 314,773 During the three and nine months ended September 30, 2023, the Company identified excess lab equipment at two of its facilities whereby the assets were sold, classified as held for sale or otherwise impaired, resulting in aggregate impairment losses of $16.2 million and $25.2 million for the three and nine months ended September 30, 2023, respectively, included in general and administrative expense in the condensed consolidated statement of operations and comprehensive loss. Exit of a Leased Facility In September 2023, Zymergen Inc. (“Zymergen”) ceased the use of and exited a leased facility consisting of approximately 300,000 square feet of office and laboratory space in Emeryville, California. The facility was used pursuant to an operating lease with a minimum term expiring in August 2033. Zymergen's ceasing to use the space resulted in an impairment loss of $96.2 million, including $36.6 million for the right-of-use asset and $59.6 million for the related leasehold improvements. The impairment loss represents the amount by which the carrying value of the assets exceed their estimated fair values as of September 30, 2023, as determined using a discounted cash flow model under the income approach. The fair value measurements are based on significant inputs not observable in the market and therefore represent Level 3 fair value measurements. The key inputs used in the valuation were estimated sublease rental income and a discount rate of 8.5%. The impairments are presented as impairment of lease assets in the condensed consolidated statement of operations and comprehensive loss for the three and nine months ended September 30, 2023. Capitalization The following table presents the Company’s authorized, issued, and outstanding common stock as of the dates indicated (in thousands): Authorized Issued Outstanding Common stock as of September 30, 2023: Class A 10,500,000 1,612,729 1,497,104 Class B 4,500,000 379,141 355,621 Class C 800,000 120,000 120,000 15,800,000 2,111,870 1,972,725 Common stock as of December 31, 2022: Class A 10,500,000 1,448,234 1,337,499 Class B 4,500,000 383,649 354,477 Class C 800,000 200,000 200,000 15,800,000 2,031,883 1,891,976 On April 3, 2023, the Company issued 2.8 million shares of its Class A common stock as purchase consideration for the acquisition of StrideBio, Inc. (“StrideBio”) (see Note 8). On May 9, 2023, the Company issued 2.0 million shares of its Class A common stock, valued at approximately $2.5 million, as settlement for employee retention payments associated with the FGen acquisition. Refer to Note 9, Stock-Based Compensation, for shares of common stock issued in relation to the Company’s equity incentive plans. Changes in the number of shares of Class C common stock issued and outstanding represent an exchange of Class C common stock for the same number of shares of Class A common stock pursuant to a stockholder exchange agreement. Supplemental cash flow information The following table presents non-cash investing and financing activities (in thousands): Nine Months Ended September 30, 2023 2022 (as adjusted)* Supplemental disclosure of non-cash investing and financing activities: ROU Asset obtained in exchange for new operating lease liabilities upon adoption of ASC 842 $ — $ 147,744 ROU Asset obtained in exchange for new finance lease liabilities upon adoption of ASC 842 — 3,397 ROU Asset obtained in exchange for new operating lease liabilities 13,770 75,198 ROU Asset obtained in exchange for new finance lease liabilities — 1,370 Purchases of property and equipment included in accounts payable and accrued expenses 1,563 7,959 Equity received in related parties — 8,873 Convertible financial instruments received for Cell Engineering services 5,595 13,689 Equity securities and warrants received for Cell Engineering services 13,843 3,423 Settlement of contingent consideration 3,222 — Common stock issued for business and asset acquisitions 3,581 24,607 Contingent consideration for business acquisition — 13,150 Deferred offering and acquisition costs in accounts payable and accrued expenses — 1,660 * As adjusted to reflect the impact of the adoption of ASC 842 as of January 1, 2022. See Note 1 for a summary of the adjustments.

Goodwill and Intangible Assets,

Goodwill and Intangible Assets, net	9 Months Ended
	Sep. 30, 2023
Goodwill and Intangible Assets Disclosure [Abstract]
Goodwill and Intangible Assets, net	Goodwill and Intangible Assets, net All goodwill is allocated to the Cell Engineering reporting unit and segment identified in Note 11. Changes in the carrying amount of goodwill consisted of the following (in thousands): Balance as of December 31, 2022 $ 60,210 Impact of foreign currency translation (180) Measurement period adjustments (1,973) Balance as of September 30, 2023 $ 58,057 During the nine months ended September 30, 2023, the Company recognized a measurement period adjustment related to the Zymergen acquisition, which resulted in a decrease to goodwill of $2.2 million, an increase to accounts receivable of $1.8 million, and a decrease to accrued expenses and other current liabilities of $0.4 million. The adjustment was a result of updated information about facts and circumstances that existed at the acquisition date regarding the collectability of an acquired accounts receivable and accrued expenses under a collaboration agreement. Additionally, $0.2 million was added to goodwill related to the Altar SAS acquisition. Intangible assets, net consisted of the following (in thousands): Gross Carrying Value (1) Accumulated Amortization (1) Net Weighted Average September 30, 2023: Developed technology $ 117,107 $ (20,341) $ 96,766 8.8 Database 3,700 (503) 3,197 6.0 Customer relationships 380 (214) 166 0.9 Assembled workforce 190 (151) 39 0.4 Total intangible assets $ 121,377 $ (21,209) $ 100,168 December 31, 2022: Developed technology $ 115,824 $ (8,825) $ 106,999 9.4 Database 3,700 (107) 3,593 6.8 Customer relationships 380 (71) 309 1.6 Assembled workforce 190 (50) 140 1.0 Total intangible assets $ 120,094 $ (9,053) $ 111,041 (1) Gross carrying value and accumulated amortization include the impact of cumulative foreign currency translation adjustments. Amortization expense was $4.0 million and $1.0 million for the three months ended September 30, 2023 and 2022, respectively, and $12.2 million and $2.3 million for the nine months ended September 30, 2023 and 2022, respectively. As of September 30, 2023, estimated future amortization expense for identifiable intangible assets is as follows (in thousands): Remainder of 2023 $ 3,938 2024 15,561 2025 15,437 2026 15,437 2027 12,362 Thereafter 37,433 Total $ 100,168

Commitments and Contingencies

Commitments and Contingencies	9 Months Ended
	Sep. 30, 2023
Commitments and Contingencies Disclosure [Abstract]
Commitments and Contingencies	Commitments and Contingencies Purchase Obligations On August 29, 2023, the Company entered into a five-year strategic cloud and artificial intelligence (“AI”) partnership with Google Cloud, intended to enable the Company to develop and deploy AI tools for biology and biosecurity. The partnership includes minimum annual commitments to purchase cloud hosting services in exchange for various discounts on such services. The minimum annual commitments are as follows: year 1, $8.0 million; year 2, $28.0 million; year 3, $54.0 million; year 4, $86.0 million; and year 5, $113.0 million. The minimum commitments may be terminated by the Company upon payment of a cancellation fee representing a percentage of the remaining purchase commitment. The Company also entered into an agreement pursuant to which Google Cloud will provide up to $56.3 million in cash funding upon the Company’s achievement of certain milestones, which are expected over the next three years. The net service costs under the arrangement are recorded as research and development expenses in the accompanying condensed consolidated statements of operations and comprehensive loss for the three and nine months ended September 30, 2023. As of September 30, 2023, the remaining aggregate commitment was $289.0 million. Contingent Consideration Related to Asset Acquisitions On April 5, 2023, the Company entered into an Asset Purchase Agreement (“APA”) with StrideBio to acquire StrideBio's adeno-associated virus capsid discovery and engineering platform assets, with a secondary close contingent upon the transfer of certain additional in-license agreements to Ginkgo. The Company accounted for the transaction as an asset acquisition as substantially all of the fair value of the assets acquired is concentrated in a single identifiable asset. The fair value of the consideration transferred totaled $4.0 million and consisted of 2.8 million shares of Ginkgo's Class A common stock valued at $3.6 million and a $0.4 million contingent holdback, all of which was expensed as in-process research and development during the nine months ended September 30, 2023. In October 2023, the Company completed the secondary closing for an additional purchase price of $3.8 million, which was paid by issuing 2.0 million shares of Class A common stock and remains subject to a $0.4 million contingent holdback. The APA, as amended, also provides for royalty payments of up to $21.3 million payable in cash or shares of Class A common stock at the Company's election until the earlier of the tenth anniversary date of the initial closing and the date on which the aggregate amount of the royalty payments equals the amount cap. The royalties are calculated based on 10% of the net licensing revenue and 40% of all consideration received for a license or sale of a product incorporating the acquired platform assets. No amounts for the royalty payments have been recorded during the three or nine months ended September 30, 2023. The Company routinely acquires rights to intellectual property that may provide for payment of future contingent consideration, including royalties, should revenue be generated from the use of such. Legal Proceedings From time to time, the Company may in the ordinary course of business be named as a defendant in lawsuits, indemnity claims and other legal proceedings. Except as described below, the Company does not believe any pending litigation to be material, or that the outcome of any such pending litigation, in management’s judgment based on information currently available, would have a material adverse effect on the Company’s results of operations, cash flows or financial condition. On August 4, 2021, a putative securities class action was filed on behalf of purchasers of the common stock of Zymergen, pursuant to or traceable to the registration statement for Zymergen’s initial public offering (“IPO”). The action is pending in the United States District Court for the Northern District of California, and is captioned Wang v. Zymergen Inc., et al., Case No. 3:21-cv-06028-VC. The action alleges violations of Sections 11 and 15 of the Securities Act of 1933, as amended (the “Securities Act”) in connection with Zymergen’s IPO, names Zymergen, certain of its former officers and directors, and its IPO underwriters as defendants and seeks damages in an unspecified amount, attorneys’ fees, and other remedies. On October 5, 2023, a Suggestion of Bankruptcy of Defendant Zymergen Inc. was filed in this action. On November 9, 2021, one of Zymergen’s then purported shareholders filed a putative derivative lawsuit in the United States District Court for the Northern District of California that is captioned Mellor v. Hoffman, et al., Case No. 3:21-cv-08723-VC. The complaint names certain of Zymergen’s former officers and directors as defendants and Zymergen as nominal defendant based on allegations substantially similar to those in the securities class action. The complaint purports to assert claims on Zymergen’s behalf for breach of fiduciary duty, unjust enrichment, abuse of control, gross mismanagement, corporate waste, and contribution under the federal securities laws and seeks corporate reforms, unspecified damages and restitution, and fees and costs. On October 5, 2023, a Suggestion of Bankruptcy of Defendant Zymergen Inc. was filed in this action. On or about February 7, 2023, a complaint was filed by Fortis Advisors LLC, solely in its capacity as Stockholders’ Representative for the holders of convertible promissory notes of Lodo Therapeutics Corporation (“Lodo”), against the Company's subsidiary, Zymergen, in Delaware Superior Court. The complaint purports to allege violations of California securities laws based on Zymergen’s exchange of its common stock for convertible promissory notes issued by Lodo in connection with Zymergen’s May 2021 acquisition of Lodo. The complaint seeks damages in an unspecified amount, attorneys’ fees, and other remedies. On October 5, 2023, a Suggestion of Bankruptcy of Defendant Zymergen Inc. was filed in this action. In addition, certain government agencies, including the SEC, have requested information related to Zymergen’s August 3, 2021 disclosure. Zymergen is cooperating fully.

Stock-Based Compensation

Stock-Based Compensation	9 Months Ended
	Sep. 30, 2023
Share-Based Payment Arrangement [Abstract]
Stock-Based Compensation	Stock-Based Compensation The following table summarizes stock-based compensation expense by financial statement line item in the Company’s condensed consolidated statement of operations and comprehensive loss for the periods presented (in thousands): Three Months Ended September 30, Nine Months Ended September 30, 2023 2022 2023 2022 Research and development $ 33,250 $ 186,864 $ 119,676 $ 664,710 General and administrative 19,323 376,273 67,371 1,157,762 Total $ 52,573 $ 563,137 $ 187,047 $ 1,822,472 The Company grants stock-based incentive awards pursuant to the 2021 Incentive Award Plan (the “2021 Plan”) and the 2022 Inducement Plan (the “2022 Inducement Plan”). As of September 30, 2023, there were approximately 189.0 million shares and 8.6 million shares available for future issuance under the 2021 Plan and 2022 Inducement Plan, respectively. Stock Options A summary of stock option activity for the nine months ended September 30, 2023 is presented below: Number of Shares (1) Weighted Average Exercise Price per Share Weighted Average Remaining Contractual Term Aggregate Intrinsic Value (2) (in thousands) (in years) (in thousands) Outstanding as of December 31, 2022 10,501 $ 0.34 Granted 979 1.90 Exercised (4,700) 0.02 Outstanding as of September 30, 2023 6,780 0.80 3.20 $ 8,609 Exercisable as of September 30, 2023 5,659 0.52 1.94 8,609 (1) Excludes 1.7 million shares underlying options issued outside the accounting for compensation awards under ASC 718. (2) The aggregate intrinsic value is calculated as the difference between the Company's closing stock price on the last trading day of the quarter and the exercise prices, multiplied by the number of in-the-money stock options. The aggregate intrinsic value of stock options exercised during the nine months ended September 30, 2023 and 2022 was $8.4 million and $18.8 million, respectively. During the nine months ended September 30, 2023 and 2022, the Company granted options with an aggregate fair value of $1.4 million and $1.8 million, respectively. The weighted-average fair value of options granted during the nine months ended September 30, 2023 and 2022 was $1.43 and $1.92 per share, respectively, and was calculated using the following key input assumptions in the Black-Scholes option-pricing model: Nine Months Ended September 30, 2023 2022 Risk-free interest rate 3.94 % 2.95 % Expected volatility 93 % 80 % Expected term (in years) 5.5 5.8 Dividend yield 0 % 0 % As of September 30, 2023, there was $1.4 million of unrecognized compensation expense related to stock options recognizable over a weighted-average period of 1 year. Restricted Stock and Restricted Stock Units During the nine months ended September 30, 2022, the Company cash settled approximately 3.2 million restricted stock units (“RSUs”) granted to non-employee directors for a total cash payment of $9.8 million. A summary of the RSU and restricted stock award (“RSA”) activity for the nine months ended September 30, 2023 is presented below: Restricted Stock Units Restricted Stock Awards Number of Weighted Number of Weighted Nonvested as of December 31, 2022 134,436 $ 5.84 4 $ 1.99 Granted 94,427 1.38 — — Vested (41,451) 6.54 (4) 1.99 Forfeited (18,646) 3.82 — — Nonvested as of September 30, 2023 168,766 3.39 — — The weighted average grant date fair value of RSUs granted during the nine months ended September 30, 2023 and 2022 was $1.38 and $3.68, respectively. No RSAs were granted during the nine months ended September 30, 2023 and 2022. The aggregate grant date fair value of the RSUs that vested during the nine months ended September 30, 2023 and 2022 was $271.2 million and $290.4 million, respectively. The aggregate grant date fair value of the RSAs that vested during the nine months ended September 30, 2023 and 2022 was de minimis. As of September 30, 2023, there was $355.9 million of unrecognized compensation expense related to RSUs recognizable over a weighted-average period of 3.1 years. Earnouts Earnout shares represent equity awards in the form of RSUs and RSAs that were granted to existing shareholders of the Company as of the closing date of the Company's merger with SRNG on September 16, 2021 (the “Closing Date”). The earnout shares are subject to the same terms and conditions as the underlying awards (including with respect to vesting and termination-related provisions). Additionally, the earnout shares are subject to a market condition that will be met when the trading price of the Company's common stock is greater than or equal to $12.50, $15.00, $17.50 and $20.00 for any 20 trading days within any period of 30 consecutive trading days, on or before the fifth anniversary of the Closing Date (collectively, the “Earnout Targets”). The first Earnout Target of $12.50 per share was met on November 15, 2021. A summary of activity during the nine months ended September 30, 2023 for the earnout shares is presented below: Number of Shares (in thousands) Weighted Average Grant Date Fair Value Nonvested as of December 31, 2022 23,520 $ 12.79 Vested (443) 13.34 Forfeited (289) 12.36 Nonvested as of September 30, 2023 22,788 12.78 The aggregate grant date fair value of the earnout shares that vested during the nine months ended September 30, 2023 and 2022 was $5.9 million and $8.3 million, respectively.

