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 | | ATTORNEYS AT LAW |
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| | CLIENT/MATTER NUMBER |
| | 129722-0103 |
September 21, 2022
Ms. Abby Adams
Office of Life Sciences
Division of Corporation Finance
U.S. Securities and Exchange Commission
100 F Street NE
Washington, DC 20549
| Re: | LMF Acquisition Opportunities, Inc. |
| | Amendment No. 3 to Registration Statement on Form S-4 |
Dear Ms. Adams:
On behalf of our client, LMF Acquisition Opportunities, Inc. (the “Company” or “LMAO”), set forth below are the responses of the Company to the comments of the Staff (the “Staff”) of the Securities and Exchange Commission set forth in the Staff’s letter, dated September 19, 2022, with respect to the above-referenced filing. The numbered items set forth below repeat (in bold italics) the comments of the Staff reflected in the comment letter, and following such comments are the responses of the Company (in regular type). Concurrently herewith, the Company is filing Amendment No. 4 to the Registration Statement on Form S-4 (the “Amended Registration Statement”) that reflects the responses to your comments. In addition, we are delivering to the Staff clean and marked courtesy copies of the Amended Registration Statement. Capitalized terms used but not defined in this letter have the meanings given to such terms in the Amended Registration Statement. References to page numbers in this letter are to page numbers in the Amended Registration Statement.
Amendment No. 3 to Registration Statement on Form S-4
SeaStar Medical’s Business
Clinical Studies, page 177
1. | We reissue comment 6 insofar as you have not provided all serious adverse events for (1) the AKI Safety, Mortality and Device Integrity Study on page 177, for which you provide a non-exclusive list of serious adverse events, and (2) the Pilot Feasibility Trial of SCD Therapy in ESRD Patients on page 181, for which you state “very few adverse events or SAEs were observed,” without further specifying all serious adverse events. |
Response:
In response to the Staff’s comment, the Company has revised the disclosure on pages 177 and 182 of the Amended Registration Statement to (1) clarify that there were no serious adverse events for the AKI Safety, Mortality and Device Integrity Study, and (2) list all serious adverse events for the Pilot Feasibility Trial of SCD Therapy in ESRD Patients in a tabular format.
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