Exhibit 99.1
Joint Filing Agreement
The undersigned acknowledge and agree that the foregoing statement on Schedule 13G is filed on behalf of each of the undersigned and that all subsequent amendments to this statement on Schedule 13G shall be filed on behalf of each of the undersigned without the necessity of filing additional joint filing statements. The undersigned acknowledge that each shall be responsible for the timely filing of such amendments, and for the completeness and accuracy of the information concerning him, her or it contained herein, but shall not be responsible for the completeness and accuracy of the information concerning the other entities or persons, except to the extent that he, she or it knows or has reason to believe that such information is inaccurate.
| Coöperatieve Aescap Venture I U.A. |
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| By: | /s/Patrick Krol | /s/Hans Bosman |
| | Name: Aescap Venture Management B.V., represented by Patrick Krol and Hans Bosman |
| | Title: Managing Directors |
| Aescap Venture Management B.V. |
| |
| By: | /s/Patrick Krol | /s/Hans Bosman |
| | Name: Patrick Krol and Hans Bosman |
| | Title: Managing Directors |
| Patrick Johan Hendrik Krol |
| |
| By: | /s/Patrick Johan Hendrik Krol |
| Johan Gerhard Bosman |
| |
| By: | /s/Johan Gerhard Bosman |
| Michiel Alexander de Haan |
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| By: | /s/Michiel Alexander de Haan |