Revenue Recognition

Revenue Recognition	9 Months Ended
	Sep. 30, 2023
Revenue from Contract with Customer [Abstract]
Revenue Recognition	Revenue Recognition Disaggregation of Revenue The following table sets forth the percentage of Cell Engineering revenues by industry based on total Cell Engineering revenue: Three Months Ended September 30, Nine Months Ended September 30, 2023 2022 2023 2022 Pharma and biotech 30 % 33 % 33 % 21 % Food and nutrition 24 17 17 11 Agriculture 22 3 23 4 Industrial and environment 16 15 13 16 Government and defense 6 4 5 4 Consumer and technology 2 28 9 44 Total Cell Engineering revenue 100 % 100 % 100 % 100 % For the three months ended September 30, 2023 and 2022, the Company’s revenue from customers within the United States comprised 81% and 94%, respectively, of total revenue. For the nine months ended September 30, 2023 and 2022, the Company’s revenue from customers within the United States comprised 83% and 91%, respectively, of total revenue. Contract Balances The Company recognizes a contract asset when the Company transfers goods or services to a customer before the customer pays consideration or before payment is due, excluding any amounts presented as accounts receivable. The Company had no contract asset balances as of September 30, 2023 and December 31, 2022. Contract liabilities, or deferred revenue, primarily consist of payments received in advance of performance under the contract or when the Company has an unconditional right to consideration under the terms of the contract before it transfers goods or services to the customer. The Company’s collaborative arrangements with its investees and related parties typically include upfront payments consisting of cash or non-cash consideration for future research and development services and non-cash consideration in the form of convertible financial instruments and equity securities for licenses that will be transferred in the future. The Company records the upfront cash payments and fair value of the convertible financial instruments and equity securities as deferred revenue. The Company also invoices customers based on contractual billing schedules, which results in the recording of deferred revenue to the extent payment is received prior to the Company’s performance of the related services. Contract liabilities are recognized as revenue as (or when) the Company performs under the contract. During the nine months ended September 30, 2023, the Company recognized $59.8 million of revenue that was included in the contract liabilities balance of $222.6 million as of December 31, 2022. During the nine months ended September 30, 2022, the Company recognized $37.3 million of revenue that was included in the contract liabilities balance of $189.2 million as of December 31, 2021. Performance Obligations The aggregate amount of the transaction price that was allocated to performance obligations that have not yet been satisfied or are partially satisfied as of September 30, 2023 and December 31, 2022 was $116.9 million and $123.5 million, respectively. The Company has elected the practical expedient not to provide the remaining performance obligation disclosures related to contracts for which the Company recognizes revenue on a cost-plus basis in the amount to which it

Segment Information

Segment Information	9 Months Ended
	Sep. 30, 2023
Segment Reporting [Abstract]
Segment Information	Segment Information The Company has identified two operating and reportable segments: Cell Engineering and Biosecurity. The following table presents summary results of the Company’s reportable segments for the periods indicated (in thousands): Three Months Ended September 30, Nine Months Ended September 30, 2023 2022 (as adjusted)* 2023 2022 (as adjusted)* Revenue: Cell Engineering $ 37,176 $ 24,679 $ 116,555 $ 90,409 Biosecurity 18,254 41,719 100,145 289,012 Total revenue 55,430 66,398 216,700 379,421 Segment cost of revenue: Biosecurity 6,923 24,655 47,394 173,998 Segment research and development expense: Cell Engineering 90,889 65,589 275,494 177,948 Biosecurity 313 387 1,408 1,347 Total segment research and development expense 91,202 65,976 276,902 179,295 Segment general and administrative expense: Cell Engineering 42,617 41,606 155,216 104,900 Biosecurity 12,207 17,039 42,862 42,683 Total segment general and administrative expense 54,824 58,645 198,078 147,583 Segment operating (loss) income: Cell Engineering (96,330) (82,516) (314,155) (192,439) Biosecurity (1,189) (362) 8,481 70,984 Total segment operating loss (97,519) (82,878) (305,674) (121,455) Operating expenses not allocated to segments: Stock-based compensation (1) 53,647 563,385 191,324 1,829,690 Depreciation and amortization 21,060 8,917 57,670 26,885 Impairment of long-lived assets 112,403 — 121,404 — Change in fair value of contingent consideration liability 1,764 (242) 10,217 58 Loss from operations $ (286,393) $ (654,938) $ (686,289) $ (1,978,088) * As adjusted to reflect the impact of the adoption of ASC 842 as of January 1, 2022. See Note 1 for a summary of the adjustments. (1) Includes $1.1 million and $0.2 million in employer payroll taxes for the three months ended September 30, 2023 and 2022, respectively, and $4.3 million and $7.2 million in employer payroll taxes for the nine months ended September 30, 2023 and 2022, respectively.

Significant Collaboration Trans

Significant Collaboration Transactions	9 Months Ended
	Sep. 30, 2023
Revenue from Contract with Customer [Abstract]
Significant Collaboration Transactions	Significant Collaboration Transactions BiomEdit, LLC In April 2022, the Company, along with one of its investors and third-party investors, including Elanco Animal Health Inc. (“Elanco”), launched BiomEdit, LLC (“BiomEdit”), a microbiome innovation company that intends to discover, design and develop novel probiotics, microbiome derived bioactives and engineered microbial medicines in the field of animal health. Concurrently with the launch, the Company entered into (i) an Intellectual Property Contribution Agreement (“BiomEdit IP Agreement”) that granted BiomEdit a license to certain of the Company’s intellectual property, (ii) a Technical Development Agreement (“BiomEdit TDA”) that establishes the terms under which the Company will provide technical research and development services, and (iii) a Common Unit Issuance Agreement (“BiomEdit CUIA”) which compensates the Company for its intellectual property contribution. Contemporaneous with these agreements, BiomEdit entered into a Series A Preferred Unit Purchase Agreement under which it sold 6.7 million Series A preferred units to one of the Company’s investors and a third-party investor, for aggregate proceeds of approximately $32.5 million. After the initial closing, BiomEdit may issue up to an additional 1.5 million Series A preferred units (the “Additional Units”) to one or more purchasers reasonably acceptable to the existing holders of Series A preferred units. In a subsequent closing during the first quarter of 2023, BiomEdit sold 0.8 million Additional Units for aggregate proceeds of $4.0 million and closed its Series A preferred unit financing. Under the BiomEdit IP Agreement, the Company licensed certain intellectual property to BiomEdit for use in the development or production of BiomEdit’s products that the parties will subsequently agree to research and develop under technical development plans (“TDP”). The license rights provide BiomEdit with the ability to commercialize the specified products from the corresponding TDP under the BiomEdit TDA. In return for the license to the intellectual property, BiomEdit issued the Company 3.9 million common units upon execution of the BiomEdit CUIA, with 0.7 million of those units subject to forfeiture in the event BiomEdit does not sell all of the Additional Units. Under the BiomEdit TDA, the parties jointly agree on TDPs, through equal representation on a joint steering committee, under which the Company will perform agreed-upon research and development services in return for consideration on a fixed fee or cost-plus basis for all services provided. Accounting Analysis The common unit investment in BiomEdit is considered an equity method investment as a result of the Company’s ability to exercise significant influence over BiomEdit’s financial and operating policies through its ownership of common units. The initial carrying value of the equity method investment in BiomEdit is the fair value of the nonforfeitable common units of $8.9 million received in exchange for the BiomEdit IP Agreement which, as discussed below, is being accounted for as non-cash consideration under ASC 606. The Company determined that the 0.7 million common units held by Ginkgo subject to forfeiture are considered variable consideration that is fully constrained at contract inception until the contingencies related to the issuance of the additional shares are resolved. Upon the closing of BiomEdit's Series A preferred unit financing in the first quarter of 2023, Ginkgo forfeited 0.3 million common units and retained 0.4 million common units for total consideration of $1.1 million. The fair value of BiomEdit’s common units was determined at inception of the agreements using the option pricing method. The option pricing method used a back-solve methodology to infer the total equity value based on the pricing of the Series A preferred unit financing, which was contemporaneous with the BiomEdit IP Agreement. The Series A preferred units issued by BiomEdit receive a liquidation preference prior to common units. As such, the Company concluded that this represents a substantive profit-sharing arrangement, and the Company is recognizing earnings and losses on the equity method investment using the HLBV method. The Company recorded a $1.5 million loss on its equity method investment in BiomEdit during the nine months ended September 30, 2023, which reduced the carrying value of the equity method investment in BiomEdit to zero. There is no commitment for the Company to provide further financial support to BiomEdit, and therefore the carrying value of the equity method investment will not be reduced below zero. The relationship with BiomEdit is a vendor-customer relationship and is within the scope of ASC 606, as the provision of services and corresponding license rights are considered a part of the Company’s ordinary activities. The common units issued to the Company represent non-cash consideration. While the BiomEdit TDA has been executed by the parties and provides the payment terms for future services, the BiomEdit TDA does not provide for any transfer of goods or services between the parties. However, the Company will provide licenses and services upon execution of the contemplated TDPs. Accordingly, the Company concluded that the BiomEdit TDA, in combination with the BiomEdit CUIA, met the definition of a contract under ASC 606. Each TDP executed under the BiomEdit TDA will be accounted for in accordance with ASC 606. The Company’s performance obligations under the BiomEdit TDA consist of four material rights to future technical research and development services and commercial licenses under individual TDPs that the Company expects to execute. The material rights represent an advance payment for the license rights, which will be granted upon the execution of future TDPs. As there is no additional payment for these license rights when future TDPs are executed, the Company has determined that there is a material right associated with each of the contemplated TDPs under the BiomEdit TDA. The Company has allocated approximately $2.2 million of the upfront non-cash consideration to each of the four material rights based on the estimated standalone selling price of the performance obligations. During the first quarter of 2023, the additional $1.1 million of non-cash consideration, which represents previously constrained variable consideration, was allocated to each of the four performance obligations under the arrangement with BiomEdit of $0.3 million each consistent with the initial relative selling price allocation. Upon the execution of a TDP underlying a material right, the Company is obligated to provide technical research and development services under the TDP and a license to applicable patents and other intellectual property designed and developed under the TDP. The technical research and development services and license provided under a TDP are highly interdependent and interrelated with one another. Without the Company’s knowledge, expertise, and platform, there would not be a licensable strain or other commercializable product to transfer to BiomEdit. Further, BiomEdit has rights to intellectual property created as part of each TDP, irrespective of the result of the development. Therefore, each executed TDP underlying a material right consists of one combined performance obligation for the technical research and development services and license to be provided by the Company. For each TDP underlying a material right, the transaction price consists of (i) either a fixed fee or, if a cost-plus arrangement, variable consideration for the most likely amount of estimated consideration to be received and (ii) non-cash consideration allocated to the material rights. As the services performed by the Company under a TDP create or enhance an asset that BiomEdit controls as the asset is created or enhanced, the Company satisfies the performance obligation and recognizes revenue over time. The Company uses an input method that compares total costs incurred relative to total estimated cost to complete to estimate progress under the contract. Any revisions to the estimated total budgeted costs to complete, and the resulting impact on revenue recognition, are reflected in the period of the change through a cumulative catch-up adjustment. As of September 30, 2023 and December 31, 2022 the Company had a deferred revenue balance of $7.5 million and $8.1 million, respectively, with BiomEdit. During the three and nine months ended September 30, 2023, the Company recognized revenue of $0.6 million and $2.4 million, respectively, from services provided to BiomEdit.

Net Loss per Share

Net Loss per Share	9 Months Ended
	Sep. 30, 2023
Earnings Per Share [Abstract]
Net Loss per Share	Net Loss per Share The Company computes net loss per share of Class A common stock and Class B common stock using the two-class method required for participating securities. The earnings per share amounts are the same for the different classes of common stock because the holders of each class are legally entitled to equal per share distributions whether through dividends or liquidation. The following potential common shares, presented based on amounts outstanding at each period end, were excluded from the calculation of diluted net loss per share attributable to Ginkgo Bioworks Holdings, Inc. common stockholders for the periods presented because including them would have been anti-dilutive (in thousands): As of September 30, 2023 2022 Warrants to purchase Class A common stock 51,825 51,825 Outstanding stock options 8,420 19,541 Unvested RSUs 168,766 215,669 Unvested RSAs — 49 Earnout shares (1) 152,300 160,133 381,311 447,217

Related Parties

Related Parties	9 Months Ended
	Sep. 30, 2023
Related Party Transactions [Abstract]
Related Parties	Related Parties The Company’s significant transactions with its related parties are primarily comprised of revenue generating activities under collaboration and license agreements. Significant related party transactions included in the condensed consolidated balance sheet are summarized below (in thousands): As of September 30, As of December 31, 2023 2022 Accounts receivable: Allonnia, LLC $ 427 $ 140 Arcaea, LLC 6 335 Verb Biotics, LLC 337 361 Ayana Bio, LLC 381 403 BiomEdit, LLC 95 288 Other equity investees — 31 $ 1,246 $ 1,558 Deferred revenue, current and non-current: Motif FoodWorks, Inc. $ 45,752 $ 52,018 Genomatica, Inc. 3,251 6,250 Allonnia, LLC 35,920 35,876 Arcaea, LLC 33,256 38,334 BiomEdit, LLC 7,473 8,144 Ayana Bio 73 — Other equity investees 290 875 $ 126,015 $ 141,497 Significant related party transactions included in the condensed consolidated statement of operations and comprehensive loss are summarized below (in thousands): Three Months Ended September 30, Nine Months Ended September 30, 2023 2022 2023 2022 Cell Engineering revenue: Joyn Bio, LLC $ — $ 694 $ — $ 2,842 Motif FoodWorks, Inc. 6,303 83 6,306 1,930 Genomatica, Inc. 1,011 2,737 2,999 8,500 Allonnia, LLC 180 580 425 4,240 Arcaea, LLC — 4,014 5,669 10,311 Verb Biotics, LLC 70 825 588 1,763 Ayana Bio, LLC 326 685 961 685 BiomEdit, LLC 632 — 2,410 — Other equity investees 205 414 554 1,286 $ 8,727 $ 10,032 $ 19,912 $ 31,557

Subsequent Events

Subsequent Events	9 Months Ended
	Sep. 30, 2023
Subsequent Events [Abstract]
Subsequent Events	Subsequent Event On October 3, 2023, Zymergen and certain of its subsidiaries filed voluntary petitions for relief under Chapter 11 of the United States Bankruptcy Code (the “Zymergen Bankruptcy”) in the U.S. Bankruptcy Court for the District of Delaware (“Bankruptcy Court”). Neither the Company nor any of its other subsidiaries filed for bankruptcy protection, and the Company and its other subsidiaries will continue to operate their businesses as usual. Zymergen has been operated as a distinct legal entity, separate and apart from the Company, since it was acquired in October 2022. Shortly after its acquisition, the Company entered into an arms-length non-exclusive license with Zymergen with respect to Zymergen’s intellectual property, including its databases, automation, and software capabilities. The Zymergen Bankruptcy will not impact this non-exclusive license, and the Company’s rights under this license will not be affected. In connection with the Zymergen Bankruptcy, also on October 3, 2023, the Company entered into an asset purchase agreement with Zymergen (the “Zymergen APA”) as the stalking horse bidder under Section 363 of the U.S. Bankruptcy Code to acquire exclusive rights to substantially all of Zymergen’s intellectual property assets and certain other assets. The Company’s bid included a $5.0 million cash component and the potential assumption of a facility lease (currently included in the Company's consolidated financial statements) with a remaining minimum commitment of $37.4 million and a remaining lease term of approximately 9 years. The Company’s bid also included an undertaking by the Company to offer employment to 91 of Zymergen’s employees (provided such employees remain employed by Zymergen at the closing of the transactions contemplated by the Zymergen APA) whereby the Company would assume any post-closing employment obligations and maintain salary and certain employee benefits levels for a one-year period. The bid is subject to approval by the Bankruptcy Court, and a process under which Zymergen may consider alternative bids.

Basis of Presentation and Sum_2

Basis of Presentation and Summary of Significant Accounting Policies (Policies)	9 Months Ended
	Sep. 30, 2023
Accounting Policies [Abstract]
Basis of Presentation	Basis of Presentation The accompanying condensed consolidated financial statements have been prepared in conformity with the rules and regulations of the Securities and Exchange Commission and generally accepted accounting principles in the United States (“GAAP”) for interim financial reporting. Accordingly, certain detailed disclosures which would normally be included with annual financial statements have been omitted. In the opinion of management, all normal recurring adjustments necessary for a fair presentation have been made. These condensed consolidated financial statements should be read in conjunction with the Company's 2022 Annual Report on Form 10-K. Interim results are not necessarily indicative of results for a full year.
Principles of Consolidation	Principles of Consolidation The accompanying condensed consolidated financial statements include the accounts of the Company, its wholly owned subsidiaries, majority owned subsidiaries and variable interest entities if the Company is the primary beneficiary. All intercompany accounts and transactions have been eliminated.
Use of Estimates	Use of Estimates The preparation of financial statements in conformity with GAAP requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities, revenues and expenses, and the disclosure of contingent liabilities in the condensed consolidated financial statements. Estimates used in the preparation of these condensed consolidated financial statements include, among others, revenue recognition, stock-based compensation, the fair value of assets acquired and liabilities assumed in a business combination, the fair value of non-cash consideration received from customers, the fair value of certain notes receivable, the fair value of certain investments including equity method investments, the fair value of warrant liabilities, the allocation of equity method investment losses under the hypothetical liquidation at book value (“HLBV”) method, the incremental borrowing rate used in determining lease liabilities, impairment of long-lived assets, allowance for credit losses, accrued expenses and income taxes.
Recently Issued Accounting Pronouncements	Retrospective Application of a Change in Accounting Principle The Company adopted Accounting Standards Update No. 2016-02, Leases (“ASC 842”), which supersedes the guidance in Accounting Standards Codification Topic 840, Leases (“ASC 840”), effective January 1, 2022. As the Company elected the extended transition period for complying with new or revised accounting standards pursuant to Section 107(b) of the Jumpstart Our Business Startups Act of 2012, ASC 842 was adopted in connection with the preparation of the Company’s annual consolidated financial statements as of and for the year ended December 31, 2022. As such, the comparative information for the three and nine months ended September 30, 2022 has been adjusted herein to reflect the impact of the adoption of ASC 842 as of January 1, 2022. Recently Issued Accounting Pronouncements There were no new recently issued accounting pronouncements that are of significance or potential significance to the Company from those disclosed herein and within Note 2 to the Company's 2022 consolidated financial statements included in the 2022 Annual Report on Form 10-K.

Basis of Presentation and Sum_3

Basis of Presentation and Summary of Significant Accounting Policies (Tables)	9 Months Ended
	Sep. 30, 2023
Accounting Policies [Abstract]
Accounting Standards Update and Change in Accounting Principle	Select line items from the condensed consolidated statement of operations and comprehensive loss reflecting the adoption of ASC 842 are as follows (in thousands): Three Months Ended September 30, 2022 Nine Months Ended September 30, 2022 As Previously Reported Adjustments As Adjusted As Previously Reported Adjustments As Adjusted Costs and operating expenses: Research and development $ 259,580 $ 1,880 $ 261,460 $ 871,488 $ 3,607 $ 875,095 General and administrative 435,184 37 435,221 1,308,379 37 1,308,416 Total operating expenses 719,419 1,917 721,336 2,353,865 3,644 2,357,509 Loss from operations (653,021) (1,917) (654,938) (1,974,444) (3,644) (1,978,088) Other (expense) income: Interest income, net 5,820 560 6,380 7,097 1,724 8,821 Other income (expense), net (957) 281 (676) 629 844 1,473 Total other (expense) income, net (16,062) 841 (15,221) 41,969 2,568 44,537 Loss before income taxes (669,083) (1,076) (670,159) (1,932,475) (1,076) (1,933,551) Net loss (669,055) (1,076) (670,131) (1,932,218) (1,076) (1,933,294) Net loss attributable to Ginkgo Bioworks Holdings, Inc. stockholders (669,055) (1,076) (670,131) (1,928,385) (1,076) (1,929,461) Select line items from the condensed consolidated statements of stockholders’ equity reflecting the adoption of ASC 842 are as follows (in thousands): As of September 30, 2022 As Previously Reported Adjustments As Adjusted Accumulated deficit $ (4,226,310) $ 4,119 $ (4,222,191) Total stockholders' equity 1,439,736 4,119 1,443,855 Select line items from the condensed consolidated statements of cash flows reflecting the adoption of ASC 842 are as follows (in thousands): Nine Months Ended September 30, 2022 As Previously Reported Adjustments As Adjusted Cash flows from operating activities: Adjustments to reconcile net loss to net cash used in operating activities: Depreciation and amortization $ 28,602 $ (1,717) $ 26,885 Amortization of finance lease right-of-use assets (1) — 1,535 1,535 Non-cash lease expense — 11,877 11,877 Changes in operating assets and liabilities: Prepaid expenses and other current assets 5,849 (619) 5,230 Accounts payable, accrued expenses and other current liabilities (11,744) (108) (11,852) Operating lease liabilities, current and non-current — (7,807) (7,807) Deferred rent, non-current 2,255 (2,255) — Cash flows from financing activities: Principal payments on finance leases — (912) (912) Principal payments on capital leases and lease financing obligation (1,082) 1,082 —

Business Combination (Tables)

Business Combination (Tables)	9 Months Ended
	Sep. 30, 2023
Business Combination and Asset Acquisition [Abstract]
Summary of Consideration Paid, Common Stock and Contingent Consideration	The consideration paid was comprised of common stock and contingent consideration as follows (in thousands): Fair value of Class A common stock $ 17,015 Fair value of contingent consideration - restricted stock 3,842 Fair value of contingent consideration - milestones 8,464 Total FGen consideration $ 29,321
Schedule of Assets Acquired and Liabilities Assumed	The following table presents the final allocation of the purchase price to the assets acquired and liabilities assumed as of the acquisition date (in thousands): Final Allocation Cash and cash equivalents $ 1,430 Accounts receivable 144 Other non-current assets 10 Property and equipment 34 Intangible assets (1) 21,100 Goodwill (2) 10,615 Accounts payable and accrued expenses (29) Deferred revenue (104) Deferred tax liability (3,879) Net assets acquired $ 29,321 (1) Estimated useful life of 15 years.

Fair Value Measurements (Tables

Fair Value Measurements (Tables)	9 Months Ended
	Sep. 30, 2023
Fair Value Disclosures [Abstract]
Summary of Assets and Liabilities That Are Measured at Fair Value on Recurring Basis	The following tables present information about the Company’s financial assets and liabilities measured at fair value on a recurring basis (in thousands): As of September 30, 2023 Classification Total Level 1 Level 2 Level 3 Assets: Money market funds Cash and cash equivalents $ 1,019,232 $ 1,019,232 $ — $ — Synlogic, Inc. warrants (1) Investments 477 — 477 — Marketable equity securities (2) Investments 20,148 18,842 1,306 — Loan receivable Prepaid expenses and other current assets 100 — — 100 Notes receivable Other non-current assets 39,860 — 30,000 9,860 Total assets $ 1,079,817 $ 1,038,074 $ 31,783 $ 9,960 Liabilities: Public Warrants Warrant liabilities $ 7,934 $ 7,934 $ — $ — Private Placement Warrants (3) Warrant liabilities 4,321 — 125 4,196 Contingent consideration Accrued expenses and other current liabilities 23,838 — — 23,838 Contingent consideration Other non-current liabilities 7,488 — — 7,488 Total liabilities $ 43,581 $ 7,934 $ 125 $ 35,522 As of December 31, 2022 Classification Total Level 1 Level 2 Level 3 Assets: Money market funds Cash and cash equivalents $ 1,089,026 $ 1,089,026 $ — $ — Synlogic, Inc. warrants (1) Investments 1,937 — 1,937 — Marketable equity securities (2) Investments 25,714 21,312 4,402 — Notes receivable Other non-current assets 37,660 — 30,000 7,660 Total assets $ 1,154,337 $ 1,110,338 $ 36,339 $ 7,660 Liabilities: Public Warrants Warrant liabilities $ 6,900 $ 6,900 $ — $ — Private Placement Warrants (3) Warrant liabilities 3,968 — 108 3,860 Contingent consideration Accrued expenses and other current liabilities 6,378 — — 6,378 Contingent consideration Other non-current liabilities 18,095 — — 18,095 Total liabilities $ 35,341 $ 6,900 $ 108 $ 28,333 (1) The fair value of Synlogic, Inc. warrants is calculated as the quoted price of the underlying common stock, less the unpaid exercise price of the warrants. (2) Marketable equity securities classified as Level 2 reflect a discount for lack of marketability due to regulatory sales restrictions.
Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation	The following table provides a reconciliation of notes and loans receivable measured at fair value using Level 3 significant unobservable inputs for the nine months ended September 30 (in thousands): 2023 2022 Balance at January 1, $ 7,660 $ 11,559 Additions 4,106 — Change in fair value (1,806) 269 Balance at September 30, $ 9,960 $ 11,828
Summary of Fair Value Measurements Inputs	The following table provides quantitative information regarding Level 3 inputs used in the recurring valuation of the Private Placement Warrants as of their measurement dates: September 30, 2023 December 31, 2022 Exercise price $ 11.50 $ 11.50 Stock price $ 1.81 $ 1.69 Volatility 79.0 % 71.5 % Term (in years) 2.96 3.71 Risk-free interest rate 4.83 % 4.11 % The following table provides quantitative information regarding Level 3 inputs used in the fair value measurements of contingent consideration liabilities as of the periods presented: September 30, 2023 December 31, 2022 Contingent Consideration Liability Valuation Technique Unobservable Input Range Range Earnout payments (FGen, Dutch DNA, Circularis and Altar acquisitions) Probability-weighted present value Probability of payment 10% - 100% 2% - 100% Discount rate 14.5% - 15.3% 12.2% - 13.1% Earnout payments (Dutch DNA acquisition) Discounted cash flow Projected years of payments 2025 - 2028 2025 - 2028 Discount rate 11.5 % 12.0 %
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation	The following table provides a reconciliation of the Private Placement Warrants measured at fair value using Level 3 significant unobservable inputs for the nine months ended September 30 (in thousands): 2023 2022 Balance at January 1, $ 3,860 $ 58,558 Change in fair value 336 (43,658) Balance at September 30, $ 4,196 $ 14,900 The following table provides a reconciliation of the contingent consideration measured at fair value using Level 3 significant unobservable inputs for the nine months ended September 30 (in thousands): 2023 2022 Balance at January 1, $ 24,473 $ 8,467 Additions 1,397 13,150 Change in fair value 10,217 58 Settlements and payments (4,761) (2,644) Balance at September 30, $ 31,326 $ 19,031

Investments and Equity Method_2

Investments and Equity Method Investments (Tables)	9 Months Ended
	Sep. 30, 2023
Equity Method Investments and Joint Ventures [Abstract]
Schedule of Investments and Equity Method Investments	Investments and equity method investments consisted of the following (in thousands): As of September 30, As of December 31, 2023 2022 Investments: Genomatica, Inc. preferred stock $ 11,885 $ 44,885 Synlogic, Inc. common stock 1,188 4,819 Synlogic, Inc. warrants 477 1,937 Marketable equity securities 18,960 20,895 Non-marketable equity securities 27,631 17,544 SAFEs 24,829 22,108 Total $ 84,970 $ 112,188 Equity method investments (1) : BiomEdit, LLC $ — $ 369 Other 1,120 1,174 Total $ 1,120 $ 1,543 (1) Equity method investments in Platform Ventures with a carrying value of zero as of September 30, 2023 and December 31, 2022 were excluded from the table. (Losses) gains on investments and equity method investments consisted of the following (in thousands): Three Months Ended September 30, Nine Months Ended September 30, 2023 2022 2023 2022 (Loss) gain on investments: Synlogic, Inc. common stock $ (1,538) $ (1,268) $ (3,631) $ (9,321) Synlogic, Inc. warrants (618) (510) (1,459) (3,746) Genomatica, Inc. (33,000) — (33,000) (10,115) Marketable equity securities 460 215 (3,286) (16,604) Non-marketable equity securities (1,628) (195) (1,628) (195) SAFEs — — (1,811) — Total $ (36,324) $ (1,758) $ (44,815) $ (39,981) Loss on equity method investments: Joyn Bio, LLC $ — $ (5,226) $ — $ (15,637) Verb Biotics, LLC — — — (15,900) BiomEdit, LLC — (1,308) (1,462) (5,860) Ayana, LLC — (15,989) — (15,989) Other — (188) (54) (378) Total $ — $ (22,711) $ (1,516) $ (53,764)

Supplemental Financial Inform_2

Supplemental Financial Information (Tables)	9 Months Ended
	Sep. 30, 2023
Supplemental Financial Statement Information [Abstract]
Schedule of Cash, Cash Equivalents and Restricted Cash	The reconciliation of cash, cash equivalents and restricted cash reported within the condensed consolidated balance sheet to the totals shown within the condensed consolidated statement of cash flows is as follows (in thousands): As of September 30, 2023 2022 Cash and cash equivalents $ 1,049,244 $ 1,302,603 Restricted cash included in prepaid expenses and other current assets (1) 3,347 6,594 Restricted cash included in other non-current assets (1) 42,028 36,313 Total cash, cash equivalents and restricted cash $ 1,094,619 $ 1,345,510
Schedule of Cash and Cash Equivalents	The reconciliation of cash, cash equivalents and restricted cash reported within the condensed consolidated balance sheet to the totals shown within the condensed consolidated statement of cash flows is as follows (in thousands): As of September 30, 2023 2022 Cash and cash equivalents $ 1,049,244 $ 1,302,603 Restricted cash included in prepaid expenses and other current assets (1) 3,347 6,594 Restricted cash included in other non-current assets (1) 42,028 36,313 Total cash, cash equivalents and restricted cash $ 1,094,619 $ 1,345,510
Summary of Property and Equipment Net	Property, plant, and equipment, net consisted of the following (in thousands): As of September 30, As of December 31, 2023 2022 Lab equipment $ 147,043 $ 183,292 Leasehold improvements 83,177 125,307 Buildings and facilities 46,927 46,019 Construction in progress 15,099 23,426 Computer equipment and software 15,538 15,219 Furniture and fixtures 8,463 8,206 Land 6,060 6,060 Total property, plant, and equipment 322,307 407,529 Less: Accumulated depreciation and amortization (120,712) (92,756) Property, plant, and equipment, net $ 201,595 $ 314,773
Schedule of Capitalization	The following table presents the Company’s authorized, issued, and outstanding common stock as of the dates indicated (in thousands): Authorized Issued Outstanding Common stock as of September 30, 2023: Class A 10,500,000 1,612,729 1,497,104 Class B 4,500,000 379,141 355,621 Class C 800,000 120,000 120,000 15,800,000 2,111,870 1,972,725 Common stock as of December 31, 2022: Class A 10,500,000 1,448,234 1,337,499 Class B 4,500,000 383,649 354,477 Class C 800,000 200,000 200,000 15,800,000 2,031,883 1,891,976
Schedule of Supplemental Cash Flow Information	The following table presents non-cash investing and financing activities (in thousands): Nine Months Ended September 30, 2023 2022 (as adjusted)* Supplemental disclosure of non-cash investing and financing activities: ROU Asset obtained in exchange for new operating lease liabilities upon adoption of ASC 842 $ — $ 147,744 ROU Asset obtained in exchange for new finance lease liabilities upon adoption of ASC 842 — 3,397 ROU Asset obtained in exchange for new operating lease liabilities 13,770 75,198 ROU Asset obtained in exchange for new finance lease liabilities — 1,370 Purchases of property and equipment included in accounts payable and accrued expenses 1,563 7,959 Equity received in related parties — 8,873 Convertible financial instruments received for Cell Engineering services 5,595 13,689 Equity securities and warrants received for Cell Engineering services 13,843 3,423 Settlement of contingent consideration 3,222 — Common stock issued for business and asset acquisitions 3,581 24,607 Contingent consideration for business acquisition — 13,150 Deferred offering and acquisition costs in accounts payable and accrued expenses — 1,660 * As adjusted to reflect the impact of the adoption of ASC 842 as of January 1, 2022. See Note 1 for a summary of the adjustments.

Goodwill and Intangible Asset_2

Goodwill and Intangible Assets, net (Tables)	9 Months Ended
	Sep. 30, 2023
Goodwill and Intangible Assets Disclosure [Abstract]
Schedule of Goodwill	Changes in the carrying amount of goodwill consisted of the following (in thousands): Balance as of December 31, 2022 $ 60,210 Impact of foreign currency translation (180) Measurement period adjustments (1,973) Balance as of September 30, 2023 $ 58,057
Schedule of Intangible Assets	Intangible assets, net consisted of the following (in thousands): Gross Carrying Value (1) Accumulated Amortization (1) Net Weighted Average September 30, 2023: Developed technology $ 117,107 $ (20,341) $ 96,766 8.8 Database 3,700 (503) 3,197 6.0 Customer relationships 380 (214) 166 0.9 Assembled workforce 190 (151) 39 0.4 Total intangible assets $ 121,377 $ (21,209) $ 100,168 December 31, 2022: Developed technology $ 115,824 $ (8,825) $ 106,999 9.4 Database 3,700 (107) 3,593 6.8 Customer relationships 380 (71) 309 1.6 Assembled workforce 190 (50) 140 1.0 Total intangible assets $ 120,094 $ (9,053) $ 111,041
Schedule of Estimated Future Amortization Expense	Amortization expense was $4.0 million and $1.0 million for the three months ended September 30, 2023 and 2022, respectively, and $12.2 million and $2.3 million for the nine months ended September 30, 2023 and 2022, respectively. As of September 30, 2023, estimated future amortization expense for identifiable intangible assets is as follows (in thousands): Remainder of 2023 $ 3,938 2024 15,561 2025 15,437 2026 15,437 2027 12,362 Thereafter 37,433 Total $ 100,168

Stock Based Compensation (Table

Stock Based Compensation (Tables)	9 Months Ended
	Sep. 30, 2023
Share-Based Payment Arrangement [Abstract]
Summary of Stock-Based Compensation	The following table summarizes stock-based compensation expense by financial statement line item in the Company’s condensed consolidated statement of operations and comprehensive loss for the periods presented (in thousands): Three Months Ended September 30, Nine Months Ended September 30, 2023 2022 2023 2022 Research and development $ 33,250 $ 186,864 $ 119,676 $ 664,710 General and administrative 19,323 376,273 67,371 1,157,762 Total $ 52,573 $ 563,137 $ 187,047 $ 1,822,472
Summary of Stock Option Activity	A summary of stock option activity for the nine months ended September 30, 2023 is presented below: Number of Shares (1) Weighted Average Exercise Price per Share Weighted Average Remaining Contractual Term Aggregate Intrinsic Value (2) (in thousands) (in years) (in thousands) Outstanding as of December 31, 2022 10,501 $ 0.34 Granted 979 1.90 Exercised (4,700) 0.02 Outstanding as of September 30, 2023 6,780 0.80 3.20 $ 8,609 Exercisable as of September 30, 2023 5,659 0.52 1.94 8,609 (1) Excludes 1.7 million shares underlying options issued outside the accounting for compensation awards under ASC 718. (2) The aggregate intrinsic value is calculated as the difference between the Company's closing stock price on the last trading day of the quarter and the exercise prices, multiplied by the number of in-the-money stock options.
Summary of Key Input Assumptions in the Black-Scholes Option-Pricing	the following key input assumptions in the Black-Scholes option-pricing model: Nine Months Ended September 30, 2023 2022 Risk-free interest rate 3.94 % 2.95 % Expected volatility 93 % 80 % Expected term (in years) 5.5 5.8 Dividend yield 0 % 0 %
Summary of RSU and RSA Activity	A summary of the RSU and restricted stock award (“RSA”) activity for the nine months ended September 30, 2023 is presented below: Restricted Stock Units Restricted Stock Awards Number of Weighted Number of Weighted Nonvested as of December 31, 2022 134,436 $ 5.84 4 $ 1.99 Granted 94,427 1.38 — — Vested (41,451) 6.54 (4) 1.99 Forfeited (18,646) 3.82 — — Nonvested as of September 30, 2023 168,766 3.39 — —
Summary of Activity for Earnout RSA	A summary of activity during the nine months ended September 30, 2023 for the earnout shares is presented below: Number of Shares (in thousands) Weighted Average Grant Date Fair Value Nonvested as of December 31, 2022 23,520 $ 12.79 Vested (443) 13.34 Forfeited (289) 12.36 Nonvested as of September 30, 2023 22,788 12.78

Revenue Recognition (Tables)

Revenue Recognition (Tables)	9 Months Ended
	Sep. 30, 2023
Revenue from Contract with Customer [Abstract]
Disaggregation Of Revenue	The following table sets forth the percentage of Cell Engineering revenues by industry based on total Cell Engineering revenue: Three Months Ended September 30, Nine Months Ended September 30, 2023 2022 2023 2022 Pharma and biotech 30 % 33 % 33 % 21 % Food and nutrition 24 17 17 11 Agriculture 22 3 23 4 Industrial and environment 16 15 13 16 Government and defense 6 4 5 4 Consumer and technology 2 28 9 44 Total Cell Engineering revenue 100 % 100 % 100 % 100 %

Segment Information (Tables)

Segment Information (Tables)	9 Months Ended
	Sep. 30, 2023
Segment Reporting [Abstract]
Schedule of Segment Reporting Information, by Segment	The following table presents summary results of the Company’s reportable segments for the periods indicated (in thousands): Three Months Ended September 30, Nine Months Ended September 30, 2023 2022 (as adjusted)* 2023 2022 (as adjusted)* Revenue: Cell Engineering $ 37,176 $ 24,679 $ 116,555 $ 90,409 Biosecurity 18,254 41,719 100,145 289,012 Total revenue 55,430 66,398 216,700 379,421 Segment cost of revenue: Biosecurity 6,923 24,655 47,394 173,998 Segment research and development expense: Cell Engineering 90,889 65,589 275,494 177,948 Biosecurity 313 387 1,408 1,347 Total segment research and development expense 91,202 65,976 276,902 179,295 Segment general and administrative expense: Cell Engineering 42,617 41,606 155,216 104,900 Biosecurity 12,207 17,039 42,862 42,683 Total segment general and administrative expense 54,824 58,645 198,078 147,583 Segment operating (loss) income: Cell Engineering (96,330) (82,516) (314,155) (192,439) Biosecurity (1,189) (362) 8,481 70,984 Total segment operating loss (97,519) (82,878) (305,674) (121,455) Operating expenses not allocated to segments: Stock-based compensation (1) 53,647 563,385 191,324 1,829,690 Depreciation and amortization 21,060 8,917 57,670 26,885 Impairment of long-lived assets 112,403 — 121,404 — Change in fair value of contingent consideration liability 1,764 (242) 10,217 58 Loss from operations $ (286,393) $ (654,938) $ (686,289) $ (1,978,088) * As adjusted to reflect the impact of the adoption of ASC 842 as of January 1, 2022. See Note 1 for a summary of the adjustments. (1) Includes $1.1 million and $0.2 million in employer payroll taxes for the three months ended September 30, 2023 and 2022, respectively, and $4.3 million and $7.2 million in employer payroll taxes for the nine months ended September 30, 2023 and 2022, respectively.

Net Loss per Share (Tables)

Net Loss per Share (Tables)	9 Months Ended
	Sep. 30, 2023
Earnings Per Share [Abstract]
Summary of Anti-Dilutive Shares	The following potential common shares, presented based on amounts outstanding at each period end, were excluded from the calculation of diluted net loss per share attributable to Ginkgo Bioworks Holdings, Inc. common stockholders for the periods presented because including them would have been anti-dilutive (in thousands): As of September 30, 2023 2022 Warrants to purchase Class A common stock 51,825 51,825 Outstanding stock options 8,420 19,541 Unvested RSUs 168,766 215,669 Unvested RSAs — 49 Earnout shares (1) 152,300 160,133 381,311 447,217

Related Parties (Tables)

Related Parties (Tables)	9 Months Ended
	Sep. 30, 2023
Related Party Transactions [Abstract]
Summary of Condensed Consolidated Balance Sheets	Significant related party transactions included in the condensed consolidated balance sheet are summarized below (in thousands): As of September 30, As of December 31, 2023 2022 Accounts receivable: Allonnia, LLC $ 427 $ 140 Arcaea, LLC 6 335 Verb Biotics, LLC 337 361 Ayana Bio, LLC 381 403 BiomEdit, LLC 95 288 Other equity investees — 31 $ 1,246 $ 1,558 Deferred revenue, current and non-current: Motif FoodWorks, Inc. $ 45,752 $ 52,018 Genomatica, Inc. 3,251 6,250 Allonnia, LLC 35,920 35,876 Arcaea, LLC 33,256 38,334 BiomEdit, LLC 7,473 8,144 Ayana Bio 73 — Other equity investees 290 875 $ 126,015 $ 141,497
Summary of Condensed Consolidated Statements of Operations and Comprehensive Loss	Significant related party transactions included in the condensed consolidated statement of operations and comprehensive loss are summarized below (in thousands): Three Months Ended September 30, Nine Months Ended September 30, 2023 2022 2023 2022 Cell Engineering revenue: Joyn Bio, LLC $ — $ 694 $ — $ 2,842 Motif FoodWorks, Inc. 6,303 83 6,306 1,930 Genomatica, Inc. 1,011 2,737 2,999 8,500 Allonnia, LLC 180 580 425 4,240 Arcaea, LLC — 4,014 5,669 10,311 Verb Biotics, LLC 70 825 588 1,763 Ayana Bio, LLC 326 685 961 685 BiomEdit, LLC 632 — 2,410 — Other equity investees 205 414 554 1,286 $ 8,727 $ 10,032 $ 19,912 $ 31,557

Basis of Presentation and Sum_4

Basis of Presentation and Summary of Significant Accounting Policies - Summary of Statement of Operations and Comprehensive Loss Reflecting Adoption of ASC 842 (Details) - USD ($) $ in Thousands	3 Months Ended			9 Months Ended
	Sep. 30, 2023	Sep. 30, 2022		Sep. 30, 2023	Sep. 30, 2022
Costs and operating expenses:
Research and development	$ 156,662	$ 261,460	[1]	$ 463,583	$ 875,095	[1]
General and administrative	82,028	435,221	[1]	295,802	1,308,416	[1]
Total operating expenses	341,823	721,336	[1]	902,989	2,357,509	[1]
Loss from operations	(286,393)	(654,938)	[1],[2]	(686,289)	(1,978,088)	[1],[2]
Other (expense) income:
Interest income, net	15,020	6,380	[1]	43,914	8,821	[1]
Other income (expense), net	(2,893)	676	[1]	(9,045)	(1,473)	[1]
Total other (expense) income, net	(16,520)	(15,221)	[1]	5,241	44,537	[1]
Loss before income taxes	(302,913)	(670,159)	[1]	(681,048)	(1,933,551)	[1]
Net loss	(302,891)	(670,131)	[1]	(681,175)	(1,933,294)	[1],[3]
Net loss attributable to Ginkgo Bioworks Holdings, Inc. stockholders	$ (302,891)	(670,131)	[1]	$ (681,175)	(1,929,461)	[1]
As Previously Reported
Costs and operating expenses:
Research and development		259,580			871,488
General and administrative		435,184			1,308,379
Total operating expenses		719,419			2,353,865
Loss from operations		(653,021)			(1,974,444)
Other (expense) income:
Interest income, net		5,820			7,097
Other income (expense), net		957			(629)
Total other (expense) income, net		(16,062)			41,969
Loss before income taxes		(669,083)			(1,932,475)
Net loss		(669,055)			(1,932,218)
Net loss attributable to Ginkgo Bioworks Holdings, Inc. stockholders		(669,055)			(1,928,385)
Adjustments
Costs and operating expenses:
Research and development		1,880			3,607
General and administrative		37			37
Total operating expenses		1,917			3,644
Loss from operations		(1,917)			(3,644)
Other (expense) income:
Interest income, net		560			1,724
Other income (expense), net		(281)			(844)
Total other (expense) income, net		841			2,568
Loss before income taxes		(1,076)			(1,076)
Net loss		(1,076)			(1,076)
Net loss attributable to Ginkgo Bioworks Holdings, Inc. stockholders		$ (1,076)			$ (1,076)
[1] As adjusted to reflect the impact of the adoption of Accounting Standards Codification Topic 842, Leases (“ASC 842”) as of January 1, 2022. See Note 1 for a summary of the adjustments.

Basis of Presentation and Sum_5

Basis of Presentation and Summary of Significant Accounting Policies - Summary of Statement of Stockholders' Equity Reflecting Adoption of ASC 842 (Details) - USD ($) $ in Thousands	Sep. 30, 2023	Jun. 30, 2023	Dec. 31, 2022	Sep. 30, 2022		Jun. 30, 2022	Dec. 31, 2021
New Accounting Pronouncements or Change in Accounting Principle [Line Items]
Accumulated deficit	$ (5,078,834)		$ (4,397,659)	$ (4,222,191)
Total other (expense) income, net	$ 1,252,683	$ 1,503,585	$ 1,736,277	1,443,855	[1]	$ 1,572,251	$ 1,567,379
As Previously Reported
New Accounting Pronouncements or Change in Accounting Principle [Line Items]
Accumulated deficit				(4,226,310)
Total other (expense) income, net				1,439,736
Adjustments
New Accounting Pronouncements or Change in Accounting Principle [Line Items]
Accumulated deficit				4,119
Total other (expense) income, net				$ 4,119
[1]As adjusted to reflect the impact of the adoption of ASC 842 as of January 1, 2022. See Note 1 for a summary of the adjustments.

Basis of Presentation and Sum_6

Basis of Presentation and Summary of Significant Accounting Policies - Summary of Statement of Cash Flows Reflecting Adoption of ASC 842 (Details) - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2023	Sep. 30, 2022
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	$ 57,670	$ 26,885	[1]
Amortization of finance lease right-of-use assets (1)		1,535
Non-cash lease expense		11,877
Changes in operating assets and liabilities:
Prepaid expenses and other current assets	13,557	5,230	[1]
Accounts payable, accrued expenses and other current liabilities	(4,822)	(11,852)	[1]
Operating lease liabilities, current and non-current	(18,310)	(7,807)	[1]
Cash flows from financing activities:
Principal payments on capital leases and lease financing obligation	$ (977)	(912)	[1]
As Previously Reported
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization		28,602
Changes in operating assets and liabilities:
Prepaid expenses and other current assets		5,849
Accounts payable, accrued expenses and other current liabilities		(11,744)
Deferred rent, non-current		2,255
Cash flows from financing activities:
Principal payments on capital leases and lease financing obligation		(1,082)
Adjustments
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization		(1,717)
Amortization of finance lease right-of-use assets (1)		1,535
Non-cash lease expense		11,877
Changes in operating assets and liabilities:
Prepaid expenses and other current assets		(619)
Accounts payable, accrued expenses and other current liabilities		(108)
Operating lease liabilities, current and non-current		(7,807)
Deferred rent, non-current		(2,255)
Cash flows from financing activities:
Principal payments on capital leases and lease financing obligation		(912)
Principal payments on capital leases and lease financing obligation		$ 1,082
[1]As adjusted to reflect the impact of the adoption of ASC 842 as of January 1, 2022. See Note 1 for a summary of the adjustments.

Business Combination - Summary

Business Combination - Summary of Consideration Paid (Details) - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2023	Sep. 30, 2022	[1]
Business Acquisition [Line Items]
Total FGen consideration	$ 0	$ 13,150
FGen
Business Acquisition [Line Items]
Total FGen consideration	29,321
FGen | Contingent Consideration, Restricted Stock
Business Acquisition [Line Items]
Fair value of contingent consideration	3,842
FGen | Milestones
Business Acquisition [Line Items]
Fair value of contingent consideration	8,464
FGen | Common Class A
Business Acquisition [Line Items]
Fair value of Class A common stock	$ 17,015
[1]As adjusted to reflect the impact of the adoption of ASC 842 as of January 1, 2022. See Note 1 for a summary of the adjustments.

Business Combination - Addition

Business Combination - Additional Information (Details) - USD ($) $ / shares in Units, shares in Thousands, $ in Millions	3 Months Ended	9 Months Ended
	Jun. 30, 2022	Sep. 30, 2023	Dec. 31, 2022	Sep. 30, 2022
Business Acquisition [Line Items]
Common stock shares issued (in shares)		2,111,870	2,031,883
FGen
Business Acquisition [Line Items]
Contingent consideration				$ 1.7
Unrestricted Stock | FGen
Business Acquisition [Line Items]
Common stock shares issued (in shares)		4,000
Business acquire consideration		$ 17
Business acquisition, share price (in dollars per share)		$ 4.20
Restricted Stock Awards | FGen
Business Acquisition [Line Items]
Contingent consideration of restricted stock (in shares)		1,700
Shares forfeited (in shares)	$ 0.6
Common Class A
Business Acquisition [Line Items]
Common stock shares issued (in shares)		1,612,729	1,448,234
Common Class A | FGen
Business Acquisition [Line Items]
Common stock shares issued (in shares)		5,700

Business Combination - Schedule

Business Combination - Schedule of Assets Acquired and Liabilities Assumed (Details) - USD ($) $ in Thousands		Sep. 30, 2023	Apr. 01, 2022
Business Acquisition [Line Items]
Intangibles estimated useful life (in years)		15 years
FGen
Business Acquisition [Line Items]
Cash and cash equivalents			$ 1,430
Accounts receivable			144
Other non-current assets			10
Property and equipment			34
Intangible assets	[1]		21,100
Goodwill	[2]		10,615
Accounts payable and accrued expenses			(29)
Deferred revenue			(104)
Deferred tax liability			(3,879)
Net assets acquired			$ 29,321
[1]Estimated useful life of 15 years[2]Non-deductible for tax purposes.

Fair Value Measurements - Sched

Fair Value Measurements - Schedule of Financial Assets and Liabilities Measured at Fair Value (Details) - USD ($) $ in Thousands		Sep. 30, 2023	Dec. 31, 2022
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Total assets		$ 1,079,817	$ 1,154,337
Warrant liabilities		12,255	10,868
Contingent consideration		23,838	6,378
Contingent consideration		7,488	18,095
Total liabilities		43,581	35,341
Public Warrants
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Warrant liabilities		7,934	6,900
Private Placement Warrants
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Warrant liabilities	[1]	4,321	3,968
Loan receivable
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Receivables		100
Notes receivable
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Receivables		39,860	37,660
Synlogic, Inc. warrants
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Investments	[2]	477	1,937
Marketable equity securities
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Investments		20,148	25,714	[3]
Money market funds
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cash and cash equivalents		1,019,232	1,089,026
Level 1
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Total assets		1,038,074	1,110,338
Contingent consideration		0	0
Contingent consideration		0	0
Total liabilities		7,934	6,900
Level 1 | Public Warrants
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Warrant liabilities		7,934	6,900
Level 1 | Private Placement Warrants
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Warrant liabilities	[1]	0	0
Level 1 | Loan receivable
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Receivables		0
Level 1 | Notes receivable
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Receivables		0	0
Level 1 | Synlogic, Inc. warrants
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Investments	[2]	0	0
Level 1 | Marketable equity securities
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Investments		18,842	21,312	[3]
Level 1 | Money market funds
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cash and cash equivalents		1,019,232	1,089,026
Level 2
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Total assets		31,783	36,339
Contingent consideration		0	0
Contingent consideration		0	0
Total liabilities		125	108
Level 2 | Public Warrants
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Warrant liabilities		0	0
Level 2 | Private Placement Warrants
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Warrant liabilities	[1]	125	108
Level 2 | Loan receivable
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Receivables		0
Level 2 | Notes receivable
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Receivables		30,000	30,000
Level 2 | Synlogic, Inc. warrants
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Investments	[2]	477	1,937
Level 2 | Marketable equity securities
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Investments		1,306	4,402	[3]
Level 2 | Money market funds
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cash and cash equivalents		0	0
Level 3
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Total assets		9,960	7,660
Contingent consideration		23,838	6,378
Contingent consideration		7,488	18,095
Total liabilities		35,522	28,333
Level 3 | Public Warrants
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Warrant liabilities		0	0
Level 3 | Private Placement Warrants
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Warrant liabilities	[1]	4,196	3,860
Level 3 | Loan receivable
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Receivables		100
Level 3 | Notes receivable
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Receivables		9,860	7,660
Level 3 | Synlogic, Inc. warrants
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Investments	[2]	0	0
Level 3 | Marketable equity securities
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Investments		0	0	[3]
Level 3 | Money market funds
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cash and cash equivalents		$ 0	$ 0
[1]The fair value of Private Placement Warrants classified as Level 2 is equivalent to that of Public Warrants as the transfer of Private Placement Warrants to anyone other than the initial purchasers or any of their permitted transferees results in the Private Placement Warrants having substantially the same terms as the Public Warrants.[2]The fair value of Synlogic, Inc. warrants is calculated as the quoted price of the underlying common stock, less the unpaid exercise price of the warrants.[3]Marketable equity securities classified as Level 2 reflect a discount for lack of marketability due to regulatory sales restrictions.

Fair Value Measurements - Notes

Fair Value Measurements - Notes Receivable Narrative (Details)	9 Months Ended	12 Months Ended
	Sep. 30, 2023 USD ($)	Dec. 31, 2022 USD ($)
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Face amount of financing receivable purchased	$ 30,000,000	$ 30,000,000
Financing receivable	12,700,000	7,500,000
Financing receivable, fair value	$ 10,000,000
Significant Other Observable Inputs (Level 3) [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Financing receivable, fair value		$ 7,700,000
Measurement Input, Discount Rate
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Financing receivable, measurement input	0.17	0.125
Minimum | Measurement Input, Scenario Probabilities
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Financing receivable, measurement input	0.15	0.15
Minimum | Term (in years)
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Financing receivable, measurement input, period	1 year	1 year
Maximum | Measurement Input, Scenario Probabilities
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Financing receivable, measurement input	0.55	0.55
Maximum | Term (in years)
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Financing receivable, measurement input, period	3 years	3 years

Fair Value Measurements - Fair

Fair Value Measurements - Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation (Details) - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2023	Sep. 30, 2022
Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]
Balance at January 1,	$ 7,660	$ 11,559
Additions	4,106	0
Change in fair value	(1,806)	269
Balance at September 30,	$ 9,960	$ 11,828

Fair Value Measurements - Warra

Fair Value Measurements - Warrant Liabilities Narrative (Details) shares in Millions	Sep. 16, 2021 shares
Public Warrants
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Class of warrant or right, outstanding (in shares)	34.5
Private Placement Warrants
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Class of warrant or right, outstanding (in shares)	17.3

Fair Value Measurements - Summa

Fair Value Measurements - Summary of Fair Value Measurements Inputs (Detail)	Sep. 30, 2023 USD ($)	Dec. 31, 2022 USD ($)
Exercise price
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Fair value measurements inputs	11.50	11.50
Stock price
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Fair value measurements inputs	1.81	1.69
Volatility
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Fair value measurements inputs	79	71.5
Term (in years)
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Term (in years)	2 years 11 months 15 days	3 years 8 months 15 days
Risk-free interest rate
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Fair value measurements inputs	4.83	4.11

Fair Value Measurements - Fai_2

Fair Value Measurements - Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation (Details) - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2023	Sep. 30, 2022	Dec. 31, 2022	Dec. 31, 2021
Private Placement Warrants
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]
Balance at January 1,	$ 4,196	$ 14,900	$ 3,860	$ 58,558
Change in fair value	336	(43,658)
Balance at September 30,	4,196	14,900
Contingent Consideration
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]
Balance at January 1,	31,326	19,031	$ 24,473	$ 8,467
Additions	1,397	13,150
Change in fair value	10,217	58
Settlements and payments	(4,761)	(2,644)
Balance at September 30,	$ 31,326	$ 19,031

Fair Value Measurements - Conti

Fair Value Measurements - Contingent Consideration Narrative (Details) - USD ($) $ in Thousands, shares in Millions	9 Months Ended
	Sep. 30, 2023	Sep. 30, 2022	[1]	Oct. 31, 2023	Dec. 31, 2022	Oct. 31, 2022	Apr. 30, 2022	Jul. 31, 2021
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Contingent consideration	$ 23,838				$ 6,378
Contingent consideration payment	$ 1,082	$ 521
Clinical trial milestone achievement, period	5 years
Subsequent Event
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Contingent consideration				$ 2,500
FGen AG
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Other non-current liabilities							$ 20,000
Dutch Dna Biotech Bv
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Other non-current liabilities								$ 20,000
Circularis Biotechnologies, Inc
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Other non-current liabilities						$ 37,500
Circularis Biotechnologies, Inc | Restricted Stock Awards
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Other non-current liabilities	$ 4,800
Contingent consideration payment	$ 1,500
Issuance of common stock for asset acquisition (in shares)	1.6
Business combination, vesting of restricted shares, value	$ 3,200
Loss on fair value of contingent consideration	1,400
Altar SAS
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Payment for achievement of a technical development milestone	$ 2,500
[1]As adjusted to reflect the impact of the adoption of ASC 842 as of January 1, 2022. See Note 1 for a summary of the adjustments.

Fair Value Measurements - Quant

Fair Value Measurements - Quantitative Information Regarding Level 3 Inputs (Details) - Fair Value, Recurring	Sep. 30, 2023	Dec. 31, 2022
Discounted cash flow
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Discount rate	11.50%	12%
Maximum | Probability-weighted present value
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Discount rate	100%	100%
Maximum | Discounted cash flow
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Discount rate	15.30%	13.10%
Minimum | Probability-weighted present value
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Discount rate	10%	2%
Minimum | Discounted cash flow
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Discount rate	14.50%	12.20%

Fair Value Measurements - Nonre

Fair Value Measurements - Nonrecurring Fair Value Measurements Narrative (Details) $ in Thousands	3 Months Ended			9 Months Ended
	Sep. 30, 2023 USD ($)	Sep. 30, 2022 USD ($)	[1]	Sep. 30, 2023 USD ($)	Sep. 30, 2022 USD ($)	[1]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Impairment loss				$ 1,800
Adjustments from observable price changes, downward price adjustment				0
Revenue from customers as prepayment for Cell Engineering	$ 55,430	$ 66,398		216,700	$ 379,421
Genomatica Inc Preferred Stocks
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Impairment loss	33,000			33,000
Adjustments from observable price changes, downward price adjustment	$ 1,600			1,600
SAFE
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Revenue from customers as prepayment for Cell Engineering				$ 11,000
Measurement Input, Discount Rate
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Equity securities, measurement input	0.14			0.14
Level 3
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Fair value of customers obligations	$ 4,500			$ 4,500
Minimum | Measurement Input, Scenario Probabilities
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Equity securities, measurement input	0.20			0.20
Minimum | Term (in years)
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Equity securities, measurement input, term				1 year
Minimum | Measurement Input, Probability Weighted
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Equity securities, measurement input	0.15			0.15
Maximum | Measurement Input, Scenario Probabilities
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Equity securities, measurement input	0.60			0.60
Maximum | Term (in years)
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Equity securities, measurement input, term				2 years
Maximum | Measurement Input, Probability Weighted
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Equity securities, measurement input	0.85			0.85
[1] As adjusted to reflect the impact of the adoption of Accounting Standards Codification Topic 842, Leases (“ASC 842”) as of January 1, 2022. See Note 1 for a summary of the adjustments.

Investments and Equity Method_3

Investments and Equity Method Investments - Additional Information (Details) - USD ($) $ in Millions	3 Months Ended		9 Months Ended
	Sep. 30, 2023	Sep. 30, 2022	Sep. 30, 2023	Sep. 30, 2022
Net Investment Income [Line Items]
Impairment loss			$ 1.8
Adjustments from observable price changes, downward price adjustment			0
Adjustments from observable price changes, upward price adjustment			0
Genomatica Inc Preferred Stocks
Net Investment Income [Line Items]
Asset impairment	$ 33		33	$ 10.1
Impairment loss	33		33
Adjustments from observable price changes, downward price adjustment	$ 1.6		1.6
SAFEs
Net Investment Income [Line Items]
Impairment loss		$ 0	$ 1.8	$ 0

Investments and Equity Method_4

Investments and Equity Method Investments - Schedule of Investments and Equity Method Investments (Details) - USD ($)		3 Months Ended			9 Months Ended
		Sep. 30, 2023	Sep. 30, 2022		Sep. 30, 2023	Sep. 30, 2022		Dec. 31, 2022
Net Investment Income [Line Items]
Total		$ 84,970,000			$ 84,970,000			$ 112,188,000
Equity method investments	[1]	1,120,000			1,120,000			1,543,000
(Loss) gain on investments:		(36,324,000)	$ (1,758,000)	[2]	(44,815,000)	$ (39,981,000)	[2]
Loss on equity method investments:		0	(22,711,000)	[2]	(1,516,000)	(53,764,000)	[2]
Genomatica, Inc. preferred stock
Net Investment Income [Line Items]
Equity securities		11,885,000			11,885,000			44,885,000
Synlogic, Inc. common stock
Net Investment Income [Line Items]
Equity securities		1,188,000			1,188,000			4,819,000
(Loss) gain on investments:		(1,538,000)	(1,268,000)		(3,631,000)	(9,321,000)
Synlogic, Inc. warrants
Net Investment Income [Line Items]
Equity securities		477,000			477,000			1,937,000
(Loss) gain on investments:		(618,000)	(510,000)		(1,459,000)	(3,746,000)
Marketable equity securities
Net Investment Income [Line Items]
Equity securities		18,960,000			18,960,000			20,895,000
(Loss) gain on investments:		460,000	215,000		(3,286,000)	(16,604,000)
Non-marketable equity securities
Net Investment Income [Line Items]
Equity securities		27,631,000			27,631,000			17,544,000
(Loss) gain on investments:		(1,628,000)	(195,000)		(1,628,000)	(195,000)
SAFEs
Net Investment Income [Line Items]
SAFEs		24,829,000			24,829,000			22,108,000
(Loss) gain on investments:		0	0		(1,811,000)	0
BiomEdit, LLC
Net Investment Income [Line Items]
Equity method investments	[1]	0			0			369,000
Loss on equity method investments:		0	(1,308,000)		(1,462,000)	(5,860,000)
Other
Net Investment Income [Line Items]
Equity method investments	[1]	1,120,000			1,120,000			1,174,000
Loss on equity method investments:		0	(188,000)		(54,000)	(378,000)
Genomatica, Inc.
Net Investment Income [Line Items]
(Loss) gain on investments:		(33,000,000)	0		(33,000,000)	(10,115,000)
Joyn Bio, LLC
Net Investment Income [Line Items]
Loss on equity method investments:		0	(5,226,000)		0	(15,637,000)
Verb Biotics, LLC
Net Investment Income [Line Items]
Loss on equity method investments:		0	0		0	(15,900,000)
Ayana, LLC
Net Investment Income [Line Items]
Loss on equity method investments:		0	$ (15,989,000)		0	$ (15,989,000)
Platform Ventures
Net Investment Income [Line Items]
Equity method investments		$ 0			$ 0			$ 0
[1]Equity method investments in Platform Ventures with a carrying value of zero as of September 30, 2023 and December 31, 2022 were excluded from the table.[2] As adjusted to reflect the impact of the adoption of Accounting Standards Codification Topic 842, Leases (“ASC 842”) as of January 1, 2022. See Note 1 for a summary of the adjustments.

Variable Interest Entities - Ad

Variable Interest Entities - Additional Information (Details) - USD ($) $ in Thousands	3 Months Ended			9 Months Ended
	Sep. 30, 2023	Sep. 30, 2022		Sep. 30, 2023	Sep. 30, 2022
Variable Interest Entity [Line Items]
Gain on deconsolidation of subsidiaries	$ 0	$ 15,989	[1]	$ 0	$ 31,889	[1],[2]
Verb Biotics, LLC
Variable Interest Entity [Line Items]
Gain on deconsolidation of subsidiaries		$ 16,000
Ayana Bio, LLC
Variable Interest Entity [Line Items]
Gain on deconsolidation of subsidiaries					$ 31,900
Cooksonia
Variable Interest Entity [Line Items]
Controls of board of directors				100%
[1] As adjusted to reflect the impact of the adoption of Accounting Standards Codification Topic 842, Leases (“ASC 842”) as of January 1, 2022. See Note 1 for a summary of the adjustments.

Supplemental Financial Inform_3

Supplemental Financial Information - Cash, Cash Equivalents and Restricted Cash (Details) - USD ($) $ in Thousands		Sep. 30, 2023	Dec. 31, 2022	Sep. 30, 2022		Dec. 31, 2021	[1]
Supplemental Financial Statement Information [Abstract]
Cash and cash equivalents		$ 1,049,244	$ 1,315,792	$ 1,302,603	[1]	$ 1,550,004
Restricted cash included in prepaid expenses and other current assets	[2]	3,347		6,594
Restricted cash included in other non-current assets	[2]	42,028		36,313
Cash, cash equivalents and restricted cash, end of period		$ 1,094,619	$ 1,369,581	$ 1,345,510	[1]	$ 1,592,928
[1]As adjusted to reflect the impact of the adoption of ASC 842 as of January 1, 2022. See Note 1 for a summary of the adjustments.[2]Includes cash balances collateralizing letters of credit associated with the Company’s facility leases and a customer prepayment requiring segregation and restrictions in its use in accordance with the customer agreement.

Supplemental Financial Inform_4

Supplemental Financial Information - Summary of Property, Plant, and Equipment, Net (Detail) - USD ($) $ in Thousands	Sep. 30, 2023	Dec. 31, 2022
Property, Plant and Equipment [Line Items]
Total property, plant, and equipment	$ 322,307	$ 407,529
Less: Accumulated depreciation and amortization	(120,712)	(92,756)
Property, plant, and equipment, net	201,595	314,773
Lab equipment
Property, Plant and Equipment [Line Items]
Total property, plant, and equipment	147,043	183,292
Leasehold improvements
Property, Plant and Equipment [Line Items]
Total property, plant, and equipment	83,177	125,307
Buildings and facilities
Property, Plant and Equipment [Line Items]
Total property, plant, and equipment	46,927	46,019
Construction in progress
Property, Plant and Equipment [Line Items]
Total property, plant, and equipment	15,099	23,426
Computer equipment and software
Property, Plant and Equipment [Line Items]
Total property, plant, and equipment	15,538	15,219
Furniture and fixtures
Property, Plant and Equipment [Line Items]
Total property, plant, and equipment	8,463	8,206
Land
Property, Plant and Equipment [Line Items]
Total property, plant, and equipment	$ 6,060	$ 6,060

Supplemental Financial Inform_5

Supplemental Financial Information - Additional Information (Details) ft² in Thousands, $ in Thousands, shares in Millions			1 Months Ended	3 Months Ended		9 Months Ended
	May 09, 2023 USD ($) shares	Apr. 03, 2023 shares	Sep. 30, 2023 USD ($) ft²	Sep. 30, 2023 USD ($)	Sep. 30, 2022 USD ($)	Sep. 30, 2023 USD ($) facility	Sep. 30, 2022 USD ($)
Supplemental Financial Information [Line Items]
Number of faciliites | facility						2
Leased facility, square feet | ft²			300
Operating lease, impairment loss			$ 96,200	$ 96,210	$ 0	$ 96,210	$ 0
Operating lease, discount rate			8.50%	8.50%		8.50%
Lab equipment
Supplemental Financial Information [Line Items]
Impairment charges				$ 16,200		$ 25,200
Building
Supplemental Financial Information [Line Items]
Operating lease, impairment loss			$ 36,600
Leasehold improvements
Supplemental Financial Information [Line Items]
Operating lease, impairment loss			$ 59,600
Common Class A
Supplemental Financial Information [Line Items]
Issuance of common stock for asset acquisition (in shares) | shares		2.8
Common stock issued for employee retention payments (in shares) | shares	2
Common stock issued for employee retention payments	$ 2,500

Supplemental Financial Inform_6

Supplemental Financial Information - Capitalization (Details) - shares shares in Thousands	Sep. 30, 2023	Dec. 31, 2022
Supplemental Financial Information [Line Items]
Common stock, shares authorized (in shares)	15,800,000	15,800,000
Common stock shares issued (in shares)	2,111,870	2,031,883
Common stock, shares outstanding (in shares)	1,972,725	1,891,976
Class A
Supplemental Financial Information [Line Items]
Common stock, shares authorized (in shares)	10,500,000	10,500,000
Common stock shares issued (in shares)	1,612,729	1,448,234
Common stock, shares outstanding (in shares)	1,497,104	1,337,499
Class B
Supplemental Financial Information [Line Items]
Common stock, shares authorized (in shares)	4,500,000	4,500,000
Common stock shares issued (in shares)	379,141	383,649
Common stock, shares outstanding (in shares)	355,621	354,477
Class C
Supplemental Financial Information [Line Items]
Common stock, shares authorized (in shares)	800,000	800,000
Common stock shares issued (in shares)	120,000	200,000
Common stock, shares outstanding (in shares)	120,000	200,000

Supplemental Financial Inform_7

Supplemental Financial Information - Schedule of Supplemental Cash Flow Information (Details) - USD ($) $ in Thousands	3 Months Ended	9 Months Ended
	Sep. 30, 2023	Sep. 30, 2023	Sep. 30, 2022
Supplemental Financial Information [Line Items]
ROU Asset obtained in exchange for new operating lease liabilities		$ 13,770	$ 75,198	[1]
ROU Asset obtained in exchange for new finance lease liabilities		0	1,370	[1]
Purchases of property and equipment included in accounts payable and accrued expenses		1,563	7,959	[1]
Equity received in related parties		0	8,873	[1]
Convertible financial instruments received for Cell Engineering services		5,595	13,689	[1]
Equity securities and warrants received for Cell Engineering services		13,843	3,423	[1]
Settlement of contingent consideration	$ 960	3,222	0	[1]
Common stock issued for business and asset acquisitions		3,581	24,607	[1]
Contingent consideration for business acquisition		0	13,150	[1]
Deferred offering and acquisition costs in accounts payable and accrued expenses		0	1,660
Accounting Standards Update 2016-02
Supplemental Financial Information [Line Items]
ROU Asset obtained in exchange for new operating lease liabilities		0	147,744	[1]
ROU Asset obtained in exchange for new finance lease liabilities		$ 0	$ 3,397	[1]
[1]As adjusted to reflect the impact of the adoption of ASC 842 as of January 1, 2022. See Note 1 for a summary of the adjustments.

Goodwill and Intangible Asset_3

Goodwill and Intangible Assets, net - Schedule of Goodwill (Details) $ in Thousands	9 Months Ended
	Sep. 30, 2023 USD ($)
Goodwill [Roll Forward]
Balance as of December 31, 2022	$ 60,210
Impact of foreign currency translation	(180)
Measurement period adjustments	(1,973)
Balance as of September 30, 2023	$ 58,057

Goodwill and Intangible Asset_4

Goodwill and Intangible Assets, net - Additional Information (Details) - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2023	Sep. 30, 2022	[1]	Dec. 31, 2022
Goodwill [Line Items]
Increase to accounts receivable	$ (21,168)	$ (20,521)
Goodwill	58,057			$ 60,210
Zymergen
Goodwill [Line Items]
Goodwill, period increase (decrease)	2,200
Increase to accounts receivable	1,800
Decrease in other current liabilities	400
Altar SAS acquisition
Goodwill [Line Items]
Goodwill	$ 200
[1]As adjusted to reflect the impact of the adoption of ASC 842 as of January 1, 2022. See Note 1 for a summary of the adjustments.

Goodwill and Intangible Asset_5

Goodwill and Intangible Assets, net - Schedule of Intangible Assets (Details) - USD ($) $ in Thousands		9 Months Ended	12 Months Ended
		Sep. 30, 2023	Dec. 31, 2022
Acquired Finite-Lived Intangible Assets [Line Items]
Gross Carrying Value	[1]	$ 121,377	$ 120,094
Accumulated Amortization	[1]	21,209	9,053
Total		100,168	111,041
Developed technology
Acquired Finite-Lived Intangible Assets [Line Items]
Gross Carrying Value	[1]	117,107	115,824
Accumulated Amortization	[1]	20,341	8,825
Total		$ 96,766	$ 106,999
Weighted Average Amortization Period		8 years 9 months 18 days	9 years 4 months 24 days
Database
Acquired Finite-Lived Intangible Assets [Line Items]
Gross Carrying Value	[1]	$ 3,700	$ 3,700
Accumulated Amortization	[1]	503	107
Total		$ 3,197	$ 3,593
Weighted Average Amortization Period		6 years	6 years 9 months 18 days
Customer relationships
Acquired Finite-Lived Intangible Assets [Line Items]
Gross Carrying Value	[1]	$ 380	$ 380
Accumulated Amortization	[1]	214	71
Total		$ 166	$ 309
Weighted Average Amortization Period		10 months 24 days	1 year 7 months 6 days
Assembled workforce
Acquired Finite-Lived Intangible Assets [Line Items]
Gross Carrying Value	[1]	$ 190	$ 190
Accumulated Amortization	[1]	151	50
Total		$ 39	$ 140
Weighted Average Amortization Period		4 months 24 days	1 year
[1]Gross carrying value and accumulated amortization include the impact of cumulative foreign currency translation adjustments.

Goodwill and Intangible Asset_6

Goodwill and Intangible Assets, net - Schedule of Amortization expense (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2023	Sep. 30, 2022	Sep. 30, 2023	Sep. 30, 2022	Dec. 31, 2022
Goodwill and Intangible Assets Disclosure [Abstract]
Amortization expense	$ 4,000	$ 1,000	$ 12,200	$ 2,300
Remainder of 2023	3,938		3,938
2024	15,561		15,561
2025	15,437		15,437
2026	15,437		15,437
2027	12,362		12,362
Thereafter	37,433		37,433
Total	$ 100,168		$ 100,168		$ 111,041

Commitments and Contingencies (

Commitments and Contingencies (Detail) $ in Thousands			1 Months Ended	3 Months Ended			9 Months Ended
	Aug. 29, 2023	Apr. 03, 2023 shares	Oct. 31, 2023 USD ($)	Sep. 30, 2023 USD ($)	Sep. 30, 2022 USD ($) shares		Sep. 30, 2023 USD ($) shares	Sep. 30, 2022 USD ($) shares
Commitments and Contingencies
Unrecorded unconditional purchase obligation, term (in years)	5 years
Unrecorded unconditional purchase obligation, year one				$ 8,000			$ 8,000
Unrecorded unconditional purchase obligation, year two				28,000			28,000
Unrecorded unconditional purchase obligation, year three				54,000			54,000
Unrecorded unconditional purchase obligation, year four				86,000			86,000
Unrecorded unconditional purchase obligation, year five				113,000			113,000
Unrecorded unconditional purchase obligation				289,000			289,000
Research and development				156,662	$ 261,460	[1]	463,583	$ 875,095	[1]
StrideBio
Commitments and Contingencies
Payments for royalties				$ 0			$ 0
Royalty received from licensing revenue				10			10
Royalty received from license or sale of a product				40			40
Google Cloud | Cloud and Artificial Intelligence
Commitments and Contingencies
Revenue, remaining performance obligation, variable consideration amount				$ 56,300			$ 56,300
Google Cloud | Cloud and Artificial Intelligence | Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date [Axis]: 2023-10-01
Commitments and Contingencies
Revenue, remaining performance obligation, expected timing of satisfaction, period (in years)				3 years			3 years
Common Class A
Commitments and Contingencies
Issuance of common stock for asset acquisition (in shares) | shares		2,800,000
Common Class A | StrideBio
Commitments and Contingencies
Fair value of assets acquired							$ 4,000
Issuance of common stock for asset acquisition (in shares) | shares							2,800,000
Common Class A | StrideBio | Subsequent Event
Commitments and Contingencies
Asset acquisition, consideration transferred			$ 3,800
Asset acquisition, consideration transferred, equity interest			2,000
Contingent consideration			400
Payments for royalties			$ 21,300
Common Stock
Commitments and Contingencies
Issuance of common stock for asset acquisition (in shares) | shares					2,588,000		2,820,000	8,142,000
Common Stock | StrideBio
Commitments and Contingencies
Research and development							$ 400
Common Stock | Common Class A | StrideBio
Commitments and Contingencies
Research and development							$ 3,600
[1] As adjusted to reflect the impact of the adoption of Accounting Standards Codification Topic 842, Leases (“ASC 842”) as of January 1, 2022. See Note 1 for a summary of the adjustments.

Stock-Based Compensation - Cond

Stock-Based Compensation - Condensed Consolidated Statements of Operations and Comprehensive Loss (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2023	Sep. 30, 2022	Sep. 30, 2023	Sep. 30, 2022
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Total	$ 52,573	$ 563,137	$ 187,047	$ 1,822,472
Research and development
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Total	33,250	186,864	119,676	664,710
General and administrative
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Total	$ 19,323	$ 376,273	$ 67,371	$ 1,157,762

Stock-Based Compensation - Addi

Stock-Based Compensation - Additional Information (Detail) - USD ($) $ / shares in Units, shares in Thousands, $ in Millions		9 Months Ended
	Sep. 16, 2021	Sep. 30, 2023	Sep. 30, 2022	Nov. 15, 2021
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Aggregate intrinsic value of stock options exercised		$ 8.4	$ 18.8
Options with an aggregate fair value		$ 1.4	$ 1.8
Options, grants in period, weighted average grant date fair value (in dollars per share)		$ 1.43	$ 1.92
New Ginkgo Earn-out shares
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Unrecognized compensation expense		$ 6.5
Unrecognized stock-based compensation recognition period		1 year 5 months 23 days
New Ginkgo Earn-out shares | Maximum
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Share-based payment award, award vesting period	30 days
New Ginkgo Earn-out shares | Minimum
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Share-based payment award, award vesting period	20 days
Non-Employee
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Cash payment in plan modification			$ 9.8
Outstanding stock options
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Unrecognized compensation expense		$ 1.4
Unrecognized stock-based compensation recognition period		1 year
Restricted Stock Units
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Options, grants in period, weighted average grant date fair value (in dollars per share)		$ 1.38	$ 3.68
Unrecognized compensation expense		$ 355.9
Unrecognized stock-based compensation recognition period		3 years 1 month 6 days
Cash payment in plan modification			$ 3.2
Granted (in shares)		94,427
Fair value of restricted stock awards vested		$ 271.2	$ 290.4
Restricted Stock Awards
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Granted (in shares)		0	0
Earnout RSU
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Fair value of restricted stock awards vested		$ 5.9	$ 8.3
12.50 Then 25%
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Share price (in dollars per share)				$ 12.50
12.50 Then 25% | Common Stock | New Ginkgo Earn-out shares
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Share price (in dollars per share)	$ 12.50
15.00 Then 25% | Common Stock | New Ginkgo Earn-out shares
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Share price (in dollars per share)	15
17.50 Then 25% | Common Stock | New Ginkgo Earn-out shares
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Share price (in dollars per share)	17.50
20.00 Then 25% | Common Stock | New Ginkgo Earn-out shares
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Share price (in dollars per share)	$ 20
2021 Incentive Award Plan
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Common stock reserved for issuance (in shares)		189,000
2022 Inducement Plan
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Common stock reserved for issuance (in shares)		8,600

Stock-Based Compensation - Summ

Stock-Based Compensation - Summary of Stock Option Activity (Details) $ / shares in Units, shares in Thousands, $ in Thousands	9 Months Ended
	Sep. 30, 2023 USD ($) $ / shares shares
Number of Shares
Outstanding, beginning balance (in shares)	10,501	[1]
Granted (in shares)	979	[1]
Exercised (in shares)	(4,700)	[1]
Outstanding, ending balance (in shares)	6,780	[1]
Exercisable, ending balance (in shares)	5,659	[1]
Weighted Average Exercise Price per Share
Beginning balance (in dollars per share) | $ / shares	$ 0.34
Granted (in dollars per share) | $ / shares	1.90
Exercised (in dollars per share) | $ / shares	0.02
Ending balance (in dollars per share) | $ / shares	0.80
Exercisable (in dollars per share) | $ / shares	$ 0.52
Weighted Average Remaining Contractual Term
Outstanding (in years)	3 years 2 months 12 days
Exercisable (in years)	1 year 11 months 8 days
Aggregate Intrinsic Value
Outstanding | $	$ 8,609	[2]
Exercisable | $	$ 8,609	[2]
Underlying options issued (in shares)	1,700
[1]Excludes 1.7 million shares underlying options issued outside the accounting for compensation awards under ASC 718.[2]The aggregate intrinsic value is calculated as the difference between the Company's closing stock price on the last trading day of the quarter and the exercise prices, multiplied by the number of in-the-money stock options.

Stock-Based Compensation - Key

Stock-Based Compensation - Key Input Assumptions in the Black-Scholes Option-Pricing Model (Details) - USD ($)	9 Months Ended
	Sep. 30, 2023	Sep. 30, 2022
Share-Based Payment Arrangement [Abstract]
Risk-free interest rate	3.94%	2.95%
Expected volatility	93%	80%
Expected term (in years)	5 years 6 months	5 years 9 months 18 days
Dividend yield	$ 0	$ 0

Stock-Based Compensation - Shar

Stock-Based Compensation - Share-based Payment Arrangement, Restricted Stock Unit, Activity (Details) - $ / shares shares in Thousands	9 Months Ended
	Sep. 30, 2023	Sep. 30, 2022
Restricted Stock Units
Number of Shares (in thousands)
Nonvested, beginning balance (in shares)	134,436
Granted (in shares)	94,427
Vested (in shares)	(41,451)
Forfeited (in shares)	(18,646)
Nonvested, ending balance (in shares)	168,766
Weighted Average Grant Date Fair Value
Nonvested beginning balance (in dollars per share)	$ 5.84
Granted (in dollars per share)	1.38
Vested (in dollars per share)	6.54
Forfeited (in dollars per share)	3.82
Nonvested ending balance (in dollars per share)	$ 3.39
Restricted Stock Awards
Number of Shares (in thousands)
Nonvested, beginning balance (in shares)	4
Granted (in shares)	0	0
Vested (in shares)	(4)
Forfeited (in shares)	0
Nonvested, ending balance (in shares)	0
Weighted Average Grant Date Fair Value
Nonvested beginning balance (in dollars per share)	$ 1.99
Granted (in dollars per share)	0
Vested (in dollars per share)	1.99
Forfeited (in dollars per share)	0
Nonvested ending balance (in dollars per share)	$ 0

Stock-Based Compensation - Su_2

Stock-Based Compensation - Summary of Earnout Shares (Details) - Earnout RSU shares in Thousands	9 Months Ended
	Sep. 30, 2023 $ / shares shares
Number of Shares (in thousands)
Nonvested, beginning balance (in shares) | shares	23,520
Vested (in shares) | shares	(443)
Forfeited (in shares) | shares	(289)
Nonvested, ending balance (in shares) | shares	22,788
Weighted Average Grant Date Fair Value
Nonvested beginning balance (in dollars per share) | $ / shares	$ 12.79
Vested (in dollars per share) | $ / shares	13.34
Forfeited (in dollars per share) | $ / shares	12.36
Nonvested ending balance (in dollars per share) | $ / shares	$ 12.78

Revenue Recognition - Disaggreg

Revenue Recognition - Disaggregation of Revenue (Details) - Revenue from Contract with Customer Benchmark - Product Concentration Risk	3 Months Ended		9 Months Ended
	Sep. 30, 2023	Sep. 30, 2022	Sep. 30, 2023	Sep. 30, 2022
Cell Engineering
Disaggregation of Revenue [Line Items]
Total	100%	100%	100%	100%
Pharma and biotech
Disaggregation of Revenue [Line Items]
Total	30%	33%	33%	21%
Agriculture
Disaggregation of Revenue [Line Items]
Total	22%	3%	23%	4%
Consumer and technology
Disaggregation of Revenue [Line Items]
Total	2%	28%	9%	44%
Food and nutrition
Disaggregation of Revenue [Line Items]
Total	24%	17%	17%	11%
Industrial and environment
Disaggregation of Revenue [Line Items]
Total	16%	15%	13%	16%
Government and defense
Disaggregation of Revenue [Line Items]
Total	6%	4%	5%	4%

Revenue Recognition - Additiona

Revenue Recognition - Additional Information (Details) - USD ($) $ in Millions	3 Months Ended		9 Months Ended
	Sep. 30, 2023	Sep. 30, 2022	Sep. 30, 2023	Sep. 30, 2022	Dec. 31, 2022	Dec. 31, 2021
Disaggregation of Revenue [Line Items]
Contract asset	$ 0		$ 0		$ 0
Contract with customer, revenue recognized			59.8	$ 37.3
Deferred revenue, current and non-current:					222.6	$ 189.2
Revenue, remaining performance obligation, amount	$ 116.9		$ 116.9		$ 123.5
UNITED STATES | Customer Concentration Risk | Revenue from Contract with Customer Benchmark
Disaggregation of Revenue [Line Items]
Revenue from customers within the United States	81%	94%	83%	91%

Segment Information Schedule of

Segment Information Schedule of Segment Reporting Information, by Segment (Details) - USD ($) $ in Thousands		3 Months Ended			9 Months Ended
		Sep. 30, 2023	Sep. 30, 2022		Sep. 30, 2023	Sep. 30, 2022
Revenue:
Total revenue		$ 55,430	$ 66,398	[1]	$ 216,700	$ 379,421	[1]
Segment research and development expense:
Total segment research and development expense		156,662	261,460	[1]	463,583	875,095	[1]
Segment general and administrative expense:
General and administrative		82,028	435,221	[1]	295,802	1,308,416	[1]
Segment operating income (loss):
Total segment operating loss		(286,393)	(654,938)	[1],[2]	(686,289)	(1,978,088)	[1],[2]
Operating expenses not allocated to segments:
Stock-based compensation					187,047	1,822,472	[3]
Depreciation and amortization					57,670	26,885	[3]
Employer payroll taxes		1,100	200		4,300	7,200
Corporate, Non-Segment
Operating expenses not allocated to segments:
Stock-based compensation	[4]	53,647	563,385	[2]	191,324	1,829,690	[2]
Depreciation and amortization		21,060	8,917	[2]	57,670	26,885	[2]
Asset impairment		112,403	0	[2]	121,404	0	[2]
Change in fair value of contingent consideration liability		1,764	(242)	[2]	10,217	58	[2]
Cell Engineering and Biosecurity
Revenue:
Total revenue		55,430	66,398	[2]	216,700	379,421	[2]
Segment research and development expense:
Total segment research and development expense		91,202	65,976	[2]	276,902	179,295	[2]
Segment general and administrative expense:
General and administrative		54,824	58,645	[2]	198,078	147,583	[2]
Segment operating income (loss):
Total segment operating loss		(97,519)	(82,878)	[2]	(305,674)	(121,455)	[2]
Cell Engineering | Operating Segments
Revenue:
Total revenue		37,176	24,679	[2]	116,555	90,409	[2]
Segment research and development expense:
Total segment research and development expense		90,889	65,589	[2]	275,494	177,948	[2]
Segment general and administrative expense:
General and administrative		42,617	41,606	[2]	155,216	104,900	[2]
Segment operating income (loss):
Total segment operating loss		(96,330)	(82,516)	[2]	(314,155)	(192,439)	[2]
Biosecurity | Operating Segments
Revenue:
Total revenue		18,254	41,719	[2]	100,145	289,012	[2]
Segment cost of revenue:
Total segment cost of revenue		6,923	24,655	[2]	47,394	173,998	[2]
Segment research and development expense:
Total segment research and development expense		313	387	[2]	1,408	1,347	[2]
Segment general and administrative expense:
General and administrative		12,207	17,039	[2]	42,862	42,683	[2]
Segment operating income (loss):
Total segment operating loss		$ (1,189)	$ (362)	[2]	$ 8,481	$ 70,984	[2]
[1] As adjusted to reflect the impact of the adoption of Accounting Standards Codification Topic 842, Leases (“ASC 842”) as of January 1, 2022. See Note 1 for a summary of the adjustments.

Segment Information - Additiona

Segment Information - Additional Information (Details)	9 Months Ended
	Sep. 30, 2023 segment
Segment Reporting [Abstract]
Number of operating segments	2
Number of reportable segments	2

Significant Collaboration Tra_2

Significant Collaboration Transactions - Additional Information (Details) shares in Millions		1 Months Ended	3 Months Ended					9 Months Ended
		Apr. 30, 2022 USD ($) shares	Sep. 30, 2023 USD ($) materialRight obligation shares	Jun. 30, 2023 USD ($) shares	Mar. 31, 2023 USD ($) shares	Sep. 30, 2022 USD ($)		Sep. 30, 2023 USD ($) materialRight obligation shares	Sep. 30, 2022 USD ($)		Dec. 31, 2022 USD ($)	Dec. 31, 2021 USD ($)
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Total FGen consideration								$ 0	$ 13,150,000	[1]
Loss on equity method investments			$ 0			$ (22,711,000)	[2]	(1,516,000)	(53,764,000)	[2]
Carrying value of equity method investment	[3]		1,120,000					1,120,000			$ 1,543,000
Revenue, remaining performance obligation, amount			116,900,000					116,900,000			123,500,000
Deferred revenue											222,600,000	$ 189,200,000
Revenue from customers as prepayment for Cell Engineering			$ 55,430,000			66,398,000	[2]	216,700,000	379,421,000	[2]
BiomEdit, LLC
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Allocated upfront non-cash consideration								$ 2,200,000
Number of material rights | materialRight			4					4
Additional non-cash consideration				$ 1,100,000
Number of performance obligations | obligation			4					4
Revenue, remaining performance obligation, amount			$ 300,000					$ 300,000
Deferred revenue			$ 7,500,000					7,500,000			8,100,000
Revenue from customers as prepayment for Cell Engineering								$ 600,000	2,400,000
BiomEdit, LLC
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Common units (in shares) | shares			0.7					0.7
Shares issued, forfeited (in shares) | shares				0.3
Equity method investment, amount sold								$ 8,900,000
Common units, outstanding (in shares) | shares				0.4
Loss on equity method investments			$ 0			$ (1,308,000)		(1,462,000)	$ (5,860,000)
Carrying value of equity method investment	[3]		$ 0					0			$ 369,000
BiomEdit, LLC
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Total FGen consideration		$ 32,500,000			$ 4,000,000
Additional preferred units issued (in shares) | shares					0.8
Common units (in shares) | shares		3.9
Shares issued, forfeited (in shares) | shares		0.7
Series A Preferred Stock | BiomEdit, LLC
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Allocated upfront non-cash consideration				$ 1,100,000
Loss on equity method investments								$ 1,500,000
Series A Preferred Stock | BiomEdit, LLC
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Business combination, shares sold (in shares) | shares		6.7
Business combination, additional preferred shares sold (in shares) | shares		1.5
[1]As adjusted to reflect the impact of the adoption of ASC 842 as of January 1, 2022. See Note 1 for a summary of the adjustments.[2] As adjusted to reflect the impact of the adoption of Accounting Standards Codification Topic 842, Leases (“ASC 842”) as of January 1, 2022. See Note 1 for a summary of the adjustments.

Net Loss per Share (Details)

Net Loss per Share (Details) - shares		9 Months Ended
		Sep. 30, 2023	Sep. 30, 2022
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Shares excluded from the computation of diluted loss per share (in shares)		381,311,000	447,217
Investments
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Shares excluded from the computation of diluted loss per share (in shares)		51,825,000	51,825
Outstanding stock options
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Shares excluded from the computation of diluted loss per share (in shares)		8,420,000	19,541
Unvested RSUs
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Shares excluded from the computation of diluted loss per share (in shares)		168,766,000	215,669
Unvested RSAs
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Shares excluded from the computation of diluted loss per share (in shares)		0	49
Earnout shares
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Shares excluded from the computation of diluted loss per share (in shares)	[1]	152,300,000	160,133
[1]Represents earnout shares for which the service-based vesting conditions and/or market conditions have not been met.

Related Parties - Summary of Co

Related Parties - Summary of Condensed Consolidated Balance Sheets (Details) - USD ($) $ in Thousands	Sep. 30, 2023	Dec. 31, 2022	Dec. 31, 2021
Related Party Transaction [Line Items]
Accounts receivable:	$ 1,246	$ 1,558
Deferred revenue, current and non-current:		222,600	$ 189,200
Related party
Related Party Transaction [Line Items]
Accounts receivable:	1,246	1,558
Deferred revenue, current and non-current:	126,015	141,497
Related party | Allonnia, LLC
Related Party Transaction [Line Items]
Accounts receivable:	427	140
Deferred revenue, current and non-current:	35,920	35,876
Related party | Arcaea, LLC
Related Party Transaction [Line Items]
Accounts receivable:	6	335
Deferred revenue, current and non-current:	33,256	38,334
Related party | Verb Biotics, LLC
Related Party Transaction [Line Items]
Accounts receivable:	337	361
Related party | Ayana Bio, LLC
Related Party Transaction [Line Items]
Accounts receivable:	381	403
Deferred revenue, current and non-current:	73	0
Related party | BiomEdit, LLC
Related Party Transaction [Line Items]
Accounts receivable:	95	288
Deferred revenue, current and non-current:	7,473	8,144
Related party | Other equity investees
Related Party Transaction [Line Items]
Accounts receivable:	0	31
Deferred revenue, current and non-current:	290	875
Related party | Motif FoodWorks, Inc.
Related Party Transaction [Line Items]
Deferred revenue, current and non-current:	45,752	52,018
Related party | Genomatica, Inc.
Related Party Transaction [Line Items]
Deferred revenue, current and non-current:	$ 3,251	$ 6,250

Related Parties - Summary of _2

Related Parties - Summary of Condensed Consolidated Statements of Operations and Comprehensive Loss (Details) - USD ($) $ in Thousands	3 Months Ended			9 Months Ended
	Sep. 30, 2023	Sep. 30, 2022		Sep. 30, 2023	Sep. 30, 2022
Related Party Transaction [Line Items]
Cell Engineering revenue:	$ 55,430	$ 66,398	[1]	$ 216,700	$ 379,421	[1]
Related party
Related Party Transaction [Line Items]
Cell Engineering revenue:	8,727	10,032		19,912	31,557
Related party | Joyn Bio, LLC
Related Party Transaction [Line Items]
Cell Engineering revenue:	0	694		0	2,842
Related party | Motif FoodWorks, Inc.
Related Party Transaction [Line Items]
Cell Engineering revenue:	6,303	83		6,306	1,930
Related party | Genomatica, Inc.
Related Party Transaction [Line Items]
Cell Engineering revenue:	1,011	2,737		2,999	8,500
Related party | Allonnia, LLC
Related Party Transaction [Line Items]
Cell Engineering revenue:	180	580		425	4,240
Related party | Arcaea, LLC
Related Party Transaction [Line Items]
Cell Engineering revenue:	0	4,014		5,669	10,311
Related party | Verb Biotics, LLC
Related Party Transaction [Line Items]
Cell Engineering revenue:	70	825		588	1,763
Related party | Ayana Bio, LLC
Related Party Transaction [Line Items]
Cell Engineering revenue:	326	685		961	685
Related party | BiomEdit, LLC
Related Party Transaction [Line Items]
Cell Engineering revenue:	632	0		2,410	0
Related party | Other equity investees
Related Party Transaction [Line Items]
Cell Engineering revenue:	$ 205	$ 414		$ 554	$ 1,286
[1] As adjusted to reflect the impact of the adoption of Accounting Standards Codification Topic 842, Leases (“ASC 842”) as of January 1, 2022. See Note 1 for a summary of the adjustments.

Subsequent Events (Details)

Subsequent Events (Details) - Zymergen - Subsequent Event $ in Millions		3 Months Ended
	Oct. 03, 2023 USD ($)	Dec. 31, 2023 USD ($) employee
Subsequent Event [Line Items]
Asset acquisition, price of acquisition, expected	$ 5
Forecast 2023
Subsequent Event [Line Items]
Number of employees acquired | employee		91
Lease term (in years)		9 years
Operating lease, liability		$ 37.4
Asset acquisition, post-closing employment obligations, period		1 year

Uncategorized Items - dna-20230

Label	Element	Value
Accounting Standards Update [Extensible Enumeration]	us-gaap_AccountingStandardsUpdateExtensibleList	Accounting Standards Update 2016-02 [Member]